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1. 发明申请

US20090156779A1 BACTERIUM CAPABLE OF PRODUCING ORGANIC ACID, AND METHOD FOR PRODUCTION OF ORGANIC ACID 有权
标题翻译：生产有机酸的细菌和生产有机酸的方法
公开(公告)号：US20090156779A1
公开(公告)日：2009-06-18
申请号：US12280426
申请日：2007-02-23
申请人： Makoto Murase , Ryusuke Aoyama , Akiko Sakamoto , Sanae Sato , Madoka Yonekura , Shuichi Yunomura , Kenji Yamagishi , Keita Fukui , Chie Koseki , Jun Nakamura , Hiroyuki Kojima
发明人： Makoto Murase , Ryusuke Aoyama , Akiko Sakamoto , Sanae Sato , Madoka Yonekura , Shuichi Yunomura , Kenji Yamagishi , Keita Fukui , Chie Koseki , Jun Nakamura , Hiroyuki Kojima
IPC分类号： C12P7/46 , C12N1/20 , C08G63/02
CPC分类号： C12P7/46
摘要： Provided is a bacterium which is capable of producing an organic acid and is modified so as to have an enhanced 2-oxoglutarate dehydrogenase activity as compared with that of an unmodified strain. An organic acid such as succinic acid can be produced by culturing the bacterium.
摘要翻译：本发明提供一种能够产生有机酸的细菌，并且与未改变的菌株相比被改性以具有增强的2-氧戊二酸脱氢酶活性。可以通过培养细菌来生产琥珀酸等有机酸。

2. 发明授权

US07993888B2 Bacterium having enhanced 2-oxoglutarate dehydrogenase activity 有权
标题翻译：具有增强的2-氧戊二酸脱氢酶活性的细菌
公开(公告)号：US07993888B2
公开(公告)日：2011-08-09
申请号：US12280426
申请日：2007-02-23
申请人： Makoto Murase , Ryusuke Aoyama , Akiko Sakamoto , Sanae Sato , Madoka Yonekura , Shuichi Yunomura , Kenji Yamagishi , Keita Fukui , Chie Koseki , Jun Nakamura , Hiroyuki Kojima
发明人： Makoto Murase , Ryusuke Aoyama , Akiko Sakamoto , Sanae Sato , Madoka Yonekura , Shuichi Yunomura , Kenji Yamagishi , Keita Fukui , Chie Koseki , Jun Nakamura , Hiroyuki Kojima
IPC分类号： C12P7/46 , C12P21/06 , C12N1/20 , C12N15/00 , C12N9/04 , C07H21/02 , C07H21/04 , C08G63/02
CPC分类号： C12P7/46
摘要： Provided is a bacterium which is capable of producing an organic acid and is modified so as to have an enhanced 2-oxoglutarate dehydrogenase activity as compared with that of an unmodified strain. An organic acid such as succinic acid can be produced by culturing the bacterium.
摘要翻译：本发明提供一种能够产生有机酸的细菌，并且与未改变的菌株相比被改性以具有增强的2-氧戊二酸脱氢酶活性。可以通过培养细菌来生产琥珀酸等有机酸。

3. 发明申请

US20120073017A1 METHOD FOR PRODUCING CHRYSANTHEMUM PLANT HAVING PETALS CONTAINING MODIFIED ANTHOCYANIN 有权
标题翻译：生产具有改性蒽醌类化合物的化学植物的方法
公开(公告)号：US20120073017A1
公开(公告)日：2012-03-22
申请号：US13265791
申请日：2010-03-09
申请人： Naonobu Noda , Ryutaro Aida , Sanae Sato , Akemi Ohmiya , Yoshikazu Tanaka
发明人： Naonobu Noda , Ryutaro Aida , Sanae Sato , Akemi Ohmiya , Yoshikazu Tanaka
IPC分类号： C12N15/82 , A01H5/02 , C12N15/113 , A01H5/00
CPC分类号： C12N15/825 , C12N9/1029 , C12N15/8243
摘要： Disclosed are a method for controlling flavonoid synthesis in a chrysanthemum plant or non-chrysanthemum plant by genetic recombination technology using a transcriptional regulatory region useful for altering flower color, a method for modifying anthocyanins, a method for producing a chrysanthemum plant or non-chrysanthemum plant containing modified anthocyanins in the petals thereof, and a chrysanthemum plant or non-chrysanthemum plant, progeny thereof, or vegetatively propagated products, part or tissue thereof transformed with the regulatory region. In the method according to the present invention, an expression vector or expression cassette containing a transcriptional regulatory region of perilla anthocyanin 3-acyltransferase gene, such as a nucleic acid containing the nucleotide sequence indicated in SEQ ID NO. 1, or a transcriptional regulatory region of pansy F3′5′H gene, such as the nucleotide sequence indicated in SEQ ID NO. 15, is used.
摘要翻译：公开了通过使用可用于改变花色的转录调节区域的基因重组技术控制菊花植物或非菊花植物中黄酮类化合物的方法，改性花青素的方法，菊花植物或非菊菊植物的制备方法在其花瓣中含有改性的花青素，以及菊花植物或非菊花植物，其后代或经调节区转化的营养繁殖产物，其部分或组织。在本发明的方法中，含有紫苏花青素3-酰基转移酶基因的转录调节区的表达载体或表达盒，例如含有SEQ ID NO：1所示的核苷酸序列的核酸。 1，或三色堇F3'5'H基因的转录调节区，如SEQ ID NO：1所示的核苷酸序列。 15，被使用。

4. 发明授权

US09074215B2 Method for production of chrysanthemum plant having delphinidin-containing petals 有权
标题翻译：生产含有花翠素的菊花植物的方法
公开(公告)号：US09074215B2
公开(公告)日：2015-07-07
申请号：US13265688
申请日：2010-03-09
申请人： Naonobu Noda , Ryutaro Aida , Sanae Sato , Akemi Ohmiya , Yoshikazu Tanaka
发明人： Naonobu Noda , Ryutaro Aida , Sanae Sato , Akemi Ohmiya , Yoshikazu Tanaka
IPC分类号： C12N15/82 , C12N9/02 , A01H5/02
CPC分类号： C12N15/8243 , A01H5/02 , A01H6/1424 , C12N9/0071 , C12N15/825
摘要： Disclosed are: a method for producing a chrysanthemum plant having delphinidin-containing petals using a transcriptional regulatory region for a chrysanthemum-derived flavanone 3-hydroxylase (F3H) gene; and a chrysanthemum plant, a progeny or a vegetative proliferation product of the plant, or a part or a tissue of the plant, the progeny or the vegetative proliferation product, and particularly a petal or a cut flower of the plant. In the method for producing a chrysanthemum plant having delphinidin-containing petals, a flavonoid 3′,5′-hydroxylase (F3′5′H) is caused to be expressed in a chrysanthemum plant using a transcriptional regulatory region for a chrysanthemum-derived flavanone 3-hydroxylase (F3H) gene.
摘要翻译：公开了一种使用菊花衍生的黄烷酮3-羟化酶（F3H）基因的转录调节区域产生具有花翠素的花瓣的菊花植物的方法。菊花植物，植物的后代或营养增殖产物，植物的一部分或组织，子代或营养增殖产物，特别是植物的花瓣或切花。在具有含花翠素的花瓣的菊花植物的制造方法中，使用菊花衍生的黄烷酮的转录调节区域在菊花植物中表达黄酮3'，5'-羟化酶（F3'5'H） 3-羟化酶（F3H）基因。

5. 发明授权

US08871998B2 Method for producing chrysanthemum plant having petals containing modified anthocyanin 有权
标题翻译：生产含有改性花青素花瓣的菊花植物的方法
公开(公告)号：US08871998B2
公开(公告)日：2014-10-28
申请号：US13265791
申请日：2010-03-09
申请人： Naonobu Noda , Ryutaro Aida , Sanae Sato , Akemi Ohmiya , Yoshikazu Tanaka
发明人： Naonobu Noda , Ryutaro Aida , Sanae Sato , Akemi Ohmiya , Yoshikazu Tanaka
IPC分类号： C12N15/09 , C12N15/63 , C12N15/82 , C12N5/04 , C12N9/10
CPC分类号： C12N15/825 , C12N9/1029 , C12N15/8243
摘要： Disclosed are a method for controlling flavonoid synthesis in a chrysanthemum plant or non-chrysanthemum plant by genetic recombination technology using a transcriptional regulatory region useful for altering flower color, a method for modifying anthocyanins, a method for producing a chrysanthemum plant or non-chrysanthemum plant containing modified anthocyanins in the petals thereof, and a chrysanthemum plant or non-chrysanthemum plant, progeny thereof, or vegetatively propagated products, part or tissue thereof transformed with the regulatory region. In the method according to the present invention, an expression vector or expression cassette containing a transcriptional regulatory region of perilla anthocyanin 3-acyltransferase gene, such as a nucleic acid containing the nucleotide sequence indicated in SEQ ID NO. 1, or a transcriptional regulatory region of pansy F3′5′H gene, such as the nucleotide sequence indicated in SEQ ID NO. 15, is used.
摘要翻译：公开了通过使用可用于改变花色的转录调节区域的基因重组技术控制菊花植物或非菊花植物中黄酮类化合物的方法，改性花青素的方法，菊花植物或非菊菊植物的制备方法在其花瓣中含有改性的花青素，以及菊花植物或非菊花植物，其后代或经调节区转化的营养繁殖产物，其部分或组织。在本发明的方法中，含有紫苏花青素3-酰基转移酶基因的转录调节区的表达载体或表达盒，例如含有SEQ ID NO：1所示的核苷酸序列的核酸。 1，或三色堇F3'5'H基因的转录调节区，如SEQ ID NO：1所示的核苷酸序列。 15，被使用。

6. 发明申请

US20120096589A1 METHOD FOR PRODUCTION OF CHRYSANTHEMUM PLANT HAVING DELPHINIDIN-CONTAINING PETALS 有权
标题翻译：用于生产含有含有蝶啶含量的石蜡的植物的方法
公开(公告)号：US20120096589A1
公开(公告)日：2012-04-19
申请号：US13265688
申请日：2010-03-09
申请人： Naonobu Noda , Ryutaro Aida , Sanae Sato , Akemi Ohmiya , Yoshikazu Tanaka
发明人： Naonobu Noda , Ryutaro Aida , Sanae Sato , Akemi Ohmiya , Yoshikazu Tanaka
IPC分类号： A01H5/02 , A01H5/00 , C12N5/04 , A01H1/00
CPC分类号： C12N15/8243 , A01H5/02 , A01H6/1424 , C12N9/0071 , C12N15/825
摘要： Disclosed are: a method for producing a chrysanthemum plant having delphinidin-containing petals using a transcriptional regulatory region for a chrysanthemum-derived flavanone 3-hydroxylase (F3H) gene; and a chrysanthemum plant, a progeny or a vegetative proliferation product of the plant, or a part or a tissue of the plant, the progeny or the vegetative proliferation product, and particularly a petal or a cut flower of the plant. In the method for producing a chrysanthemum plant having delphinidin-containing petals, a flavonoid 3′,5′-hydroxylase (F3′5′H) is caused to be expressed in a chrysanthemum plant using a transcriptional regulatory region for a chrysanthemum-derived flavanone 3-hydroxylase (F3H) gene.
摘要翻译：公开了一种使用菊花衍生的黄烷酮3-羟化酶（F3H）基因的转录调节区域产生具有花翠素的花瓣的菊花植物的方法。菊花植物，植物的后代或营养增殖产物，植物的一部分或组织，子代或营养增殖产物，特别是植物的花瓣或切花。在具有含花翠素的花瓣的菊花植物的制造方法中，使用菊花衍生的黄烷酮的转录调节区域在菊花植物中表达黄酮3'，5'-羟化酶（F3'5'H） 3-羟化酶（F3H）基因。

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