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1. 发明申请

US20070141178A1 Processes for Obtaining Lignan Extracts and Compositions Containing the Lignan Extracts 审中-公开
标题翻译：获得含有木质素提取物的木质素提取物和组合物的方法
公开(公告)号：US20070141178A1
公开(公告)日：2007-06-21
申请号：US11566356
申请日：2006-12-04
申请人： Mark Empie , William Fletcher , Thomas Gottemoller , Richard Grabiel , Lawrence Karcher , Sigmund Peterson , Sam Sun
发明人： Mark Empie , William Fletcher , Thomas Gottemoller , Richard Grabiel , Lawrence Karcher , Sigmund Peterson , Sam Sun
IPC分类号： A61K31/704
CPC分类号： C07H1/08 , A61K31/7034 , A61K31/704 , A61K36/15 , A61K36/736 , A61K36/889 , A61K2300/00
摘要： Processes for obtaining lignan extracts from plant materials are disclosed. Compositions including lignan extracts as well as uses of the lignan extracts are also disclosed.
摘要翻译：公开了从植物材料获得木酚素提取物的方法。还公开了包括木酚素提取物的组合物以及木脂素提取物的用途。

2. 发明申请

US20060234948A1 Lignan-containing compositions 审中-公开
标题翻译：含木素的组合物
公开(公告)号：US20060234948A1
公开(公告)日：2006-10-19
申请号：US11397239
申请日：2006-04-03
申请人： Mark Empie , Brent Flickinger , Sam Sun
发明人： Mark Empie , Brent Flickinger , Sam Sun
IPC分类号： A61K31/7048 , A61K31/7008 , A61K31/355 , A61K31/353 , A61K31/12
CPC分类号： A61K31/353 , A23L33/105 , A23L33/11 , A23L33/15 , A23L33/22 , A23V2002/00 , A61K31/122 , A61K31/355 , A61K31/726 , A61K36/48 , A61K36/55 , A61K2300/00 , A23V2250/21172 , A23V2250/642 , A23V2250/2136
摘要： Compositions are provided that includes a lignan, and an additional compound such as an isoflavone, a tocopherol, a phytosterol, a polyphenol, a catechin, an anthocyanin, an astaxanthin, or a glucosamine. The compositions can be formulated as a dietary supplement, in tablet, powder or liquid form, or can be incorporated into a food product. Methods of treating various diseases by administering the compositions are also provided.
摘要翻译：提供了包含木酚素和另外的化合物如异黄酮，生育酚，植物甾醇，多酚，儿茶素，花青素，虾青素或葡糖胺的组合物。组合物可以配制成片剂，粉末或液体形式的膳食补充剂，或可以掺入食品中。还提供了通过施用组合物治疗各种疾病的方法。

3. 发明授权

US06399072B1 Method of preparing and using isoflavones for the treatment of alcoholism 失效
标题翻译：制备和使用异黄酮治疗酒精中毒的方法
公开(公告)号：US06399072B1
公开(公告)日：2002-06-04
申请号：US09615152
申请日：2000-07-13
申请人： Mark Empie , Eric Gugger
发明人： Mark Empie , Eric Gugger
IPC分类号： A01N6500
CPC分类号： C07D311/36 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/185 , A61K36/48 , A61K36/488 , A61K36/55 , A61K36/68 , A61K36/82 , A61K36/899 , Y10S514/823 , Y10S514/824 , Y10S514/874 , Y10S514/899 , Y10S514/923 , A61K2300/00 , A23V2250/2116 , A23V2250/2132
摘要： A composition is prepared by extracting phytochemicals from plant matter for treatment of alcohol dependency. This composition is enriched preferably with two or more fractions of plant matter, namely: isoflavones, lignans, saponins, sapogenins, catechins and phenolic acids. Soy is the preferred source of these chemicals; however, other plants may also be used, such as wheat, psyllium, rice, oats, red clover, kudzu, alfalfa, flax, and cocoa. The composition is a dietary supplement for treatment of alcoholism. The isoflavone may be any in a group including malonyl, acetyl, glucoside, and aglycone. The composition is in a concentrated form to be delivered in an easy to consume dosage, such as a pill, tablet, liquid, capsule, or a food supplement including a health bars.
摘要翻译：通过从植物物质中提取植物化学物质来处理酒精依赖性来制备组合物。该组合物优选富含植物物质的两个或更多个部分，即异黄酮，木脂素，皂角苷，皂草苷，儿茶素和酚酸。大豆是这些化学品的首选来源; 然而，也可以使用其它植物，例如小麦，欧车前，大米，燕麦，红三叶草，葛，苜蓿，亚麻和可可。该组合物是用于治疗酒精中毒的膳食补充剂。异黄酮可以是包括丙二酰基，乙酰基，葡糖苷和糖苷配基在内的任何一种。组合物为浓缩形式，以易于消耗的剂量递送，例如丸剂，片剂，液体，胶囊或包括健康酒吧的食品补充剂。

4. 发明授权

US06391310B1 Method of preparing and using isoflavones for the treatment of neurological symptoms 失效
标题翻译：制备和使用异黄酮治疗神经症状的方法
公开(公告)号：US06391310B1
公开(公告)日：2002-05-21
申请号：US09616205
申请日：2000-07-13
申请人： Mark Empie , Eric Gugger
发明人： Mark Empie , Eric Gugger
IPC分类号： A01N6500
CPC分类号： C07D311/36 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/185 , A61K36/48 , A61K36/488 , A61K36/55 , A61K36/68 , A61K36/899 , Y10S514/879 , A61K2300/00 , A23V2250/2116 , A23V2250/2132
摘要： A composition is prepared by extracting phytochemicals from plant matter and is administered to provide treatment for mental conditions and nerve problems, especially neurological symptoms, immunological symptoms, migraine headaches, inflammations and dementia. This composition is enriched preferably with two or more fractions of plant matter, namely: isoflavones, lignans, saponins, sapogenins, catechins and phenolic acids. The isoflavones are taken from a group including malonyl, acetyl, glucoside and aglycone. Soy is the preferred source of these chemicals; however, other plants may also be used, such as wheat, psyllium, rice, oats, red clover, kudzu, alfalfa, flax, and cocoa. The composition is a dietary supplement for treatment of various syndromes and disorders presented in a concentrated, easily delivered and consumed dosage, such as a health bar.
摘要翻译：通过从植物物质提取植物化学物质来制备组合物，并且被施用以提供精神状况和神经问题的治疗，特别是神经症状，免疫症状，偏头痛，炎症和痴呆。该组合物优选富含植物物质的两个或更多个部分，即异黄酮，木脂素，皂角苷，皂草苷，儿茶素和酚酸。异黄酮取自包括丙二酰，乙酰，葡糖苷和糖苷配基的组。大豆是这些化学品的首选来源; 然而，也可以使用其它植物，例如小麦，欧车前，大米，燕麦，红三叶草，葛，苜蓿，亚麻和可可。该组合物是用于治疗以浓缩，容易递送和消耗的剂量（例如健康酒吧）呈现的各种综合征和病症的膳食补充剂。

5. 发明授权

US06509381B2 Method of preparing and using compositions extracted from vegetable matter for the treatment of neurological conditions 失效
标题翻译：制备和使用从植物物质提取的组合物用于治疗神经病症的方法
公开(公告)号：US06509381B2
公开(公告)日：2003-01-21
申请号：US10136158
申请日：2002-05-01
申请人： Mark Empie , Eric Gugger
发明人： Mark Empie , Eric Gugger
IPC分类号： A01N6500
CPC分类号： C07D311/36 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/185 , A61K36/48 , A61K36/488 , A61K36/55 , A61K36/68 , A61K36/899 , Y10S514/879 , A61K2300/00 , A23V2250/2116 , A23V2250/2132
摘要： A composition is prepared by extracting and isolating phytochemical fractions from plant matter for treatment for neurological conditions and especially for migraine headaches, inflammations, dementia, and Alzheimer's Disease. The composition is enriched, preferably with two or more different fractions, namely: isoflavones, lignans, saponins and saponogenins, catechins, and phenolic acids. The two selected fractions are different from each other and are combined specifically to form a composition to treat a neurological condition. Soy is the preferred source of these phytochemicals; however, other plants may also be used, such as wheat, psyllium, rice, oats, red clover, kudzu, alfalfa, flax, and cocoa. The composition may be delivered in an easy to use or consume form, such as cream, pills, tablets, capsules, pellets, dry powder, health bars, food ingredients and supplements, soft gels, and the like.
摘要翻译：通过从植物物质提取和分离植物化学级分以治疗神经病症，特别是偏头痛，炎症，痴呆和阿尔茨海默氏病，制备组合物。该组合物富集，优选具有两种或更多种不同的级分，即：异黄酮，木脂素，皂角苷和皂角蛋白，儿茶素和酚酸。两种选择的级分彼此不同，并且特异性组合以形成治疗神经病症的组合物。大豆是这些植物化学物质的首选来源; 然而，也可以使用其它植物，例如小麦，欧车前，大米，燕麦，红三叶草，葛，苜蓿，亚麻和可可。组合物可以以易于使用或消费的形式递送，例如奶油，丸剂，片剂，胶囊，丸剂，干粉，健康酒吧，食品成分和补充剂，软凝胶等。

6. 发明授权

US06391308B1 Method of preparing and using isoflavones for the treatment of blood related illnesses 失效
标题翻译：制备和使用异黄酮治疗血液相关疾病的方法
公开(公告)号：US06391308B1
公开(公告)日：2002-05-21
申请号：US09615239
申请日：2000-07-13
申请人： Mark Empie , Eric Gugger
发明人： Mark Empie , Eric Gugger
IPC分类号： A01N6500
CPC分类号： C07D311/36 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/185 , A61K36/48 , A61K36/488 , A61K36/55 , A61K36/68 , A61K36/82 , A61K36/899 , Y10S514/823 , Y10S514/824 , Y10S514/874 , Y10S514/899 , Y10S514/923 , A61K2300/00 , A23V2250/2116 , A23V2250/2132
摘要： A composition is prepared by extracting phytochemicals from plant matter and is administered to provide treatment for cardiovascular medical conditions, such as: excessive bloodstream cholesterol, the risk of heart disease, abnormal blood lipid profiles, and abnormal vascular effects. This composition is enriched preferably with two or more fractions of plant matter, namely: isoflavones, lignans, saponins, sapogenins, catechins and phenolic acids. The isoflavones are selected from a group including malonyl, acetyl, glucoside and aglycone. Soy is the preferred source of these chemicals; however, other plants may also be used, such as wheat, psyllium, rice, oats, red clover, kudzu, alfalfa, flax, and cocoa. The composition is a dietary supplement in a concentrated form, preferably in an easy to consume form, for treatment of various cardiovascular conditions and various other related disorders.
摘要翻译：通过从植物物质提取植物化学物质来制备组合物，并施用以提供心血管医学病症的治疗，例如：血液过度胆固醇，心脏病的风险，血脂异常和血管异常异常。该组合物优选富含植物物质的两个或更多个部分，即异黄酮，木脂素，皂角苷，皂草苷，儿茶素和酚酸。异黄酮选自包括丙二酰，乙酰，葡糖苷和糖苷配基的组。大豆是这些化学品的首选来源; 然而，也可以使用其它植物，例如小麦，欧车前，大米，燕麦，红三叶草，葛，苜蓿，亚麻和可可。该组合物是浓缩形式的膳食补充剂，优选易于消费形式，用于治疗各种心血管疾病和各种其它相关疾病。

7. 发明授权

US06900240B2 Method of preparing and using compositions extracted from vegetable matter for the treatment of cancer 失效
标题翻译：制备和使用从植物物质提取的组合物用于治疗癌症的方法
公开(公告)号：US06900240B2
公开(公告)日：2005-05-31
申请号：US10137490
申请日：2002-05-01
申请人： Mark Empie , Eric Gugger
发明人： Mark Empie , Eric Gugger
IPC分类号： A61K31/7042 , A23L1/30 , A23L1/304 , A61K31/00 , A61K31/704 , A61K31/7048 , A61K36/00 , A61K36/18 , A61K36/185 , A61K36/48 , A61K36/488 , A61K36/55 , A61K36/68 , A61K36/82 , A61K36/899 , A61P15/00 , A61P15/02 , A61P19/00 , A61P19/10 , A61P25/20 , C07D311/36 , A61K35/84 , A01N65/00
CPC分类号： C07D311/36 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/185 , A61K36/48 , A61K36/488 , A61K36/55 , A61K36/68 , A61K36/82 , A61K36/899 , Y10S514/823 , Y10S514/824 , Y10S514/874 , Y10S514/899 , Y10S514/923 , A61K2300/00 , A23V2250/2116 , A23V2250/2132
摘要： A composition is prepared by extracting and isolating phytochemical fractions from plant matter for treatment of cancer and especially for breast, prostate, skin, colon, urinary and bladder cancer. The composition is enriched preferably with two or more different phytochemical fractions, namely, isoflavones, lignans, saponins and saponogenins, catechins, and phenolic acids. The two selected fractions are different from each other and are combined specifically to form a composition to treat cancer. Soy is the preferred source of these phytochemicals; however, other plants may also be used, such as wheat, psyllium, rice, oats, red clover, kudzu, alfalfa, flax, and cocoa. The composition may be delivered in an easy to use or consume form, such as creams, pills, tablets, capsules, dry powder, health bars, food ingredients and supplements, tablets, soft gels, and the like.
摘要翻译：通过从植物物质中提取和分离植物化学级分来治疗癌症，特别是对于乳腺癌，前列腺癌，皮肤癌，结肠癌，膀胱癌和癌症，制备组合物。组合物优选用两种或更多种不同的植物化学级分富集，即异黄酮，木脂素，皂苷和皂角蛋白，儿茶素和酚酸。两个选择的级分彼此不同，并且特异性组合以形成治疗癌症的组合物。大豆是这些植物化学物质的首选来源; 然而，也可以使用其它植物，例如小麦，欧车前，大米，燕麦，红三叶草，葛，苜蓿，亚麻和可可。组合物可以以易于使用或消费形式递送，例如霜剂，丸剂，片剂，胶囊，丸剂，干粉，健康酒吧，食品成分和补品，片剂，软凝胶等。

8. 发明授权

US06395279B1 Method of preparing and using isoflavones for the treatment of cancer 失效
标题翻译：制备和使用异黄酮治疗癌症的方法
公开(公告)号：US06395279B1
公开(公告)日：2002-05-28
申请号：US09616150
申请日：2000-07-13
申请人： Mark Empie , Eric Gugger
发明人： Mark Empie , Eric Gugger
IPC分类号： A01N6500
CPC分类号： C07D311/36 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/185 , A61K36/48 , A61K36/488 , A61K36/55 , A61K36/68 , A61K36/82 , A61K36/899 , Y10S514/823 , Y10S514/824 , Y10S514/874 , Y10S514/899 , Y10S514/923 , A61K2300/00 , A23V2250/2116 , A23V2250/2132
摘要： A composition is prepared by extracting phytochemicals from plant matter and is administered to provide treatment for cancer and especially for breast, prostate, skin, colon, urinary and bladder cancer. This composition is enriched preferably with two or more fractions of phytochemicals refined from plant matter, namely: isoflavones, lignans, saponins, sapogenins, catechins and phenolic acids. The isoflavones are selected from a group including malonyl, acetyl, glucoside, and aglycone. Soy is the preferred source of these chemicals; however, other plants may also be used, such as wheat, psyllium, rice, oats, red clover, kudzu, alfalfa, flax, and cocoa. The composition is a dietary supplement for treatment of various cancers and other syndromes and disorders. In particular, the dietary supplement is in a concentrated, easy to use or consume form, such as creams, pills, tablets, capsules, pellets, dry powder, health bars, food ingredients and supplements, tablets, soft gels, and the like.
摘要翻译：通过从植物物质提取植物化学物质来制备组合物，并施用以提供癌症治疗，特别是对于乳腺癌，前列腺癌，皮肤癌，结肠癌，膀胱癌和膀胱癌。该组合物优选地富含从植物物质精制的两种或更多种植物化学成分，即异黄酮，木脂素，皂角苷，皂甙元，儿茶素和酚酸。异黄酮选自丙二酰，乙酰，葡萄糖苷和糖苷配基。大豆是这些化学品的首选来源; 然而，也可以使用其它植物，例如小麦，欧车前，大米，燕麦，红三叶草，葛，苜蓿，亚麻和可可。该组合物是用于治疗各种癌症和其他综合征和障碍的膳食补充剂。特别地，膳食补充剂是浓缩的，易于使用或消费的形式，例如霜剂，丸剂，片剂，胶囊，丸剂，干粉，健康酒吧，食品成分和补品，片剂，软凝胶等。

9. 发明授权

US06391309B1 Method of preparing and using isoflavones for the treatment of female symptoms 有权
标题翻译：制备和使用异黄酮治疗女性症状的方法
公开(公告)号：US06391309B1
公开(公告)日：2002-05-21
申请号：US09615240
申请日：2000-07-13
申请人： Mark Empie , Eric Gugger
发明人： Mark Empie , Eric Gugger
IPC分类号： A01N6500
CPC分类号： C07D311/36 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/185 , A61K36/48 , A61K36/488 , A61K36/55 , A61K36/68 , A61K36/82 , A61K36/899 , Y10S514/823 , Y10S514/824 , Y10S514/874 , Y10S514/899 , Y10S514/923 , A61K2300/00 , A23V2250/2116 , A23V2250/2132
摘要： A composition is prepared by extracting phytochemicals from plant matter to form a dietary supplement for treatment of female symptoms. This composition is enriched preferably with two or more fractions of plant matter, namely: isoflavones, lignans, saponins, sapogenins, catechins and phenolic acids. Soy is the preferred source of these chemicals; however, other plants may also be used, such as wheat, psyllium, rice, oats, red clover, kudzu, alfalfa, flax, and cocoa. The isoflavone may be any in a group including malonyl, acetyl, glucoside, and aglycone. The composition is in a concentrated form to be delivered in an easy to consume dosage, such as a pill, tablet, liquid, capsule, or a food supplement including health bars. Most commonly, these female symptoms are hot flashes, osteoporosis, sleep disorders, menopausal symptoms, vaginal dryness, premenstrual syndrome, or other problems relating to a reduction of sex hormones and to menstruation.
摘要翻译：通过从植物物质提取植物化学物质形成用于治疗女性症状的膳食补充剂来制备组合物。该组合物优选富含植物物质的两个或更多个部分，即异黄酮，木脂素，皂角苷，皂草苷，儿茶素和酚酸。大豆是这些化学品的首选来源; 然而，也可以使用其它植物，例如小麦，欧车前，大米，燕麦，红三叶草，葛，苜蓿，亚麻和可可。异黄酮可以是包括丙二酰基，乙酰基，葡糖苷和糖苷配基在内的任何一种。组合物为浓缩形式，以易于消耗的剂量递送，例如丸剂，片剂，液体，胶囊或包括健康酒吧的食品补充剂。最常见的是，这些女性症状是潮热，骨质疏松症，睡眠障碍，绝经期症状，阴道干燥，经前期综合征或与性激素和月经有关的其他问题。

10. 发明授权

US06261565B1 Method of preparing and using isoflavones 有权
标题翻译：制备和使用异黄酮的方法
公开(公告)号：US06261565B1
公开(公告)日：2001-07-17
申请号：US09162038
申请日：1998-09-28
申请人： Mark Empie , Eric Gugger
发明人： Mark Empie , Eric Gugger
IPC分类号： A01N6500
CPC分类号： C07D311/36 , A23L33/105 , A23L33/11 , A23V2002/00 , A61K36/185 , A61K36/48 , A61K36/488 , A61K36/55 , A61K36/68 , A61K36/82 , A61K36/899 , Y10S514/823 , Y10S514/824 , Y10S514/874 , Y10S514/899 , Y10S514/923 , A61K2300/00 , A23V2250/2116 , A23V2250/2132
摘要： The invention provides for a refinement of phytochemicals in order to tailor the refined end product to particular human dietary needs. More particularly, a composition is prepared by extracting phytochemicals from plant matter. This composition is enriched preferably in two or more isoflavones, lignans, saponins, catechins and phenolic acids. Soy is the preferred source of these chemicals; however, other plants may also be used, such as red clover, kudzu, flax, and cocoa. The composition is a dietary supplement for treatment of various cancers, pre-and-post-menstrual syndromes, and various other disorders.
摘要翻译：本发明提供植物化学物质的改进，以便将精制的最终产物定制为特定的人类膳食需求。更具体地，通过从植物物质中提取植物化学物质来制备组合物。该组合物优选富含两种或更多种异黄酮，木脂素，皂角苷，儿茶素和酚酸。大豆是这些化学品的首选来源; 然而，也可以使用其他植物，例如红三叶草，葛根，亚麻和可可。该组合物是用于治疗各种癌症，前后经综合征和各种其他疾病的膳食补充剂。

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