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1. 发明授权

US07704943B2 Transglutaminase for inhibiting angiogenesis 失效
标题翻译：用于抑制血管发生的转谷氨酰胺酶
公开(公告)号：US07704943B2
公开(公告)日：2010-04-27
申请号：US10344084
申请日：2001-08-08
申请人： Martin Griffin , Richard Jones
发明人： Martin Griffin , Richard Jones
IPC分类号： A61K38/00 , A61K38/04 , C07K14/00
CPC分类号： A61K38/45
摘要： The present invention relates to use of a transglutaminase in the preparation of a medicament for inhibiting angiogenesis. Preferably, the transglutaminase is a human tissue transglutaminase. Advantageously, the medicament is for treating cancer, rheumatoid arthritis, retinopathy and/or psoriasis. Additionally, the invention relates to compositions comprising a transglutaminase in an amount sufficient to inhibit angiogenesis.
摘要翻译：本发明涉及转谷氨酰胺酶在制备用于抑制血管发生的药物中的用途。优选地，转谷氨酰胺酶是人组织转谷氨酰胺酶。有利地，该药物用于治疗癌症，类风湿性关节炎，视网膜病和/或牛皮癣。另外，本发明涉及包含足以抑制血管生成的量的转谷氨酰胺酶的组合物。

2. 发明授权

US09482535B2 Integrated silicon optomechanical gyroscopes (OMGs) 有权
标题翻译：集成硅光机械陀螺仪（OMG）
公开(公告)号：US09482535B2
公开(公告)日：2016-11-01
申请号：US13996669
申请日：2011-12-23
申请人： John Heck , Haisheng Rong , Richard Jones
发明人： John Heck , Haisheng Rong , Richard Jones
IPC分类号： G01C19/66 , G01C19/5684
CPC分类号： G01C19/661 , G01C19/5684
摘要： A system having an optomechanical gyroscope device. An optomechanical disk acts as an optical ring resonator and a mechanical disk resonator. A drive laser generates an optical drive signal. A drive channel acts as a waveguide for the optical drive signal and includes drive electrodes in a first proximity with respect to the optomechanical disk. The drive electrodes to excite the ring by evanescent coupling. A drive photodetector is configured to receive an output optical signal from the drive channel. A sense laser generates a optical sense signal. A sense channel acts as a waveguide for the optical sense signal and includes sense electrodes in a second proximity with respect to the optomechanical disk. A sense photodetector is configured to receive an output optical signal from the sense channel.
摘要翻译：具有光学陀螺仪装置的系统。光学机械盘用作光环谐振器和机械盘谐振器。驱动激光器产生光驱动信号。驱动通道用作用于光驱动信号的波导，并且包括相对于机电盘第一接近的驱动电极。驱动电极通过ev逝耦合激发环。驱动光电检测器被配置为从驱动通道接收输出光信号。感测激光产生光学感测信号。感测通道用作光学感测信号的波导，并且包括相对于光学机械盘的第二接近度的感测电极。感测光电检测器被配置为从感测通道接收输出光信号。

3. 发明申请

US20160200445A1 AIRCRAFT SAFETY DEVICE SYSTEMS 审中-公开
标题翻译：飞机安全装置系统
公开(公告)号：US20160200445A1
公开(公告)日：2016-07-14
申请号：US15080300
申请日：2016-03-24
申请人： Richard Jones , Terrell Jones
发明人： Richard Jones , Terrell Jones
IPC分类号： B64D33/02
CPC分类号： B64D33/02 , B64D2033/022 , B64D2033/0286 , F02C7/055
摘要： An aircraft system comprising a deflector assembly including, a base having mounting apertures; an inner ring concentrically positioned within an outer ring, the inner ring and the outer ring have an annulus defined therebetween via a base plate, a plurality of rods attached within the annulus and culminating at an apex creating a conical profile; and a forward-mounted cone-shaped deflecting member. The base plate comprises a through hole allowing airflow through the deflector assembly to supply an airplane engine. The aircraft safety device system further comprises at least one locking latch for removably securing the deflector assembly to a housing of the airplane engine. The aircraft safety device is mountable inside a lip of the housing of the airplane engine. Further, the aircraft safety device provides protection for airplane engines from air born animate and inanimate objects.
摘要翻译：一种飞行器系统，包括偏转器组件，该偏转器组件包括：具有安装孔的底座; 内圈同心地定位在外圈内，内环和外环具有通过基板在其间限定的环，多个杆附接在环形空间内并且在顶点达到顶点，产生锥形轮廓; 和前置锥形偏转构件。基板包括通孔，允许气流通过偏转器组件以供应飞机发动机。飞机安全装置系统还包括至少一个锁定闩锁，用于可拆卸地将偏转器组件固定到飞机发动机的壳体上。飞机安全装置可安装在飞机发动机壳体的唇部内。此外，飞机安全装置为空中出生的动画和无生命物体提供对飞机发动机的保护。

4. 发明授权

US08716840B2 Backside thermal patterning of buried oxide (BOX) 有权
标题翻译：掩埋氧化物背面热图案（BOX）
公开(公告)号：US08716840B2
公开(公告)日：2014-05-06
申请号：US12060177
申请日：2008-03-31
申请人： Richard Jones
发明人： Richard Jones
IPC分类号： H01L29/02 , H01L21/311
CPC分类号： H01L29/02 , H01L21/311 , H01L21/7624 , H01S5/021 , H01S5/0261
摘要： The dominant source of thermal resistance for silicon photonic devices patterned on SOI wafers is the buried oxide layer. To ensure efficient thermally driven silicon devices there is a need for a large thermal resistance. This is in contrast to temperature sensitive components need to have low thermal resistance in order to reduce their temperature to ensure good performance. Embodiments comprise etching the back of an SOI wafer to expose the buried oxide layer and depositing an additional layer of silicon oxide to increase the local thermal resistance. Thus, embodiments provide the ability to tailor the thermal resistance across the wafer or die depending on the device being fabricated.
摘要翻译：在SOI晶片上图案化的硅光子器件的主要热阻源是掩埋氧化物层。为了确保有效的热驱动硅器件，需要大的热阻。这与温度敏感元件相比，需要具有低热阻，以降低其温度以确保良好的性能。实施例包括蚀刻SOI晶片的背面以暴露掩埋氧化物层并沉积附加的氧化硅层以增加局部热阻。因此，实施例提供了根据正在制造的器件来跨越晶片或管芯定制热阻的能力。

5. 发明申请

US20130293898A1 INTEGRATED SILICON OPTOMECHANICAL GYROSCOPES (OMGS) 有权
标题翻译：综合硅光电陀螺（OMGS）
公开(公告)号：US20130293898A1
公开(公告)日：2013-11-07
申请号：US13996669
申请日：2011-12-23
申请人： John Heck , Haisheng Rong , Richard Jones
发明人： John Heck , Haisheng Rong , Richard Jones
IPC分类号： G01C19/66
CPC分类号： G01C19/661 , G01C19/5684
摘要： A system having an optomechanical gyroscope device. An optomechanical disk acts as an optical ring resonator and a mechanical disk resonator. A drive laser generates an optical drive signal. A drive channel acts as a waveguide for the optical drive signal and includes drive electrodes in a first proximity with respect to the optomechanical disk. The drive electrodes to excite the ring by evanescent coupling. A drive photodetector is configured to receive an output optical signal from the drive channel. A sense laser generates a optical sense signal. A sense channel acts as a waveguide for the optical sense signal and includes sense electrodes in a second proximity with respect to the optomechanical disk. A sense photodetector is configured to receive an output optical signal from the sense channel.
摘要翻译：具有光学陀螺仪装置的系统。光学机械盘用作光环谐振器和机械盘谐振器。驱动激光器产生光驱动信号。驱动通道用作用于光驱动信号的波导，并且包括相对于机电盘第一接近的驱动电极。驱动电极通过ev逝耦合激发环。驱动光电检测器被配置为从驱动通道接收输出光信号。感测激光产生光学感测信号。感测通道用作光学感测信号的波导，并且包括相对于光学机械盘的第二接近度的感测电极。感测光电检测器被配置为从感测通道接收输出光信号。

6. 发明申请

US20130017996A1 MUTEINS OF TEAR LIPOCALIN AND METHODS FOR OBTAINING THE SAME 有权
公开(公告)号：US20130017996A1
公开(公告)日：2013-01-17
申请号：US13616815
申请日：2012-09-14
申请人： Kristian Jensen , Martin Huelsmeyer , Steffen Schlehuber , Andreas Hohlbaum , Arne Skerra , Eric Boudreau , Richard Jones , Ian Kimber , Rebecca Dearman
发明人： Kristian Jensen , Martin Huelsmeyer , Steffen Schlehuber , Andreas Hohlbaum , Arne Skerra , Eric Boudreau , Richard Jones , Ian Kimber , Rebecca Dearman
IPC分类号： A61K38/17 , C12N15/12 , A61P9/00 , A61P35/00 , A61P27/02 , C12P21/02 , A61P7/10 , A61P9/08 , A61P35/02 , C12N1/21 , C12N1/19 , C12N5/10 , C07K14/475 , A61P9/10
CPC分类号： A61K38/1709 , A61K38/38 , A61K47/60 , C07K14/435 , C07K14/47 , C07K14/705 , C12N5/10 , G01N33/57407 , G01N33/57492 , G01N2333/70521
摘要： The present invention relates to novel muteins derived from human tear lipocalin. The invention also refers to a corresponding nucleic acid molecule encoding such a mutein and to a method for its generation. The invention further refers to a method for producing such a mutein. Finally, the invention is directed to a pharmaceutical composition comprising such a lipocalin mutein as well as to various uses of the mutein.

7. 发明授权

US08256670B1 System and method for granting access to a restricted access area using an approved list 有权
标题翻译：使用批准列表授予访问受限访问区域的系统和方法
公开(公告)号：US08256670B1
公开(公告)日：2012-09-04
申请号：US12966287
申请日：2010-12-13
申请人： Richard Jones , Michael V. Kutsch
发明人： Richard Jones , Michael V. Kutsch
IPC分类号： G06K5/00
CPC分类号： G07C9/00111 , G07C9/00119 , G07C2009/00793 , G07C2009/00841 , G07C2009/00976 , G07C2009/00984
摘要： A system and method for granting access to a restricted access area using an approved list is disclosed. According to one embodiment, the system may include a card reader that receives a card number from the access card; a card verifier comprising an approved list of card numbers; a card presented list of presented card numbers; and a processor that compares the card number to the approved list and compares the card number to the card presented list; and an access device. The access device grants access to the area if one of (1) the card number is on the approved list and (2) the card number is not on the presented list; and denies access to the area if the card number is not on the approved list and the card number is on the presented list.
摘要翻译：公开了一种使用批准列表授予对受限访问区域的访问权限的系统和方法。根据一个实施例，系统可以包括从接入卡接收卡号的读卡器; 一个卡片验证器，其包括一个批准的卡号列表; 提供的卡号的卡片列表; 以及处理器，将卡号与批准的列表进行比较，并将卡号与卡片列表进行比较; 和接入设备。访问设备允许访问该区域，其中一个（1）卡号在批准的列表上，和（2）卡号不在列表中; 并且如果卡号不在批准的列表上并且卡号在所呈现的列表上，则拒绝访问该区域。

8. 发明授权

US08223811B2 Narrow surface corrugated grating 有权
标题翻译：窄表面波纹光栅
公开(公告)号：US08223811B2
公开(公告)日：2012-07-17
申请号：US13160277
申请日：2011-06-14
申请人： Richard Jones
发明人： Richard Jones
IPC分类号： H01S3/10
CPC分类号： H01S5/1032 , G02B6/124 , G02B6/29325 , H01S5/021 , H01S5/0268 , H01S5/1035 , H01S5/125 , H01S5/4087
摘要： Narrow surface corrugated gratings for integrated optical components and their method of manufacture. An embodiment includes a grating having a width narrower than a width of the waveguide on which the grating is formed. In accordance with certain embodiments of the present invention, masked photolithography is employed to form narrowed gratings having a desired grating strength. In an embodiment, an optical cavity of a laser is formed with a reflector grating having a width narrower than a width of the waveguide. In another embodiment an integrated optical communication system includes one or more narrow surface corrugated gratings.
摘要翻译：用于集成光学部件的窄表面波纹光栅及其制造方法。一个实施例包括具有窄于其上形成有光栅的波导的宽度的宽度的光栅。根据本发明的某些实施例，采用掩模光刻技术来形成具有所需光栅强度的窄格栅。在一个实施例中，激光器的光腔形成有具有窄于波导宽度的宽度的反射器光栅。在另一个实施例中，集成光通信系统包括一个或多个窄波纹光栅。

9. 发明授权

US07961765B2 Narrow surface corrugated grating 有权
标题翻译：窄表面波纹光栅
公开(公告)号：US07961765B2
公开(公告)日：2011-06-14
申请号：US12415932
申请日：2009-03-31
申请人： Richard Jones
发明人： Richard Jones
IPC分类号： H01S3/10
CPC分类号： H01S5/1032 , G02B6/124 , G02B6/29325 , H01S5/021 , H01S5/0268 , H01S5/1035 , H01S5/125 , H01S5/4087
摘要： Narrow surface corrugated gratings for integrated optical components and their method of manufacture. An embodiment includes a grating having a width narrower than a width of the waveguide on which the grating is formed. In accordance with certain embodiments of the present invention, masked photolithography is employed to form narrowed gratings having a desired grating strength. In an embodiment, an optical cavity of a laser is formed with a reflector grating having a width narrower than a width of the waveguide. In another embodiment an integrated optical communication system includes one or more narrow surface corrugated gratings.
摘要翻译：用于集成光学部件的窄表面波纹光栅及其制造方法。一个实施例包括具有窄于其上形成有光栅的波导的宽度的宽度的光栅。根据本发明的某些实施例，采用掩模光刻技术来形成具有所需光栅强度的窄格栅。在一个实施例中，激光器的光腔形成有具有窄于波导宽度的宽度的反射器光栅。在另一个实施例中，集成光通信系统包括一个或多个窄波纹光栅。

10. 发明申请

US20110091218A1 BROADBAND RADIO TRANSCEIVER WITH OPTICAL TRANSFORM 有权
标题翻译：宽带无线电收发器与光学变换
公开(公告)号：US20110091218A1
公开(公告)日：2011-04-21
申请号：US12976099
申请日：2010-12-22
申请人： Evan R. Green , Mario J. Paniccia , Sean M. Koehl , Richard Jones , Guy S. Anthony
发明人： Evan R. Green , Mario J. Paniccia , Sean M. Koehl , Richard Jones , Guy S. Anthony
IPC分类号： H04B10/12 , G01J1/04
CPC分类号： H04B10/2575 , H04B1/71635 , H04B1/71637 , H04B2210/006 , H04L27/2096 , H04L27/223 , H04L27/2601
摘要： A broadband receiving apparatus includes an antenna to receive a radio signal having a plurality of modulation frequencies. An amplifier drives a laser source from the broadband radio signal to produce an optical signal having a plurality of spectral components. A diffraction grating transforms the optical signal into its spectral components. An array of photo-detectors converts the spectral components into electronic signals corresponding to the plurality of modulation frequencies. A transmitting apparatus includes an array of coherent laser emitters driven by electronic signals corresponding to a plurality of modulation frequencies to produce optical signals corresponding to a plurality of spectral components. A diffraction grating inverse transforms the spectral components into a composite optical signal. A photo-detector converts the composite optical signal into a composite electronic signal including the plurality of modulation frequencies. An amplifier amplifies the composite electronic signal for transmission as a broadband radio signal.
摘要翻译：宽带接收装置包括用于接收具有多个调制频率的无线电信号的天线。放大器从宽带无线电信号驱动激光源以产生具有多个频谱分量的光信号。衍射光栅将光信号转换成其光谱分量。光检测器阵列将光谱分量转换成对应于多个调制频率的电子信号。发送装置包括由对应于多个调制频率的电子信号驱动的相干激光发射器的阵列，以产生对应于多个频谱分量的光信号。衍射光栅将光谱分量逆变换成复合光信号。光检测器将复合光信号转换成包括多个调制频率的复合电子信号。放大器放大复合电子信号作为宽带无线电信号进行传输。

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