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1. 发明授权

US6034081A Potentiation of biocide activity using an N-alkyl heterocyclic compound 失效
标题翻译：使用N-烷基杂环化合物增强杀生物活性
公开(公告)号：US6034081A
公开(公告)日：2000-03-07
申请号：US453001
申请日：1995-05-30
申请人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu
发明人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu
IPC分类号： A01N43/36 , A01N43/50 , A01N43/60 , A01N43/76 , A01N43/84 , C02F1/50 , A01N43/00 , A01N47/00
CPC分类号： A01N43/50 , A01N43/84 , C02F1/50 , C02F2103/023
摘要： A method for increasing the effectiveness of a microbicide is described, wherein a microbicide and an N-alkyl heterocyclic compound are applied to a substrate or aqueous system subject to the growth of microorganisms. The N-alkyl heterocyclic compound is applied in an amount effective to increase the microbicidal activity of the microbicide. The N-alkyl heterocyclic compound has the formula: ##STR1## The variable "In" ranges from 5 to 17, and the heterocyclic ring defined by ##STR2## is a substituted or unsubstituted ring having four to eight members. Microbicidal compositions are described where the microbicide and the N-alkyl heterocyclic compound are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates and in various aqueous systems are also described. The combination of the microbicide and the N-alkyl heterocyclic compound is particularly useful as a microbicide in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in industrial process waters.
摘要翻译：描述了一种增加杀微生物剂有效性的方法，其中将杀微生物剂和N-烷基杂环化合物施用于受微生物生长影响的底物或水性体系。以有效提高杀微生物剂的杀微生物活性的量施用N-烷基杂环化合物。 N-烷基杂环化合物具有下式：变量“In”为5至17，并且由所定义的杂环为具有4至8个成员的取代或未取代的环。描述了杀微生物组合物，其中杀微生物剂和N-烷基杂环化合物以有效控制至少一种微生物生长的组合量存在。还描述了控制各种底物和各种水性体系中微生物生长的方法。杀微生物剂和N-烷基杂环化合物的组合特别可用作皮革工业中的杀微生物剂，木材工业，造纸工业，纺织工业，农业和涂料工业以及工业过程水域

2. 再颁专利

USRE39148E1 Potentiation of the Microbicide 2-(Thiocyanomethylthio)benzothiazole using an n-alkyl heterocyclic compound 失效
标题翻译：使用正烷基杂环化合物对杀微生物剂2-（硫氰酸甲硫基）苯并噻唑的增强作用
公开(公告)号：USRE39148E1
公开(公告)日：2006-06-27
申请号：US10141080
申请日：2002-05-09
申请人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu
发明人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu
IPC分类号： C12Q1/02 , C12Q1/18 , A01N43/00
CPC分类号： A01N43/78 , A01N43/84 , A01N43/76 , A01N43/60 , A01N43/50 , A01N43/46 , A01N43/40 , A01N43/36 , A01N2300/00
摘要： Microbicidal compositions are described. The compositions comprise (a) 2-(Thiocyanomethylthio)benzothiazole (TCMTB) and (b) an N-alkyl heterocyclic compound of the formula: The variable “n” ranges from 5 to 17, and the heterocyclic ring defined by is a substituted or unsubstituted ring having four to eight members. Components (a) and (b) are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates or in aqueous systems are also described. Also described is the industrial application of the microbicidal composition in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in aqueous systems.
摘要翻译：描述了杀微生物剂组合物。组合物包含（a）2-（硫氰酸甲硫基）苯并噻唑（TCMTB）和（b）下式的N-烷基杂环化合物：变量“n”的范围为5至17，并且由下式定义的杂环是取代或未取代的环具有四至八个成员。组分（a）和（b）以有效控制至少一种微生物生长的组合量存在。还描述了控制微生物在各种底物或水性体系中生长的方法。还描述了杀皮组合物在皮革工业，木材工业，造纸工业，纺织工业，农业和涂料工业以及含水体系中的工业应用。

3. 再颁专利

USRE39033E1 Potentiation of the microbicide 2-(thiocyanomethylthio)benzothiazole using an N-alkyl heterocyclic compound 有权
标题翻译：使用N-烷基杂环化合物增强杀微生物剂2-（氰硫基甲硫基）苯并噻唑
公开(公告)号：USRE39033E1
公开(公告)日：2006-03-21
申请号：US10141079
申请日：2002-05-09
申请人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu , Dean T. Didato
发明人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu , Dean T. Didato
IPC分类号： A01N43/00 , A01N43/40 , A01N43/64 , A61K31/535
CPC分类号： A01N43/78 , A01N43/84 , A01N43/76 , A01N43/60 , A01N43/50 , A01N43/46 , A01N43/40 , A01N43/36 , A01N2300/00
摘要： Microbicidal compositions are described. The compositions comprise (a) 2-(Thiocyanomethylthio)benzothiazole (TCMTB) and (b) an N-alkyl heterocyclic compound of the formula: The variable “n” ranges from 5 to 17, and the heterocyclic ring defined by is a substituted or unsubstituted ring having four to eight members. Components (a) and (b) are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates or in aqueous systems are also described. Also described is the industrial application of the microbicidal composition in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in aqueous systems.
摘要翻译：描述了杀微生物剂组合物。组合物包含（a）2-（硫氰酸甲硫基）苯并噻唑（TCMTB）和（b）下式的N-烷基杂环化合物：变量“n”的范围为5至17，并且由下式定义的杂环是取代或未取代的环具有四至八个成员。组分（a）和（b）以有效控制至少一种微生物生长的组合量存在。还描述了控制微生物在各种底物或水性体系中生长的方法。还描述了杀皮组合物在皮革工业，木材工业，造纸工业，纺织工业，农业和涂料工业以及含水体系中的工业应用。

4. 发明授权

US6060466A Potentiation of the microbicide 2-(Thiocyanomethylthio)benzothiazole using an N-alkyl heterocyclic compound 失效
标题翻译：使用N-烷基杂环化合物对杀微生物剂2-（硫氰基甲硫基）苯并噻唑的增强作用
公开(公告)号：US6060466A
公开(公告)日：2000-05-09
申请号：US979182
申请日：1997-11-26
申请人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu , Dean T. Didato
发明人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu , Dean T. Didato
IPC分类号： A01N47/48 , A01N43/36 , A01N43/40 , A01N43/78 , A01N43/84 , A61K31/33 , C12Q1/02
CPC分类号： A01N43/78
摘要： Microbicidal compositions are described. The compositions comprise (a) 2-(Thiocyanomethylthio)benzothiazole (TCMTB) and (b) an N-alkyl heterocyclic compound of the formula: ##STR1## The variable "n" ranges from 5 to 17, and the heterocyclic ring defined by ##STR2## is a substituted or unsubstituted ring having four to eight members. Components (a) and (b) are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates or in aqueous systems are also described. Also described is the industrial application of the microbicidal composition in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in aqueous systems.
摘要翻译：描述了杀微生物剂组合物。组合物包含（a）2-（硫氰酸甲硫基）苯并噻唑（TCMTB）和（b）下式的N-烷基杂环化合物：变量“n”的范围为5至17，并且由下式定义的杂环是取代或未取代的环具有四至八个成员。组分（a）和（b）以有效控制至少一种微生物生长的组合量存在。还描述了控制微生物在各种底物或水性体系中生长的方法。还描述了杀皮组合物在皮革工业，木材工业，造纸工业，纺织工业，农业和涂料工业以及含水体系中的工业应用。

5. 发明授权

US5693631A Potentiation of the microbicide 2-(thiocyanomethylthio) benzothiazole using an N-alkyl heterocyclic compound 失效
标题翻译：使用N-烷基杂环化合物增强杀微生物剂2-（氰硫基甲硫基）苯并噻唑
公开(公告)号：US5693631A
公开(公告)日：1997-12-02
申请号：US456098
申请日：1995-05-30
申请人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu , Dean T. Didato
发明人： Marilyn S. Whittemore , Daniel E. Glover , S. Rao Rayudu , Dean T. Didato
IPC分类号： A01N47/48 , A01N43/36 , A01N43/40 , A01N43/78 , A01N43/84 , A01N43/00 , A01N43/64 , A61K31/535
CPC分类号： A01N43/78
摘要： Microbicidal compositions are described. The compositions comprise (a) 2-(Thiocyanomethylthio)benzothiazole (TCMTB) and (b) an N-alkyl heterocyclic compound of the formula: ##STR1## The variable "n" ranges from 5 to 17, and the heterocyclic ring defined by ##STR2## is a substituted or unsubstituted ring having four to eight members. Components (a) and (b) are present in a combined amount effective to control the growth of at least one microorganism. Methods for controlling the growth of microorganisms on various substrates or in aqueous systems are also described. Also described is the industrial application of the microbicidal composition in the leather industry, the lumber industry, the papermaking industry, the textile industry, the agricultural industry, and the coating industry, as well as in aqueous systems.
摘要翻译：描述了杀微生物剂组合物。组合物包含（a）2-（硫氰基甲硫基）苯并噻唑（TCMTB）和（b）下式的N-烷基杂环化合物：变量“n”的范围为5至17， IMAGE>是具有四至八个成员的取代或未取代的环。组分（a）和（b）以有效控制至少一种微生物生长的组合量存在。还描述了控制微生物在各种底物或水性体系中生长的方法。还描述了杀皮组合物在皮革工业，木材工业，造纸工业，纺织工业，农业和涂料工业以及含水体系中的工业应用。

6. 发明授权

US06211172B1 Methods and compositions for controlling biofouling using sulfonamides 失效
标题翻译：使用磺酰胺控制生物污损的方法和组合物
公开(公告)号：US06211172B1
公开(公告)日：2001-04-03
申请号：US09298821
申请日：1999-04-26
申请人： Mark L. Zollinger , Daniel E. Glover , Marilyn S. Whittemore , Stephen D. Bryant
发明人： Mark L. Zollinger , Daniel E. Glover , Marilyn S. Whittemore , Stephen D. Bryant
IPC分类号： A01N4340
CPC分类号： C09D5/14 , C02F1/50
摘要： The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one sulfonamide to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one sulfonamide to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The sulfonamide used in the method of the invention has the following formula: The present invention also relates to a composition containing the sulfonamides and useable in the above methods. The compositions comprise at least one sulfonamide in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
摘要翻译：本发明涉及一种抑制细菌粘附在潜水表面上的方法。该方法用有效量的至少一种磺酰胺接触潜表面以抑制细菌粘附到潜水表面。本发明还涉及一种用于控制水系统的生物污垢的方法。该方法添加有效量的至少一种磺酰胺以抑制细菌粘附到水系统内的浸没表面。该方法有效地控制生物污染，而不会基本上杀死污染的生物体。用于本发明方法的磺酰胺具有下式：本发明还涉及含有磺酰胺并可用于上述方法的组合物。组合物包含至少一种有效抑制细菌粘附到潜水或浸没表面的量的磺酰胺。

7. 发明授权

US6110452A Methods and compositions for controlling biofouling using polyglycol fatty acid esters 失效
标题翻译：使用聚二醇脂肪酸酯控制生物污损的方法和组合物
公开(公告)号：US6110452A
公开(公告)日：2000-08-29
申请号：US537085
申请日：1995-09-29
申请人： Daniel E. Glover , Marilyn S. Whittemore , Stephen D. Bryant
发明人： Daniel E. Glover , Marilyn S. Whittemore , Stephen D. Bryant
IPC分类号： C02F1/00 , A01N37/02 , A01N61/00 , C02F1/50 , C09D5/14 , C09D5/16
CPC分类号： C02F1/50 , A01N37/02 , A01N37/06 , C09D5/1625 , C02F2103/023
摘要： The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one polyglycol fatty acid ester to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one polyglycol fatty acid ester to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The present invention also relates to a composition containing polyglycol fatty acid esters and useable in the above methods. The compositions comprise at least one polyglycol fatty acid ester in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
摘要翻译：本发明涉及一种抑制细菌粘附在潜水表面上的方法。该方法用有效量的至少一种聚乙二醇脂肪酸酯接触潜浸表面以抑制细菌粘附到潜水表面。本发明还涉及一种用于控制水系统的生物污垢的方法。该方法添加有效量的至少一种聚乙二醇脂肪酸酯以抑制细菌粘附到水系统内的浸没表面。该方法有效地控制生物污染，而不会基本上杀死污染的生物体。本发明还涉及含有聚二醇脂肪酸酯的组合物，可用于上述方法。所述组合物包含至少一种聚乙二醇脂肪酸酯，其量有效地抑制细菌粘附到潜水或浸没的表面。

8. 发明授权

US5902808A Methods and compositions for controlling biofouling using N-alkyl heterocyclic compounds 失效
标题翻译：使用N-烷基杂环化合物控制生物污损的方法和组合物
公开(公告)号：US5902808A
公开(公告)日：1999-05-11
申请号：US536841
申请日：1995-09-29
申请人： Marilyn S. Whittemore , Daniel E. Glover , Joe C. Steelhammer , Stephen D. Bryant
发明人： Marilyn S. Whittemore , Daniel E. Glover , Joe C. Steelhammer , Stephen D. Bryant
IPC分类号： C02F1/00 , A01N43/40 , A01N43/84 , C02F1/50 , C09D5/14 , A61K31/535 , A01N43/00 , A01N43/36
CPC分类号： C02F1/50 , C09D5/14
摘要： The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one N-alkyl heterocyclic compound to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one N-alkyl heterocyclic compound to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The N-alkyl heterocyclic compound used in the method of the invention has the following formula: ##STR1## The substituent R.sup.1 is a C.sub.8 -C.sub.20 alkyl group. The heterocyclic ring is a 5-8 membered heterocyclic ring where X is O, NH, or CH.sub.2. R.sup.2 is methyl, hydroxymethyl, or hydroxyethyl. The integer n ranges from 0 to 3. The present invention also relates to a composition containing N-alkyl heterocyclic compounds and useable in the above methods. The compositions comprise at least one N-alkyl heterocyclic compound in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
摘要翻译：本发明涉及一种抑制细菌粘附在潜水表面上的方法。该方法用有效量的至少一种N-烷基杂环化合物接触潜表面以抑制细菌粘附到潜水表面。本发明还涉及一种用于控制水系统的生物污垢的方法。该方法添加有效量的至少一种N-烷基杂环化合物以抑制细菌粘附到水系统内的浸没表面。该方法有效地控制生物污染，而不会基本上杀死污染的生物体。用于本发明方法的N-烷基杂环化合物具有下式：取代基R 1为C 8 -C 20烷基。杂环是5-8元杂环，其中X是O，NH或CH2。 R2是甲基，羟甲基或羟乙基。整数n的范围为0-3。本发明还涉及含有N-烷基杂环化合物并可用于上述方法的组合物。组合物包含至少一种有效抑制细菌粘附到潜水或浸没表面的N-烷基杂环化合物。

9. 发明授权

US5814668A Methods and compositions for controlling biofouling using amides 失效
标题翻译：使用酰胺控制生物污损的方法和组合物
公开(公告)号：US5814668A
公开(公告)日：1998-09-29
申请号：US536978
申请日：1995-09-29
申请人： Marilyn S. Whittemore , Daniel E. Glover , Mark L. Zollinger , Stephen D. Bryant
发明人： Marilyn S. Whittemore , Daniel E. Glover , Mark L. Zollinger , Stephen D. Bryant
IPC分类号： C02F1/00 , A01N37/18 , A01N43/40 , A01N43/46 , A01N43/84 , C02F1/50 , C09D5/14
CPC分类号： A01N37/18 , C02F1/50
摘要： The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one amide to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one amide to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the bacteria. The amide used in the method of the invention has the following formula: ##STR1## The present invention also relates to compositions containing amides and useable in the above methods. The compositions comprise at least one amide in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
摘要翻译：本发明涉及一种抑制细菌粘附在潜水表面上的方法。该方法与有效量的至少一种酰胺接触该潜水表面以抑制细菌粘附到潜水表面。本发明还涉及一种用于控制水系统的生物污垢的方法。该方法添加有效量的至少一种酰胺以抑制细菌粘附到水系统内的浸没表面。该方法有效地控制生物污损，而不会基本上杀死细菌。用于本发明方法的酰胺具有下列结构式：含有酰胺的组合物并可用于上述方法。组合物包含至少一种有效抑制细菌粘附到潜水或浸没表面的酰胺。

10. 发明授权

US6030971A Methods and compositions for controlling biofouling using amides 有权
标题翻译：使用酰胺控制生物污损的方法和组合物
公开(公告)号：US6030971A
公开(公告)日：2000-02-29
申请号：US161756
申请日：1998-09-29
申请人： Marilyn S. Whittemore , Daniel E. Glover , Mark L. Zollinger , Stephen D. Bryant
发明人： Marilyn S. Whittemore , Daniel E. Glover , Mark L. Zollinger , Stephen D. Bryant
IPC分类号： C02F1/00 , A01N37/18 , A01N43/40 , A01N43/46 , A01N43/84 , C02F1/50 , C09D5/14 , A01N43/00 , A61K31/535
CPC分类号： A01N37/18 , C02F1/50
摘要： The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one amide to inhibit bacterial adhesion to the submergible surface. The present invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one amide to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the bacteria. The amide used in the method of the invention has the following formula: ##STR1## The present invention also relates to compositions containing amides and useable in the above methods. The compositions comprise at least one amide in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.
摘要翻译：本发明涉及一种抑制细菌粘附在潜水表面上的方法。该方法与有效量的至少一种酰胺接触该潜水表面以抑制细菌粘附到潜水表面。本发明还涉及一种用于控制水系统的生物污垢的方法。该方法添加有效量的至少一种酰胺以抑制细菌粘附到水系统内的浸没表面。该方法有效地控制生物污损，而不会基本上杀死细菌。在本发明方法中使用的酰胺具有下式：本发明还涉及含有酰胺的组合物并且可用于上述方法。组合物包含至少一种有效抑制细菌粘附到潜水或浸没表面的酰胺。

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