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1. 发明授权

US5594006A Carbostyril derivatives as matrix metalloproteinases inhibitors 失效
标题翻译：卡波他汀衍生物作为基质金属蛋白酶抑制剂
公开(公告)号：US5594006A
公开(公告)日：1997-01-14
申请号：US389645
申请日：1995-02-16
申请人： Makoto Sakamoto , Takeshi Imaoka , Masaaki Motoyama , Yoshihito Yamamoto , Hideki Takasu
发明人： Makoto Sakamoto , Takeshi Imaoka , Masaaki Motoyama , Yoshihito Yamamoto , Hideki Takasu
IPC分类号： C07D215/38 , C07D401/12 , C07D405/12 , C07D409/12 , C07D491/04 , C07D215/227 , A61K31/47
CPC分类号： C07D215/38 , C07D401/12 , C07D405/12 , C07D409/12 , C07D491/04
摘要： This invention provides a carbostyril derivative of the formula (1): ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and n are as defined, or its salt. This carbostyril derivative or its salt possess an excellent matrix metalloproteinases inhibitory action.
摘要翻译：本发明提供式（1）的喹诺酮衍生物：其中R 1，R 2，R 3，R 4，R 5，R 6和n如上所定义，或其盐。该喹诺酮衍生物或其盐具有优异的基质金属蛋白酶抑制作用。

2. 发明授权

US08551999B2 Heterocyclic compound and pharmaceutical composition thereof 失效
标题翻译：杂环化合物及其药物组合物
公开(公告)号：US08551999B2
公开(公告)日：2013-10-08
申请号：US12740684
申请日：2008-10-29
申请人： Takumi Sumida , Fujio Tabusa , Kazuo Sekiguchi , Takeshi Kodama , Koichi Yasumura , Yutaka Kojima , Masaaki Motoyama , Keisuke Miyajima , Kenji Yoshida , Keizo Kan , Makoto Sakamoto , Hideki Takasu , Takashi Nakagawa , Naoto Ohi , Yasuo Harada , Norikazu Hashimoto , Hironori Matsuyama , Masatoshi Iida , Shigekazu Fujita , Tae Fukushima
发明人： Takumi Sumida , Fujio Tabusa , Kazuo Sekiguchi , Takeshi Kodama , Koichi Yasumura , Yutaka Kojima , Masaaki Motoyama , Keisuke Miyajima , Kenji Yoshida , Keizo Kan , Makoto Sakamoto , Hideki Takasu , Takashi Nakagawa , Naoto Ohi , Yasuo Harada , Norikazu Hashimoto , Hironori Matsuyama , Masatoshi Iida , Shigekazu Fujita , Tae Fukushima
IPC分类号： A61K31/496 , A61K31/454 , C07D401/12 , C07D401/14 , C07D405/14 , C07D417/14 , A61K31/506 , C07D403/12
CPC分类号： C07D401/12 , C07D403/12
摘要： The present invention provides a heterocyclic compound represented by General Formula (1): wherein R1 is a group R5—Z1—, etc., Z1 is a lower alkylene group, etc., and R5 is a group represented by General Formula; wherein R13 is a hydrogen atom, etc., m is an integer from 1 to 5; R2 is a hydrogen atom: Y is CH or N: A1 is a heterocyclic ring selected from the group consisting of indolediyl groups, wherein the heterocyclic ring may have at least one substituent: T is a group —CO—, etc.: R3 is a hydrogen atom, etc.: R4 is a lower alkyl group optionally substituted by one or more hydroxy groups, etc.: R3 and R4, together with the nitrogen atom to which they bind, may bind to each other and form a 5- to 10-membered saturated heterocyclic ring, wherein the heterocyclic ring may have at least one substituent. The heterocyclic compound of the present invention has excellent effects of suppressing the production of collagen and/or treating tumors.
摘要翻译：本发明提供由通式（1）表示的杂环化合物：其中R1为R5-Z1-基团等，Z1为低级亚烷基等，R5为通式所示的基团。其中R 13为氢原子等，m为1至5的整数; R2是氢原子：Y是CH或N：A1是选自吲哚二基的杂环，其中杂环可以具有至少一个取代基：T是-CO-等：R3是氢原子等：R4是任选被一个或多个羟基取代的低级烷基等：R 3和R 4与它们所键合的氮原子一起可以彼此结合形成5- 10元饱和杂环，其中杂环可以具有至少一个取代基。本发明的杂环化合物具有抑制胶原蛋白的生成和/或治疗肿瘤的优异效果。

3. 发明申请

US20100004438A1 DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS 失效
标题翻译：二甲苯衍生物作为抗菌剂
公开(公告)号：US20100004438A1
公开(公告)日：2010-01-07
申请号：US12095930
申请日：2006-12-04
申请人： Hironori Matsuyama , Kenji Ohnishi , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Kumi Higuchi , Keisuke Miyajima , Satoshi Yamada , Masaaki Motoyama , Yutaka Kojima , Koichi Yasumura , Takeshi Kodama , Shun Otsuji , Keizo Kan , Takumi Sumida
发明人： Hironori Matsuyama , Kenji Ohnishi , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Kumi Higuchi , Keisuke Miyajima , Satoshi Yamada , Masaaki Motoyama , Yutaka Kojima , Koichi Yasumura , Takeshi Kodama , Shun Otsuji , Keizo Kan , Takumi Sumida
IPC分类号： C07D401/14 , C07D405/14 , C07D413/14 , C07D401/12 , C07D295/155 , C07D211/56 , C07D213/72
CPC分类号： A61K31/496 , A61K31/495
摘要： An object of the present invention is to provide a medicinal drug much improved in anti tumor activity and excellent in safety. According to the present invention, there is provided a medicinal drug containing a compound represented by the following general formula (1) or a salt thereof as an active ingredient: [Formula 1] wherein X1 represents a nitrogen atom or a group —CH═, R1 represents a group -Z-R6, in which Z represents a group —CO—, a group —CH(OH)— or the like, R6 represents a 5- to 15-membered monocyclic, dicyclic or tricyclic saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms or sulfur atoms, R2 represents a hydrogen atom or a halogen atom, Y represents a group —O—, a group —CO—, a group —CH(OH)— or a lower alkylene group, and A represents [Formula 2] wherein R3 represents a hydrogen atom, a lower alkoxy group or the like, p represents 1 or 2, R4 represents an imidazolyl lower alkyl group or the like.
摘要翻译：本发明的目的在于提供一种抗肿瘤活性大大提高的安全性药物。根据本发明，提供含有下述通式（1）表示的化合物或其盐作为有效成分的药物：[式1]其中X1表示氮原子或基团-CH-， R1表示基团-Z-R6，其中Z表示基团-CO-，基团-CH（OH） - 等，R6表示5至15元单环，二环或三环饱和或不饱和杂环基具有1至4个氮原子，氧原子或硫原子，R 2表示氢原子或卤素原子，Y表示基团-O-，基团-CO-，基团-CH（OH） - 或低级亚烷基 A表示[式2]其中R3表示氢原子，低级烷氧基等，p表示1或2，R4表示咪唑基低级烷基等。

4. 发明授权

US08236826B2 Diarylether derivatives as antitumor agents 失效
标题翻译：二元醚衍生物作为抗肿瘤剂
公开(公告)号：US08236826B2
公开(公告)日：2012-08-07
申请号：US12095930
申请日：2006-12-04
申请人： Hironori Matsuyama , Kenji Ohnishi , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Kumi Higuchi , Keisuke Miyajima , Satoshi Yamada , Masaaki Motoyama , Yutaka Kojima , Koichi Yasumura , Takeshi Kodama , Shun Otsuji , Keizo Kan , Takumi Sumida
发明人： Hironori Matsuyama , Kenji Ohnishi , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Kumi Higuchi , Keisuke Miyajima , Satoshi Yamada , Masaaki Motoyama , Yutaka Kojima , Koichi Yasumura , Takeshi Kodama , Shun Otsuji , Keizo Kan , Takumi Sumida
IPC分类号： A61K31/44
CPC分类号： A61K31/496 , A61K31/495
摘要： An object of the present invention is to provide a medicinal drug much improved in anti tumor activity and excellent in safety. According to the present invention, there is provided a medicinal drug containing a compound represented by the following general formula (1) or a salt thereof as an active ingredient: [Formula 1] wherein X1 represents a nitrogen atom or a group —CH═, R1 represents a group —Z—R6, in which Z represents a group —CO—, a group —CH(OH)— or the like, R6 represents a 5- to 15-membered monocyclic, dicyclic or tricyclic saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms or sulfur atoms, R2 represents a hydrogen atom or a halogen atom, Y represents a group —O—, a group —CO—, a group —CH(OH)— or a lower alkylene group, and A represents [Formula 2] wherein R3 represents a hydrogen atom, a lower alkoxy group or the like, p represents 1 or 2, R4 represents an imidazolyl lower alkyl group or the like.
摘要翻译：本发明的目的在于提供一种抗肿瘤活性大大提高的安全性药物。根据本发明，提供了含有下述通式（1）表示的化合物或其盐作为有效成分的药物：[式1]其中X1表示氮原子或基团-CH =， R1表示基团-Z-R6，其中Z表示基团-CO-，基团-CH（OH） - 等，R6表示5至15元单环，二环或三环饱和或不饱和杂环基具有1至4个氮原子，氧原子或硫原子，R 2表示氢原子或卤素原子，Y表示基团-O-，基团-CO-，基团-CH（OH） - 或低级亚烷基 A表示[式2]其中R3表示氢原子，低级烷氧基等，p表示1或2，R4表示咪唑基低级烷基等。

5. 发明申请

US20100261720A1 HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF 失效
标题翻译：杂环化合物及其药物组合物
公开(公告)号：US20100261720A1
公开(公告)日：2010-10-14
申请号：US12740684
申请日：2008-10-29
申请人： Takumi Sumida , Fujio Tabusa , Kazuo Sekiguchi , Takeshi Kodama , Koichi Yasumura , Yutaka Kojima , Masaaki Motoyama , Keisuke Miyajima , Kenji Yoshida , Keizo Kan , Makoto Sakamoto , Hideki Takasu , Takashi Nakagawa , Naoto Ohi , Yasuo Harada , Norikazu Hashimoto , Hironori Matsuyama , Masatoshi Iida , Shigekazu Fujita , Tae Fukushima
发明人： Takumi Sumida , Fujio Tabusa , Kazuo Sekiguchi , Takeshi Kodama , Koichi Yasumura , Yutaka Kojima , Masaaki Motoyama , Keisuke Miyajima , Kenji Yoshida , Keizo Kan , Makoto Sakamoto , Hideki Takasu , Takashi Nakagawa , Naoto Ohi , Yasuo Harada , Norikazu Hashimoto , Hironori Matsuyama , Masatoshi Iida , Shigekazu Fujita , Tae Fukushima
IPC分类号： A61K31/5377 , C07D401/14 , C07D413/14 , A61K31/497 , C07D403/14 , A61P35/00 , A61P43/00
CPC分类号： C07D401/12 , C07D403/12
摘要： The present invention provides a heterocyclic compound represented by General Formula (1): wherein R1 is a group R5—Z1—, etc., Z1 is a lower alkylene group, etc., and R5 is a group represented by General Formula; wherein R13 is a hydrogen atom, etc., m is an integer from 1 to 5; R2 is a hydrogen atom: Y is CH or N: A1 is a heterocyclic ring selected from the group consisting of indolediyl groups, wherein the heterocyclic ring may have at least one substituent: T is a group —CO—, etc.: R3 is a hydrogen atom, etc.: R4 is a lower alkyl group optionally substituted by one or more hydroxy groups, etc.: R3 and R4, together with the nitrogen atom to which they bind, may bind to each other and form a 5- to 10-membered saturated heterocyclic ring, wherein the heterocyclic ring may have at least one substituent. The heterocyclic compound of the present invention has excellent effects of suppressing the production of collagen and/or treating tumors.
摘要翻译：本发明提供由通式（1）表示的杂环化合物：其中R1为R5-Z1-基团等，Z1为低级亚烷基等，R5为通式所示的基团。其中R 13为氢原子等，m为1至5的整数; R2是氢原子：Y是CH或N：A1是选自吲哚二基的杂环，其中杂环可以具有至少一个取代基：T是-CO-等：R3是氢原子等：R4是任选被一个或多个羟基取代的低级烷基等：R 3和R 4与它们所键合的氮原子一起可以彼此结合形成5- 10元饱和杂环，其中杂环可以具有至少一个取代基。本发明的杂环化合物具有抑制胶原蛋白的生成和/或治疗肿瘤的优异效果。

6. 发明申请

US20120238750A1 AROMATIC COMPOUND 审中-公开
标题翻译：芳香化合物
公开(公告)号：US20120238750A1
公开(公告)日：2012-09-20
申请号：US13409090
申请日：2012-02-29
申请人： Tae FUKUSHIMA , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
发明人： Tae FUKUSHIMA , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
IPC分类号： C07D401/12 , C07D413/14 , C07D211/46 , C07D295/155 , C07D405/14
CPC分类号： C07C229/18 , C07C205/38 , C07C217/90 , C07C233/45 , C07C233/75 , C07C271/58 , C07C275/34 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D211/46 , C07D211/58 , C07D211/62 , C07D211/70 , C07D213/75 , C07D239/42 , C07D241/20 , C07D295/185 , C07D295/192 , C07D317/58 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： The compound of the present invention is represented by the following general formula (1): [wherein X1 represents a nitrogen atom or a group —CH═; R1 represents a group —Z—R6, wherein Z represents a group —CO—, a group —CH(OH)—, or the like, and R6 represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; R2 represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group —O—, a group —CO—, a group —CH(OH)—, a lower alkylene group, or the like; and A represents a group or the like, wherein R3 represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R4 represents an imidazolyl lower alkyl group or the like.
摘要翻译：本发明的化合物由以下通式（1）表示：[其中X 1表示氮原子或-CH =; R1表示基团-Z-R6，其中Z表示基团-CO-，基团-CH（OH） - 等，R6表示5至15元单环，双环或三环饱和或具有1-4个氮原子的不饱和杂环基，氧原子或硫原子; R2表示氢原子，卤素原子或低级亚烷基; Y表示基团-O-，基团-CO-，基团-CH（OH） - ，低级亚烷基基团等; A表示基团等，其中R3表示氢原子，低级烷氧基等，p表示1或2，R4表示咪唑基低级烷基等。

7. 发明授权

US08188277B2 Aromatic compounds for suppressing the generation of collagen 失效
标题翻译：抑制胶原蛋白产生的芳香族化合物
公开(公告)号：US08188277B2
公开(公告)日：2012-05-29
申请号：US11659689
申请日：2005-08-03
申请人： Tae Fukushima , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
发明人： Tae Fukushima , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
IPC分类号： C07D241/36 , C07D413/12 , C07D403/12 , C07D221/02 , C07D401/12 , C07D213/62 , A61K31/535 , A61K31/497 , A61K31/445
CPC分类号： C07C229/18 , C07C205/38 , C07C217/90 , C07C233/45 , C07C233/75 , C07C271/58 , C07C275/34 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D211/46 , C07D211/58 , C07D211/62 , C07D211/70 , C07D213/75 , C07D239/42 , C07D241/20 , C07D295/185 , C07D295/192 , C07D317/58 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： The present invention provides a novel compound, which has an excellent effect of suppressing the generation of collagen and less side effects, with being excellent in terms of safety. The compound of the present invention is represented by the following general formula (1): [wherein X1 represents a nitrogen atom or a group —CH═; R1 represents a group —Z—R6, wherein Z represents a group —CO—, a group —CH(OH)—, or the like, and R6 represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; R2 represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group —O—, a group —CO—, a group —CH(OH)—, a lower alkylene group, or the like; and A represents a group or the like, wherein R3 represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R4 represents an imidazolyl lower alkyl group or the like.
摘要翻译：本发明提供了一种新颖的化合物，其具有优异的抑制胶原产生的效果和较少的副作用。本发明的化合物由以下通式（1）表示：[其中X 1表示氮原子或-CH =; R1表示基团-Z-R6，其中Z表示基团-CO-，基团-CH（OH） - 等，R6表示5至15元单环，双环或三环饱和或具有1-4个氮原子的不饱和杂环基，氧原子或硫原子; R2表示氢原子，卤素原子或低级亚烷基; Y表示基团-O-，基团-CO-，基团-CH（OH） - ，低级亚烷基基团等; A表示基团等，其中R3表示氢原子，低级烷氧基等，p表示1或2，R4表示咪唑基低级烷基等。

8. 发明申请

US20070270422A1 Aromatic Compounds 失效
标题翻译：芳香族化合物
公开(公告)号：US20070270422A1
公开(公告)日：2007-11-22
申请号：US11659689
申请日：2005-08-03
申请人： Tae Fukushima , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
发明人： Tae Fukushima , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
IPC分类号： C07D401/14 , A61K31/165 , A61K31/167 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4523 , A61K31/495 , A61K31/496 , A61K31/5375 , A61K31/5377 , A61P11/00 , C07C233/00 , C07C233/92 , C07D211/00 , C07D211/40 , C07D211/56 , C07D241/04 , C07D413/14 , C07D413/02 , C07D241/36
CPC分类号： C07C229/18 , C07C205/38 , C07C217/90 , C07C233/45 , C07C233/75 , C07C271/58 , C07C275/34 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D211/46 , C07D211/58 , C07D211/62 , C07D211/70 , C07D213/75 , C07D239/42 , C07D241/20 , C07D295/185 , C07D295/192 , C07D317/58 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： The present invention provides a novel compound, which has an excellent effect of suppressing the generation of collagen and less side effects, with being excellent in terms of safety. The compound of the present invention is represented by the following general formula (1): [wherein X1 represents a nitrogen atom or a group —CH═; R1 represents a group -Z-R6, wherein Z represents a group —CO—, a group —CH(OH)—, or the like, and R6 represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; R2 represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group —O—, a group —CO—, a group —CH(OH)—, a lower alkylene group, or the like; and A represents a group or the like, wherein R3 represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R4 represents an imidazolyl lower alkyl group or the like.
摘要翻译：本发明提供了一种新颖的化合物，其具有优异的抑制胶原产生的效果和较少的副作用。本发明的化合物由以下通式（1）表示：[其中X 1表示氮原子或基团-CH-; R 1表示基团-ZR 6，其中Z表示-CO-基团，-CH（OH） - 基等基团，R“ 6表示具有1至4个氮原子，氧原子或硫原子的5至15元单环，二环或三环饱和或不饱和杂环基; R 2表示氢原子，卤素原子或低级亚烷基; Y表示基团-O-，基团-CO-，基团-CH（OH） - ，低级亚烷基基团等; A表示基团等，其中R 3表示氢原子，低级烷氧基等，p表示1或2，R 4表示咪唑基低级烷基等。

9. 发明申请

US20050239319A1 Coaxial connector 有权
标题翻译：同轴连接器
公开(公告)号：US20050239319A1
公开(公告)日：2005-10-27
申请号：US11115508
申请日：2005-04-27
申请人： Hideki Takasu
发明人： Hideki Takasu
IPC分类号： H01R4/18 , H01R9/05 , H01R103/00 , H01R4/24
CPC分类号： H01R24/44 , H01R4/184 , H01R9/0518 , H01R2103/00
摘要： A coaxial connector, in which control of impedance is facilitated, and in which fluctuations in impedance are extremely small. The coaxial connector includes an inner contact, having a crimp connection portion which is crimped onto an inner conductor of a coaxial cable, an outer contact, which is crimped onto an outer conductor of the coaxial cable and an insulator (dielectric), which is provided between the inner contact and the outer contract. Concavities are formed in the outer surface of the dielectric at positions corresponding to the crimp connection portion of the inner contact The concavities control the characteristic impedance of the coaxial connector.
摘要翻译：一种同轴连接器，其中阻抗的控制被促进，并且其中阻抗的波动非常小。同轴连接器包括内接触件，其具有压接在同轴电缆的内导体上的压接连接部分，压接在同轴电缆的外导体上的外触点和绝缘体（电介质）内部接触和外部合同之间。在电介质的外表面形成凹部，该位置对应于内触头的压接连接部分。凹部控制同轴连接器的特性阻抗。

10. 发明授权

US5435756A Adapter for two core cable 失效
标题翻译：两芯电缆适配器
公开(公告)号：US5435756A
公开(公告)日：1995-07-25
申请号：US274057
申请日：1994-07-12
申请人： Hideki Takasu
发明人： Hideki Takasu
IPC分类号： H01R9/05 , H01R13/40 , H01R17/04
CPC分类号： H01R9/0518 , H01R24/542 , H01R2103/00 , H01R9/035
摘要： One end of a two-core twisted pair cable 30 having two twisted wires 32 and 34 in a common jacket 36 is prepared. An insert 20 having a pair of semicylindrical halves 22a and 22b connected by a hinge 21 in which a central groove 25 and a branched groove 26 are formed is used. An insert subassembly is prepared by placing one wire 32 connected to the central contact in the central groove 25 of the insert 20, and by placing the other wire 34 in the branched groove 26 and bringing outside its exposed conductor 38. This insert subassembly is inserted in the outer ferrule 13 of the metal shell 12 of the BNC connector 10, after which the ferrule is crimped, thus connecting the conductor 38 to the metal shell 12.
摘要翻译：制备在公共护套36中具有两条绞合线32和34的双芯双绞线电缆30的一端。使用具有通过铰链21连接的一对半圆柱半部22a和22b的插入件20，其中形成有中心槽25和分支槽26。通过将连接到中心触点的一个线32放置在插入件20的中心凹槽25中，并且将另一个线34放置在分支槽26中并且将其外露在其暴露的导体38之外来准备插入子组件。该插入子组件被插入在BNC连接器10的金属外壳12的外套圈13中，之后套圈被压接，从而将导体38连接到金属壳12。

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