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1. 发明授权

US09060745B2 System and method for detecting fluid responsiveness of a patient 有权
标题翻译：用于检测患者的液体反应性的系统和方法
公开(公告)号：US09060745B2
公开(公告)日：2015-06-23
申请号：US13591455
申请日：2012-08-22
申请人： Mark Su , James Nicholas Watson , Paul Stanley Addison
发明人： Mark Su , James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B5/00 , A61B5/024 , A61B5/0245 , A61B5/026 , A61B5/1455 , A61B5/1495 , A61B6/00 , A61B8/06 , A61B5/0432 , A61B5/05
CPC分类号： A61B5/14552 , A61B5/0059 , A61B5/02007 , A61B5/0205 , A61B5/02416 , A61B5/0245 , A61B5/026 , A61B5/0261 , A61B5/0295 , A61B5/0432 , A61B5/0507 , A61B5/1495 , A61B5/4839 , A61B5/486 , A61B5/6826 , A61B5/7214 , A61B5/7225 , A61B5/7278 , A61B5/742 , A61B6/507 , A61B8/06
摘要： A system is configured to determine a fluid responsiveness index of a patient from a physiological signal. The system may include a sensor configured to be secured to an anatomical portion of the patient, and a monitor operatively connected to the sensor. The sensor is configured to sense a physiological characteristic of the patient. The monitor is configured to receive a physiological signal from the sensor. The monitor may include an index-determining module configured to determine the fluid responsiveness index through formation of a ratio of one or both of amplitude or frequency modulation of the physiological signal to baseline modulation of the physiological signal.
摘要翻译：系统被配置为从生理信号确定患者的流体反应性指数。系统可以包括被配置为固定到患者的解剖部分的传感器，以及可操作地连接到传感器的监视器。传感器被配置为感测患者的生理特征。监视器被配置成从传感器接收生理信号。监视器可以包括索引确定模块，其被配置为通过形成生理信号的幅度或频率调制与生理信号的基线调制之间的一个或两个的比率来确定流体响应性指数。

2. 发明申请

US20140058229A1 SYSTEM AND METHOD FOR DETECTING FLUID RESPONSIVENESS OF A PATIENT 有权
标题翻译：用于检测患者的流体反应的系统和方法
公开(公告)号：US20140058229A1
公开(公告)日：2014-02-27
申请号：US13591455
申请日：2012-08-22
申请人： Mark Su , James Nicholas Watson , Paul Stanley Addison
发明人： Mark Su , James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B6/00 , A61B5/1455
CPC分类号： A61B5/14552 , A61B5/0059 , A61B5/02007 , A61B5/0205 , A61B5/02416 , A61B5/0245 , A61B5/026 , A61B5/0261 , A61B5/0295 , A61B5/0432 , A61B5/0507 , A61B5/1495 , A61B5/4839 , A61B5/486 , A61B5/6826 , A61B5/7214 , A61B5/7225 , A61B5/7278 , A61B5/742 , A61B6/507 , A61B8/06
摘要： A system is configured to determine a fluid responsiveness index of a patient from a physiological signal. The system may include a sensor configured to be secured to an anatomical portion of the patient, and a monitor operatively connected to the sensor. The sensor is configured to sense a physiological characteristic of the patient. The monitor is configured to receive a physiological signal from the sensor. The monitor may include an index-determining module configured to determine the fluid responsiveness index through formation of a ratio of one or both of amplitude or frequency modulation of the physiological signal to baseline modulation of the physiological signal.
摘要翻译：系统被配置为从生理信号确定患者的流体反应性指数。系统可以包括被配置为固定到患者的解剖部分的传感器，以及可操作地连接到传感器的监视器。传感器被配置为感测患者的生理特征。监视器被配置为从传感器接收生理信号。监视器可以包括索引确定模块，其被配置为通过形成生理信号的幅度或频率调制与生理信号的基线调制之间的一个或两个的比率来确定流体响应性指数。

3. 发明申请

US20140081098A1 SENSOR SYSTEM 审中-公开
标题翻译：传感器系统
公开(公告)号：US20140081098A1
公开(公告)日：2014-03-20
申请号：US13618227
申请日：2012-09-14
申请人： Kristi Cohrs , James Nicholas Watson , Paul Stanley Addison , Mark Su
发明人： Kristi Cohrs , James Nicholas Watson , Paul Stanley Addison , Mark Su
IPC分类号： A61B5/024
CPC分类号： A61B5/02444 , A61B5/02028 , A61B5/02125 , A61B5/029 , A61B5/14552 , A61B5/6816 , A61B5/6822
摘要： A sensor system is provided for determining a pulse transit time measurement of a patient. The sensor system includes a carotid sensor device configured to be positioned on a neck of the patient over a carotid artery of the patient. The carotid sensor device is configured to detect a plethysmograph waveform from the carotid artery. The sensor system includes a temporal sensor device that is operatively connected to the carotid sensor device. The temporal sensor device is configured to be positioned on the patient over a temporal artery of the patient. The temporal sensor device is configured to detect a plethysmograph waveform from the temporal artery.
摘要翻译：提供了用于确定患者的脉搏传播时间测量的传感器系统。传感器系统包括颈动脉传感器装置，其被配置为位于患者的颈部上方位于患者的颈动脉上。颈动脉传感器装置被配置为检测来自颈动脉的体积描记器波形。传感器系统包括可操作地连接到颈动脉传感器装置的时间传感器装置。时间传感器装置被配置为在患者的颞动脉上定位在患者身上。时间传感器装置被配置为从颞动脉检测体积描记器波形。

4. 发明授权

US09301697B2 Systems and methods for recalibrating a non-invasive blood pressure monitor 有权
标题翻译：重新校准非侵入性血压计的系统和方法
公开(公告)号：US09301697B2
公开(公告)日：2016-04-05
申请号：US12242858
申请日：2008-09-30
申请人： Clark R. Baker, Jr. , James Nicholas Watson , Paul Stanley Addison
发明人： Clark R. Baker, Jr. , James Nicholas Watson , Paul Stanley Addison
IPC分类号： A61B5/02 , A61B5/021 , A61B5/022 , G06F19/00 , A61B5/1455 , A61B5/00
CPC分类号： A61B5/021 , A61B5/02125 , A61B5/022 , A61B5/02225 , A61B5/1455 , A61B5/7239 , A61B2560/0223 , G16H15/00 , G16H40/40 , G16H40/63
摘要： Techniques for non-invasive blood pressure monitoring are disclosed. Data corresponding to a patient may be received from a hospital information system. The data may include, for example, drug administration data, medical procedure data, medical equipment data, or a combination thereof. Whether a blood pressure monitoring system needs to be recalibrated may be determined, based at least in part on the received data. If it is determined that the blood pressure monitoring system needs to be recalibrated, the recalibration may be performed and at least one blood pressure measurement of the patient may be computed using the recalibrated blood pressure monitoring system.
摘要翻译：公开了用于非侵入性血压监测的技术。可以从医院信息系统接收对应于患者的数据。数据可以包括例如药物管理数据，医疗程序数据，医疗设备数据或其组合。至少部分地基于所接收的数据，可以确定是否需要重新校准血压监测系统。如果确定需要重新校准血压监测系统，则可以执行重新校准，并且可以使用重新校准的血压监测系统来计算患者的至少一个血压测量值。

5. 发明授权

US09198616B2 Method of analyzing and processing signals 有权
标题翻译：信号分析处理方法
公开(公告)号：US09198616B2
公开(公告)日：2015-12-01
申请号：US13590095
申请日：2012-08-20
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/02 , A61B5/00 , A61B5/024 , A61B5/08 , A61B5/1455 , G01N21/31
CPC分类号： A61B5/726 , A61B5/0002 , A61B5/0082 , A61B5/02416 , A61B5/02438 , A61B5/0816 , A61B5/14551 , A61B5/14552 , A61B5/4818 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6896 , A61B5/7207 , A61B5/7214 , A61B5/7278 , A61B5/7282 , A61B5/742 , A61B2503/06 , G01N21/3151 , G06F19/00
摘要： A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyze the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analog to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyzer component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyzer component.
摘要翻译：公开了一种生理测量系统，其可以从患者获取诸如光谱体积图的脉搏血氧测定信号，然后分析该信号以测量生理参数，包括呼吸，脉搏，氧饱和度和运动。该系统包括脉搏血氧计，其包括发光装置和可附接到对象的光电检测器，以获得脉搏血氧饱和度信号; 模数转换器装置，被布置成将所述脉搏血氧测定信号转换成数字脉搏血氧饱和度信号; 信号处理装置，适于接收所述数字脉搏血氧饱和度信号，并被布置成通过小波变换装置分解该信号; 特征提取装置，被布置成从分解信号中导出生理信息; 分析器组件，被布置成从特征提取装置收集信息; 以及数据输出装置，被布置成与分析器组件通信。

6. 发明授权

US09031627B2 Signal processing systems and methods using multiple signals 有权
标题翻译：信号处理系统和使用多种信号的方法
公开(公告)号：US09031627B2
公开(公告)日：2015-05-12
申请号：US12242918
申请日：2008-10-01
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/1455 , A61B5/00
CPC分类号： A61B5/726 , A61B5/14551 , A61B5/7203
摘要： According to embodiments, techniques for signal processing using multiple signals are disclosed. A first scalogram may be generated from a first signal and a second scalogram may be generated from a second signal. A modified or masked scalogram may then be generated based on the first and second scalograms. The modified scalogram may then be used to determine at least one physiological parameter. In some embodiments, one or both of the first signal and the second signal may be photoplethysmograph (PPG) signals obtained from a pulse oximeter.
摘要翻译：根据实施例，公开了使用多个信号的信号处理技术。可以从第一信号产生第一缩放图，并且可以从第二信号生成第二缩放图。然后可以基于第一和第二缩放图来生成经修改或掩蔽的缩放图。然后可以使用经修改的缩放图来确定至少一个生理参数。在一些实施例中，第一信号和第二信号中的一个或两个可以是从脉搏血氧计获得的光电体积描记术（PPG）信号。

7. 发明授权

US08483459B2 Systems and methods for ridge selection in scalograms of signals 失效
公开(公告)号：US08483459B2
公开(公告)日：2013-07-09
申请号：US13548129
申请日：2012-07-12
申请人： James Nicholas Watson , Paul Stanley Addison , David Clifton
发明人： James Nicholas Watson , Paul Stanley Addison , David Clifton
IPC分类号： G06K9/00
CPC分类号： A61B5/0806 , A61B5/0816 , A61B5/14551 , A61B5/726 , G06K9/0053
摘要： According to embodiments, systems, devices, and methods for ridge selection in scalograms are disclosed. Ridges or ridge components are features within a scalogram which may be computed from a signal such as a physiological (e.g., photoplethysmographic) signal. Ridges may be identified from one or more scalograms of the signal. Parameters characterizing these ridges may be determined. Based at least in part on these parameters, a ridge density distribution function is determined. A ridge is selected from analyzing this ridge density distribution function. In some embodiments, the selected ridge is used to determine a physiological parameter such as respiration rate.

8. 发明授权

US08478376B2 Systems and methods for determining physiological information using selective transform data 失效
标题翻译：使用选择性变换数据确定生理信息的系统和方法
公开(公告)号：US08478376B2
公开(公告)日：2013-07-02
申请号：US12512143
申请日：2009-07-30
申请人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson , Scott McGonigle
发明人： Braddon M. Van Slyke , Paul Stanley Addison , James Nicholas Watson , Scott McGonigle
IPC分类号： A61B5/1455
CPC分类号： G06K9/00516 , A61B5/02416 , A61B5/14551 , A61B5/7207 , A61B5/726
摘要： According to embodiments, a pulse band region is identified in a wavelet scalogram of a physiological signal (e.g., a plethysmograph or photoplethysmograph signal). Components of the scalogram at scales larger than the identified pulse band region are then used to determine a baseline signal in wavelet space. The baseline signal may then be used to normalize the physiological signal. Physiological information may be determined from the normalized signal. For example, oxygen saturation may be determined using a ratio of ratios or any other suitable technique.
摘要翻译：根据实施例，在生理信号（例如，体积描记器或光电体积描记信号）的小波图示中识别脉冲带区域。然后使用尺度大于识别的脉冲带区域的标尺的分量来确定小波空间中的基线信号。然后可以使用基线信号来标准化生理信号。生理信息可以从归一化信号确定。例如，氧饱和度可以使用比率或任何其它合适的技术来确定。

9. 发明申请

US20130046161A1 METHOD OF ANALYZING AND PROCESSING SIGNALS 审中-公开
公开(公告)号：US20130046161A1
公开(公告)日：2013-02-21
申请号：US13590108
申请日：2012-08-20
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/0205 , A61B5/1455
CPC分类号： A61B5/726 , A61B5/0002 , A61B5/0082 , A61B5/02416 , A61B5/02438 , A61B5/0816 , A61B5/14551 , A61B5/14552 , A61B5/4818 , A61B5/6826 , A61B5/6829 , A61B5/6838 , A61B5/6896 , A61B5/7207 , A61B5/7214 , A61B5/7278 , A61B5/7282 , A61B5/742 , A61B2503/06 , G01N21/3151
摘要： A physiological measurement system is disclosed which can take a pulse oximetry signal such as a photoplethysmogram from a patient and then analyse the signal to measure physiological parameters including respiration, pulse, oxygen saturation and movement. The system comprises a pulse oximeter which includes a light emitting device and a photodetector attachable to a subject to obtain a pulse oximetry signal; analogue to digital converter means arranged to convert said pulse oximetry signal into a digital pulse oximetry signal; signal processing means suitable to receive said digital pulse oximetry signal and arranged to decompose that signal by wavelet transform means; feature extraction means arranged to derive physiological information from the decomposed signal; an analyser component arranged to collect information from the feature extraction means; and data output means arranged in communication with the analyser component.

10. 发明申请

US20130012792A1 SYSTEMS AND METHODS FOR IDENTIFYING PULSE RATES 审中-公开
标题翻译：用于识别脉冲速率的系统和方法
公开(公告)号：US20130012792A1
公开(公告)日：2013-01-10
申请号：US13620297
申请日：2012-09-14
申请人： Paul Stanley Addison , James Nicholas Watson
发明人： Paul Stanley Addison , James Nicholas Watson
IPC分类号： A61B5/0205 , A61B5/1455
CPC分类号： A61B5/14551 , A61B5/7207 , A61B5/7225 , A61B5/7257 , A61B5/726
摘要： According to embodiments, techniques for using continuous wavelet transforms and spectral transforms to identify pulse rates from a photoplethysmographic (PPG) signal are disclosed. According to embodiments, candidate pulse rates of the PPG signal may be identified from a wavelet transformed PPG signal and a spectral transformed PPG signal. A pulse rate may be determined from the candidate pulse rates by selecting one of the candidate pulse rates or by combining the candidate pulse rates. According to embodiments, a spectral transform of a PPG signal may be performed to identify a frequency region associated with a pulse rate of the PPG signal. A continuous wavelet transform of the PPG signal at a scale corresponding to the identified frequency region may be performed to determine a pulse rate from the wavelet transformed signal.
摘要翻译：根据实施例，公开了使用连续小波变换和频谱变换来识别来自光电体积描记术（PPG）信号的脉率的技术。根据实施例，可以从小波变换的PPG信号和频谱变换的PPG信号中识别PPG信号的候选脉冲速率。可以通过选择候选脉冲速率之一或通过组合候选脉冲速率从候选脉冲速率确定脉率。根据实施例，可以执行PPG信号的频谱变换以识别与PPG信号的脉冲速率相关联的频率区域。可以执行以与所识别的频率区域对应的比例的PPG信号的连续小波变换，以从小波变换信号确定脉率。

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