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1. 发明申请

US20120165793A1 Pill Catchers 审中-公开
标题翻译：药丸捕手
公开(公告)号：US20120165793A1
公开(公告)日：2012-06-28
申请号：US12976745
申请日：2010-12-22
申请人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James T. Spivey , Michael J. Stokes , Thomas E. Albrecht , James W. Voegele , William B. Weisenburgh, II , Rudolph H. Nobis , Mark S. Zeiner , Mark D. Overmyer , Darrel M. Powell , Joseph Bernard Kraimer , James Anthony Topich , Jeremy David Jarrett , Daniel James Prenger , Matthew D. Rohr Daniel
发明人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James T. Spivey , Michael J. Stokes , Thomas E. Albrecht , James W. Voegele , William B. Weisenburgh, II , Rudolph H. Nobis , Mark S. Zeiner , Mark D. Overmyer , Darrel M. Powell , Joseph Bernard Kraimer , James Anthony Topich , Jeremy David Jarrett , Daniel James Prenger , Matthew D. Rohr Daniel
IPC分类号： A61K9/22
CPC分类号： A61M31/002 , A61B1/041
摘要： Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.
摘要翻译：提供了设备和相关方法，用于将治疗剂控制递送到身体内的目标位置。更具体地，提供了用于控制经口给药的药丸通过身体的速率的方法和装置，以及用于控制体内在特定位置处的丸剂内的治疗剂的递送。提供了在本文中通常被称为“捕获器”的各种类型的装置，其可以在通过身体时主动地捕捉药丸。捕获器可以将药丸保持在体内的特定位置，直到发生预定事件，例如在丸中部分或完全施用治疗剂。然后，捕手可以在命令和/或发生预定事件时释放药片以允许药丸从身体中流出。在其他实施例中，提供了可以主动地接合捕获器并保持与捕获器接合的各种类型的药丸，直到发生预定事件。

2. 发明申请

US20120165792A1 Pill Catchers 审中-公开
标题翻译：药丸捕手
公开(公告)号：US20120165792A1
公开(公告)日：2012-06-28
申请号：US12976648
申请日：2010-12-22
申请人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James T. Spivey , Michael J. Stokes , Thomas E. Albrecht , Mark S. Zeiner , Joseph Bernard Kraimer , James Anthony Topich , Daniel James Prenger
发明人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James T. Spivey , Michael J. Stokes , Thomas E. Albrecht , Mark S. Zeiner , Joseph Bernard Kraimer , James Anthony Topich , Daniel James Prenger
IPC分类号： A61M37/00
CPC分类号： A61M31/002 , A61B1/00147 , A61B1/041 , A61B5/07 , A61B5/4839
摘要： Devices and related methods arc provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete. administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.
摘要翻译：提供了设备和相关方法，用于将治疗剂控制递送到身体内的目标位置。更具体地，提供了用于控制经口给药的药丸通过身体的速率的方法和装置，以及用于控制体内在特定位置处的丸剂内的治疗剂的递送。提供了在本文中通常被称为“捕获器”的各种类型的装置，其可以在通过身体时主动地捕捉药丸。捕手可以将药丸保持在身体内的特定位置，直到发生预定事件，例如部分或完全。给药丸内的治疗剂。然后，捕手可以在命令和/或发生预定事件时释放药片以允许药丸从身体中流出。在其他实施例中，提供了可以主动地接合捕获器并保持与捕获器接合的各种类型的药丸，直到发生预定事件。

3. 发明申请

US20090275964A1 METHOD OF ROLLING STOMACH TISSUE SO AS TO MAXIMIZE THE CONTACT SURFACE AREA OF A FOLD 审中-公开
标题翻译：滚动组织的方法，以便最大限度地减少接触面的面积
公开(公告)号：US20090275964A1
公开(公告)日：2009-11-05
申请号：US12113773
申请日：2008-05-01
申请人： Mark S. Zeiner , Jason L. Harris , Michael J. Stokes , Daniel E. Alesi , Mark S. Ortiz , Thomas E. Albrecht , James T. Spivey , Lawrence Crainich
发明人： Mark S. Zeiner , Jason L. Harris , Michael J. Stokes , Daniel E. Alesi , Mark S. Ortiz , Thomas E. Albrecht , James T. Spivey , Lawrence Crainich
IPC分类号： A61B17/12 , A61B17/34
CPC分类号： A61B17/00234 , A61B2017/00827 , A61B2017/00867 , A61B2017/0649 , A61B2017/081 , A61B2017/2926 , A61F5/0086
摘要： A rolling instrument for rolling the outside surface of the stomach for reducing stomach volume in bariatric surgery includes an elongated tubular body that is sufficiently flexible to allow for access to the outside surface. The tubular body includes a proximal end and a distal end. The proximal end is shaped and dimensioned for use by the medical practitioner performing the medical procedure and includes a handle for manipulation of the rolling instrument. The distal end of the tubular body includes a mechanism allowing for gripping of the stomach in a manner permitting rolling thereof. A coiled retainer shaped and dimensioned is provided for application to the rolled portion of the stomach in a manner holding the rolled portion of the stomach in its rolled configuration. The coiled retainer includes a helically coiled body having a first end and a second end, the first end is pointed such that it may puncture tissue as the coiled body is rotated during its application to the stomach.
摘要翻译：用于在减肥手术中滚动用于减少胃体积的胃的外表面的滚动仪器包括具有足够柔性以允许进入外表面的细长管状体。管状体包括近端和远端。近端的形状和尺寸被医生执行医疗程序所使用，并且包括用于操纵滚动仪器的手柄。管状体的远端包括允许以允许其滚动的方式夹持胃的机构。提供成形和尺寸的盘形保持器，以使其处于卷成形状的胃的卷绕部分的方式施加到胃的卷绕部分。卷绕的保持器包括具有第一端和第二端的螺旋状卷绕体，第一端是尖的，使得当线圈体在其施加到胃部期间旋转时可能刺穿组织。

4. 发明授权

US07967741B2 Endoscopic guide device 有权
标题翻译：内镜引导装置
公开(公告)号：US07967741B2
公开(公告)日：2011-06-28
申请号：US11742948
申请日：2007-05-01
申请人： Gregory J. Bakos , Christie M. Cunningham , David Stefanchik , James W. Voegele , Michael J. Stokes , Christopher J. Hess , James T. Spivey , Gary L. Long , Kurt R. Bally , Ragae M. Ghabrial , Rudolph H. Nobis
发明人： Gregory J. Bakos , Christie M. Cunningham , David Stefanchik , James W. Voegele , Michael J. Stokes , Christopher J. Hess , James T. Spivey , Gary L. Long , Kurt R. Bally , Ragae M. Ghabrial , Rudolph H. Nobis
IPC分类号： A61B1/00 , A61F2/00 , A61F13/00 , A61M5/32
CPC分类号： A61B1/01 , A61B1/00147 , A61B5/6882 , A61B17/0401 , A61B2017/00292 , A61B2017/00336
摘要： Various exemplary methods and devices are provided for manipulating and/or anchoring devices and body parts during surgical procedures. In one embodiment, an anchor member is provided for anchoring a device or body part to tissue, such as an internal wall of a body cavity. The device can be, for example, an endoscopic device, an accessory channel coupled to an endoscopic device, or a support member adapted to support or manipulate an organ. The anchor member can include or form an opening through which the device can be inserted. The anchor member or device can thus be manipulated relative to the tissue to control movement of and/or provide support to the device, tools inserted through the device, and/or organs grasped by the device or tools.
摘要翻译：提供各种示例性的方法和装置用于在外科手术过程中操纵和/或锚定装置和身体部位。在一个实施例中，提供锚定构件用于将装置或身体部分锚定到组织，例如体腔的内壁。该装置可以是例如内窥镜装置，耦合到内窥镜装置的附件通道或适于支撑或操纵器官的支撑构件。锚定构件可以包括或形成开口，通过该开口可以插入装置。锚定构件或装置因此可以相对于组织被操纵以控制装置的移动和/或提供对装置的插入，通过装置插入的工具和/或由装置或工具抓住的器官。

5. 发明申请

US20080275297A1 ENDOSCOPIC GUIDE DEVICE 有权
标题翻译：内窥镜指导装置
公开(公告)号：US20080275297A1
公开(公告)日：2008-11-06
申请号：US11742948
申请日：2007-05-01
申请人： Gregory J. Bakos , Christie M. Cunningham , David Stefanchik , James W. Voegele , Michael J. Stokes , Christopher J. Hess , James T. Spivey , Gary L. Long , Kurt R. Bally , Ragae M. Ghabrial , Rudolph H. Nobis
发明人： Gregory J. Bakos , Christie M. Cunningham , David Stefanchik , James W. Voegele , Michael J. Stokes , Christopher J. Hess , James T. Spivey , Gary L. Long , Kurt R. Bally , Ragae M. Ghabrial , Rudolph H. Nobis
IPC分类号： A61B1/00
CPC分类号： A61B1/01 , A61B1/00147 , A61B5/6882 , A61B17/0401 , A61B2017/00292 , A61B2017/00336
摘要： Various exemplary methods and devices are provided for manipulating and/or anchoring devices and body parts during surgical procedures. In one embodiment, an anchor member is provided for anchoring a device or body part to tissue, such as an internal wall of a body cavity. The device can be, for example, an endoscopic device, an accessory channel coupled to an endoscopic device, or a support member adapted to support or manipulate an organ. The anchor member can include or form an opening through which the device can be inserted. The anchor member or device can thus be manipulated relative to the tissue to control movement of and/or provide support to the device, tools inserted through the device, and/or organs grasped by the device or tools.
摘要翻译：提供各种示例性的方法和装置用于在外科手术过程中操纵和/或锚定装置和身体部位。在一个实施例中，提供锚定构件用于将装置或身体部分锚定到组织，例如体腔的内壁。该装置可以是例如内窥镜装置，耦合到内窥镜装置的附件通道或适于支撑或操纵器官的支撑构件。锚定构件可以包括或形成开口，通过该开口可以插入装置。锚定构件或装置因此可以相对于组织被操纵以控制装置的移动和/或提供对装置的插入，通过装置插入的工具和/或由装置或工具抓住的器官。

6. 发明申请

US20090275980A1 METHOD AND APPARATUS FOR THE FORMATION OF TISSUE FOLDS 审中-公开
标题翻译：组织形成的方法和装置
公开(公告)号：US20090275980A1
公开(公告)日：2009-11-05
申请号：US12113633
申请日：2008-05-01
申请人： Mark S. Zeiner , Michael J. Stokes , Jason L. Harris , Wayne Young , James T. Spivey
发明人： Mark S. Zeiner , Michael J. Stokes , Jason L. Harris , Wayne Young , James T. Spivey
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B2017/0417 , A61F5/0086
摘要： A suture anchoring device includes a fastener body composed of a tube and a spool is mounted within the tube for rotation relative to the tube. Suture material is wrapped about the spool such that pulling of the suture material causes rotation of the spool within the tube. A one-way locking mechanism allows the spool to rotate freely in a first direction and prevents rotation in an opposite direction. A method for creating a tissue fold includes deploying a first suture anchoring device within the tissue with suture material extending proximally from the first suture anchoring device, deploying a second suture anchoring device within the tissue with a distal portion of the suture material extending between the first suture anchoring device and a proximal portion of the suture material extending proximally from the second suture anchoring device, and applying tension to the suture material to draw portions of the tissue together to form a tissue fold.
摘要翻译：缝合线锚定装置包括由管组成的紧固件主体，并且线轴安装在管内以相对于管旋转。缝线材料缠绕在线轴上，使得缝合材料的拉动导致线轴在管内旋转。单向锁定机构允许线轴在第一方向上自由旋转并且防止沿相反方向旋转。用于产生组织折叠的方法包括使用从第一缝合线锚定装置向近侧延伸的缝合材料在组织内展开第一缝合线锚定装置，在组织内部展开第二缝合线锚固装置，其中缝合材料的远端部分在第一缝合线锚定装置和缝合材料的近端部分从第二缝合线锚定装置向近侧延伸，并且向缝合材料施加张力以将组织的部分拉到一起以形成组织折叠。

7. 发明申请

US20090192344A1 SURGICAL DEVICES FOR MANIPULATING TISSUE 审中-公开
标题翻译：用于手术组织的外科手术
公开(公告)号：US20090192344A1
公开(公告)日：2009-07-30
申请号：US12019461
申请日：2008-01-24
申请人： Gregory J. Bakos , Christie Mrie Cunningham , Kendall Lee Dobler , William D. Fox , Christopher J. Hess , Gary L. Long , Rudolph Henry Nobis , Carl J. Shurtleff , James T. Spivey , David Stefanchik , Michael J. Stokes , Omar J. Vakharia , James W. Voegele
发明人： Gregory J. Bakos , Christie Mrie Cunningham , Kendall Lee Dobler , William D. Fox , Christopher J. Hess , Gary L. Long , Rudolph Henry Nobis , Carl J. Shurtleff , James T. Spivey , David Stefanchik , Michael J. Stokes , Omar J. Vakharia , James W. Voegele
IPC分类号： A61N2/10 , A61N2/00
CPC分类号： A61B17/0218 , A61B17/0401 , A61B17/30 , A61B17/3478 , A61B34/73 , A61B2017/00876 , A61B2017/0464 , A61B2017/2926 , A61B2017/306
摘要： A surgical kit can be used to manipulate tissue within the body of a patient to create a working space within the body to allow a surgeon to easily access and work within the body using various surgical instruments. A surgical kit can include an implant comprised of a magnetic material which can be engaged with tissue within the body. The kit can further include a surgical instrument having a magnet which can be used to manipulate the implant and tissue engaged therewith. A surgical kit can include an anchor and a hanger configured to engage tissue at different locations within the body and a connection member engaged with the anchor and the hanger such that the connection member can be pulled to move the anchor toward the hanger. A surgical instrument which utilizes a vacuum provided to one or more movable members can also be used to manipulate tissue.
摘要翻译：手术套件可用于操纵患者身体内的组织以在身体内产生工作空间，以允许外科医生使用各种手术器械容易地进入身体内并进行工作。手术套件可以包括由可与身体内的组织接合的磁性材料构成的植入物。该套件还可以包括具有磁体的手术器械，其可用于操纵植入物和与其接合的组织。手术套件可以包括锚固件和悬挂器，其构造成在主体内的不同位置处接合组织，以及与锚固件和悬挂器接合的连接构件，使得连接构件可以被拉动以将锚移向吊架。使用提供给一个或多个可移动部件的真空的手术器械也可用于操纵组织。

8. 发明申请

US20130085341A1 METHODS AND DEVICES FOR MANIPULATING TISSUE IN VIVO 审中-公开
标题翻译：用于在体液中操作组织的方法和装置
公开(公告)号：US20130085341A1
公开(公告)日：2013-04-04
申请号：US13249896
申请日：2011-09-30
申请人： Rudolph H. Nobis , Robert M. Trusty , James T. Spivey , Christopher J. Hess , Per O. Park , Omar J. Vakharia
发明人： Rudolph H. Nobis , Robert M. Trusty , James T. Spivey , Christopher J. Hess , Per O. Park , Omar J. Vakharia
IPC分类号： A61B1/32 , A61B17/34
CPC分类号： A61B17/29 , A61B17/07207 , A61B2017/00473 , A61B2017/00477
摘要： Methods and devices are provided for manipulating tissue in a body cavity, i.e., in vivo. In general, the methods and devices allow an end effector to engage tissue, be detached from a shaft used to control the end effector to engage the tissue, and then be moved to another location in the body cavity by a separate component, such as an external control unit. In some embodiments the end effector can include one or more deployable hooks that allow the end effector to remain at a surgical site independent of any shafts or external control units. Still further, in other embodiments the end effector can include a transverse bore to allow a second shaft to connect to the end effector to manipulate the tissue. Additional exemplary devices, kits, and methods related to manipulating tissue in vivo are also provided.
摘要翻译：提供了用于操作体腔中的组织，即体内的方法和装置。通常，方法和装置允许端部执行器接合组织，从用于控制末端执行器的轴分离以接合组织，然后通过单独的部件移动到体腔中的另一位置，例如外部控制单元。在一些实施例中，末端执行器可以包括一个或多个可展开的钩，其允许端部执行器独立于任何轴或外部控制单元而保持在手术位置。此外，在其他实施例中，端部执行器可以包括横向孔，以允许第二轴连接到末端执行器以操纵组织。还提供了与在体内操作组织相关的附加的示例性装置，试剂盒和方法。

9. 发明申请

US20110087265A1 LAPAROSCOPIC INSTRUMENT WITH ATTACHABLE END EFFECTOR 审中-公开
标题翻译：具有附加功能的LAPAROSCOPIC仪器
公开(公告)号：US20110087265A1
公开(公告)日：2011-04-14
申请号：US12576546
申请日：2009-10-09
申请人： Rudolph H. Nobis , James T. Spivey , Kevin M. Huey , Christopher J. Hess
发明人： Rudolph H. Nobis , James T. Spivey , Kevin M. Huey , Christopher J. Hess
IPC分类号： A61B17/28
CPC分类号： A61B17/29 , A61B17/320016 , A61B2017/00362 , A61B2017/00473 , A61B2017/00477 , A61B2017/0053 , A61B2017/2931 , A61B2017/320093 , A61B2017/320095
摘要： A laparoscopic surgical device comprises an elongate shaft defining a longitudinal axis, the shaft comprising a distal end and a proximal end. A plurality of arms project distally from the distal end of the elongate shaft, the arms each comprising a lateral notch. The arms are axially slideable relative the elongate shaft and are medially deflectable. An elongate pin is positioned medially relative the arms. The elongate pin is axially slideable relative the arms between a locked position preventing medial deflection of the arms and an unlocked position allowing medial deflection of the arms. A surgical end effector is selectively attachable in vivo and detachable in vivo to the mating feature of the arms, the surgical end effector comprising jaws that open and close in response to the axial movement of the two arms when attached to the surgical end effector.
摘要翻译：腹腔镜手术装置包括限定纵向轴线的细长轴，该轴包括远端和近端。多个臂从细长轴的远端向远侧突出，所述臂各自包括侧向凹口。臂相对于细长轴可轴向滑动并且可内向偏转。细长销相对于臂中间定位。细长销相对于臂在可防止臂的内侧偏转的锁定位置和允许臂的内侧偏转的解锁位置之间轴向滑动。手术末端执行器可选择性地附接到体内并且能够在体内可拆卸到臂的配合特征，所述外科末端执行器包括当连接到手术端部执行器时响应于两个臂的轴向运动而打开和关闭的钳口。

10. 发明申请

US20120078291A1 LAPAROSCOPIC INSTRUMENT WITH ATTACHABLE END EFFECTOR 审中-公开
公开(公告)号：US20120078291A1
公开(公告)日：2012-03-29
申请号：US12889458
申请日：2010-09-24
申请人： Rudolph H. NOBIS , James T. Spivey , Christopher J. Hess , Kevin M. Huey
发明人： Rudolph H. NOBIS , James T. Spivey , Christopher J. Hess , Kevin M. Huey
IPC分类号： A61B17/28
CPC分类号： A61B17/29 , A61B2017/00362 , A61B2017/00477 , A61B2017/2931 , A61B2017/294 , A61B2017/2946 , A61B2017/3454
摘要： A laparoscopic surgical device comprises an elongate shaft defining a longitudinal axis, the shaft comprising a distal end and a proximal end. A plurality of arms project distally from the distal end of the elongate shaft, the arms each comprising a lateral notch. The arms are axially slideable relative the elongate shaft and are medially deflectable. An elongate pin is positioned medially relative the arms. The elongate pin is axially slideable relative the arms between a locked position preventing medial deflection of the arms and an unlocked position allowing medial deflection of the arms. A surgical end effector is selectively attachable in vivo and detachable in vivo to the mating feature of the arms, the surgical end effector comprising a torque transfer means and tissue contact apparatus that open and close in response to the axial movement of the two arms when attached to the surgical end effector.

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