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    • 6. 发明授权
    • Systems and methods for delivery of peritoneal dialysis (PD) solutions with integrated inter-chamber diffuser
    • 用集成腔室内扩散器输送腹膜透析(PD)溶液的系统和方法
    • US09585810B2
    • 2017-03-07
    • US12904637
    • 2010-10-14
    • Lynn E. JensenVenugopal R. GhatikarDeLoy LindleyMelvin D. Jensen
    • Lynn E. JensenVenugopal R. GhatikarDeLoy LindleyMelvin D. Jensen
    • A61M1/28A61J1/10A61J1/20
    • A61J1/10A61J1/2003A61J1/2013A61J1/2027A61J1/2089A61J1/2093A61K9/08A61K47/02A61K47/12A61K47/26A61M1/287
    • The invention provides, in some aspects, a container system for medical solutions such as peritoneal dialysis (PD) solutions. The invention particularly features a system which includes a first compartment that contains a first medical solution, e.g., a PD osmotic agent, and a second compartment that contains a second medical solution, e.g., a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. To that end, a container system can include a diffuser that is disposed in a fluid pathway between the first and second compartments, e.g., to facilitate homogeneous mixing of the first and second PD agents. That diffuser is disposed within and moves relative to a structure, such as a port that defines the fluid pathway between those compartment. Thus, for example, the diffuser can comprise a body that “floats” within that pathway-defining structure and that moves from one end to the other (and/or to from points there between), depending on a direction of solution flow through the structure.
    • 本发明在一些方面提供了一种用于医疗溶液例如腹膜透析(PD)溶液的容器系统。 本发明特别地涉及一种系统,其包括含有第一药液(例如PD渗透剂)的第一隔室和含有第二药液(例如PD缓冲剂)的第二隔室。 为了运输,储存和/或灭菌的目的,隔间将它们各自的内容物彼此分开。 然而,隔室是可流体耦合的,使得它们各自的内容物可以彼此组合,例如在药剂灭菌之后并且在引入患者腹部之前。 为此,容器系统可以包括设置在第一和第二隔室之间的流体通路中的扩散器,例如以促进第一和第二PD试剂的均匀混合。 该扩散器设置在诸如限定这些隔室之间的流体通道的端口的结构内并且相对于结构移动。 因此,例如,漫射器可以包括在该路径限定结构内“浮动”并且从一端移动到另一端(和/或从其之间的点)移动的主体,这取决于溶液流动的方向 结构体。
    • 7. 发明申请
    • SYSTEMS AND METHODS FOR DELIVERY OF PERITONEAL DIALYSIS (PD) SOLUTIONS WITH INTEGRATED INTER-CHAMBER DIFFUSER
    • 用于递送具有集成的室内扩散器的透析(PD)解决方案的系统和方法
    • US20120095392A1
    • 2012-04-19
    • US12904637
    • 2010-10-14
    • Lynn E. JensenVenugopal R. GhatikarDeLoy LindleyMelvin D. Jensen
    • Lynn E. JensenVenugopal R. GhatikarDeLoy LindleyMelvin D. Jensen
    • A61M1/28
    • A61J1/10A61J1/2003A61J1/2013A61J1/2027A61J1/2089A61J1/2093A61K9/08A61K47/02A61K47/12A61K47/26A61M1/287
    • The invention provides, in some aspects, a container system for medical solutions such as peritoneal dialysis (PD) solutions. The invention particularly features a system which includes a first compartment that contains a first medical solution, e.g., a PD osmotic agent, and a second compartment that contains a second medical solution, e.g., a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. To that end, a container system can include a diffuser that is disposed in a fluid pathway between the first and second compartments, e.g., to facilitate homogeneous mixing of the first and second PD agents. That diffuser is disposed within and moves relative to a structure, such as a port that defines the fluid pathway between those compartment. Thus, for example, the diffuser can comprise a body that “floats” within that pathway-defining structure and that moves from one end to the other (and/or to from points there between), depending on a direction of solution flow through the structure.
    • 本发明在一些方面提供了一种用于医疗溶液例如腹膜透析(PD)溶液的容器系统。 本发明特别地涉及一种系统,其包括含有第一药液(例如PD渗透剂)的第一隔室和含有第二药液(例如PD缓冲剂)的第二隔室。 为了运输,储存和/或灭菌的目的,隔间将它们各自的内容物彼此分开。 然而,隔室是可流体耦合的,使得它们各自的内容物可以彼此组合,例如在药剂灭菌之后并且在引入患者腹部之前。 为此,容器系统可以包括设置在第一和第二隔室之间的流体通路中的扩散器,例如以促进第一和第二PD试剂的均匀混合。 该扩散器设置在诸如限定这些隔室之间的流体通道的端口的结构内并且相对于结构移动。 因此,例如,漫射器可以包括在该路径限定结构内“浮动”并且从一端移动到另一端(和/或从其之间的点)的主体,这取决于溶液流动的方向 结构体。