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    • 1. 发明授权
    • Catheter for target specific drug delivery
    • 目标特异性药物输送导管
    • US07153292B2
    • 2006-12-26
    • US10828688
    • 2004-04-21
    • Mary M MorrisDouglas Owen Hankner
    • Mary M MorrisDouglas Owen Hankner
    • A61M5/00A61M25/00
    • A61M5/14276A61M5/16877A61M25/0069A61M25/007A61M27/006A61M39/02A61M2025/0057
    • A medical catheter comprising a proximal end having an opening for fluid containing a therapeutic drug, a distal end, the distal end defining at least one opening, and a porous portion covering the opening defined by the distal end. In one embodiment, the medical catheter comprises a proximal end having an opening for fluid containing a therapeutic drug, at least two distal ends, the proximal end connected to the two distal ends with a connector, the distal ends each defining at least one opening, a diffuser covering the opening of each distal end, and a separate restrictor downstream of the connector and upstream of each distal end to provide substantially equal flow through each distal end. An additional restrictor can also be placed upstream of the connector. In another embodiment, a combination diffuser and restrictor covers the opening of each distal end. In one embodiment, the diffuser can define tubes that extend from the inside surface of the diffuser to the outside surface of the diffuser, to permit more equal drug flow through the tubes defined therein.
    • 一种医用导管,包括具有用于含有治疗药物的流体的开口的近端,远端,限定至少一个开口的远端以及覆盖由远端限定的开口的多孔部分。 在一个实施例中,医疗导管包括近端,其具有用于含有治疗药物的流体的开口,至少两个远端,所述近端与两个远端连接有连接器,所述远端各限定至少一个开口, 覆盖每个远端的开口的扩散器,以及在连接器的下游和每个远端的上游的单独的限制器,以提供通过每个远端的基本相等的流动。 另外还可以在连接器的上游设置一个限流器。 在另一个实施例中,组合扩散器和限流器覆盖每个远端的开口。 在一个实施例中,扩散器可以限定从扩散器的内表面延伸到扩散器的外表面的管,以允许更均等的药物流过其中限定的管。
    • 2. 发明授权
    • Catheter for target specific drug delivery
    • 目标特异性药物输送导管
    • US06945969B1
    • 2005-09-20
    • US09625751
    • 2000-07-26
    • Mary M. MorrisDouglas Owen Hankner
    • Mary M. MorrisDouglas Owen Hankner
    • A61M5/142A61M5/168A61M25/00A61M27/00A61M39/02A61M31/00A61M5/00A61M25/16A61M25/18
    • A61M5/14276A61M5/16877A61M25/0069A61M25/007A61M27/006A61M39/02A61M2025/0057
    • A medical catheter comprising a proximal end having an opening for fluid containing a therapeutic drug, a distal end, the distal end defining at least one opening, and a porous portion covering the opening defined by the distal end. In one embodiment, the medical catheter comprises a proximal end having an opening for fluid containing a therapeutic drug, at least two distal ends, the proximal end connected to the two distal ends with a connector, the distal ends each defining at least one opening, a diffuser covering the opening of each distal end, and a separate restrictor downstream of the connector and upstream of each distal end to provide substantially equal flow through each distal end. An additional restrictor can also be placed upstream of the connector. In another embodiment, a combination diffuser and restrictor covers the opening of each distal end. In one embodiment, the diffuser can define tubes that extend from the inside surface of the diffuser to the outside surface of the diffuser, to permit more equal drug flow through the tubes defined therein.
    • 一种医用导管,包括具有用于含有治疗药物的流体的开口的近端,远端,限定至少一个开口的远端以及覆盖由远端限定的开口的多孔部分。 在一个实施例中,医疗导管包括近端,其具有用于含有治疗药物的流体的开口,至少两个远端,所述近端与两个远端连接有连接器,所述远端各限定至少一个开口, 覆盖每个远端的开口的扩散器,以及在连接器的下游和每个远端的上游的单独的限制器,以提供通过每个远端的基本相等的流动。 另外还可以在连接器的上游设置一个限流器。 在另一个实施例中,组合扩散器和限流器覆盖每个远端的开口。 在一个实施例中,扩散器可以限定从扩散器的内表面延伸到扩散器的外表面的管,以允许更均等的药物流过其中限定的管。
    • 3. 发明授权
    • Catheter for target specific drug delivery
    • 目标特异性药物输送导管
    • US06551290B1
    • 2003-04-22
    • US09540444
    • 2000-03-31
    • Dennis D. ElsberryChris ChristiansenMary M. MorrisDouglas Owen HanknerRobert Cushing Hamlen
    • Dennis D. ElsberryChris ChristiansenMary M. MorrisDouglas Owen HanknerRobert Cushing Hamlen
    • A61M2500
    • A61M25/0069A61M5/14276A61M27/006A61M2025/0057
    • A medical catheter comprising a proximal end having an opening for fluid containing a therapeutic drug, a distal end, the distal end defining at least one opening, and a porous portion covering the opening defined by the distal end. In one embodiment, the medical catheter comprises a proximal end having an opening for fluid containing a therapeutic drug, at least two distal ends. the proximal end connected to the two distal ends with a connector, the distal ends each defining at least, one opening, a diffuser covering the opening of each distal end, and a separate restrictor downstream of the connector and upstream of each distal end to provide substantially equal flow through each distal end. An additional restrictor can also be placed upstream of the connector. In another embodiment, a combination diffuser and restrictor covers the opening of each distal end.
    • 一种医疗导管,其包括具有用于含有治疗药物的流体的开口的近端,远端,限定至少一个开口的远端以及覆盖由远端限定的开口的多孔部分。 在一个实施例中,医疗导管包括近端,其具有用于含有治疗药物的流体的开口,至少两个远端。 所述近端与连接器连接到所述两个远端,所述远端各限定至少一个开口,覆盖每个远端的开口的扩散器,以及在所述连接器的下游和每个远端上游的单独限制器,以提供 基本相等的流经每个远端。 另外还可以在连接器的上游设置一个限流器。 在另一个实施例中,组合扩散器和限流器覆盖每个远端的开口。