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1. 发明授权

US06333162B1 Method for measuring cholinesterase and method for distinguishing between liver cirrhosis and hepatitis 失效
标题翻译：胆碱酯酶测定方法及肝硬化与肝炎鉴别方法
公开(公告)号：US06333162B1
公开(公告)日：2001-12-25
申请号：US08632326
申请日：1996-04-17
申请人： Masahide Kondo , Kiyoshi Yasukawa , Toshikazu Hada
发明人： Masahide Kondo , Kiyoshi Yasukawa , Toshikazu Hada
IPC分类号： C12Q100
CPC分类号： C07K16/40 , G01N33/573
摘要： The object of the present invention is to provide method for discriminating between liver cirrhosis and chronic hepatitis by serodiagnosis using a simple enzyme immunoassay method without performing histopathological examinations by biopsy and so forth. The present invention discloses an enzyme immunoassay method for cholinesterase using monoclonal antibody, a method for detecting Aleuria aurantia lectin-reactive cholinesterase using monoclonal antibody and Aleuria aurantia lectin, and a method for discriminating between liver cirrhosis and chronic hepatitis on the basis of those results.
摘要翻译：本发明的目的是提供使用简单的酶免疫测定法通过血清诊断法鉴别肝硬化和慢性肝炎的方法，而不通过活组织检查等进行组织病理学检查。本发明公开了使用单克隆抗体的胆碱酯酶的酶免疫测定方法，基于这些结果，使用单克隆抗体和Aleuria aurantia凝集素检测Aleuria aurantia凝集素反应性胆碱酯酶的方法以及鉴别肝硬化和慢性肝炎的方法。

2. 发明授权

US08178720B2 Method for producing unsaturated aldehyde and unsaturated carboxylic acid 有权
标题翻译：不饱和醛和不饱和羧酸的制备方法
公开(公告)号：US08178720B2
公开(公告)日：2012-05-15
申请号：US12281694
申请日：2007-03-06
申请人： Masahide Kondo , Seiichi Kawato , Toru Kuroda
发明人： Masahide Kondo , Seiichi Kawato , Toru Kuroda
IPC分类号： C07C51/00 , C07C51/16
CPC分类号： C07C51/252 , B01J23/002 , B01J37/0009 , B01J37/0045 , B01J2523/00 , C07C45/35 , C07C45/37 , C07C51/235 , C07C47/22 , C07C57/04 , B01J2523/15 , B01J2523/27 , B01J2523/53 , B01J2523/54 , B01J2523/68 , B01J2523/842 , B01J2523/845
摘要： Disclosed is a method of a gas-phase catalytic oxidation reaction of propylene, isobutylene, or tertiary butanol with molecular oxygen in the presence of a catalyst to produce a corresponding unsaturated aldehyde and a corresponding unsaturated carboxylic acid, in which the catalyst can be used over a long period of time. Concretely, in the presence of the catalyst containing a complex oxide including molybdenum, bismuth and iron as essential components, at least one factor of a reaction pressure and a molar ratio of molecular oxygen to a raw material is controlled to change in such a way that a rate of reaction of the raw material is kept constant in the temperature range of from (TA−15)° C. to TA° C., when a boundary temperature of the activation energy of the catalyst is set to be TA° C.
摘要翻译：公开了在催化剂存在下丙烯，异丁烯或叔丁醇与分子氧的气相催化氧化反应的方法，以产生相应的不饱和醛和相应的不饱和羧酸，其中可以使用催化剂很长一段时间。具体地说，在含有包含钼，铋和铁作为必要成分的复合氧化物的催化剂的存在下，控制至少一个反应压力因子和分子氧与原料的摩尔比，以使其变化，使得当催化剂的活化能的边界温度设定为TA℃时，原料的反应速率在（TA-15）℃至TA℃的温度范围内保持恒定。

3. 发明申请

US20110223490A1 NONAQUEOUS ELECTROLYTE SECONDARY BATTERY 审中-公开
标题翻译：非电解电解质二次电池
公开(公告)号：US20110223490A1
公开(公告)日：2011-09-15
申请号：US13042543
申请日：2011-03-08
申请人： Kazushi Andou , Koji Abe , Kazuhiro Miyoshi , Masahide Kondo
发明人： Kazushi Andou , Koji Abe , Kazuhiro Miyoshi , Masahide Kondo
IPC分类号： H01M10/0564 , H01M10/056
CPC分类号： H01M10/0567 , H01M4/364 , H01M4/505 , H01M4/525 , H01M10/052 , H01M10/0569 , H01M2300/0025 , H01M2300/0034 , H01M2300/0037 , H01M2300/004
摘要： In the nonaqueous electrolyte secondary battery, the positive electrode active material is composed of a mixture of a lithium-cobalt composite oxide containing at least both zirconium and magnesium, and a lithium-manganese-nickel composite oxide containing at least both manganese and nickel. The nonaqueous electrolyte includes fluoroethylene carbonate and dimethyl carbonate as a nonaqueous solvent and further includes an additive expressed by General Formula (1), which having a capability to form an SEI surface film, and a higher oxidation resistance than that of VC. Thus, the negative electrode active material is unlikely to react with the organic solvent. Therefore, decomposition of the organic solvent is suppressed. Thus the battery having a long cycling life even when it is charged at a positive electrode charging potential of 4.4 to 4.6 V based on lithium and having a high residual capacity after storage at high temperature in a charged state is provided.
摘要翻译：在非水电解质二次电池中，正极活性物质由至少含有锆和镁两者的锂 - 钴复合氧化物和至少含有锰和镍两者的锂 - 锰 - 镍复合氧化物的混合物构成。非水电解质包括氟代碳酸亚乙酯和作为非水溶剂的碳酸二甲酯，并且还包括具有形成SEI表面膜的能力和比VC更高的抗氧化性的由通式（1）表示的添加剂。因此，负极活性物质不可能与有机溶剂发生反应。因此，有机溶剂的分解被抑制。因此，电池具有长的循环寿命，即使在基于锂的正极充电电位为4.4〜4.6V下充电，并且在充电状态下在高温下保存后具有高剩余容量。

4. 发明申请

US20090221847A1 METHOD FOR PRODUCING UNSATURATED ALDEHYDE AND UNSATURATED CARBOXYLIC ACID 有权
标题翻译：生产不饱和醛和不饱和羧酸的方法
公开(公告)号：US20090221847A1
公开(公告)日：2009-09-03
申请号：US12281694
申请日：2007-03-06
申请人： Masahide Kondo , Seiichi Kawato , Toru Kuroda
发明人： Masahide Kondo , Seiichi Kawato , Toru Kuroda
IPC分类号： C07C61/16 , C07C47/20
CPC分类号： C07C51/252 , B01J23/002 , B01J37/0009 , B01J37/0045 , B01J2523/00 , C07C45/35 , C07C45/37 , C07C51/235 , C07C47/22 , C07C57/04 , B01J2523/15 , B01J2523/27 , B01J2523/53 , B01J2523/54 , B01J2523/68 , B01J2523/842 , B01J2523/845
摘要： Disclosed is a method of a gas-phase catalytic oxidation reaction of propylene, isobutylene, or tertiary butanol with molecular oxygen in the presence of a catalyst to produce a corresponding unsaturated aldehyde and a corresponding unsaturated carboxylic acid, in which the catalyst can be used over a long period of time. Concretely, in the presence of the catalyst containing a complex oxide including molybdenum, bismuth and iron as essential components, at least one factor of a reaction pressure and a molar ratio of molecular oxygen to a raw material is controlled to change in such a way that a rate of reaction of the raw material is kept constant in the temperature range of from (TA-15)° C. to TA° C., when a boundary temperature of the activation energy of the catalyst is set to be TA° C.
摘要翻译：公开了在催化剂存在下丙烯，异丁烯或叔丁醇与分子氧的气相催化氧化反应的方法，以产生相应的不饱和醛和相应的不饱和羧酸，其中可以使用催化剂很长一段时间。具体地说，在含有包含钼，铋和铁作为必要成分的复合氧化物的催化剂的存在下，控制至少一个反应压力因子和分子氧与原料的摩尔比，以使其变化，使得当催化剂的活化能的边界温度设定为TA℃时，原料的反应速率在（TA-15）℃至TA℃的温度范围内保持恒定。

5. 发明申请

US20060158257A1 Semiconductor circuit 审中-公开
标题翻译：半导体电路
公开(公告)号：US20060158257A1
公开(公告)日：2006-07-20
申请号：US10547467
申请日：2004-03-22
申请人： Masahiro Fujimoto , Ryuji Oyama , Masahide Kondo , Hiroshi Oda
发明人： Masahiro Fujimoto , Ryuji Oyama , Masahide Kondo , Hiroshi Oda
IPC分类号： H03F3/68 , H03F3/04
CPC分类号： H03F3/211 , H03F1/30 , H03F3/24
摘要： Second transistors working as temperature-monitoring elements are disposed in the vicinity of the respective first transistors (HBT cells) connected in parallel to amplify an RF signal and at positions where their thermal environments are substantially the same. Each of the second transistors is connected between its collector and its base to thereby constitute a diode through which the current rises as the temperature increases. The collectors of the second transistors are connected with a DC power supply through respective first resistors, and their emitters are grounded through respective second resistors. Further, their bases are connected with the bases of the respective first transistors through respective first inductors.
摘要翻译：作为温度监视元件工作的第二晶体管被设置在并联连接的各个第一晶体管（HBT单元）的附近，以放大RF信号和它们的热环境基本相同的位置。每个第二晶体管连接在其集电极和其基极之间，从而构成二极管，随着温度的升高电流上升。第二晶体管的集电极通过相应的第一电阻器与直流电源连接，并且它们的发射极通过相应的第二电阻器接地。此外，它们的基极通过相应的第一电感器与各个第一晶体管的基极连接。

6. 发明授权

US5440018A Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same 失效
标题翻译：重组人血清白蛋白，其制备方法和含有其的药物制剂
公开(公告)号：US5440018A
公开(公告)日：1995-08-08
申请号：US36387
申请日：1993-03-24
申请人： Takao Ohmura , Akinori Sumi , Wataru Ohtani , Naoto Fuluhata , Kazuya Takeshima , Kaeko Kamide , Munehiro Noda , Masahide Kondo , Syoichi Ishikawa , Kazuhiro Oohara , Kazumasa Yokoyama
发明人： Takao Ohmura , Akinori Sumi , Wataru Ohtani , Naoto Fuluhata , Kazuya Takeshima , Kaeko Kamide , Munehiro Noda , Masahide Kondo , Syoichi Ishikawa , Kazuhiro Oohara , Kazumasa Yokoyama
IPC分类号： A61K38/00 , C07K1/14 , C07K14/765 , C12N15/14 , A61K38/38 , C07K1/16 , C07K1/36
CPC分类号： C07K14/765 , A61K38/00
摘要： Human serum albumin obtained by gene manipulation techniques can be purified by a combination of specified steps in which a culture supernatant obtained from a human serum albumin-producing host is subjected to ultrafiltration, heat treatment, acid treatment and another ultrafiltration, followed by subsequent treatments with a cation exchanger, a hydrophobic chromatography carrier and an anion exchanger, and by salting-out to thereby obtain a pure form of human serum albumin which contains substantially no proteinous and polysaccharide contaminants, which is formulated into a pharmaceutical preparation. This process makes it possible to effeciently purify recombinant human serum albumin and to provide substantially pure human serum albumin which does not contain producer host-related substances and other contaminants and is sufficiently free from coloration.
摘要翻译：通过基因操作技术获得的人血清白蛋白可以通过特定步骤的组合来纯化，其中将得自人血清白蛋白的宿主的培养上清液进行超滤，热处理，酸处理和另一次超滤，然后用阳离子交换剂，疏水性色谱载体和阴离子交换剂，并通过盐析，从而获得纯的形式的人血清白蛋白，其基本上不含有配制成药物制剂的蛋白质和多糖污染物。该方法使得可以有效地纯化重组人血清白蛋白并提供基本上纯的人血清白蛋白，其不含生产者宿主相关物质和其它污染物，并且没有着色。

7. 发明授权

US08865353B2 Nonaqueous electrolyte and lithium cell using the same 有权
标题翻译：非水电解液和锂电池使用相同
公开(公告)号：US08865353B2
公开(公告)日：2014-10-21
申请号：US13057035
申请日：2009-08-04
申请人： Koji Abe , Masahide Kondo
发明人： Koji Abe , Masahide Kondo
IPC分类号： H01M6/18 , H01M6/16 , H01M10/0569 , H01M10/0567 , H01M10/0568 , H01M10/052
CPC分类号： H01M10/0567 , H01M6/166 , H01M6/168 , H01M10/052 , H01M10/0568 , H01M10/0569 , H01M2300/0042 , Y02E60/12 , Y02T10/7011
摘要： A nonaqueous electrolytic solution of an electrolyte salt dissolved in a nonaqueous solvent, containing a hydantoin compound represented by the following general formula (I) in an amount of from 0.01 to 5% by mass of the nonaqueous electrolytic solution, and excellent in battery characteristics such as high-temperature storage property and cycle property. (In the formula, R1 and R2 each represent a methyl group or an ethyl group; R3 and R4 each represent a hydrogen atom, a methyl group or an ethyl group.)
摘要翻译：溶解在非水溶剂中的电解质盐的非水电解液含有由以下通式（I）表示的乙内酰脲化合物，其量为非水电解液的0.01〜5质量％，电池特性优异作为高温储存性能和循环性能。（式中，R 1和R 2各自表示甲基或乙基; R 3和R 4各自表示氢原子，甲基或乙基。）

8. 发明申请

US20120282529A1 NONAQUEOUS ELECTROLYTE AND ELECTROCHEMICAL ELEMENT USING THE SAME 审中-公开
标题翻译：非电解电解质和电化学元素
公开(公告)号：US20120282529A1
公开(公告)日：2012-11-08
申请号：US13522625
申请日：2011-01-18
申请人： Koji Abe , Masahide Kondo
发明人： Koji Abe , Masahide Kondo
IPC分类号： H01M10/056 , H01M10/0567 , H01M10/0525
CPC分类号： H01M10/0569 , H01G9/038 , H01G11/58 , H01G11/60 , H01G11/62 , H01M6/164 , H01M6/168 , H01M10/0567 , H01M2300/0037 , Y02E60/13 , Y02T10/7022
摘要： A nonaqueous electrolytic solution capable of improving the low-temperature cycle properties, which is a nonaqueous electrolytic solution of an electrolyte salt dissolved in a nonaqueous solvent, wherein the nonaqueous solvent contains at least two cyclic carbonates selected from ethylene carbonate, 1,2-butylene carbonate, a cyclic carbonate having a methyl group at least at 4-position of ethylene carbonate, and a cyclic carbonate having a fluorine atom at least at 4-position of ethylene carbonate, and the content of the cyclic carbonate having a methyl group at least at 4-position of ethylene carbonate and/or the cyclic carbonate having a fluorine atom at least at 4-position of ethylene carbonate is from 1 to 40% by volume of the total volume of the nonaqueous solvent, and which contains trimethylene glycol sulfite in an amount of from 0.1 to 5% by mass, and an electrochemical element using the same.
摘要翻译：一种能够提高低温循环性能的非水电解液，其是溶解在非水溶剂中的电解质盐的非水电解液，其中非水溶剂含有至少两种选自碳酸亚乙酯，1,2-亚丁基碳酸酯，具有甲基至少在碳酸亚乙酯的4-位的环状碳酸酯和至少在碳酸亚乙酯的4-位具有氟原子的环状碳酸酯，并且至少具有甲基的环状碳酸酯的含量至少在碳酸亚乙酯的4-位和/或至少在碳酸亚乙酯的4-位具有氟原子的环状碳酸酯为非水溶剂的总体积的1〜40体积％，并且其中含有亚硫酸甘油酯 0.1〜5质量％的量，使用该电化学元素的电化学元素。

9. 发明申请

US20090170696A1 PROCESS FOR PRODUCING CATALYST 有权
标题翻译：生产催化剂的方法
公开(公告)号：US20090170696A1
公开(公告)日：2009-07-02
申请号：US11994654
申请日：2006-07-05
申请人： Masahide Kondo , Masanori Nitta , Hiroyuki Naitou , Toru Kuroda , Seiichi Kawato
发明人： Masahide Kondo , Masanori Nitta , Hiroyuki Naitou , Toru Kuroda , Seiichi Kawato
IPC分类号： B01J23/881
CPC分类号： B01J23/8885 , B01J21/08 , B01J23/002 , B01J23/8876 , B01J35/002 , B01J35/023 , B01J37/0009 , B01J37/0045 , B01J2523/00 , B08B9/08 , C07C45/35 , C07C51/252 , C07C253/18 , C07C47/22 , C07C57/04 , B01J2523/13 , B01J2523/27 , B01J2523/53 , B01J2523/54 , B01J2523/68 , B01J2523/69 , B01J2523/842 , B01J2523/845
摘要： Disclosed is a method for producing a catalyst, in which physical properties of a dried material or a calcined material in a production process of the catalyst are stable and a change in at least one of a catalyst activity and a selectivity to a target product is small and hence reproducibility of the catalyst is excellent. The present invention is a method for producing a catalyst containing molybdenum, bismuth, and iron, which contains the steps of washing a surface of at least one device equipped in an apparatus for the production of catalyst, to which a solid matter adheres, with a basic solution, and producing the catalyst with the apparatus for the production of catalyst thus washed.
摘要翻译：公开了一种催化剂的制造方法，其中，在催化剂的制造方法中，干燥材料或煅烧材料的物理性质稳定，催化剂活性和对目标产物的选择性中的至少一种的变化小催化剂的再现性优异。本发明是一种生产含有钼，铋和铁的催化剂的方法，其包括以下步骤：将装有固体物质的催化剂装置中装备的至少一种装置的表面与碱性溶液，并用生产如此洗涤的催化剂的装置生产催化剂。

10. 发明申请

US20070149809A1 Catalyst for production of unsaturated aldehyde and unsaturated carboxylic acid, method for producing same, and method for producing unsaturated aldehyde and unsaturated carboxylic acid 有权
标题翻译：用于生产不饱和醛和不饱和羧酸的催化剂，其制备方法，以及不饱和醛和不饱和羧酸的制备方法
公开(公告)号：US20070149809A1
公开(公告)日：2007-06-28
申请号：US10582859
申请日：2004-12-09
申请人： Masahide Kondo , Hiroyuki Naitou , Toru Kuroda
发明人： Masahide Kondo , Hiroyuki Naitou , Toru Kuroda
IPC分类号： C07C51/16 , B01J21/00 , C07C45/28
CPC分类号： C07C45/35 , B01J23/002 , B01J23/8876 , B01J23/8885 , B01J37/0009 , B01J37/0045 , B01J2523/00 , C07C45/32 , C07C45/37 , C07C51/252 , C07C47/22 , C07C57/04 , B01J2523/15 , B01J2523/44 , B01J2523/51 , B01J2523/53 , B01J2523/54 , B01J2523/68 , B01J2523/69 , B01J2523/842 , B01J2523/845 , B01J2523/847 , B01J2523/13 , B01J2523/48
摘要： A catalyst for use in producing an unsaturated aldehyde and an unsaturated carboxylic acid which is excellent in catalyst activity and selectivity to the unsaturated aldehyde and the unsaturated carboxylic acid, a method for producing such a catalyst and a method for producing an unsaturated aldehyde and an unsaturated carboxylic acid by using such a catalyst are provided. A method for producing a catalyst containing at least molybdenum, bismuth and iron for use in producing an unsaturated aldehyde and an unsaturated carboxylic acid through gas-phase catalytic oxidation of propylene, isobutylene, tertiary butyl alcohol or methyl tertiary butyl ether with molecular oxygen comprises the steps of kneading particles containing catalyst components, an organic binder and a liquid and extrusion molding the resultant kneaded mixture, the organic binder containing at least a high-viscosity organic binder having a viscosity (of its 1% water solution or dispersion at 20° C.) of from 5,000 mPa.s to 25,000 mPa.s and a low-viscosity organic binder having a viscosity (of its 1% water solution or dispersion at 20° C.) of from 10 mPa.s to less than 5,000 mPa.s.
摘要翻译：用于制备对不饱和醛和不饱和羧酸的催化剂活性和选择性优异的不饱和醛和不饱和羧酸的催化剂，这种催化剂的制备方法以及不饱和醛和不饱和醛的制备方法提供了使用这种催化剂的羧酸。通过丙烯，异丁烯，叔丁醇或甲基叔丁基醚与分子氧的气相催化氧化制备用于制备不饱和醛和不饱和羧酸的至少含有钼，铋和铁的催化剂的方法包括捏合含有催化剂组分的颗粒，有机粘合剂和液体并挤出成型所得捏合混合物的步骤，所述有机粘合剂含有至少具有粘度（其1％水溶液或分散体在20℃）的高粘度有机粘合剂。）为5,000mPa.s至25,000mPa.s，粘度（其1％水溶液或20℃下的分散体为20℃）的低粘度有机粘合剂为10mPa.s至小于5,000mPa。 s。

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