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1. 发明申请

US20100204083A1 PROCESS FOR THE PREPARATION OF ETHYLGERANONITRILE 审中-公开
标题翻译：乙酰胆碱酯酶的制备方法
公开(公告)号：US20100204083A1
公开(公告)日：2010-08-12
申请号：US12670689
申请日：2008-07-16
申请人： Martine Weis , Bernhard Brunner , Klaus Ebel , Wolfgang Krause
发明人： Martine Weis , Bernhard Brunner , Klaus Ebel , Wolfgang Krause
IPC分类号： C07C253/30 , A61K8/40
CPC分类号： C11B9/0023 , A61K8/40 , A61L9/01 , A61Q13/00 , C07C253/30 , C07C255/07 , C11D3/50
摘要： The present invention relates to a method of producing ethylgeranonitrile through reaction of ethylheptenone with a deprotonated nitrile and, if appropriate, subsequent saponification and decarboxylation. Moreover, the invention relates to mixtures comprising 3,7-dimethyl-2,6-nonadienenitrile and at least one compound selected from the group of compounds 3,7-dimethyl-3,6-nonadienenitrile and 3-methylene-7-methyl-6-nonenenitrile, and to fragrance compositions comprising these.
摘要翻译：本发明涉及通过乙基庚烯酮与去质子化腈的反应以及如果合适的话随后皂化和脱羧反应生产乙腈的方法。此外，本发明涉及包含3,7-二甲基-2,6-壬二腈和至少一种选自化合物3,7-二甲基-3,6-壬二腈和3-亚甲基-7-甲基 - 6-壬烯腈，以及包含它们的香料组合物。

2. 发明申请

US20130005641A1 MACROCYCLIC LACTONES 有权
标题翻译：大肠杆菌
公开(公告)号：US20130005641A1
公开(公告)日：2013-01-03
申请号：US13537823
申请日：2012-06-29
申请人： Klaus Ebel , Bernhard Brunner , Christoph Stock , Ralf Pelzer
发明人： Klaus Ebel , Bernhard Brunner , Christoph Stock , Ralf Pelzer
IPC分类号： C07D313/00 , A61Q13/00 , A61K8/49
CPC分类号： C07D313/00 , A61K8/4973 , A61Q13/00
摘要： The present invention relates to novel macrocyclic lactones, to processes for their preparation and to their use as fragrances and also to products comprising the novel macrocyclic lactones.
摘要翻译：本发明涉及新型大环内酯，其制备方法及其作为香料的用途，以及包含新型大环内酯的产品。

3. 发明授权

US08410293B2 Process for the preparation of cyclic enol ethers 有权
标题翻译：环烯醇醚的制备方法
公开(公告)号：US08410293B2
公开(公告)日：2013-04-02
申请号：US13536036
申请日：2012-06-28
申请人： Klaus Ebel , Bernhard Brunner , Christoph Stock , Ralf Pelzer
发明人： Klaus Ebel , Bernhard Brunner , Christoph Stock , Ralf Pelzer
IPC分类号： C07D309/18 , C07D311/74 , C07D307/28 , C07D307/79
CPC分类号： C07D311/94 , C07D307/93 , Y02P20/127
摘要： The present invention relates to a process for the preparation of cyclic enol ethers.
摘要翻译：本发明涉及环烯醇醚的制备方法。

4. 发明申请

US20130005994A1 PROCESS FOR THE PREPARATION OF CYCLIC ENOL ETHERS 有权
标题翻译：制备循环环氧酶的方法
公开(公告)号：US20130005994A1
公开(公告)日：2013-01-03
申请号：US13536036
申请日：2012-06-28
申请人： Klaus Ebel , Bernhard Brunner , Christoph Stock , Ralf Pelzer
发明人： Klaus Ebel , Bernhard Brunner , Christoph Stock , Ralf Pelzer
IPC分类号： C07D307/93 , C07D311/94
CPC分类号： C07D311/94 , C07D307/93 , Y02P20/127
摘要： The present invention relates to a process for the preparation of cyclic enol ethers.
摘要翻译：本发明涉及环烯醇醚的制备方法。

5. 发明授权

US08648031B2 Macrocyclic lactones 有权
标题翻译：大环内酯
公开(公告)号：US08648031B2
公开(公告)日：2014-02-11
申请号：US13537823
申请日：2012-06-29
申请人： Klaus Ebel , Bernhard Brunner , Christoph Stock , Ralf Pelzer
发明人： Klaus Ebel , Bernhard Brunner , Christoph Stock , Ralf Pelzer
IPC分类号： A61Q13/00
CPC分类号： C07D313/00 , A61K8/4973 , A61Q13/00
摘要： The present invention relates to novel macrocyclic lactones, to processes for their preparation and to their use as fragrances and also to products comprising the novel macrocyclic lactones.
摘要翻译：本发明涉及新型大环内酯，其制备方法及其作为香料的用途，以及包含新型大环内酯的产品。

6. 发明授权

US5725810A Packing for a counterflow high pressure column 失效
标题翻译：逆流高压塔包装
公开(公告)号：US5725810A
公开(公告)日：1998-03-10
申请号：US732026
申请日：1996-10-16
申请人： Bernhard Brunner , Philipp Suess
发明人： Bernhard Brunner , Philipp Suess
IPC分类号： B01D3/00 , B01J19/32 , B01F3/04
CPC分类号： B01J19/32 , B01D3/008 , B01J2219/3221 , B01J2219/32213 , B01J2219/32268 , B01J2219/32272 , B01J2219/32275 , B01J2219/32466
摘要： The packing for a counterflow high pressure column contains an ordered array of shaped lamella aligned parallel to the column axis. The packing comprises a bundle of strings extending in the direction of the column axis. Each string consists of a stack of packing elements, with adjacent elements belonging to different strings respectively forming a packing section perpendicular to the column axis. Each packing element is constructed in layers formed by the lamella. The layers are oriented in such a manner that gap-like or channel-like intermediate spaces between the lamella are laterally bounded by transversely lying lamella of adjacent packing elements belonging to the same packing section.
摘要翻译：用于逆流高压塔的包装包含平行于列轴线排列的成形薄片的有序阵列。包装包括沿列轴线方向延伸的一束绳。每个串由堆叠的填充元件组成，相邻的元件属于不同的串，分别形成垂直于列轴线的填充部分。每个包装元件由薄片形成的层构成。这些层以这样一种方式定向，使得薄片之间的间隙状或通道状的中间空间由属于同一包装部分的相邻填料元件的横向间隔的薄片横向限定。

7. 发明申请

US20080127727A1 Piezoelectric Sensor Comprising a Thermal Sensor and an Amplifier Circuit 审中-公开
标题翻译：包含热传感器和放大器电路的压电传感器
公开(公告)号：US20080127727A1
公开(公告)日：2008-06-05
申请号：US11815150
申请日：2006-02-14
申请人： Bernhard Brunner , Dieter Sporn , Gerhard Domann , Peter Spies , Frank Forster , Javier Gutierrez Boronat , Ruth Houbertz-Krauss
发明人： Bernhard Brunner , Dieter Sporn , Gerhard Domann , Peter Spies , Frank Forster , Javier Gutierrez Boronat , Ruth Houbertz-Krauss
IPC分类号： G01P15/09
CPC分类号： G01P15/09 , G01D3/0365 , G01H11/08 , H01L41/1132
摘要： The invention relates to a piezoelectric sensor which comprises a piezoelectric measuring transducer, an amplifier circuit and also at least one connection for external current or signal lines, these elements being integrated on or in a carrier structure. The sensor thereby enables measurement under different temperature conditions. The piezoelectric sensor according to the invention is used for oscillation, acceleration or deflection measurement, in particular in mechanical engineering, in air and space travel or in the automobile industry.
摘要翻译：本发明涉及一种压电传感器，其包括压电测量传感器，放大器电路以及用于外部电流或信号线的至少一个连接，这些元件集成在载体结构上或载体结构中。因此，传感器能够在不同的温度条件下进行测量。根据本发明的压电传感器用于振动，加速或偏转测量，特别是在机械工程，空气和空间行程或汽车工业中。

8. 发明授权

US4448776A Method of using certain substituted aliphatic secondary amines or their salts for easing breathing 失效
标题翻译：使用某些取代的脂族仲胺或其盐来缓解呼吸的方法
公开(公告)号：US4448776A
公开(公告)日：1984-05-15
申请号：US341035
申请日：1982-01-20
申请人： Karl Bucher , Max Matter , Bernhard Brunner , Alfred Frey
发明人： Karl Bucher , Max Matter , Bernhard Brunner , Alfred Frey
IPC分类号： A61K31/13 , A61K31/135 , A61K31/195 , A61K31/215 , A61P11/10 , C07C67/00 , C07C209/00 , C07C209/08 , C07C209/52 , C07C211/27 , C07C229/36 , C07C229/38 , A61K31/24 , A61K31/495
CPC分类号： C07C229/38
摘要： Compounds of the formula IR.sub.1 --CH(R.sub.2)--N(R.sub.3)--R.sub.4 (I)in which R.sub.1 is unsubstituted or substituted phenyl, R.sub.2 is hydrogen lower alkyl, unsubstituted or substituted phenyl or free or esterified carboxy, and in which R.sub.3 is hydrogen or lower alkyl and R.sub.4 is a group of the formula --alk.sub.1 --X--alk.sub.2 --R.sub.5, or R.sub.3 and R.sub.4 together are a group of the formula --alk.sub.3 --NH--alk.sub.4 --, alk.sub.1 and alk.sub.2 being lower alkylidene, alk.sub.3 and alk.sub.4 lower alkylene, X a direct bond, methylene or unsubstituted or substituted phenylene and R.sub.5 being hydroxy, amino or substituted amino of the formula --N(R.sub.6)--CH(R.sub.7)--R.sub.8 in which R.sub.6 is hydrogen, or, provided that R.sub.3 is hydrogen, it may alternatively be lower alkyl or unsubstituted or substituted phenyl-lower alkyl, R.sub.7 is hydrogen, lower alkyl, unsubstituted or substituted phenyl or free or esterified carboxy and R.sub.8 is unsubstituted or substituted phenyl, and their pharmaceutically acceptable salts have properties that ease breathing and are suitable for combating respiratory disorders, preferably as active ingredients in and/or for the manufacture of pharmaceutical preparations that ease breathing.
摘要翻译：其中R 1为未取代或取代的苯基，R 2为氢低级烷基，未取代或取代的苯基或游离的或酯化的羧基，其中R 1，R 2，R 3，是氢或低级烷基，R4是式-alk1-X-alk2-R5的基团，或R3和R4一起是式-alk3-NH-alk4-，alk1和alk2是低级亚烷基，alk3和烷基，低级亚烷基，X为直接键，亚甲基或未取代或取代的亚苯基，R5为羟基，式-N（R6）-CH（R7）-R8的氨基或取代的氨基，其中R6为氢，或可以是低级烷基或未取代的或取代的苯基 - 低级烷基，R7是氢，低级烷基，未取代或取代的苯基或游离或酯化的羧基，R8是未取代或取代的苯基，其药学上可接受的盐具有舒适呼吸，适合对抗呼吸系统疾病，优先可以作为促进呼吸的药物制剂的制造和/或制造中的活性成分。

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