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1. 发明授权

US5695979A Inhibition of reverse transcriptase by phosphorodithioates 失效
标题翻译：通过二硫代磷酸酯抑制逆转录酶
公开(公告)号：US5695979A
公开(公告)日：1997-12-09
申请号：US411474
申请日：1995-03-28
申请人： Marvin H. Caruthers , William S. Marshall , Wolfgang Brill , John Nielsen
发明人： Marvin H. Caruthers , William S. Marshall , Wolfgang Brill , John Nielsen
IPC分类号： C07H19/10 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04 , C12N9/99 , C12N5/10 , C12Q1/68
CPC分类号： C07H19/10 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
摘要： The present invention describes a method for the inhibition of reverse transcriptase by contacting said reverse transcriptase with oligonucleotides having have at least one phosphorodithioate internucleotide linkage of the formula ##STR1## within the phosphorus backbone of the oligonucleotide.
摘要翻译：本发明描述了通过使所述逆转录酶与寡核苷酸的磷骨架中具有式“IMAGE”的至少一个二硫代磷酸核苷酸间键的寡核苷酸接触来抑制逆转录酶的方法。

2. 发明授权

US5453496A Polynucleotide phosphorodithioate 失效
标题翻译：多核苷酸二硫代磷酸酯
公开(公告)号：US5453496A
公开(公告)日：1995-09-26
申请号：US138140
申请日：1993-10-15
申请人： Marvin H. Caruthers , William S. Marshall , Wolfgang Brill , John Nielsen
发明人： Marvin H. Caruthers , William S. Marshall , Wolfgang Brill , John Nielsen
IPC分类号： C07H19/10 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
CPC分类号： C07H19/10 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
摘要： Oligonucleotides having at least one phosphorodithioate internucleotide linkage. Phosphorodithioate oligonucleotides exhibit stronger antiviral activity than the corresponding phoshorothioate derivatives.
摘要翻译：具有至少一个二硫代磷酸核苷酸核苷酸键的寡核苷酸。磷酸二核苷酸寡核苷酸表现出比相应的硫代硫酸酯衍生物更强的抗病毒活性。

3. 发明授权

US5218103A Nucleoside thiophosphoramidites 失效
标题翻译：核苷硫代亚磷酰胺
公开(公告)号：US5218103A
公开(公告)日：1993-06-08
申请号：US643381
申请日：1991-01-22
申请人： Marvin H. Caruthers , Yun-Xi Ma , Eric K. Yau , John Nielsen , Wolfgang Brill
发明人： Marvin H. Caruthers , Yun-Xi Ma , Eric K. Yau , John Nielsen , Wolfgang Brill
IPC分类号： C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
CPC分类号： C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
摘要： The present invention relates to new and useful nucleside thiophosphoramidite, polynucleotide dithioate phosphoramidite and polynucleotide phosphorothioamidate phosphoramidite compounds as well as the process whereby these compounds can be used for synthesizing new monoucleotides and polynucleotides having phosphorodithioate, phosphorothioamidate, phosphorothiotriesters and phosphorothioate internucleotide linkages.
摘要翻译：本发明涉及新的和有用的核苷酸硫代亚磷酰胺，二硫代亚磷酸多核苷酸和多核苷酸硫代酰胺酯亚磷酰胺化合物，以及这些化合物可用于合成新的二核苷酸和具有二硫代磷酸酯，硫代酰胺酯，硫代磷酸酯和硫代磷酸酯核苷酸间键的多核苷酸的方法。

4. 发明授权

US5602244A Polynucleotide phosphorodithioate compounds 失效
标题翻译：多核苷酸二硫代磷酸酯化合物
公开(公告)号：US5602244A
公开(公告)日：1997-02-11
申请号：US436714
申请日：1995-05-08
申请人： Marvin H. Caruthers , Wolfgang K.-D. Brill , Eric Yau , Michael Ma , John Nielsen
发明人： Marvin H. Caruthers , Wolfgang K.-D. Brill , Eric Yau , Michael Ma , John Nielsen
IPC分类号： C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
CPC分类号： C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
摘要： Dinucleoside phosphorodithioate phosphoramidite precursors useful in the synthesis of oligonucleotide phosphorodithioate which can be used as antisense inhibitors of translation.
摘要翻译：用于合成寡核苷酸二硫代磷酸酯的二核苷酸二硫代磷酸亚磷酸酯前体，其可用作翻译的反义抑制剂。

5. 发明授权

US5684148A Nucleoside thiophosphoramidites 失效
标题翻译：核苷硫代亚磷酰胺
公开(公告)号：US5684148A
公开(公告)日：1997-11-04
申请号：US442705
申请日：1995-05-17
申请人： Marvin H. Caruthers , Wolfgang K. D. Brill , Eric Yau , Michael Ma , John Nielsen
发明人： Marvin H. Caruthers , Wolfgang K. D. Brill , Eric Yau , Michael Ma , John Nielsen
IPC分类号： C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
CPC分类号： C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
摘要： The present invention relates to new and useful nucleoside thiophosphoroamidites and polynucleotide phosphorodithioate compounds as well as the processes whereby these compounds may be used for synthesizing new mononucleotides and polynucleotides having phosphorothioate and phosphorodithioate internucleotide linkages.
摘要翻译：本发明涉及新的和有用的核苷硫代亚磷酰胺和多核苷酸二硫代磷酸酯化合物以及这些化合物可用于合成新的单核苷酸和具有硫代磷酸酯和二硫代磷酸酯核苷酸间键的多核苷酸的方法。

6. 发明授权

US5750666A Polynucleotide phosphorodithioate compounds 失效
标题翻译：多核苷酸二硫代磷酸酯化合物
公开(公告)号：US5750666A
公开(公告)日：1998-05-12
申请号：US332829
申请日：1994-10-31
申请人： Marvin H. Caruthers , Wolfgang K.-D Brill , Eric Yau , Michael Ma , John Nielsen
发明人： Marvin H. Caruthers , Wolfgang K.-D Brill , Eric Yau , Michael Ma , John Nielsen
IPC分类号： C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04 , C12N5/10 , C12N9/99 , C12Q1/68
CPC分类号： C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04
摘要： The present invention relates to new and useful nucleoside thiophosphoroamidites and polynucleotide phosphorodithioate compounds as well as the processes whereby these compounds may be used for synthesizing new mononucleotides and polynucleotides having phosphorothioate and phosphorodithioate internucleotide linkages.
摘要翻译：本发明涉及新的和有用的核苷硫代亚磷酰胺和多核苷酸二硫代磷酸酯化合物以及这些化合物可用于合成新的单核苷酸和具有硫代磷酸酯和二硫代磷酸酯核苷酸间键的多核苷酸的方法。

7. 发明授权

US08509790B2 Multi-speed mesh networks 有权
标题翻译：多速网状网络
公开(公告)号：US08509790B2
公开(公告)日：2013-08-13
申请号：US11425917
申请日：2006-06-22
申请人： Tommas Jess Christensen , Jacob Midtgaard , Didier Clement , John Nielsen , Morten Vested Olesen , Olfert Paul Paulsen , Rasmus Glarborg Jensen
发明人： Tommas Jess Christensen , Jacob Midtgaard , Didier Clement , John Nielsen , Morten Vested Olesen , Olfert Paul Paulsen , Rasmus Glarborg Jensen
IPC分类号： H04W72/00
CPC分类号： H04L29/06027 , H04L1/189 , H04L63/0853 , H04L65/607 , H04L2001/0093 , H04W28/22 , H04W92/02
摘要： In embodiments of the present invention improved capabilities are described for a communications facility that is adapted to communicate with at least one other mesh network node at a communication speed selected from a plurality of communication speeds.
摘要翻译：在本发明的实施例中，针对适于以从多个通信速度选择的通信速度与至少一个其他网状网络节点进行通信的通信设施来描述改进的能力。

8. 发明授权

US08340588B2 Handheld synthetic antenna array 失效
标题翻译：手持式合成天线阵列
公开(公告)号：US08340588B2
公开(公告)日：2012-12-25
申请号：US12585605
申请日：2009-09-18
申请人： John Nielsen , Gerard Lachapelle , Ali Broumandan
发明人： John Nielsen , Gerard Lachapelle , Ali Broumandan
IPC分类号： H04B17/00
CPC分类号： H04B7/0891 , H04B7/028 , H04B7/086
摘要： A system for estimating parameters of an incoming signal is provided. At least one antenna is coupled to at least one suitable receiver. The antenna(s) are spatially translated in an arbitrary trajectory. As the antenna(s) is being spatially translated, a data processing means samples the incoming signal at set intervals based on a clock signal provided by a system clock. By sampling the incoming signal at different times at different spatial locations on the arbitrary trajectory, the system acts as a synthetic antenna array. The different samplings of the incoming signal at different times and positions provide signal diversity gain as well as different readings which can be used to estimate and/or calculate various parameters of the incoming signal. The different samplings can be used to detect the incoming signal, estimate its angle of arrival, estimate its time of arrival, as well as other parameters.
摘要翻译：提供了一种用于估计输入信号的参数的系统。至少一个天线耦合到至少一个合适的接收机。天线在任意轨迹上空间转换。当天线被空间转换时，数据处理装置基于由系统时钟提供的时钟信号以设定的时间间隔对输入信号进行采样。通过在任意轨迹上的不同空间位置的不同时间采样输入信号，该系统充当合成天线阵列。在不同时间和位置处的输入信号的不同采样提供信号分集增益以及可用于估计和/或计算输入信号的各种参数的不同读数。不同的采样可用于检测输入信号，估计其到达角度，估计其到达时间以及其他参数。

9. 发明申请

US20110070857A1 SIGNAL DETECTION IN FADING ENVIRONMENTS 失效
标题翻译：衰落环境中的信号检测
公开(公告)号：US20110070857A1
公开(公告)日：2011-03-24
申请号：US12884360
申请日：2010-09-17
申请人： John Nielsen , Gerard Lachapelle , Ali Broumandan
发明人： John Nielsen , Gerard Lachapelle , Ali Broumandan
IPC分类号： H04B1/10
CPC分类号： H04L25/0204 , H04B7/084 , H04L25/03012
摘要： Systems and methods related to the detection of incoming wireless signals. An antenna array is synthesized by having a single antenna, coupled to a receiver, spatially translated along an arbitrary trajectory. As the antenna is being spatially translated, a data processing means samples the incoming signal based on a clock signal provided by a system clock. By sampling the incoming signal at different times at different spatial locations on the arbitrary trajectory, the system acts as a synthetic antenna array. The different samplings of the incoming signal at different times and positions provide signal diversity gain as well as different readings which can be used to detect an incoming signal. The invention is applicable to detecting a wireless communications signal or a GNSS signal under various conditions. The system may include at least one sensor which can provide data for use in calculating data related to the arbitrary trajectory.
摘要翻译：与传入无线信号的检测相关的系统和方法。通过具有耦合到接收器的单个天线，沿着任意轨迹在空间上转换来合成天线阵列。当天线被空间转换时，数据处理装置根据由系统时钟提供的时钟信号对输入信号进行采样。通过在任意轨迹上的不同空间位置的不同时间采样输入信号，该系统充当合成天线阵列。在不同时间和位置的输入信号的不同采样提供信号分集增益以及可用于检测输入信号的不同读数。本发明适用于在各种条件下检测无线通信信号或GNSS信号。该系统可以包括至少一个传感器，其可以提供用于计算与任意轨迹有关的数据的数据。

10. 外观设计

USD558466S1 Portable cot 有权
标题翻译：便携式婴儿床
公开(公告)号：USD558466S1
公开(公告)日：2008-01-01
申请号：US29255950
申请日：2006-03-14
申请人： Jon Seddon , John Nielsen
设计人： Jon Seddon , John Nielsen

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