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1. 发明申请

US20090092583A1 BRAIN-LOCALIZING CELLS AND USES THEREOF 审中-公开
标题翻译：脑局部化细胞及其用途
公开(公告)号：US20090092583A1
公开(公告)日：2009-04-09
申请号：US12064691
申请日：2006-08-25
申请人： Makoto Sawada , Hiroyuki Mukaiyama
发明人： Makoto Sawada , Hiroyuki Mukaiyama
IPC分类号： A61K35/66 , C12N1/19
CPC分类号： C07K7/06 , A61K47/6901
摘要： It was discovered that cells expressing brain-localizing polypeptides on the cell surface can pass through the blood-brain barrier and therefore have the activity of translocating to the brain. By introducing desired substances into such brain-localizing cells, the substances can also be translocated to the brain. For example, by intravenously administering brain-localizing cells into which pharmaceutical agents having therapeutic effects on brain diseases have been introduced, such agents can be efficiently delivered into the brain and the brain diseases can be effectively treated.
摘要翻译：已经发现，在细胞表面上表达脑定位多肽的细胞可以通过血脑屏障，因此具有易位于脑的活性。通过将所需物质引入这种脑定位细胞中，该物质也可以被转移到脑中。例如，通过静脉内施用已经引入了对脑疾病具有治疗作用的药剂的脑定位细胞，可以有效地将这些药物输送到脑中，并且可以有效地治疗脑部疾病。

2. 发明授权

US08693289B2 Timepiece device with multiple-hand 有权
标题翻译：钟表装置多手
公开(公告)号：US08693289B2
公开(公告)日：2014-04-08
申请号：US13164841
申请日：2011-06-21
申请人： Makoto Sawada
发明人： Makoto Sawada
IPC分类号： G04C9/00
CPC分类号： G04C3/146
摘要： A timepiece device with multiple-hand includes: one or more hands driven to rotate by one or more driving motors; one or more gear train mechanisms include gears which transmit a rotation movement of the driving motors to the hands; and a support plate which supports the gears; wherein the gears include: a first gear which includes a pair of gear members provided on front and rear sides of the support plate; a second gear which meshes with a gear member provided on the rear side to transmit a rotation movement of one of the driving motors to the first gear; and a third gear which meshes with a gear member provided on the front side to transmit a rotation movement of one of the driving motors to the hands.
摘要翻译：具有多手的钟表装置包括：一个或多个手由一个或多个驱动马达驱动旋转; 一个或多个齿轮系机构包括将驱动马达的旋转运动传递到手的齿轮; 以及支撑齿轮的支撑板; 其中所述齿轮包括：第一齿轮，其包括设置在所述支撑板的前侧和后侧的一对齿轮构件; 第二齿轮与设置在后侧的齿轮构件啮合，以将一个驱动马达的旋转运动传递到第一齿轮; 以及与设置在前侧的齿轮构件啮合的第三齿轮，以将驱动马达中的一个的旋转运动传递给手。

3. 发明申请

US20090043468A1 CONTROLLING SYSTEM FOR VEHICLE WITH CONTINUOUSLY VARIABLE TRANSMISSION 有权
标题翻译：具有连续可变传动的车辆控制系统
公开(公告)号：US20090043468A1
公开(公告)日：2009-02-12
申请号：US12036798
申请日：2008-02-25
申请人： Hiroki KONDO , Tadashi Tamura , Akira Hino , Makoto Sawada , Hiroji Taniguchi
发明人： Hiroki KONDO , Tadashi Tamura , Akira Hino , Makoto Sawada , Hiroji Taniguchi
IPC分类号： B60W10/10 , G06F17/00
CPC分类号： F02D41/10 , B60W10/06 , B60W10/107 , B60W30/18009 , B60W30/18027 , B60W40/068 , B60W2520/105 , B60W2710/0666 , B60W2710/1011 , B60W2710/105 , F02D29/00 , F02D2250/18 , F16H61/66259 , F16H2061/6611 , F16H2302/00 , Y10T477/619
摘要： A controlling system for a vehicle with a continuously variable transmission, which can render a sufficient accelerating feeling in responsive to a driver's requirement. A controller, upon judgment of an acceleration requirement, sets a target drive force higher than the target drive force upon normal calculation upon normal operation of an accelerator pedal, and sets a target rotation speed for acceleration higher than the target rotation speed upon the normal operation and increasing with an increase of the vehicle speed by a predetermined gradient. The speed change ratio of the continuously variable transmission and the output torque of the engine are controlled such that the set target drive force is achieved, and an input shaft rotation speed of the continuously variable transmission coincides with the target rotation speed for the set acceleration. Thus, upon acceleration requirement by the driver, the target drive force increases and the output rotation speed of the drive source increases so that the sufficiently high accelerating feeling from the vehicle can be obtained.
摘要翻译：一种用于具有无级变速器的车辆的控制系统，其可以响应于驾驶员的要求而产生足够的加速感。控制器在加速要求判定时，在通常的加速踏板动作时，在通常运算时，将目标驱动力设定为比目标驱动力高的目标驱动力，并且在通常运转时将加速度的目标转速设定为高于目标转速并且随着车速的增加而增加预定的梯度。控制无级变速器的变速比和发动机的输出转矩，使得实现设定目标驱动力，并且无级变速器的输入轴转速与设定加速度的目标转速一致。因此，在驾驶员的加速要求下，目标驱动力增加，驱动源的输出转速增加，从而可以获得来自车辆的足够高的加速感。

4. 发明授权

US07333063B2 Electronic device and antenna apparatus 有权
标题翻译：电子设备和天线装置
公开(公告)号：US07333063B2
公开(公告)日：2008-02-19
申请号：US11516918
申请日：2006-09-07
申请人： Junro Yano , Soh Kimura , Makoto Sawada
发明人： Junro Yano , Soh Kimura , Makoto Sawada
IPC分类号： H01Q1/22 , H01Q7/00 , G04B47/00
CPC分类号： H01Q7/08 , G04G21/04 , G04R60/12 , H01Q1/273
摘要： In an electronic device having a metal device case, and an antenna disposed inside the device case, a magnetic member having a magnetic permeability higher than a magnetic permeability of the device case is placed between an inner surface of the device case and the antenna.
摘要翻译：在具有金属器件壳体的电子设备和设置在器件壳体内部的天线中，具有比器件壳体的磁导率高的磁导率的磁性部件被放置在器件壳体的内表面和天线之间。

5. 发明申请

US20060233769A1 Established cell line of microglia 审中-公开
标题翻译：建立小胶质细胞系
公开(公告)号：US20060233769A1
公开(公告)日：2006-10-19
申请号：US11445564
申请日：2006-06-02
申请人： Makoto Sawada
发明人： Makoto Sawada
IPC分类号： A61K35/30 , C12Q1/68 , C12N5/08
CPC分类号： A61K48/00 , A61K38/00 , C12N5/0622 , C12N2501/22 , C12N2510/00
摘要： A subcultivatable, established microglia having the following properties. (a) Form: Both or either of a macrophage-like or spherical form in the presence of a granulocyte-macrophage colony stimulation factor and a branched form similar to branched microglia present in the brain in the absence of the factor. (b) Functional characteristics: specific affinity for the brain highly poor phagocytic action. (c) Cell proliferation: proliferative depending upon a granulocyte-macrophage colony stimulation factor. Preparation, separation, and screening methods of the microglia, a pharmaceutical composition using the microglia, and a method for treatment of cerebral diseases using the composition.
摘要翻译：具有以下性质的可转移性良好的小胶质细胞。（a）形式：在存在粒细胞 - 巨噬细胞集落刺激因子的情况下是巨噬细胞样或球形的两种或任何一种，并且在不存在该因子的情况下，存在于脑中存在的支链小胶质细胞。（b）功能特征：对脑的特异性亲和力差的吞噬作用。（c）细胞增殖：取决于粒细胞 - 巨噬细胞集落刺激因子的增殖。小胶质细胞的制备，分离和筛选方法，使用小胶质细胞的药物组合物，以及使用该组合物治疗脑疾病的方法。

6. 发明授权

US06217469B1 Control system for continuously variable transmission 失效
标题翻译：无级变速器控制系统
公开(公告)号：US06217469B1
公开(公告)日：2001-04-17
申请号：US09116543
申请日：1998-07-16
申请人： Makoto Sawada , Hirofumi Okahara
发明人： Makoto Sawada , Hirofumi Okahara
IPC分类号： F16H1106
CPC分类号： F16H61/66272 , F16H2059/467 , F16H2061/66281 , Y10T477/327 , Y10T477/34 , Y10T477/624 , Y10T477/62429
摘要： A control system controls a line pressure applied to a CVT upon taking account of a certrifugal pressure caused by a rotation of pulleys. The control system determines whether the centrifugal pressure is greater than a predeterminied value only by which the pulley transmits an input torque from an engine. When the determination is affirmative, a lower limit of a duty ratio for operating a line pressure control valve is switched from a lower limit of a linear range to 0% duty ratio. Therefore, an actual transmissiou ratio control range is expanded while preventing an undershoot of the line pressure.
摘要翻译：考虑到滑轮旋转引起的离心压力，控制系统控制施加于CVT的管路压力。控制系统确定离心压力是否大于仅由滑轮传递来自发动机的输入转矩的预定值。当确定为肯定时，用于操作管路压力控制阀的占空比的下限从线性范围的下限切换到0％占空比。因此，实际的传输比控制范围扩大，同时防止管路压力的下冲。

7. 发明授权

US6007452A Line pressure control system for continuously variable transmission accounting for input load changes caused by inertia during shifting 失效
标题翻译：用于无级变速器的线路压力控制系统，用于计算变速期间由惯性引起的输入负载变化
公开(公告)号：US6007452A
公开(公告)日：1999-12-28
申请号：US113567
申请日：1998-07-10
申请人： Makoto Sawada , Hirofumi Okahara
发明人： Makoto Sawada , Hirofumi Okahara
IPC分类号： F16H9/00 , F16H61/04 , F16H61/662
CPC分类号： F16H61/66259 , Y10T477/624 , Y10T477/69395 , Y10T477/693958 , Y10T477/693964
摘要： A control system for a CVT comprises a controller arranged to compute an engine revolution condition on the basis of an engine revolution speed indicative signal, to compute actual and estimated engine outputs on the basis of the engine revolution condition, to compute a rotational change condition of the drive system, to compute an actual input load change amount caused by the inertia by multiplying the actual rotational change condition detection value by a predetermined inertial constant, to compute an estimated input load change amount by multiplying the estimated rotational change condition detection value by a predetermined inertia coefficient, to select larger one of the actual input load change amount and the estimated input load change amount as the input load change amount for outputting a command signal, and to output the command signal to a line pressure duty valve on the basis of the engine output and the selected input load change amount so as to further accurately control a line pressure.
摘要翻译：用于CVT的控制系统包括：控制器，被布置成基于发动机转速指示信号计算发动机转速，基于发动机转速来计算实际和估计的发动机输出，以计算发动机转速条件驱动系统，通过将实际旋转变化条件检测值乘以预定惯性常数来计算由惯性引起的实际输入负载变化量，以通过将估计的旋转变化条件检测值乘以一个预定的惯性系数，以选择实际输入负载变化量和估计输入负载变化量中较大的一个作为用于输出指令信号的输入负载变化量，并且基于以下步骤将该指令信号输出到线路压力占空比阀发动机输出和所选择的输入负载变化量，以进一步准确控制 l一线压力。

8. 发明授权

US5152219A Screen process printing apparatus using a screen reinforced by strips 失效
标题翻译：丝网印刷装置使用由条带增强的丝网
公开(公告)号：US5152219A
公开(公告)日：1992-10-06
申请号：US827471
申请日：1992-01-29
申请人： Hideki Adachi , Makoto Sawada , Mokuhei Hashimoto , Hirofumi Shimizu , Jiro Ono , Syunsuke Takagi , Takayuki Umaba , Koichi Mukaegaki , Tsuruo Matsumoto , Tetsu Takahashi
发明人： Hideki Adachi , Makoto Sawada , Mokuhei Hashimoto , Hirofumi Shimizu , Jiro Ono , Syunsuke Takagi , Takayuki Umaba , Koichi Mukaegaki , Tsuruo Matsumoto , Tetsu Takahashi
IPC分类号： B41F15/08 , B41F15/36 , B41F15/40 , H05K3/12
CPC分类号： B41F15/36 , H05K3/1225
摘要： A printing apparatus including: a screen having a printing plate portion and reinforcing strips formed on both sides of the printing plate portion; a stretching device for stretching the screen by applying a predetermined tension thereto in a longitudinal direction of the strips; a squeegee for sliding on the screen in the same direction as the longitudinal direction of the strips, thereby transferring ink onto a surface subjected to printing; and a support table for supporting a material subjected to printing. The squeegee has a width larger than the minimum spacing of the strips on both sides of the printing plate portion. When the squeegee slides on the screen, it presses the printing plate portion and the strips on both sides simultaneously. In printing, the portion of the screen in contact with the surface subjected to printing is maintained flat in the transverse direction. A stretching amount of the screen in the moving direction of the squeegee is equal to a stretching amount of each strip. The screen is not damaged by deformation.
摘要翻译：一种打印设备，包括：具有形成在印版部分两侧的印版部分和加强条的屏幕; 拉伸装置，用于通过在条带的纵向方向上施加预定的张力来拉伸筛网; 用于在与所述条的纵向方向相同的方向上在所述屏幕上滑动的刮板，从而将油墨转印到经受打印的表面上; 以及用于支撑经受印刷的材料的支撑台。刮板的宽度大于印版部两侧的条带的最小间距。当刮板在屏幕上滑动时，它同时按压印版部分和两侧的条。在印刷中，与经过印刷的表面接触的屏幕部分在横向保持平坦。刮板移动方向上的筛网的拉伸量等于每个条带的拉伸量。屏幕不会因变形而损坏。

9. 发明授权

US4968727A Primer composition 失效
标题翻译：底漆组成
公开(公告)号：US4968727A
公开(公告)日：1990-11-06
申请号：US461856
申请日：1990-01-08
申请人： Junichiro Watanabe , Makoto Sawada
发明人： Junichiro Watanabe , Makoto Sawada
IPC分类号： C08K3/36 , C08K5/17 , C08K5/544 , C08L83/04 , C08L83/08 , C09D5/00 , C09D183/08 , C09J5/00 , C09J5/02 , C09J183/00 , C09J183/08
CPC分类号： C09D183/08
摘要： A primer composition which is particularly effective to strongly bond fluorosilicone rubbers to metal, plastics, fibers, and the like, comprising(A) 100 parts by weight of a polyorganosiloxane represented by formula (I): ##EQU1## wherein R.sup.1 represents a substituted or unsubstituted monovalent hydrocarbon group, 10 to 50 mol % of the hydrocarbon groups of R.sup.1 being perfluoroalkyl and 0.01 to 1.0 mol % of the hydrocarbon groups of R.sup.1 being vinyl, and a is a number of from 1.98 to 2.01, and which has a viscosity as measured at 25.degree. C. of 1,000,000 cSt or more;(B) 5 to 100 parts by weight of a silica filler;(C) 0.5 to 50 parts by weight of a compound represented by formula (II): ##STR1## wherein X represents an organosilicon-containing group or a hydrocarbon-containing group, R represents methyl or hydrogen, and n is an integer of 1 or larger; and(D) an organic solvent.
摘要翻译：特别有效地将氟硅氧烷橡胶与金属，塑料，纤维等紧密结合的底漆组合物，其包含（A）100重量份由式（I）表示的聚有机硅氧烷：其中R 1表示取代或未取代的一价烃基，R 1的烃基为10〜50摩尔％为全氟烷基，0.01〜1.0摩尔％的R 1为烃基为乙烯基，a为1.98〜2.01，在25℃下测得的粘度为1,000,000cSt以上; （B）5〜100重量份二氧化硅填料; （C）0.5〜50重量份由式（II）表示的化合物：其中X表示含有机硅基团或含烃基团，R表示甲基或氢原子，n表示 1或更大的整数; 和（D）有机溶剂。

10. 发明授权

US08705322B2 Timepiece device with multiple-hand 有权
标题翻译：钟表装置多手
公开(公告)号：US08705322B2
公开(公告)日：2014-04-22
申请号：US13164842
申请日：2011-06-21
申请人： Makoto Sawada
发明人： Makoto Sawada
IPC分类号： G04C9/00
CPC分类号： G04B19/02 , G04C3/146
摘要： A timepiece device with multiple-hand which can be miniaturized and made thin as a whole has a configuration where a hour hand hour wheel positioned close to an hour hand to which a rotation movement of a 3rd motor via an hour hand gear train mechanism and a functional hand hour wheel positioned close to a functional hand to which a rotation movement of a 4th motor via a functional hand gear train mechanism are arranged on a front side of a support plate, and a 4th wheel positioned close to a second hand and a 2nd wheel positioned close to a minute hand are arranged on a rear side of the support plate.
摘要翻译：具有能够小型化，薄型化的多功能手表装置具有如下构造：时针轮位于接近时针的时刻，第三马达经由时针齿轮机构和功能手轮位于靠近功能手的位置，第四马达通过功能手轮系机构的旋转运动布置在支撑板的前侧，第四轮位于靠近秒针和第二靠近分针的车轮布置在支撑板的后侧。

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