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1. 发明申请

US20070110747A1 Binding agents 有权
标题翻译：结合剂
公开(公告)号：US20070110747A1
公开(公告)日：2007-05-17
申请号：US11411003
申请日：2006-04-25
申请人： Christopher Paszty , Martyn Robinson , Kevin Graham , Alistair Henry , Kelly Hoffmann , John Latham , Hsieng Lu , Alastair Lawson , Andy Popplewell , Wenyan Shen , David Winkler , Aaron Winters
发明人： Christopher Paszty , Martyn Robinson , Kevin Graham , Alistair Henry , Kelly Hoffmann , John Latham , Hsieng Lu , Alastair Lawson , Andy Popplewell , Wenyan Shen , David Winkler , Aaron Winters
IPC分类号： A61K39/395 , G01N33/567 , C07K16/18
CPC分类号： C07K16/22 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K2039/505 , C07K14/76 , C07K14/79 , C07K16/18 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/30
摘要： Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
摘要翻译：提供了与硬骨素蛋白表位有关的组合物和方法，以及硬骨素结合剂，例如能结合硬化蛋白的抗体。

2. 发明申请

US20070072797A1 Epitopes 有权
标题翻译：表皮
公开(公告)号：US20070072797A1
公开(公告)日：2007-03-29
申请号：US11410540
申请日：2006-04-25
申请人： Martyn Robinson , Alistair Henry , Alastair Lawson , Hsieng Lu , Christopher Paszty , Kelly Hoffmann , John Latham , David Winkler , Aaron Winters
发明人： Martyn Robinson , Alistair Henry , Alastair Lawson , Hsieng Lu , Christopher Paszty , Kelly Hoffmann , John Latham , David Winkler , Aaron Winters
IPC分类号： A61K38/17 , C07K14/705 , C07K16/28 , C07H21/04 , C12P21/06
CPC分类号： C07K16/18 , A61K2039/505 , C07K14/51 , C07K16/22 , C07K2317/24 , C07K2317/76 , C07K2317/92 , C12N15/63
摘要： Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided.
摘要翻译：提供了与硬骨素蛋白表位有关的组合物和方法，以及硬骨素结合剂，例如能结合硬化蛋白的抗体。

3. 发明申请

US20090047423A1 Formation of layers on substrates 失效
标题翻译：在基底上形成层
公开(公告)号：US20090047423A1
公开(公告)日：2009-02-19
申请号：US11920621
申请日：2006-05-16
申请人： Martyn Robinson
发明人： Martyn Robinson
IPC分类号： B05D5/12 , C09D183/04 , B05D3/10 , B05D5/00
CPC分类号： C23C18/30 , B41M3/006 , B41M5/0047 , B41M5/0064 , C23C18/1608
摘要： A liquid composition for forming an activator-containing layer on a substrate, for activating a chemical reaction to produce a solid layer on the substrate, comprises activator, surfactant and solvent and/or binder. The liquid composition is deposited on a surface of a substrate, desirably by inkjet printing. The layer is used to activate a chemical reaction to produce a solid layer on the substrate surface, e.g. a layer of conductive metal. The surfactant in the liquid composition has beneficial effects on the behaviour of the liquid composition when applied to certain substrates.
摘要翻译：用于在基材上形成含活化剂层的液体组合物，用于在基材上活化化学反应以产生固体层，其包含活化剂，表面活性剂和溶剂和/或粘合剂。液体组合物优选通过喷墨印刷沉积在基材的表面上。该层用于激活化学反应以在衬底表面上产生固体层，例如，一层导电金属。液体组合物中的表面活性剂在施加到某些底物时对液体组合物的行为具有有益的作用。

4. 发明申请

US20070054354A1 E.coli host cells with modified phos/psts periplasmic phosphate-binding proteins, and method of manufacturing recombinant fabs 有权
标题翻译：具有修饰的phos / psts周质磷酸结合蛋白的大肠杆菌宿主细胞，以及重组生产厂的制造方法
公开(公告)号：US20070054354A1
公开(公告)日：2007-03-08
申请号：US10531402
申请日：2003-10-15
申请人： David Humphreys , Andrew Chapman , Martyn Robinson , Mariangela Spitali
发明人： David Humphreys , Andrew Chapman , Martyn Robinson , Mariangela Spitali
IPC分类号： C12P21/06 , C12N1/21 , C07H21/04 , C12N15/74 , C07K16/18
CPC分类号： C07K14/245 , C12N1/20
摘要： The present invention provides an Ecoli host cell expressing a recombinant antibody characterized in that the Ecoli host cell has been genetically modified in order to change at least one physical property of one or more Ecoli proteins which in the wild type copurify with said recombinant antibody.
摘要翻译：本发明提供了表达重组抗体的大肠杆菌宿主细胞，其特征在于已将遗传修饰的大肠杆菌宿主细胞改变为野生型与所述重组抗体共培养的一种或多种大肠杆菌蛋白质的至少一种物理性质。

5. 发明申请

US20070269428A1 Method for the Treatment of Multiple Sclerosis by Inhibiting Il-17 Activity 审中-公开
标题翻译：通过抑制II-17活性治疗多发性硬化症的方法
公开(公告)号：US20070269428A1
公开(公告)日：2007-11-22
申请号：US10580164
申请日：2004-11-16
申请人： Mark Christie , Richard Mead , Martyn Robinson , Stephen Rapecki
发明人： Mark Christie , Richard Mead , Martyn Robinson , Stephen Rapecki
IPC分类号： A61K39/395 , A61K47/48 , A61P37/00 , C07K16/18 , C07K16/24
CPC分类号： C07K16/244 , A61K47/60 , A61K47/6845 , A61K2039/505 , C07K2317/55 , C07K2317/76
摘要： The present invention provides a method for the treatment and/or prophylaxis of multiple sclerosis (MS) comprising administering a therapeutically effective amount of an inhibitor of IL-17 activity.
摘要翻译：本发明提供了治疗和/或预防多发性硬化（MS）的方法，包括给予治疗有效量的IL-17活性抑制剂。

6. 发明申请

US20060134318A1 Method of forming a conductive metal region on a substrate 审中-公开
标题翻译：在基板上形成导电金属区域的方法
公开(公告)号：US20060134318A1
公开(公告)日：2006-06-22
申请号：US10543311
申请日：2004-01-28
申请人： Alan Hudd , Philip Bentley , James Fox , Martyn Robinson
发明人： Alan Hudd , Philip Bentley , James Fox , Martyn Robinson
IPC分类号： B28B19/00 , B05D5/12
CPC分类号： C23C18/1678 , B42D25/373 , C23C18/1608 , C23C18/161 , C23C18/1651 , C23C18/1658 , C23C18/1676 , H01M10/04 , H05K1/095 , H05K3/125 , H05K3/182 , H05K3/305 , H05K2201/10477 , H05K2203/013 , H05K2203/0709 , H05K2203/1157 , H05K2203/1163 , H05K2203/1469
摘要： There is disclosed a method of forming a conductive metal region on a substrate, comprising depositing on the substrate a solution of a metal ion, and depositing on the substrate a solution of a reducing agent, such that the metal ion and the reducing agent react together in a reaction solution to form a conductive metal region on the substrate.
摘要翻译：公开了一种在衬底上形成导电金属区域的方法，包括在衬底上沉积金属离子溶液，并在衬底上沉积还原剂的溶液，使得金属离子和还原剂一起反应在反应溶液中，以在衬底上形成导电金属区域。

7. 发明申请

US20050130397A1 Formation of layers on substrates 审中-公开
标题翻译：在基底上形成层
公开(公告)号：US20050130397A1
公开(公告)日：2005-06-16
申请号：US10975499
申请日：2004-10-29
申请人： Philip Bentley , James Fox , Alan Hudd , Martyn Robinson
发明人： Philip Bentley , James Fox , Alan Hudd , Martyn Robinson
IPC分类号： C23C18/28 , H01L21/20 , H05K3/18 , H05K3/38
CPC分类号： H05K3/182 , C23C18/1608 , C23C18/1879 , C23C18/1882 , C23C18/206 , C23C18/2066 , C23C18/28 , C23C18/30 , H01L2924/3025 , H05K3/387 , H05K2201/0236 , H05K2203/013 , H05K2203/0709 , H01L2924/00
摘要： Disclosed is a method of forming, on the surface of a substrate, a first layer which is suitable for activating a second solid-layer-forming chemical reaction thereon, the method comprising the steps of bringing into contact with the substrate a first liquid which forms a first solid layer thereon, the first liquid comprising an activator for the second solid-layer-forming chemical reaction, characterised in that the first liquid is selected so that the first solid layer adheres to the substrate and is permeable to a second liquid that comprises one or more reagents for the second solid-layer-forming chemical reaction. A second solid layer can then be formed on the substrate by bringing into contact with the first solid layer a second liquid comprising one or more reagents for the second solid-layer-forming reaction.
摘要翻译：公开了一种在基板的表面上形成适于在其上激活第二固体层形成化学反应的第一层的方法，所述方法包括以下步骤：与基板接触形成第一液体的步骤其上的第一固体层，所述第一液体包含用于第二固体层形成化学反应的活化剂，其特征在于，所述第一液体被选择为使得所述第一固体层粘附到所述基底并且可渗透第二液体，所述第二液体包含用于第二固体层形成化学反应的一种或多种试剂。然后可以通过与第一固体层接触包含用于第二固体层形成反应的一种或多种试剂的第二液体在基底上形成第二固体层。

8. 发明授权

US08642117B2 Formation of layers on substrates 失效
标题翻译：在基底上形成层
公开(公告)号：US08642117B2
公开(公告)日：2014-02-04
申请号：US11920621
申请日：2006-05-16
申请人： Martyn Robinson
发明人： Martyn Robinson
IPC分类号： B05D5/12 , B05D3/04
CPC分类号： C23C18/30 , B41M3/006 , B41M5/0047 , B41M5/0064 , C23C18/1608
摘要： A liquid composition for forming an activator-containing layer on a substrate, for activating a chemical reaction to produce a solid layer on the substrate, comprises activator, surfactant and solvent and/or binder. The liquid composition is deposited on a surface of a substrate, desirably by inkjet printing. The layer is used to activate a chemical reaction to produce a solid layer on the substrate surface, e.g. a layer of conductive metal. The surfactant in the liquid composition has beneficial effects on the behavior of the liquid composition when applied to certain substrates.
摘要翻译：用于在基材上形成含活化剂层的液体组合物，用于在基材上活化化学反应以产生固体层，其包含活化剂，表面活性剂和溶剂和/或粘合剂。液体组合物优选通过喷墨印刷沉积在基材的表面上。该层用于激活化学反应以在衬底表面上产生固体层，例如，一层导电金属。液体组合物中的表面活性剂在施加到某些底物时对液体组合物的行为具有有益的作用。

9. 发明申请

US20050153078A1 Formation of solid layers on substrates 有权
标题翻译：在基底上形成固体层
公开(公告)号：US20050153078A1
公开(公告)日：2005-07-14
申请号：US11002646
申请日：2004-12-03
申请人： Philip Bentley , James Fox , Alan Hudd , Martyn Robinson
发明人： Philip Bentley , James Fox , Alan Hudd , Martyn Robinson
IPC分类号： C23C18/16 , C23C18/30 , H01M4/04 , H01M6/40 , H01M8/02 , H05K3/18 , B05D7/00 , B05D1/36 , H01C1/00
CPC分类号： H01M4/0414 , C23C18/1608 , C23C18/161 , C23C18/1651 , C23C18/1653 , C23C18/206 , C23C18/2066 , C23C18/30 , C23C18/405 , H01M4/04 , H01M4/0404 , H01M4/0416 , H01M4/049 , H01M4/0492 , H01M6/40 , H01M8/0228 , H05K3/182 , H05K2203/013 , H05K2203/0709 , H05K2203/1157 , Y10T428/31699
摘要： Disclosed is a method of forming on the surface of a substrate a first solid layer which is suitable for activating a chemical reaction to form a second layer thereon, the method comprising the steps of: applying to the surface of the substrate a first liquid comprising a curable composition and an activator for the second layer-forming chemical reaction; and curing the curable composition, thereby forming a first solid layer adhered to the surface of the substrate, capable of activating the second layer-forming chemical reaction. A second layer can then be formed on the substrate by bringing into contact with the first solid layer a second fluid comprising components of a second layer-forming chemical reaction, activated by the activator, thereby causing a second layer to be formed on the first solid layer.
摘要翻译：公开了一种在衬底的表面上形成第一固体层的方法，所述第一固体层适于激活化学反应以在其上形成第二层，所述方法包括以下步骤：向衬底的表面施加包含可固化组合物和用于第二层形成化学反应的活化剂; 使固化性组合物固化，从而形成附着于基材表面的第一固体层，能够活化第二层形成化学反应。然后可以通过与第一固体层接触的第二层形成第二层，第二流体包含由活化剂活化的第二层形成化学反应的组分，从而在第一固体上形成第二层层。

10. 发明申请

US20050141150A1 Electrical connection of components 有权
标题翻译：组件的电气连接
公开(公告)号：US20050141150A1
公开(公告)日：2005-06-30
申请号：US10975500
申请日：2004-10-29
申请人： Philip Bentley , James Fox , Alan Hudd , Martyn Robinson , Michael Johnson , Ian Williamson
发明人： Philip Bentley , James Fox , Alan Hudd , Martyn Robinson , Michael Johnson , Ian Williamson
IPC分类号： C23C18/16 , H01L21/60 , H01L23/538 , H05K3/18 , H05K3/32 , H02H3/00
CPC分类号： H01L23/5389 , C23C18/1608 , C23C18/1621 , C23C18/208 , H01L24/24 , H01L24/82 , H01L2224/05553 , H01L2224/24051 , H01L2224/24226 , H01L2224/24998 , H01L2224/45124 , H01L2224/76155 , H01L2224/82007 , H01L2224/82102 , H01L2924/00014 , H01L2924/01006 , H01L2924/01013 , H01L2924/01029 , H01L2924/01033 , H01L2924/01046 , H01L2924/01047 , H01L2924/01074 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/014 , H01L2924/12041 , H01L2924/12042 , H01L2924/12043 , H01L2924/12044 , H01L2924/19041 , H01L2924/19042 , H01L2924/19043 , H05K3/182 , H05K3/32 , H05K2201/10477 , H05K2203/013 , H05K2203/0709 , H05K2203/1469 , Y10T29/49117 , Y10T29/4913 , Y10T29/49131 , Y10T29/49144 , H01L2924/00 , H01L2224/48
摘要： A contact of a component is electrically connected to an associated contact of an electrical circuit, typically formed on a substrate, by depositing material between the contacts, the material forming or being processed to form an electrical connection between the contacts. The invention also provides apparatus for this purpose and a resulting circuit.
摘要翻译：组件的触点通常在触点之间沉积材料，形成或被处理以在触点之间形成电连接的材料，电连接到通常形成在基板上的电路的相关触头。本发明还提供了用于该目的的装置以及所产生的电路。

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