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1. 发明授权

US09302908B2 Systems and process for forming carbon nanotube sensors 有权
标题翻译：用于形成碳纳米管传感器的系统和工艺
公开(公告)号：US09302908B2
公开(公告)日：2016-04-05
申请号：US12970997
申请日：2010-12-17
申请人： Makarand Paranjape , Jianyun Zhou
发明人： Makarand Paranjape , Jianyun Zhou
IPC分类号： H01L21/66 , B82Y15/00 , B82Y10/00 , G01N27/414 , H01L51/00 , H01L51/05 , B82Y40/00
CPC分类号： H01L51/0048 , B82Y10/00 , B82Y15/00 , B82Y40/00 , G01N27/4145 , H01L51/055 , H01L51/0558
摘要： A process for forming a functionalized sensor for sensing a molecule of interest includes providing at least one single or multi-wall carbon nanotube having a first and a second electrode in contact therewith on a substrate; providing a third electrode including a decorating material on the substrate a predetermined distance from the at least one single or multi-wall carbon nanotube having a first and a second electrode in contact therewith, wherein the decorating material has a bonding affinity for a bioreceptors that react with the molecule of interest; and applying a voltage to the third electrode, causing the decorating material to form nanoparticles of the decorating material on the at least one single or multi-wall carbon nanotube.
摘要翻译：用于形成用于感测感兴趣分子的功能化传感器的方法包括提供至少一个单壁或多壁碳纳米管，其具有与衬底接触的第一和第二电极; 在与所述至少一个具有与其接触的第一和第二电极的所述至少一个单壁或多壁碳纳米管的预定距离的基底上提供包括装饰材料的第三电极，其中所述装饰材料对生物感受器具有结合亲和力，与感兴趣的分子; 以及向所述第三电极施加电压，使所述装饰材料在所述至少一个单壁或多壁碳纳米管上形成所述装饰材料的纳米颗粒。

2. 发明申请

US20120153262A1 Systems and process for forming carbon nanotube sensors 有权
标题翻译：用于形成碳纳米管传感器的系统和工艺
公开(公告)号：US20120153262A1
公开(公告)日：2012-06-21
申请号：US12970997
申请日：2010-12-17
申请人： Makarand Paranjape , Jianyun Zhou
发明人： Makarand Paranjape , Jianyun Zhou
IPC分类号： H01L29/775 , H01L21/335 , B82Y15/00 , B82Y40/00 , B82Y99/00
CPC分类号： H01L51/0048 , B82Y10/00 , B82Y15/00 , B82Y40/00 , G01N27/4145 , H01L51/055 , H01L51/0558
摘要： A process for forming a functionalized sensor for sensing a molecule of interest includes providing at least one single or multi-wall carbon nanotube having a first and a second electrode in contact therewith on a substrate; providing a third electrode including a decorating material on the substrate a predetermined distance from the at least one single or multi-wall carbon nanotube having a first and a second electrode in contact therewith, wherein the decorating material has a bonding affinity for a bioreceptors that react with the molecule of interest; and applying a voltage to the third electrode, causing the decorating material to form nanoparticles of the decorating material on the at least one single or multi-wall carbon nanotube.
摘要翻译：用于形成用于感测感兴趣分子的功能化传感器的方法包括提供至少一个单壁或多壁碳纳米管，其具有与衬底接触的第一和第二电极; 在与所述至少一个具有与其接触的第一和第二电极的所述至少一个单壁或多壁碳纳米管的预定距离的基底上提供包括装饰材料的第三电极，其中所述装饰材料对生物感受器具有结合亲和力，与感兴趣的分子; 以及向所述第三电极施加电压，使所述装饰材料在所述至少一个单壁或多壁碳纳米管上形成所述装饰材料的纳米颗粒。

3. 发明授权

US08138749B1 Optical imaging and patterning based on a magnetically controlled ferrofluid 有权
标题翻译：基于磁控铁磁流体的光学成像和图案化
公开(公告)号：US08138749B1
公开(公告)日：2012-03-20
申请号：US12237325
申请日：2008-09-24
申请人： Makarand Paranjape , Vincent P. Spinella-Mamo
发明人： Makarand Paranjape , Vincent P. Spinella-Mamo
IPC分类号： G01B7/14
CPC分类号： G02B26/004 , G03F7/70291 , H01F1/447
摘要： Methods, systems, and apparatus for optical imaging and patterning based on a magnetically controlled ferrofluid are described. One such system includes a substrate and an active region including multiple magnetic field generators. The active region is positioned adjacent to the substrate. The system includes a ferrofluid positioned on the substrate adjacent the active region within a range of a magnetic field of the multiple magnetic field generators. The ferrofluid is distributed across multiple ferrofluid regions. Each magnetic field generator is aligned with a corresponding ferrofluid region.
摘要翻译：描述了基于磁控铁磁流体的光学成像和图案化的方法，系统和装置。一种这样的系统包括基板和包括多个磁场发生器的有源区域。有源区位于邻近衬底的位置。该系统包括在多个磁场发生器的磁场的范围内与邻近有源区域的基板上的铁磁流体。铁磁流体分布在多个铁磁流体区域。每个磁场发生器与对应的铁磁流体区域对准。

4. 发明授权

US07931592B2 Systems and methods for monitoring health and delivering drugs transdermally 有权
标题翻译：监测健康和经皮递送药物的系统和方法
公开(公告)号：US07931592B2
公开(公告)日：2011-04-26
申请号：US11090156
申请日：2005-03-28
申请人： John F. Currie , Makarand Paranjape , Carl C. Peck , Robert C. White , Thomas W. Schneider
发明人： John F. Currie , Makarand Paranjape , Carl C. Peck , Robert C. White , Thomas W. Schneider
IPC分类号： A61B5/00
CPC分类号： A61B5/150007 , A61B5/0059 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/6833 , A61B2562/12 , A61M5/1723
摘要： The present invention pertains to a system and method for transdermal sampling, comprising: at least one sampler for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject; at least one detector system for identifying and quantifying said at least one analyte; and at least one logic module for (i) receiving and storing input data from said at least one detector, (ii) relating the input data to other data obtained from the subject, (iii) displaying output information, (iv) transmitting the output information to another system, and (v) controlling the operation of said at least one sampler and at least one detector.
摘要翻译：本发明涉及一种用于透皮采样的系统和方法，包括：至少一个采样器，用于从受试者皮肤透皮获取和转移至少一种分析物; 至少一个用于识别和定量所述至少一种分析物的检测器系统; 以及至少一个逻辑模块，用于（i）从所述至少一个检测器接收和存储输入数据，（ii）将输入数据与从对象获得的其他数据相关联，（iii）显示输出信息，（iv）信息到另一系统，以及（v）控制所述至少一个取样器和至少一个检测器的操作。

5. 发明申请

US20050182307A1 Systems and methods for monitoring health and delivering drugs transdermally 有权
公开(公告)号：US20050182307A1
公开(公告)日：2005-08-18
申请号：US11090156
申请日：2005-03-28
申请人： John Currie , Makarand Paranjape , Carl Peck , Robert White , Thomas Schneider
发明人： John Currie , Makarand Paranjape , Carl Peck , Robert White , Thomas Schneider
IPC分类号： G01N33/48 , A61B5/00 , G01N1/10 , G01N33/53 , G01N37/00
CPC分类号： A61B5/150007 , A61B5/0059 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/6833 , A61B2562/12 , A61M5/1723
摘要： The present invention pertains to a system and method for transdermal sampling, comprising: at least one sampler for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject; at least one detector system for identifying and quantifying said at least one analyte; and at least one logic module for (i) receiving and storing input data from said at least one detector, (ii) relating the input data to other data obtained from the subject, (iii) displaying output information, (iv) transmitting the output information to another system, and (v) controlling the operation of said at least one sampler and at least one detector.

6. 发明申请

US20130289374A1 Electrochemical Transdermal Glucose Measurement System Including Microheaters and Process For Forming 审中-公开
标题翻译：电化学透皮葡萄糖测量系统，包括微型加热器和成型工艺
公开(公告)号：US20130289374A1
公开(公告)日：2013-10-31
申请号：US13459392
申请日：2012-04-30
申请人： Makarand Paranjape , Arend Jasper Nijdam , Yogesh Ekanath Kashte
发明人： Makarand Paranjape , Arend Jasper Nijdam , Yogesh Ekanath Kashte
IPC分类号： A61B5/1477 , C25D5/02
CPC分类号： C25D13/12 , A61B5/1451 , A61B5/14532 , A61B5/1477 , A61B5/1486 , A61B18/082 , A61B2018/0047 , A61B2018/00577
摘要： A device contains individually controllable sites for electrochemically monitoring an analyte in interstitial fluid of a user. The sites include a conductive pattern attached at a first and second ends thereof to electrode material in a closed-circuit configuration for receiving a first predetermined voltage applied thereto in order to thermally ablate a stratum corneum of a user's skin to access the interstitial fluid and form an open-circuit configuration including first and second portions of the electrode material that are electrically isolated from each other; a sensing area deposited on at least one of the first and second portions of the electrode material; and a measuring component for receiving individual measurement data from the sensing area in response to a second predetermined voltage applied to the open circuit configuration. The individual measurement data is indicative of an amount of the analyte in the interstitial fluid.
摘要翻译：装置包含用于电化学监测使用者间质液中的分析物的单独可控的部位。这些部位包括在其第一端和第二端处以闭合电路结构连接到电极材料的导电图案，用于接收施加到其上的第一预定电压，以便热消除使用者皮肤的角质层以接近间质液并形成包括彼此电隔离的电极材料的第一和第二部分的开路结构; 沉积在所述电极材料的所述第一和第二部分中的至少一个上的感测区域; 以及测量部件，用于响应于施加到开路结构的第二预定电压，从感测区域接收各个测量数据。各个测量数据表示组织液中分析物的量。

7. 发明申请

US20090308742A1 Flexible Apparatus and Method for Monitoring and Delivery 有权
标题翻译：灵活的装置和监测和交付方法
公开(公告)号：US20090308742A1
公开(公告)日：2009-12-17
申请号：US12096769
申请日：2006-06-14
申请人： Makarand Paranjape
发明人： Makarand Paranjape
IPC分类号： C12M1/40 , C25B11/00
CPC分类号： A61B5/1486 , A61B5/0537 , A61B5/145 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/14865 , A61B5/4547 , Y02A50/53 , Y02A50/58
摘要： The present invention generally relates to a system and method that co-locates in a small flexible, configurable system and multi-level substrate sampling, rapid analysis, bio-sample storage and delivery functions to be performed on living tissues or matter obtained from living organisms. The types of the sampling may include chemical, biochemical, biological, thermal, mechanical, electrical, magnetic and optical sampling. In general, the analysis performed at the point of sampling measures the sample taken and records its value. The bio-sample storage function encapsulates a small sample of analyte and preserves it for subsequent examination or analysis, either on the organism by the system or at a remote location by an independent analysis system. Once stored, the sample can provide a record of a biological state at the precise time of sampling. The delivery at the point of sampling can include chemical, biochemical, thermal, mechanical, electrical, magnetic and optical stimuli.
摘要翻译：本发明一般涉及一种系统和方法，其共同定位在活体组织或从活生物获得的物质上进行的小的灵活，可配置的系统和多层底物取样，快速分析，生物样品储存和递送功能。采样的类型可能包括化学，生化，生物，热，机械，电，磁和光取样。一般来说，在采样点进行的分析测量取样并记录其值。生物样品储存功能封装了一小部分分析物，并保留在随后的检查或分析中，无论是在系统的生物体上还是在独立分析系统的远程位置。一旦存储，样品可以在精确的采样时间提供生物状态的记录。采样点的传送可能包括化学，生化，热，机械，电，磁和光学刺激。

8. 发明申请

US20140121485A2 Electrochemical Transdermal Glucose Measurement System Including Microheaters and Process For Forming 审中-公开
标题翻译：电化学透皮葡萄糖测量系统，包括微型加热器和成型工艺
公开(公告)号：US20140121485A2
公开(公告)日：2014-05-01
申请号：US13459392
申请日：2012-04-30
申请人： Makarand Paranjape , Arend Jasper Nijdam , Yogesh Ekanath Kashte
发明人： Makarand Paranjape , Arend Jasper Nijdam , Yogesh Ekanath Kashte
IPC分类号： A61B5/1477 , C25D5/02
CPC分类号： C25D13/12 , A61B5/1451 , A61B5/14532 , A61B5/1477 , A61B5/1486 , A61B18/082 , A61B2018/0047 , A61B2018/00577
摘要： A device contains individually controllable sites for electrochemically monitoring an analyte in interstitial fluid of a user. The sites include a conductive pattern attached at a first and second ends thereof to electrode material in a closed-circuit configuration for receiving a first predetermined voltage applied thereto in order to thermally ablate a stratum corneum of a user's skin to access the interstitial fluid and form an open-circuit configuration including first and second portions of the electrode material that are electrically isolated from each other; a sensing area deposited on at least one of the first and second portions of the electrode material; and a measuring component for receiving individual measurement data from the sensing area in response to a second predetermined voltage applied to the open circuit configuration. The individual measurement data is indicative of an amount of the analyte in the interstitial fluid.
摘要翻译：装置包含用于电化学监测使用者间质液中的分析物的单独可控的部位。这些部位包括在其第一端和第二端处以闭合电路结构连接到电极材料的导电图案，用于接收施加到其上的第一预定电压，以便热消除使用者皮肤的角质层以接近间质液并形成包括彼此电隔离的电极材料的第一和第二部分的开路结构; 沉积在电极材料的第一和第二部分中的至少一个上的感测区域; 以及测量部件，用于响应于施加到开路结构的第二预定电压，从感测区域接收各个测量数据。各个测量数据表示组织液中分析物的量。

9. 发明申请

US20130105824A1 Method and System for Generating a Photo-Response from MoS2 Schottky Junctions 有权
标题翻译：用于从MoS2肖特基接头产生光响应的方法和系统
公开(公告)号：US20130105824A1
公开(公告)日：2013-05-02
申请号：US13661979
申请日：2012-10-26
申请人： Makarand Paranjape , Paola Barbara , Amy Liu , Marcio Fontana
发明人： Makarand Paranjape , Paola Barbara , Amy Liu , Marcio Fontana
IPC分类号： H01L33/02 , H01L31/032
CPC分类号： H01L33/005 , H01L31/032 , H01L31/035209 , H01L31/07 , H01L31/1013 , H01L31/18 , H01L33/0041 , H01L33/06 , H01L33/28 , H01L33/40 , Y02E10/50
摘要： Devices incorporating a single to a few-layer MoS2 channels in combination with optimized substrate, dielectric, contact and electrode materials and configurations thereof, exhibit light emission, photoelectric effect, and superconductivity, respectively.
摘要翻译：结合单层至几层MoS2通道的设备与优化的基板，电介质，接触和电极材料及其构造相结合，分别显示出发光，光电效应和超导性。

10. 发明授权

US08568315B2 Systems and methods for monitoring health and delivering drugs transdermally 有权
公开(公告)号：US08568315B2
公开(公告)日：2013-10-29
申请号：US13085775
申请日：2011-04-13
申请人： John F. Currie , Makarand Paranjape , Carl C. Peck , Robert White , Thomas W. Schneider
发明人： John F. Currie , Makarand Paranjape , Carl C. Peck , Robert White , Thomas W. Schneider
IPC分类号： A61B5/00
CPC分类号： A61B5/150007 , A61B5/0059 , A61B5/14514 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/6833 , A61B2562/12 , A61M5/1723
摘要： The present invention pertains to a system and method for transdermal sampling, comprising: at least one sampler for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject; at least one detector system for identifying and quantifying said at least one analyte; and at least one logic module for (i) receiving and storing input data from said at least one detector, (ii) relating the input data to other data obtained from the subject, (iii) displaying output information, (iv) transmitting the output information to another system, and (v) controlling the operation of said at least one sampler and at least one detector.

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