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1. 发明申请

US20050197319A1 Allergen inactivating agent 有权
标题翻译：过敏原灭活剂
公开(公告)号：US20050197319A1
公开(公告)日：2005-09-08
申请号：US11045328
申请日：2005-01-31
申请人： Mami Nonomura , Kimihiko Hori , Hiroshi Nojiri , Hiroyuki Yanagida , Fumiko Okuda
发明人： Mami Nonomura , Kimihiko Hori , Hiroshi Nojiri , Hiroyuki Yanagida , Fumiko Okuda
IPC分类号： A61K8/02 , A61K8/04 , A61K8/73 , A61K31/715 , A61K47/10 , A61K47/18 , A61K47/24 , A61Q17/00 , A61Q19/00 , A62B18/00 , A61K31/717 , A61K31/716
CPC分类号： A61Q17/00 , A61K8/0208 , A61K8/0212 , A61K8/0229 , A61K8/046 , A61K8/731 , A61K9/0014 , A61K31/715 , A61K47/10 , A61K47/18 , A61K47/183 , A61K47/24 , A61Q19/00 , A62B18/00
摘要： An allergen inactivating agent is provided which has no adverse effects on the human body and which does not cause problems such as color development. An allergen inactivating agent containing a polysaccharide derivative as its effective component, wherein said polysaccharide derivative has a cellulose ether or a starch ether as its backbone, and some or all of hydrogen atoms in the hydroxy group of the polysaccharide derivative are substituted by a group represented by the following general formula (1): -E1-(OA)n-E2-R (1) wherein E1 represents an alkylene containing 1 to 6 carbon atoms optionally substituted with hydroxy group or oxo group; n represents a number of 0 to 50; A independently represents an alkylene containing 1 to 6 carbon atoms, the number of A being n; E2 represents ether bond or oxycarbonyl group; R represents an alkyl group containing 4 to 30 carbon atoms optionally substituted with hydroxy group, a sulfoalkyl group containing 1 to 5 carbon atoms optionally substituted with hydroxy group, or a salt thereof.
摘要翻译：提供了对人体没有不良影响并且不会引起颜色发展等问题的过敏原灭活剂。一种含有多糖衍生物作为其有效成分的变应原灭活剂，其中所述多糖衍生物具有纤维素醚或淀粉醚作为其主链，并且多糖衍生物的羟基中的部分或全部氢原子被代表的基团取代通过以下通式（1）：<？in-line-formula description =“In-line Formulas”end =“lead”？> - E ^{- （OA） R（1）<？in-line-formula description =“In-line Formulas”end =“tail”？>其中E <1> 表示任选被羟基或氧代基取代的含有1至6个碳原子的亚烷基; n表示0〜50的数; A独立地表示含有1至6个碳原子的亚烷基，A的数目为n; E 2表示醚键或氧羰基; R表示任选被羟基取代的含有4〜30个碳原子的烷基，可以被羟基取代的含有1〜5个碳原子的磺基烷基或其盐。}

2. 发明授权

US08133991B2 Allergen inactivating agent 有权
标题翻译：过敏原灭活剂
公开(公告)号：US08133991B2
公开(公告)日：2012-03-13
申请号：US11045328
申请日：2005-01-31
申请人： Mami Nonomura , Kimihiko Hori , Hiroshi Nojiri , Hiroyuki Yanagida , Fumiko Okuda
发明人： Mami Nonomura , Kimihiko Hori , Hiroshi Nojiri , Hiroyuki Yanagida , Fumiko Okuda
IPC分类号： C07H1/00 , C08B31/08 , C08B11/08 , A61K31/715
CPC分类号： A61Q17/00 , A61K8/0208 , A61K8/0212 , A61K8/0229 , A61K8/046 , A61K8/731 , A61K9/0014 , A61K31/715 , A61K47/10 , A61K47/18 , A61K47/183 , A61K47/24 , A61Q19/00 , A62B18/00
摘要： An allergen inactivating agent is provided which has no adverse effects on the human body and which does not cause problems such as color development.An allergen inactivating agent containing a polysaccharide derivative as its effective component, wherein said polysaccharide derivative has a cellulose ether or a starch ether as its backbone, and some or all of hydrogen atoms in the hydroxy group of the polysaccharide derivative are substituted by a group represented by the following general formula (1): -E1-(OA)n-E2-R (1) wherein E1 represents an alkylene containing 1 to 6 carbon atoms optionally substituted with hydroxy group or oxo group; n represents a number of 0 to 50; A independently represents an alkylene containing 1 to 6 carbon atoms, the number of A being n; E2 represents ether bond or oxycarbonyl group; R represents an alkyl group containing 4 to 30 carbon atoms optionally substituted with hydroxy group, a sulfoalkyl group containing 1 to 5 carbon atoms optionally substituted with hydroxy group, or a salt thereof.
摘要翻译：提供了对人体没有不良影响并且不会引起颜色发展等问题的过敏原灭活剂。一种含有多糖衍生物作为其有效成分的变应原灭活剂，其中所述多糖衍生物具有纤维素醚或淀粉醚作为其主链，多糖衍生物的羟基中的部分或全部氢原子被代表的基团取代通式（1）表示：-E1-（OA）n-E2-R（1）其中E1表示任选被羟基或氧代基取代的含有1至6个碳原子的亚烷基; n表示0〜50的数; A独立地表示含有1至6个碳原子的亚烷基，A的数目为n; E2表示醚键或氧羰基; R表示任选被羟基取代的含有4〜30个碳原子的烷基，可以被羟基取代的含有1〜5个碳原子的磺基烷基或其盐。

3. 发明申请

US20050256082A1 Allergen inactivator 审中-公开
标题翻译：过敏原灭活剂
公开(公告)号：US20050256082A1
公开(公告)日：2005-11-17
申请号：US10519474
申请日：2003-07-02
申请人： Mami Nonomura , Kimihiko Hori , Hiroshi Nojiri
发明人： Mami Nonomura , Kimihiko Hori , Hiroshi Nojiri
IPC分类号： A61K8/02 , A61K8/04 , A61K8/73 , A61K31/715 , A61K47/10 , A61K47/18 , A61K47/24 , A61P37/08 , A61Q17/00 , A61Q19/00 , A62B18/00 , A61K31/717 , A61K31/716
CPC分类号： A61K8/732 , A61K8/0229 , A61K8/731 , A61K9/0014 , A61K31/715 , A61K47/10 , A61K47/18 , A61K47/183 , A61K47/24 , A61Q19/00 , A62B18/00 , C08L1/26 , C08L1/284 , C08L1/32 , C08L3/08
摘要： This invention relates to an allergen inactivating agent containing a polysaccharide derivative as its effective component, wherein said polysaccharide derivative has a cellulose ether or a starch ether as its backbone, and some or all of hydrogen atoms in the hydroxy group of the polysaccharide derivative are substituted by a group represented by the following general formula (1): -E1-(OA)n-E2-R (1) wherein E1 represents an alkylene containing 1 to 6 carbon atoms optionally substituted with hydroxy group or oxo group; n represents a number of 0 to 50; A independently represents an alkylene containing 1 to 6 carbon atoms, the number of A being n; E2 represents ether bond or oxycarbonyl group; R represents an alkyl group containing 4 to 30 carbon atoms optionally substituted with hydroxy group, a sulfoalkyl group containing 1 to 5 carbon atoms optionally substituted with hydroxy group, or a salt thereof. By using such allergen inactivating agent, house dust and other environmental allergens can be inactivated with no adverse effects on the human body and without causing problems such as color development.
摘要翻译：本发明涉及含有多糖衍生物作为其有效成分的变应原灭活剂，其中所述多糖衍生物具有纤维素醚或淀粉醚作为其主链，多糖衍生物的羟基中的一部分或全部氢原子被取代由以下通式（1）表示的基团：<？in-line-formula description =“In-line Formulas”end =“lead”？> - E <1> - （OA）（1）<？in-line-formula description =“In-line Formulas”end =“tail”？>其中E 1 代表任选被羟基或氧代基取代的含有1至6个碳原子的亚烷基; n表示0〜50的数; A独立地表示含有1至6个碳原子的亚烷基，A的数目为n; E 2表示醚键或氧羰基; R表示任选被羟基取代的含有4〜30个碳原子的烷基，可以被羟基取代的含有1〜5个碳原子的磺基烷基或其盐。通过使用这种过敏原灭活剂，可以灭活房屋尘埃和其他环境过敏原，对人体没有不利影响，并且不会引起颜色发展等问题。

4. 发明授权

US6123934A Hair cosmetic composition 失效
标题翻译：头发化妆品组成
公开(公告)号：US6123934A
公开(公告)日：2000-09-26
申请号：US879812
申请日：1997-06-20
申请人： Takashi Koyama , Kazuyo Watanabe , Hiroshi Nojiri , Sachio Naito , Michitaka Sawada , Genji Imokawa , Hidehisa Takahashi , Toshiki Kobayashi
发明人： Takashi Koyama , Kazuyo Watanabe , Hiroshi Nojiri , Sachio Naito , Michitaka Sawada , Genji Imokawa , Hidehisa Takahashi , Toshiki Kobayashi
IPC分类号： A61K8/64 , A61K8/73 , A61K8/85 , A61K8/86 , A61K8/891 , A61K8/895 , A61K8/898 , A61Q5/00 , A61Q5/02 , A61K7/07 , A61K7/00
CPC分类号： A61K8/898 , A61K8/64 , A61K8/731 , A61K8/85 , A61K8/86 , A61K8/891 , A61Q5/00 , A61Q5/02 , A61K2800/594 , A61K2800/70
摘要： The present invention provides a hair cosmetic composition containing an antibody (a) to hair or a hair extract obtained from egg yolk of poultry immunized with the hair or hair extract, and a polymer emulsion (b). The hair cosmetic composition of the invention can provide excellent properties including softness, moistened feel, and smoothness. In addition, since it is adsorbed only onto a specified part of the hair, stickiness or greasiness of the hair can be prevented. The composition also prevents occurrence of split hairs, and even repair the split hairs. These effects are not lost by repeated ordinary shampooings.
摘要翻译：本发明提供一种含有头发的抗体（a）和由毛发或毛发提取物免疫的家禽的蛋黄获得的毛发提取物和聚合物乳液（b）的毛发化妆品组合物。本发明的毛发化妆品组合物可以提供优异的性质，包括柔软度，润湿感和平滑度。此外，由于仅吸附在毛发的特定部位上，因此可以防止头发的粘性或油性。该组合物还防止分裂毛发生，甚至修复分裂毛发。这些效果不会被重复的普通洗发水所损失。

5. 发明授权

US5763583A Process for producing solubilized protein 失效
标题翻译：生产溶解蛋白的方法
公开(公告)号：US5763583A
公开(公告)日：1998-06-09
申请号：US540318
申请日：1995-10-06
申请人： Kozo Arai , Hiroshi Nojiri , Sachio Naito
发明人： Kozo Arai , Hiroshi Nojiri , Sachio Naito
IPC分类号： C07K1/107 , C07K1/113 , C07K14/47 , A61K38/17
CPC分类号： C07K1/1136 , C07K1/1077 , C07K1/1133 , C07K14/4741
摘要： A process for the production of a solubilized protein is disclosed, which is obtained by reducing disulfide bonds in a disulfide bond-containing water-insoluble protein material into mercapto groups and subsequently converting a part or an entire portion thereof into carboxymethyldisulfide groups. In particular, the disclosed process for the production of a solubilized protein which comprises (a) treating a disulfide bond-containing water-insoluble protein material with an aqueous alkaline solution of a reducing agent, and (b) reacting the protein treated by step (a) with thioglycolic acid in the presence of an oxidizing agent under a weakly acidic to a weakly alkaline condition. A process for the production of regenerated protein products, which comprises regenerating disulfide bonds in the solubilized protein, is also disclosed.
摘要翻译：公开了生产溶解蛋白质的方法，其通过将含二硫键的水不溶性蛋白质材料中的二硫键还原成巯基并随后将其部分或全部转化成羧甲基二硫化物基团获得。特别地，本发明公开的生产溶解蛋白的方法包括：（a）用还原剂的碱性水溶液处理含二硫键的水不溶性蛋白质材料，和（b）使由步骤 a）在弱酸性至弱碱性条件下在氧化剂存在下用巯基乙酸进行。还公开了生产再生蛋白质产物的方法，其包括在溶解的蛋白质中再生二硫键。

6. 发明申请

US20110200694A1 Promotors of Ceramide's Generation 审中-公开
标题翻译：神经酰胺一代的启动子
公开(公告)号：US20110200694A1
公开(公告)日：2011-08-18
申请号：US13059329
申请日：2009-08-17
申请人： Wan Zhang Qin , Chun Xin Yang , Fan Qi Kong , Hiroshi Nojiri , Shotaro Ito
发明人： Wan Zhang Qin , Chun Xin Yang , Fan Qi Kong , Hiroshi Nojiri , Shotaro Ito
IPC分类号： A61K36/484 , A61K36/232 , A61K36/64 , A61K36/284 , A61K36/898 , A61K36/704 , A61K36/346 , A61K36/53 , A61K36/8945 , A61P17/00 , A61P35/00 , A61P29/00 , A61P19/00
CPC分类号： A61K36/898 , A61K8/97 , A61K36/232 , A61K36/284 , A61K36/346 , A61K36/484 , A61K36/533 , A61K36/64 , A61K36/70 , A61K36/708 , A61K36/8945 , A61Q19/00
摘要： The present invention provides a pharmaceutical composition or a cosmetic product which can accelerate production of ceramide in cells. The ceramide production-accelerating agent contains a plant selected from the group consisting of Radix Heraclei Scabridi, Rhizoma Dioscoreae, Radix Rehmanniae, Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Pseudobulbus Bletillae, Radix Polygoni Multiflori, Radix Platycodi, and Herba Leonuli, or an extract thereof as an active ingredient. Further, the present invention provides a moisturizing agent containing a plant selected from the group consisting of Herba Leonuri and Rhizoma Dioscoreae, or an extract thereof as an active ingredient.
摘要翻译：本发明提供可以加速细胞中神经酰胺生产的药物组合物或化妆品。神经酰胺生产促进剂含有选自以下的植物：山茱萸，山茱萸，地黄，大黄，甘草，赤芍，白芍，白芍，，或其提取物作为活性成分。此外，本发明提供一种含有选自以下的植物的保湿剂，其中，所述植物选自草本植物（Rhizoma Dioscoreae）或其提取物作为活性成分。

7. 发明申请

US20080057841A1 Sander 有权
标题翻译：桑德尔
公开(公告)号：US20080057841A1
公开(公告)日：2008-03-06
申请号：US11896052
申请日：2007-08-29
申请人： Hirokazu Hagiwara , Hiroshi Nojiri
发明人： Hirokazu Hagiwara , Hiroshi Nojiri
IPC分类号： B24B7/10
CPC分类号： B24B55/055 , B24B23/04
摘要： A motor is disposed in a main body and has a rotary shaft. A base is disposed below the main body. The base is coupled to the rotary shaft and adapted to make eccentric motions in accordance with rotations of the rotary shaft. A first receptacle is disposed in the main body. A second receptacle is disposed in the base. A foot is disposed between the first receptacle and the second receptacle. The foot includes a foot body made of metal, and elastic members provided on both ends of the foot body and respectively fitted into the first receptacle and the second receptacle, so that the foot body is pivotably supported between the first receptacle and the second receptacle. An elastic sleeve is fitted onto a part of an outer periphery of the foot body while being compressed by the first receptacle and the second receptacle.
摘要翻译：电动机设置在主体中并具有旋转轴。基座设置在主体下方。基座与旋转轴连接，适于根据旋转轴的转动进行偏心运动。第一容器设置在主体中。第二容器设置在基座中。脚部设置在第一容器和第二容器之间。脚包括由金属制成的脚本体，以及弹性构件，其设置在脚本体的两端并分别装配到第一容器和第二容器中，使得脚体可枢转地支撑在第一容器和第二容器之间。当被第一容器和第二容器压缩时，弹性套筒装配到脚本体的外周的一部分上。

8. 发明授权

US5976519A Yolk antibody-containing hair care product 失效
标题翻译：含有蛋黄抗体的护发产品
公开(公告)号：US5976519A
公开(公告)日：1999-11-02
申请号：US974510
申请日：1992-11-12
申请人： Hiroshi Nojiri , Sachio Naito , Hidehisa Takahashi , Masaru Fujiki , Mujo Kim
发明人： Hiroshi Nojiri , Sachio Naito , Hidehisa Takahashi , Masaru Fujiki , Mujo Kim
IPC分类号： A61K8/00 , A61K8/64 , A61K8/98 , A61K39/395 , A61Q5/00 , A61Q5/02 , A61Q5/12 , A61Q7/00 , C07K16/00 , A61K7/06
CPC分类号： A61Q5/00 , A61K8/64 , A61K8/982 , A61Q7/00 , C07K16/00 , Y10S514/88
摘要： A hair care product contains a yolk antibody (a yolk-derived, anti-hair antibody) which has been obtained from an egg of a domestic fowl immunized using, as an antigen, whole human hair, e.g., normal human hair or human hair damaged by permanent waving, dyeing or bleaching, hair particles obtained by grinding constituent tissues of human hair, the keratin protein extracted from the human hair, or a hydrolysate of the keratin protein.
摘要翻译：毛发护理产品含有从使用免疫的家禽的鸡蛋获得的蛋黄抗体（蛋黄衍生的抗毛发抗体）作为抗原，整个人的头发，例如正常人的头发或人的头发被损坏通过永久挥发，染色或漂白，通过研磨人毛组织组织获得的毛发颗粒，从人发提取的角蛋白蛋白质或角蛋白蛋白质的水解产物。

9. 发明授权

US07819725B2 Sander 有权
标题翻译：桑德尔
公开(公告)号：US07819725B2
公开(公告)日：2010-10-26
申请号：US11896052
申请日：2007-08-29
申请人： Hirokazu Hagiwara , Hiroshi Nojiri
发明人： Hirokazu Hagiwara , Hiroshi Nojiri
IPC分类号： B24B23/00
CPC分类号： B24B55/055 , B24B23/04
摘要： A motor is disposed in a main body and has a rotary shaft. A base is disposed below the main body. The base is coupled to the rotary shaft and adapted to make eccentric motions in accordance with rotations of the rotary shaft. A first receptacle is disposed in the main body. A second receptacle is disposed in the base. A foot is disposed between the first receptacle and the second receptacle. The foot includes a foot body made of metal, and elastic members provided on both ends of the foot body and respectively fitted into the first receptacle and the second receptacle, so that the foot body is pivotably supported between the first receptacle and the second receptacle. An elastic sleeve is fitted onto a part of an outer periphery of the foot body while being compressed by the first receptacle and the second receptacle.
摘要翻译：电动机设置在主体中并具有旋转轴。基座设置在主体下方。基座与旋转轴连接，适于根据旋转轴的转动进行偏心运动。第一容器设置在主体中。第二容器设置在基座中。脚部设置在第一容器和第二容器之间。脚包括由金属制成的脚本体，以及弹性构件，其设置在脚本体的两端并分别装配到第一容器和第二容器中，使得脚体可枢转地支撑在第一容器和第二容器之间。当被第一容器和第二容器压缩时，弹性套筒装配到脚本体的外周的一部分上。

10. 外观设计

USD585258S1 Portable electric sander 有权
标题翻译：便携式电动砂光机
公开(公告)号：USD585258S1
公开(公告)日：2009-01-27
申请号：US29322100
申请日：2008-07-29
申请人： Hiroshi Nojiri , Yuji Yamamoto
设计人： Hiroshi Nojiri , Yuji Yamamoto

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