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1. 发明授权

US08946437B2 4-(methylaminophenoxy)pyrdin-3-yl-benzamide derivatives for treating cancer 有权
标题翻译： 4-（甲基氨基苯氧基）哒嗪-3-基 - 苯甲酰胺衍生物用于治疗癌症
公开(公告)号：US08946437B2
公开(公告)日：2015-02-03
申请号：US13877276
申请日：2011-10-03
申请人： Takashi Nakagawa , Makoto Sakamoto , Kazuya Yamaguchi , Yuki Terauchi , Masamichi Shirakura , Yasuo Harada , Yutaka Kojima , Takumi Sumida
发明人： Takashi Nakagawa , Makoto Sakamoto , Kazuya Yamaguchi , Yuki Terauchi , Masamichi Shirakura , Yasuo Harada , Yutaka Kojima , Takumi Sumida
IPC分类号： A01N43/40 , A61K31/44 , C07D211/72 , C07D211/84 , C07D213/63 , C07D213/70 , C07D213/72 , C07D213/78 , C07D213/76 , C07D213/75
CPC分类号： C07D213/75 , C07D213/76
摘要： The present invention provides a novel compound having an excellent antitumor effect, stability and metabolic stability. The compound of the present invention is represented by the following general formula (1) wherein R1 represents a halogen atom, an aryl group, an aryloxy group or a lower alkyl group optionally substituted with one or more halogen atoms; R2 represents hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group; and; m represents an integer of 1 to 3; provided that when m represents 2 or 3, R1s are the same or different.
摘要翻译：本发明提供具有优异的抗肿瘤效果，稳定性和代谢稳定性的新型化合物。本发明化合物由以下通式（1）表示，其中R 1表示卤素原子，芳基，芳氧基或任选被一个或多个卤素原子取代的低级烷基; R2表示氢原子，卤素原子，低级烷基或低级烷氧基; 和; m表示1〜3的整数，条件是当m表示2或3时，R 1相同或不同。

2. 发明授权

US08638091B2 Rotary eddy current testing probe device 有权
标题翻译：旋转涡流检测探头装置
公开(公告)号：US08638091B2
公开(公告)日：2014-01-28
申请号：US13286429
申请日：2011-11-01
申请人： Takashi Hibino , Takashi Fujimoto , Shigeki Namekata , Keisuke Komatsu , Yoshiyuki Nakao , Makoto Takata , Makoto Sakamoto
发明人： Takashi Hibino , Takashi Fujimoto , Shigeki Namekata , Keisuke Komatsu , Yoshiyuki Nakao , Makoto Takata , Makoto Sakamoto
IPC分类号： G01N27/90
CPC分类号： G01N27/902 , G01N27/904
摘要： A rotary eddy current flaw detection probe device has a plurality of Θ-shaped eddy current flaw detection probes attached in a rotating disc for detecting flaws in all directions regardless of the flaw direction. Four Θ-shaped eddy current testing probes P11 to P22 are arranged around the rotation center Ds1 of a rotating disc 111 and are embedded in the disc 111. The coil planes of detector coils Ds11 to Ds22 of the testing probes P11 to P22 are parallel with each other, and are perpendicular to the rotation plane of the rotating disc 111. The coil planes of the detector coils incline at an angle θ relative to a line Y passing through the centers Ps11 and Ps12 of the probes P11 and P12. The detector coils Dc11 and Dc12 are cumulatively connected to each other and the detector coils Dc21 and Dc22 are differentially connected to each other.
摘要翻译：旋转涡流探伤探针装置具有附接在旋转盘中的多个Theta形涡流探伤探针，用于检测各个方向的瑕疵，而不管瑕疵方向如何。四个Theta形涡电流测试探针P11至P22围绕旋转盘111的旋转中心Ds1布置并嵌入到盘111中。测试探针P11至P22的检测器线圈Ds11至Ds22的线圈平面与彼此垂直于旋转盘111的旋转平面。检测器线圈的线圈面相对于穿过探针P11和P12的中心Ps11和Ps12的线Y以一定角度倾斜。检测器线圈Dc11和Dc12彼此累积连接，检测线圈Dc21和Dc22彼此差分地连接。

3. 发明授权

US08551999B2 Heterocyclic compound and pharmaceutical composition thereof 失效
标题翻译：杂环化合物及其药物组合物
公开(公告)号：US08551999B2
公开(公告)日：2013-10-08
申请号：US12740684
申请日：2008-10-29
申请人： Takumi Sumida , Fujio Tabusa , Kazuo Sekiguchi , Takeshi Kodama , Koichi Yasumura , Yutaka Kojima , Masaaki Motoyama , Keisuke Miyajima , Kenji Yoshida , Keizo Kan , Makoto Sakamoto , Hideki Takasu , Takashi Nakagawa , Naoto Ohi , Yasuo Harada , Norikazu Hashimoto , Hironori Matsuyama , Masatoshi Iida , Shigekazu Fujita , Tae Fukushima
发明人： Takumi Sumida , Fujio Tabusa , Kazuo Sekiguchi , Takeshi Kodama , Koichi Yasumura , Yutaka Kojima , Masaaki Motoyama , Keisuke Miyajima , Kenji Yoshida , Keizo Kan , Makoto Sakamoto , Hideki Takasu , Takashi Nakagawa , Naoto Ohi , Yasuo Harada , Norikazu Hashimoto , Hironori Matsuyama , Masatoshi Iida , Shigekazu Fujita , Tae Fukushima
IPC分类号： A61K31/496 , A61K31/454 , C07D401/12 , C07D401/14 , C07D405/14 , C07D417/14 , A61K31/506 , C07D403/12
CPC分类号： C07D401/12 , C07D403/12
摘要： The present invention provides a heterocyclic compound represented by General Formula (1): wherein R1 is a group R5—Z1—, etc., Z1 is a lower alkylene group, etc., and R5 is a group represented by General Formula; wherein R13 is a hydrogen atom, etc., m is an integer from 1 to 5; R2 is a hydrogen atom: Y is CH or N: A1 is a heterocyclic ring selected from the group consisting of indolediyl groups, wherein the heterocyclic ring may have at least one substituent: T is a group —CO—, etc.: R3 is a hydrogen atom, etc.: R4 is a lower alkyl group optionally substituted by one or more hydroxy groups, etc.: R3 and R4, together with the nitrogen atom to which they bind, may bind to each other and form a 5- to 10-membered saturated heterocyclic ring, wherein the heterocyclic ring may have at least one substituent. The heterocyclic compound of the present invention has excellent effects of suppressing the production of collagen and/or treating tumors.
摘要翻译：本发明提供由通式（1）表示的杂环化合物：其中R1为R5-Z1-基团等，Z1为低级亚烷基等，R5为通式所示的基团。其中R 13为氢原子等，m为1至5的整数; R2是氢原子：Y是CH或N：A1是选自吲哚二基的杂环，其中杂环可以具有至少一个取代基：T是-CO-等：R3是氢原子等：R4是任选被一个或多个羟基取代的低级烷基等：R 3和R 4与它们所键合的氮原子一起可以彼此结合形成5- 10元饱和杂环，其中杂环可以具有至少一个取代基。本发明的杂环化合物具有抑制胶原蛋白的生成和/或治疗肿瘤的优异效果。

4. 发明申请

US20120161758A1 EDDY CURRENT TESTING METHOD AND EDDY CURRENT TESTING APPARATUS 有权
标题翻译： EDDY电流测试方法和EDDY电流测试装置
公开(公告)号：US20120161758A1
公开(公告)日：2012-06-28
申请号：US13140845
申请日：2009-12-14
申请人： Takashi Hibino , Takashi Fujimoto , Keisuke Komatsu , Yoshiyuki Nakao , Makoto Takata , Makoto Sakamoto
发明人： Takashi Hibino , Takashi Fujimoto , Keisuke Komatsu , Yoshiyuki Nakao , Makoto Takata , Makoto Sakamoto
IPC分类号： G01R33/12
CPC分类号： G01N27/902 , G01N27/82
摘要： In an eddy current testing method which involves using a rotatable eddy current testing probe in which a detection coil is arranged within an exciting coil, a change in detection sensitivity (a deviation of detection sensitivity) which changes depending on the rotational position of the detection coil is reduced. The eddy current testing probe includes an exciting coil EC1, a detection coil DC1, an exciting coil EC2 and a detection coil DC2, which are mounted on a disk DS. The eddy current testing probe is placed so as to face a circumferential surface of an object to be inspected T, which is in the shape of a circular cylinder, and the disk DS is rotated. Then, the distance (liftoff) between the detection coils DC1 and DC2 and an inspection surface changes. Therefore, also the detection sensitivity to a flaw signal changes. To reduce the change in detection sensitivity, the detection sensitivity is adjusted by detecting the rotational position (rotational angle) of the detection coils DC1 and DC2.
摘要翻译：在涡电流测试方法中，涉及使用其中检测线圈布置在励磁线圈内的可旋转涡流测试探针，检测灵敏度的变化（检测灵敏度的偏差）根据检测线圈的旋转位置而变化降低了。涡电流测试探头包括安装在盘DS上的励磁线圈EC1，检测线圈DC1，励磁线圈EC2和检测线圈DC2。将涡电流测试探针放置成面对被检查物体T的圆周表面，该圆形表面呈圆柱形，圆盘DS旋转。然后，检测线圈DC1和DC2之间的距离（剥离）和检查面发生变化。因此，对缺陷信号的检测灵敏度也会发生变化。为了减小检测灵敏度的变化，通过检测检测线圈DC1和DC2的旋转位置（旋转角度）来调节检测灵敏度。

5. 发明授权

US5003200A Programmable logic device having programmable wiring for connecting adjacent programmable logic elements through a single switch station 失效
标题翻译：具有用于通过单个开关站连接相邻可编程逻辑元件的可编程布线的可编程逻辑器件
公开(公告)号：US5003200A
公开(公告)日：1991-03-26
申请号：US408523
申请日：1989-09-18
申请人： Makoto Sakamoto
发明人： Makoto Sakamoto
IPC分类号： H03K19/177
CPC分类号： H03K19/17736 , H03K19/17704
摘要： There is provided a programmable logic device (PLD) which includes a programmable wiring, the programmable wiring comprising: a plurality of switch stations (SS), first wirings each for directly connecting some terminals among input/output terminals of said SSs to input/output terminals of adjacent programmable logic elements (PLE), and second wirings each for directly connecting some terminals among the input/output terminals of said SSs to input/output terminals of the adjacent SS. Hereby, the numbers of involved switches, through which associated signals pass, can be reduced.

6. 发明授权

US09291599B2 Magnetic testing method and apparatus 有权
标题翻译：磁测试方法及装置
公开(公告)号：US09291599B2
公开(公告)日：2016-03-22
申请号：US14238958
申请日：2012-08-15
申请人： Toshiyuki Suzuma , Yoshiyuki Nakao , Makoto Sakamoto , Yoshiyuki Oota
发明人： Toshiyuki Suzuma , Yoshiyuki Nakao , Makoto Sakamoto , Yoshiyuki Oota
IPC分类号： G01N27/82 , G01N27/83 , G01N27/90
CPC分类号： G01N27/82 , G01N27/83 , G01N27/902
摘要： A magnetic testing apparatus 100 according to the present invention comprises: a first magnetizing device 1 for applying a DC bias magnetic field to a test object P in substantially parallel to the direction in which a flaw F to be detected extends; a second magnetizing device 2 for applying an AC magnetic field to the test object P substantially perpendicularly to the direction in which the flaw F to be detected extends; and a detecting device 3 for detecting leakage flux produced by the magnetization of the test object P accomplished by the first magnetizing device 1 and the second magnetizing device 2.
摘要翻译：根据本发明的磁性测试装置100包括：第一磁化装置1，用于将基本上平行于待检测的缺陷F的方向延伸的测试对象P施加直流偏置磁场; 第二磁化装置2，用于将大致垂直于待检测的缺陷F的方向延伸的测试对象P的交流磁场施加; 以及检测装置3，用于检测由第一磁化装置1和第二磁化装置2实现的被测试物体P的磁化产生的漏磁通。

7. 发明授权

US08803516B2 Eddy current testing method and apparatus for inspecting an object for flaws 有权
标题翻译：用于检查物体的涡流检测方法和装置的缺陷
公开(公告)号：US08803516B2
公开(公告)日：2014-08-12
申请号：US13140845
申请日：2009-12-14
申请人： Takashi Hibino , Takashi Fujimoto , Keisuke Komatsu , Yoshiyuki Nakao , Makoto Takata , Makoto Sakamoto
发明人： Takashi Hibino , Takashi Fujimoto , Keisuke Komatsu , Yoshiyuki Nakao , Makoto Takata , Makoto Sakamoto
IPC分类号： G01R33/12 , G01N27/90 , G01N27/82
CPC分类号： G01N27/902 , G01N27/82
摘要： In an eddy current testing method which involves using a rotatable eddy current testing probe in which a detection coil is arranged within an exciting coil, a change in detection sensitivity (a deviation of detection sensitivity) which changes depending on the rotational position of the detection coil is reduced. The eddy current testing probe includes an exciting coil EC1, a detection coil DC1, an exciting coil EC2 and a detection coil DC2, which are mounted on a disk DS. The eddy current testing probe is placed so as to face a circumferential surface of an object to be inspected T, which is in the shape of a circular cylinder, and the disk DS is rotated. Then, the distance (liftoff) between the detection coils DC1 and DC2 and an inspection surface changes. Therefore, also the detection sensitivity to a flaw signal changes. To reduce the change in detection sensitivity, the detection sensitivity is adjusted by detecting the rotational position (rotational angle) of the detection coils DC1 and DC2.
摘要翻译：在涡电流测试方法中，涉及使用其中检测线圈布置在励磁线圈内的可旋转涡流测试探针，检测灵敏度的变化（检测灵敏度的偏差）根据检测线圈的旋转位置而变化降低了。涡电流测试探头包括安装在盘DS上的励磁线圈EC1，检测线圈DC1，励磁线圈EC2和检测线圈DC2。将涡电流测试探针放置成面对被检查物体T的圆周表面，该圆形表面呈圆柱形，圆盘DS旋转。然后，检测线圈DC1和DC2之间的距离（剥离）和检查面发生变化。因此，对缺陷信号的检测灵敏度也会发生变化。为了减小检测灵敏度的变化，通过检测检测线圈DC1和DC2的旋转位置（旋转角度）来调节检测灵敏度。

8. 发明授权

US08438926B2 Method of evaluating fastening state of threaded joint of pipes or tubes, method for fastening threaded joint of pipes or tubes, and apparatus for evaluating fastening state of threaded joint of pipes or tubes 有权
标题翻译：评估管道螺纹接头的紧固状态的方法，管道或管子的螺纹接头的方法以及用于评估管道或管道的螺纹接头的紧固状态的装置
公开(公告)号：US08438926B2
公开(公告)日：2013-05-14
申请号：US13239610
申请日：2011-09-22
申请人： Ikuji Hoshino , Masaki Yamano , Makoto Sakamoto , Keiichi Nakamura , Jun Masubuchi , Kenta Sakai
发明人： Ikuji Hoshino , Masaki Yamano , Makoto Sakamoto , Keiichi Nakamura , Jun Masubuchi , Kenta Sakai
IPC分类号： G01N29/24 , G01N29/07 , G01N29/09
CPC分类号： G01N29/11 , F16L15/004 , F16L2201/10 , G01N2291/02827 , G01N2291/0423 , G01N2291/044 , G01N2291/2636 , G01N2291/2691
摘要： The present invention provides a method which allows simply, easily and accurately evaluating the fastening state of shoulder parts of a threaded joint for use as a joint of pipes or tubes, such as OCTG, during fastening or after fastening. The fastening state evaluation method for a threaded joint 100 of pipes or tubes according to the present invention is characterized in that it transmits ultrasonic surface waves from the internal surface of either one of the pin 1 and the box 2 toward the internal surface of the other one of the pin 1 and the box 2 through the shoulder parts 13, 23 of the pin 1 and the box 2, and on the basis of the transmitted wave intensity or the reflected wave intensity thereof, determines whether or not the fastening state of the threaded joint 100 is satisfactory.
摘要翻译：本发明提供了一种方法，其可以简单，容易且准确地评估在紧固期间或紧固之后用作管道或管（如OCTG）的接头的螺纹接头的肩部的紧固状态。根据本发明的管或螺纹接头100的紧固状态评估方法的特征在于，其从销1和盒2中的任一个的内表面向另一个的内表面传输超声表面波通过销1和盒子2的肩部13,23的销1和盒2中的一个，并且基于透射波强度或其反射波强度，确定是否将紧固状态螺纹接头100是令人满意的。

9. 发明授权

US08188277B2 Aromatic compounds for suppressing the generation of collagen 失效
标题翻译：抑制胶原蛋白产生的芳香族化合物
公开(公告)号：US08188277B2
公开(公告)日：2012-05-29
申请号：US11659689
申请日：2005-08-03
申请人： Tae Fukushima , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
发明人： Tae Fukushima , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
IPC分类号： C07D241/36 , C07D413/12 , C07D403/12 , C07D221/02 , C07D401/12 , C07D213/62 , A61K31/535 , A61K31/497 , A61K31/445
CPC分类号： C07C229/18 , C07C205/38 , C07C217/90 , C07C233/45 , C07C233/75 , C07C271/58 , C07C275/34 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D211/46 , C07D211/58 , C07D211/62 , C07D211/70 , C07D213/75 , C07D239/42 , C07D241/20 , C07D295/185 , C07D295/192 , C07D317/58 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： The present invention provides a novel compound, which has an excellent effect of suppressing the generation of collagen and less side effects, with being excellent in terms of safety. The compound of the present invention is represented by the following general formula (1): [wherein X1 represents a nitrogen atom or a group —CH═; R1 represents a group —Z—R6, wherein Z represents a group —CO—, a group —CH(OH)—, or the like, and R6 represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; R2 represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group —O—, a group —CO—, a group —CH(OH)—, a lower alkylene group, or the like; and A represents a group or the like, wherein R3 represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R4 represents an imidazolyl lower alkyl group or the like.
摘要翻译：本发明提供了一种新颖的化合物，其具有优异的抑制胶原产生的效果和较少的副作用。本发明的化合物由以下通式（1）表示：[其中X 1表示氮原子或-CH =; R1表示基团-Z-R6，其中Z表示基团-CO-，基团-CH（OH） - 等，R6表示5至15元单环，双环或三环饱和或具有1-4个氮原子的不饱和杂环基，氧原子或硫原子; R2表示氢原子，卤素原子或低级亚烷基; Y表示基团-O-，基团-CO-，基团-CH（OH） - ，低级亚烷基基团等; A表示基团等，其中R3表示氢原子，低级烷氧基等，p表示1或2，R4表示咪唑基低级烷基等。

10. 发明申请

US20070270422A1 Aromatic Compounds 失效
标题翻译：芳香族化合物
公开(公告)号：US20070270422A1
公开(公告)日：2007-11-22
申请号：US11659689
申请日：2005-08-03
申请人： Tae Fukushima , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
发明人： Tae Fukushima , Shuji Matsumura , Noriaki Takemura , Hideaki Satou , Nobuaki Ito , Takuya Shitsuta , Hironori Tsutsui , Michinori Tanaka , Keizo Kan , Hitoshi Nagao , Kenji Watanabe , Kuninori Tai , Takashi Nakagawa , Hideki Takasu , Makoto Sakamoto , Keisuke Miyajima , Satoshi Yamada , Yutaka Kojima , Koichi Yasumura , Naoto Ohi , Mitsuhiro Okuno , Kazuhisa Sugiyama , Kunihiko Kiyono , Takashi Suzuki , Seiji Akamatsu , Takeshi Kodama , Yasuo Yanagihara , Takumi Sumida
IPC分类号： C07D401/14 , A61K31/165 , A61K31/167 , A61K31/44 , A61K31/4427 , A61K31/445 , A61K31/4523 , A61K31/495 , A61K31/496 , A61K31/5375 , A61K31/5377 , A61P11/00 , C07C233/00 , C07C233/92 , C07D211/00 , C07D211/40 , C07D211/56 , C07D241/04 , C07D413/14 , C07D413/02 , C07D241/36
CPC分类号： C07C229/18 , C07C205/38 , C07C217/90 , C07C233/45 , C07C233/75 , C07C271/58 , C07C275/34 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D211/46 , C07D211/58 , C07D211/62 , C07D211/70 , C07D213/75 , C07D239/42 , C07D241/20 , C07D295/185 , C07D295/192 , C07D317/58 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14
摘要： The present invention provides a novel compound, which has an excellent effect of suppressing the generation of collagen and less side effects, with being excellent in terms of safety. The compound of the present invention is represented by the following general formula (1): [wherein X1 represents a nitrogen atom or a group —CH═; R1 represents a group -Z-R6, wherein Z represents a group —CO—, a group —CH(OH)—, or the like, and R6 represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; R2 represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group —O—, a group —CO—, a group —CH(OH)—, a lower alkylene group, or the like; and A represents a group or the like, wherein R3 represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R4 represents an imidazolyl lower alkyl group or the like.
摘要翻译：本发明提供了一种新颖的化合物，其具有优异的抑制胶原产生的效果和较少的副作用。本发明的化合物由以下通式（1）表示：[其中X 1表示氮原子或基团-CH-; R 1表示基团-ZR 6，其中Z表示-CO-基团，-CH（OH） - 基等基团，R“ 6表示具有1至4个氮原子，氧原子或硫原子的5至15元单环，二环或三环饱和或不饱和杂环基; R 2表示氢原子，卤素原子或低级亚烷基; Y表示基团-O-，基团-CO-，基团-CH（OH） - ，低级亚烷基基团等; A表示基团等，其中R 3表示氢原子，低级烷氧基等，p表示1或2，R 4表示咪唑基低级烷基等。

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