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    • 3. 发明授权
    • Cosmetic compositions
    • 化妆品组合物
    • US4711775A
    • 1987-12-08
    • US677891
    • 1984-12-04
    • Walter DittmarEberhard FuttererGerhard Lohaus
    • Walter DittmarEberhard FuttererGerhard Lohaus
    • A61K8/00A61K20060101A61K8/33A61K8/37A61K8/49A61K8/92A61K31/12A61K31/44A61P17/08A61Q5/00A61Q5/02A61Q5/12A61Q7/00C07D20060101C07D207/26C07D213/89C11D3/28C11D3/48A61K7/06
    • A61Q5/006A61K8/4926Y10S424/01Y10S424/02Y10S424/04
    • A cosmetic composition comprising a content of an 1-hydroxy-2-pyridone of the general formula ##STR1## in which R.sub.1 stands for hydrogen, alkyl of 1 to 17 carbon atoms, alkenyl of 2 to 17 carbon atoms, cycloalkyl of 5 to 8 carbon atoms, bicycloalkyl of 7 to 9 carbon atoms, cycloalkyl-alkyl of 1 to 4 alkyl carbon atoms, the cycloalkyl groups being optionally substituted by alkyl groups of 1 to 4 carbon atoms, aryl, aralkyl of 1 to 4 alkyl carbon atoms, aryl-alkenyl of 2 to 4 alkenyl carbon atoms, aryloxy-alkyl or arylthio-alkyl of 1 to 4 alkyl carbon atoms, benzhydryl, phenylsulfonyl-alkyl of 1 to 4 alkyl carbon atoms, furyl or furyl-alkenyl of 2 to 4 alkenyl carbon atoms, the aryl groups being optionally substituted by alkyl of 1 to 4 carbon atoms, by alkoxy of 1 to 4 carbon atoms, by nitro, cyano or halogen atoms,R.sub.2 stands for hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl or alkinyl of 2 to 4 carbon atoms, halogen atoms or benzyl,R.sub.3 stands for hydrogen, alkyl of 1 to 4 carbon atoms or phenyl, andR.sub.4 stands for hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms, methoxy-methyl, halogen or benzyl, and/or salt thereof, which may be used as an anti-dandruff agent.
    • 一种化妆品组合物,其包含通式“IMAGE”的1-羟基-2-吡啶酮的含量,其中R1代表氢,1至17个碳原子的烷基,2至17个碳原子的链烯基,5至8个的环烷基 碳原子数为7〜9的双环烷基,1〜4个碳原子的环烷基 - 烷基,环烷基任选被1〜4个碳原子的烷基取代,芳基,1〜4个碳原子的芳烷基,芳基 2至4个烯基碳原子的烯基,1至4个烷基碳原子的芳氧基 - 烷基或芳硫基 - 烷基,2至4个烷基碳原子的二苯甲基,苯基磺酰基 - 烷基,2至4个烯基碳原子的呋喃基或呋喃基 - 烯基 ,芳基任选被1至4个碳原子的烷基,1至4个碳原子的烷氧基,硝基,氰基或卤素原子取代,R2代表氢,1至4个碳原子的烷基,烯基或炔基 2至4个碳原子,卤素原子或苄基,R3代表氢,1至4个碳原子的烷基 R苯基,R4代表氢,1至4个碳原子的烷基,2至4个碳原子的链烯基,甲氧基 - 甲基,卤素或苄基,和/或其盐,可用作抗头皮屑剂。
    • 4. 发明授权
    • Pyridones as antidandruff agents
    • 吡啶酮作为去头皮屑剂
    • US4185106A
    • 1980-01-22
    • US605210
    • 1975-08-15
    • Walter DittmarEberhard FuttererGerhard Lohaus
    • Walter DittmarEberhard FuttererGerhard Lohaus
    • A61K8/49A61K31/44A61Q5/00
    • A61Q5/006A61K8/4926Y10S424/04
    • A cosmetic composition comprising a content of an 1-hydroxy-2-pyridone of the general formula ##STR1## in which R.sub.1 stands for hydrogen, alkyl of 1 to 17 carbon atoms, alkenyl of 2 to 17 carbon atoms, cycloalkyl of 5 to 8 carbon atoms, bicycloalkyl of 7 to 9 carbon atoms, cycloalkyl-alkyl of 1 to 4 alkyl carbon atoms, the cycloalkyl groups being optionally substituted by alkyl groups of 1 to 4 carbon atoms, aryl, aralkyl of 1 to 4 alkyl carbon atoms, aryl-alkenyl of 2 to 4 alkenyl carbon atoms, aryloxy-alkyl or arylthio-alkyl of 1 to 4 alkyl carbon atoms, benzhydryl, phenylsulfonyl-alkyl of 1 to 4 alkyl carbon atoms, furyl or furyl-alkenyl of 2 to 4 alkenyl carbon atoms, the aryl groups being optionally substituted by alkyl of 1 to 4 carbon atoms, by alkoxy of 1 to 4 carbon atoms, by nitro, cyano or halogen atoms, R.sub.2 stands for hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl or alkinyl of 2 to 4 carbon atoms, halogen atoms or benzyl, R.sub.3 stands for hydrogen, alkyl of 1 to 4 carbon atoms or phenyl, and R.sub.4 stands for hydrogen, alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 4 carbon atoms, methoxy-methyl, halogen or benzyl, and/or salt thereof, which may be used as an anti-dandruff agent.
    • 一种化妆品组合物,其包含通式“IMAGE”的1-羟基-2-吡啶酮的含量,其中R1代表氢,1至17个碳原子的烷基,2至17个碳原子的链烯基,5至8个的环烷基 碳原子数为7〜9的双环烷基,1〜4个碳原子的环烷基 - 烷基,环烷基任选被1〜4个碳原子的烷基取代,芳基,1〜4个碳原子的芳烷基,芳基 2至4个烯基碳原子的烯基,1至4个烷基碳原子的芳氧基 - 烷基或芳硫基 - 烷基,2至4个烷基碳原子的二苯甲基,苯基磺酰基 - 烷基,2至4个烯基碳原子的呋喃基或呋喃基 - 烯基 ,芳基任选被1至4个碳原子的烷基,1至4个碳原子的烷氧基,硝基,氰基或卤素原子取代,R2代表氢,1至4个碳原子的烷基,烯基或炔基 2至4个碳原子,卤素原子或苄基,R3代表氢,1至4个碳原子的烷基 R苯基,R4代表氢,1至4个碳原子的烷基,2至4个碳原子的链烯基,甲氧基 - 甲基,卤素或苄基,和/或其盐,可用作抗头皮屑剂。