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1. 发明授权

US07833792B2 Test strip measuring method 有权
标题翻译：试片测量方法
公开(公告)号：US07833792B2
公开(公告)日：2010-11-16
申请号：US11119704
申请日：2005-05-03
申请人： Masaaki Mori , Masao Ninomiya , Tomokuni Inoue , Eiji Ikegami , Akira Tanaka
发明人： Masaaki Mori , Masao Ninomiya , Tomokuni Inoue , Eiji Ikegami , Akira Tanaka
IPC分类号： G01N33/48
CPC分类号： G01N21/8483 , Y10T436/112499 , Y10T436/115831
摘要： In a test strip measuring method in which a coloration measurement is conducted while a test strip (4) is being moved, there are detected the optical characteristics R of the ground of a test strip and the optical characteristics T of a test line (4b) which has appeared on the test strip, and the test strip is judged based on the difference or ratio between R and T. Even though the ground of the test strip presents variations in optical characteristics, and even though there are variations among samples or among test strips, such variations can be absorbed, thus assuring an accurate judgment.
摘要翻译：在测试条（4）移动时进行着色测量的测试条测量方法中，检测测试条的接地的光学特性R和测试线（4b）的光学特性T，其出现在测试条上，并且基于R和T之间的差异或比例来判断测试条。即使测试条的地面呈现光学特性的变化，并且即使样品之间或测试中存在变化可以吸收这种变化，从而确保准确的判断。

2. 发明申请

US20050191210A1 Test strip measuring method and device 有权
标题翻译：测试条测量方法和装置
公开(公告)号：US20050191210A1
公开(公告)日：2005-09-01
申请号：US11119704
申请日：2005-05-03
申请人： Masaaki Mori , Masao Ninomiya , Tomokuni Inoue , Eiji Ikegami , Akira Tanaka
发明人： Masaaki Mori , Masao Ninomiya , Tomokuni Inoue , Eiji Ikegami , Akira Tanaka
IPC分类号： G01N31/22 , G01N21/78 , G01N21/86 , G01N33/52
CPC分类号： G01N21/8483 , Y10T436/112499 , Y10T436/115831
摘要： In a test strip measuring method in which a coloration measurement is conducted while a test strip (4) is being moved, there are detected the optical characteristics R of the ground of a test strip and the optical characteristics T of a test line (4b) which has appeared on the test strip, and the test strip is judged based on the difference or ratio between R and T. Even though the ground of the test strip presents variations in optical characteristics, and even though there are variations among samples or among test strips, such variations can be absorbed, thus assuring an accurate judgment.
摘要翻译：在测试条（4）移动时进行着色测量的测试条测量方法中，检测测试条的接地的光学特性R和测试线的光学特性T（4 b ），并且基于R和T之间的差异或比例来判断测试条。即使测试条的地面呈现光学特性的变化，并且即使在样品之间或之间存在差异测试条可以吸收这种变化，从而确保准确的判断。

3. 发明授权

US5964712A Apparatus and breathing bag for spectrometrically measuring isotopic gas 失效
标题翻译：用于光谱测量同位素气体的仪器和呼吸袋
公开(公告)号：US5964712A
公开(公告)日：1999-10-12
申请号：US849351
申请日：1997-06-06
申请人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
发明人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
IPC分类号： A61B5/00 , A61B5/08 , A61B5/083 , A61B5/097 , A61B10/00 , G01N1/22 , G01N21/03 , G01N21/11 , G01N21/25 , G01N21/27 , G01N21/31 , G01N21/35 , G01N21/59 , G01N33/00 , G01N33/497 , G01N35/08 , B01L3/00
CPC分类号： G01N21/3504 , A61B10/00 , A61B5/097 , G01N21/0332 , G01N21/11 , G01N21/274 , G01N21/314 , A61B2010/0087 , A61B5/0059 , A61B5/0836 , G01N33/0006 , G01N33/497
摘要： A correction curve (FIG. 19) is prepared by plotting .sup.12 CO.sub.2 concentrations and .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratios which are determined on the basis of a calibration curve and .sup.13 CO.sub.2 and .sup.12 CO.sub.2 absorbances of gaseous samples having the same .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio but known different .sup.12 CO.sub.2 concentrations. A gaseous test sample containing .sup.13 CO.sub.2 and .sup.12 CO.sub.2 as component gases is introduced into a cell, and spectrometrically measured. A .sup.12 CO.sub.2 concentration of the gaseous test sample is determined by way of the spectrometric measurement. A concentration ratio correction value is obtained on the basis of the correction curve and the .sup.12 CO.sub.2 concentration of the gaseous test sample thus determined. A measured .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio is divided by the concentration ratio correction value thus obtained for correction of the .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio. Thus, the measurement accuracy of the concentration ratios of the component gases can be improved. A breath sampling bag and gas measuring system is also disclosed where each is configured such that breath inlets of the gas measuring apparatus are prevented from being respectively connected to the wrong breath introduction pipes of the breath sampling bag.
摘要翻译： PCT No.PCT / JP96 / 02876 Sec。 371日期：1997年6月6日 102（e）日期1996年6月6日PCT提交1996年10月2日PCT公布。公开号WO97 / 14029 日期1997年04月17日通过绘制12CO2浓度和13CO2 / 12CO2浓度比，制备校正曲线（图19），其基于校准曲线确定，并且具有13CO 2 / 12CO 2浓度的气态样品的13CO 2和12 CO 2吸光度比例但已知不同的12CO2浓度。将含有作为组分气体的13CO 2和12 CO 2的气态测试样品引入到电池中，并进行光谱测量。通过光谱测量法测定气态测试样品的12CO2浓度。基于如此确定的气体试样的校正曲线和12CO 2浓度获得浓度比校正值。测量的13CO 2 / 12CO 2浓度比除以由此获得的用于校正13CO 2 / 12CO 2浓度比的浓度比校正值。因此，能够提高成分气体的浓度比的测定精度。还公开了一种呼吸取样袋和气体测量系统，其中每个呼气采样袋和气体测量系统被配置为使得气体测量装置的呼吸入口被防止分别连接到呼吸取样袋的错误的呼吸导管。

4. 发明授权

US06274870B1 Method for spectrometrically measuring isotopic gas and apparatus thereof 有权
标题翻译：光谱测量同位素气体的方法及其装置
公开(公告)号：US06274870B1
公开(公告)日：2001-08-14
申请号：US09303427
申请日：1999-05-03
申请人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
发明人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
IPC分类号： G01N2135
CPC分类号： G01N21/3504 , A61B5/0059 , A61B5/0836 , A61B5/097 , A61B10/00 , A61B2010/0087 , G01N21/0332 , G01N21/11 , G01N21/274 , G01N21/314 , G01N33/0006 , G01N33/497
摘要： A correction curve (FIG. 19) is prepared by plotting 12CO2 concentrations and 13CO2/12CO2 concentration ratios which are determined on the basis of a calibration curve and 13CO2 and 12CO2 absorbances of gaseous samples having the same 13CO2/12CO2 concentration ratio but known different 12CO2 concentrations. A gaseous test sample containing 13CO2 and 12CO2 as component gases is introduced into a cell, and spectrometrically measured. A 12CO2 concentration of the gaseous test sample is determined by way of the spectrometric measurement. A concentration ratio correction value is obtained on the basis of the correction curve and the 12CO2 concentration of the gaseous test sample thus determined. A measured 13CO2/12CO2 concentration ratio is divided by the concentration ratio correction value thus obtained for correction of the 13CO2/12CO2 concentration ratio. Thus, the measurement accuracy of the concentration ratios of the component gases can be improved.
摘要翻译：通过绘制12CO2浓度和13CO2 / 12CO2浓度比，通过绘制12CO2浓度和13CO2 / 12CO2浓度比来制备校正曲线（13CO2 / 12CO2浓度比），这些浓度比是根据13CO2 / 12CO2浓度比相同但已知不同12CO2的气态样品的校正曲线和13CO2和12CO2吸光度确定的浓度将含有作为组分气体的13CO 2和12 CO 2的气态测试样品引入到电池中，并进行光谱测量。通过光谱测量法测定气态测试样品的12CO2浓度。基于如此确定的气体试样的校正曲线和12CO 2浓度获得浓度比校正值。测量的13CO 2 / 12CO 2浓度比除以由此获得的用于校正13CO 2 / 12CO 2浓度比的浓度比校正值。因此，能够提高成分气体的浓度比的测定精度。

5. 发明授权

US09591992B2 Method of exhaled gas measurement and analysis and apparatus therefor 有权
标题翻译：呼出气体测量和分析方法及其设备
公开(公告)号：US09591992B2
公开(公告)日：2017-03-14
申请号：US13565437
申请日：2012-08-02
申请人： Yasuhiro Kubo , Masaaki Mori
发明人： Yasuhiro Kubo , Masaaki Mori
IPC分类号： A61B5/08 , A61B5/083 , G01N1/22 , G01N21/3504 , G01N33/497 , A61B5/097
CPC分类号： A61B5/0836 , A61B5/097 , G01N1/22 , G01N21/3504 , G01N33/497
摘要： An exhalation collected in a breath bag capable of expanding and contracting is sucked into a gas inlet vessel 21 with a given volume (Va), and then the gas inlet vessel 21 is communicated by means of valve V2 with a cell 11 that is maintained at an atmospheric pressure by being pre-filled with a sample gas or reference gas. After the communication, the gas pressure is measured by a pressure sensor 16 attached to the cell 11. Whether the exhalation collected in the breath bag is below a given amount or not can be accurately judged.
摘要翻译：将收集在能够膨胀和收缩的呼吸袋中的呼气吸入具有给定体积（Va）的气体入口容器21中，然后气体入口容器21通过阀V2与保持在通过预先填充有样品气体或参考气体的大气压力。在通信之后，气体压力通过安装在电池单元11上的压力传感器16来测量。可以准确地判断呼吸袋中收集的呼气是否低于给定量。

6. 发明授权

US08057990B2 Screening method 失效
标题翻译：筛选方法
公开(公告)号：US08057990B2
公开(公告)日：2011-11-15
申请号：US11885781
申请日：2006-03-07
申请人： Masaaki Mori , Kimiko Kanehashi
发明人： Masaaki Mori , Kimiko Kanehashi
IPC分类号： G01N33/53 , C07D219/00 , C07D219/08 , C07D219/10 , C07K14/00
CPC分类号： A61K31/473 , G01N2500/02
摘要： The present invention provides a medicament for preventing/treating cancer, comprising a tacrine compound, or a compound promoting the binding between the tacrine compound and a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1.
摘要翻译：本发明提供了用于预防/治疗癌症的药物，其包含他克林化合物或促进他克林化合物与包含与SEQ ID NO所示氨基酸序列相同或基本相同的氨基酸序列的蛋白质之间的结合的化合物：1。

7. 发明申请

US20100269464A1 FILTER MEDIUM AND METHOD OF MANUFACTURING THE SAME AND FILTER UNIT 有权
标题翻译：过滤介质及其制造方法和过滤器单元
公开(公告)号：US20100269464A1
公开(公告)日：2010-10-28
申请号：US12742625
申请日：2008-11-11
申请人： Masaaki Mori , Masatoshi Suzuki
发明人： Masaaki Mori , Masatoshi Suzuki
IPC分类号： B01D39/20 , B32B37/04
CPC分类号： B01D39/1692 , B01D69/12 , B01D71/36 , B01D2239/0654
摘要： Provided is a filter medium including a porous polytetrafluoroethylene (PTFE) membrane and a gas-permeable supporting member that are integrated to ensure sufficient stiffness, having excellent gas permeability, and providing excellent bonding between respective layers included in the filter medium. The gas-permeable supporting member includes: a substrate having gas-permeability; and a fiber layer that is placed on the substrate so as to be in contact with the porous PTFE membrane. The gas-permeable supporting member has a structure in which fibers of the fiber layer enter into the substrate and are entangled with the substrate so that the fiber layer is bonded to the substrate. The fiber layer contains polyolefin-containing fibers that are bonded to the porous membrane.
摘要翻译：提供了一种过滤介质，其包括多孔聚四氟乙烯（PTFE）膜和气体可渗透的支撑构件，其一体化以确保足够的刚度，具有优异的气体渗透性，并且在包含在过滤介质中的各个层之间提供优异的粘合。透气性支撑构件包括：具有透气性的基板; 以及放置在基板上以与多孔PTFE膜接触的纤维层。透气性支撑构件具有纤维层的纤维进入基板并与基板缠结的结构，使得纤维层与基板结合。纤维层含有与多孔膜结合的含有聚烯烃的纤维。

8. 发明申请

US20090306527A1 Method of Exhaled Gas Measurement and Analysis and Apparatus Therefor 审中-公开
标题翻译：呼气测量与分析方法及其设备
公开(公告)号：US20090306527A1
公开(公告)日：2009-12-10
申请号：US12223539
申请日：2007-01-31
申请人： Yasuhiro Kubo , Masaaki Mori
发明人： Yasuhiro Kubo , Masaaki Mori
IPC分类号： A61B5/097
CPC分类号： A61B5/0836 , A61B5/097 , G01N1/22 , G01N21/3504 , G01N33/497
摘要： An exhalation collected in a breath bag capable of expanding and contracting is sucked into a gas inlet vessel 21 with a given volume (Va), and then the gas inlet vessel 21 is communicated by means of valve V2 with a cell 11 that is maintained at an atmospheric pressure by being pre-filled with a sample gas or reference gas. After the communication, the gas pressure is measured by a pressure sensor 16 attached to the cell 11. Whether the exhalation collected in the breath bag is below a given amount or not can be accurately judged.
摘要翻译：将收集在能够膨胀和收缩的呼吸袋中的呼气吸入具有给定体积（Va）的气体入口容器21中，然后气体入口容器21通过阀V2与保持在通过预先填充有样品气体或参考气体的大气压力。在通信之后，气体压力通过安装在电池单元11上的压力传感器16来测量。可以准确地判断呼吸袋中收集的呼气是否低于给定量。

9. 发明授权

US07323541B2 Polypeptide DNA thereof and use of the same 失效
标题翻译：其多肽DNA及其用途
公开(公告)号：US07323541B2
公开(公告)日：2008-01-29
申请号：US10489537
申请日：2002-09-13
申请人： Masaaki Mori , Kozo Hayashi , Hiroyuki Miya , Shuji Sato , Chieko Kitada , Hirokazu Matsumoto , Toshimi Nagi , Yukio Shimomura
发明人： Masaaki Mori , Kozo Hayashi , Hiroyuki Miya , Shuji Sato , Chieko Kitada , Hirokazu Matsumoto , Toshimi Nagi , Yukio Shimomura
IPC分类号： A61K38/04
CPC分类号： C07K14/705 , A61K38/00 , A61K48/00
摘要： The present invention aims at providing a novel polypeptide, a receptor, a DNA thereof, and the like. Specifically, the present invention provides a polypeptide having a binding ability to the protein represented by SEQ ID NO: 1 or SEQ ID NO: 3, or its amide, its ester or its salt, a polynucleotide encoding the polypeptide, an antisense polynucleotide or an antibody to the polypeptide, a screening of agent for prevention and/or treatment of cancer, obesity, etc., which comprises using the above, and the like.The polypeptide, receptor, polynucleotide, antisense polynucleotide, antibody and the like are useful for an agent of prevention and/or treatment of cancer, obesity and the like. Further, they are useful for a screening of an agent for prevention and/or treatment of cancer, obesity and the like.
摘要翻译：本发明的目的在于提供新的多肽，受体及其DNA等。具体地说，本发明提供了具有与SEQ ID NO：1或SEQ ID NO：3所代表的蛋白结合能力的多肽或其酰胺，其酯或其盐，编码多肽的多核苷酸，反义多核苷酸或对多肽的抗体，筛选用于预防和/或治疗癌症，肥胖症等的药剂，其包括使用上述方法等。多肽，受体，多核苷酸，反义多核苷酸，抗体等可用于预防和/或治疗癌症，肥胖症等。此外，它们可用于筛选用于预防和/或治疗癌症，肥胖症等的药剂。

10. 发明授权

US07273710B2 Method for screening MCH receptor antagonist/agonist 失效
标题翻译：筛选MCH受体拮抗剂/激动剂的方法
公开(公告)号：US07273710B2
公开(公告)日：2007-09-25
申请号：US10332082
申请日：2001-07-04
申请人： Masaaki Mori , Yukio Shimomura , Mioko Harada , Tsukasa Sugo , Yasushi Shintani
发明人： Masaaki Mori , Yukio Shimomura , Mioko Harada , Tsukasa Sugo , Yasushi Shintani
IPC分类号： C07K11/02 , C07K14/705 , G01N33/566
CPC分类号： G01N33/566 , A61K38/00 , G01N33/74 , G01N2333/726
摘要： The present invention relates to a screening method for a compound or a salt thereof that alters the binding property of MCH or a salt thereof to SLT or a salt thereof, or a partial peptide thereof, an amide or an ester thereof, or a salt thereof, characterized by using MCH, a derivative or a salt thereof and SLT or a salt thereof, or a partial peptide thereof, an amide or an ester thereof, or a salt thereof. The screening method of the present invention is useful for screening an SLT agonist, which can be used as an agent for promoting appetite (eating), and an SLT antagonist, which can be used as a prophylactic and/or therapeutic agent for obesity.
摘要翻译：本发明涉及一种化合物或其盐的筛选方法，其改变MCH或其盐与SLT或其盐或其部分肽，酰胺或其酯或其盐的结合性其特征在于使用MCH，其衍生物或其盐，SLT或其盐或其部分肽，酰胺或其酯或其盐。本发明的筛选方法可用于筛选可用作促进食欲的药物（进食）的SLT激动剂和可用作肥胖症的预防和/或治疗剂的SLT拮抗剂。

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