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    • 1. 发明授权
    • Illumination device, in particular for microscopes
    • 照明装置,特别是显微镜
    • US08125709B2
    • 2012-02-28
    • US11887462
    • 2006-06-22
    • Lutz HoeringAndreas NolteMichael BrehmMario Sondermann
    • Lutz HoeringAndreas NolteMichael BrehmMario Sondermann
    • G02B21/06
    • G02B21/06
    • The present invention is directed to a controllable microscope illumination within a microscope system by which all essential contrasting methods in microscopy can be realized. The illumination device according to the invention comprises a plurality of individual light sources which can be regulated with respect to brightness, wherein these individual light sources are formed as unit cells and form a luminous surface by a periodic arrangement. In an advantageous arrangement, imaging optics are associated with each individual light source in order to magnify the image of the source surface of the individual light source so that the images of the source surfaces of adjacent individual light sources touch. Illumination variants for all of the essential contrasting methods in microscopy can be generated by way of the proposed solution. The proposed LED illumination is electronically switchable, can be regulated with respect to brightness, supplies all colors, is long-lasting and economical. LEDs have a long life and are very robust and insensitive to vibrations. The spatial light distribution and the color temperature are adjustable.
    • 本发明涉及在显微镜系统内的可控显微照明,通过该照明可以实现显微镜中的所有必要的对比方法。 根据本发明的照明装置包括可以相对于亮度调节的多个单独的光源,其中这些单个光源被形成为单元电池并且通过周期性布置形成发光表面。 在有利的布置中,成像光学器件与每个单独的光源相关联,以便放大单个光源的源表面的图像,使得相邻单独光源的源表面的图像接触。 可以通过提出的解决方案来产生显微镜中所有基本对比方法的照明变体。 提出的LED照明是电子可切换的,可以根据亮度进行调节,供应所有颜色,是持久和经济的。 LED寿命长,非常坚固,对振动不敏感。 空间光分布和色温可调。
    • 2. 发明申请
    • METHOD AND DEVICE FOR THE IMMERSION AND CLEANING OF THE FRONT LENS OF MICROSCOPE OBJECTIVES
    • 用于显微镜目标的前视镜的浸没和清洁的方法和装置
    • US20070047093A1
    • 2007-03-01
    • US11467231
    • 2006-08-25
    • Lutz HoeringAndreas Nolte
    • Lutz HoeringAndreas Nolte
    • G02B21/02
    • G02B27/0006G02B21/02
    • A method and a device are provided for the immersion and for the cleaning of the front lens of microscope objectives in fully automatic microscope systems, in particular inverted microscopes, for the examination of biological and/or chemical samples by which, besides an automatic immersion process, an automatic cleaning of the front lens of the microscope objective is achieved at the same time at the conclusion of the immersion process. In a method in which water is preferably used as immersion liquid, the immersion liquid is provided at the same time as a cleaning liquid for the automatic cleaning of a front lens of a microscope objective at the conclusion of the immersion process. The device according to the invention for implementing the method comprises a receiving vessel which can be placed on the front lens of the microscope objective. Openings are provided in the receiving vessel and are connected to a tube system for supplying fresh immersion and cleaning liquid from a reservoir vessel and for discharging the soiled liquid into a receiving vessel.
    • 提供了一种方法和装置,用于在全自动显微镜系统(特别是倒置显微镜)中用于浸没和清洁显微镜物镜的前透镜,用于检查生物和/或化学样品,除了自动浸没过程 在浸入过程结束的同时,实现了显微镜物镜的前镜的自动清洁。 在优选使用水作为浸渍液体的方法中,浸渍液同时设置为在浸渍处理结束时自动清洁显微镜物镜的前透镜的清洗液。 根据本发明的用于实现该方法的装置包括可放置在显微镜物镜的前透镜上的接收容器。 开口设置在接收容器中并且连接到管系统,用于从储存容器提供新鲜的浸没和清洁液体,并将污染的液体排放到接收容器中。
    • 3. 发明申请
    • AUTOMATIC MICROSCOPE AND METHOD FOR TRUE-COLOR IMAGE
    • 自动显微镜和真彩色图像的方法
    • US20070014000A1
    • 2007-01-18
    • US11427260
    • 2006-06-28
    • Andreas NolteLutz Hoering
    • Andreas NolteLutz Hoering
    • G02B21/00
    • G02B21/06G02B21/361G02B21/362
    • The object in an automatic microscope and a method for true-color image reproduction in automatic microscopes is to provide a monitor image which corresponds to the optical impression of an eyepiece image with respect to color and contrast. According to the invention, the spectral distribution of a light source which can be controlled with respect to brightness and/or color temperature is determined upon initial startup, and the intensity of spectral components is associated with control parameters for the light source. Measurements of the spectral distribution of the light source when operating the microscope and of the ratio of the intensity of spectral components to the control parameters which is determined upon initial startup are used for the regulated control of the light source. Further, the spectral distribution of the monitor image is determined upon initial startup, and the measured spectral distributions of the light source and of the monitor image are compared with the spectral distributions of the light source and of the monitor image determined upon initial startup. Spectral deviations determined in the distributions are compensated by adapting the spectral distribution of the monitor image to the spectral distribution of the light source.
    • 自动显微镜中的物体和用于自动显微镜中的真彩色图像再现的方法是提供对应于目镜图像相对于颜色和对比度的光学印象的监视器图像。 根据本发明,可以在初始启动时确定可以控制亮度和/或色温的光源的光谱分布,并且光谱分量的强度与光源的控制参数相关联。 在操作显微镜时光源的光谱分布的测量以及光谱分量的强度与初始启动时确定的控制参数的比率被用于光源的调节控制。 此外,监视图像的光谱分布在初始启动时确定,并且将光源和监视器图像的测量光谱分布与初始启动时确定的光源和监视器图像的光谱分布进行比较。 在分布中确定的光谱偏差通过将监测图像的光谱分布适应于光源的光谱分布来补偿。
    • 5. 发明申请
    • Illuminating Device for Microscopes
    • 显微镜照明装置
    • US20090034248A1
    • 2009-02-05
    • US11922909
    • 2006-06-22
    • Gunter RudolphJochen MullerEva-Maria MenzelBryce Anton MoffatAndreas Nolte
    • Gunter RudolphJochen MullerEva-Maria MenzelBryce Anton MoffatAndreas Nolte
    • C09K11/00
    • G02B21/084F21K9/00F21K9/61F21Y2115/10G02B6/0003G02B21/10G02B21/12H01L25/0753H01L33/50H01L2924/0002H01L2924/00
    • The invention relates to an illuminating device for microscopes, wherein the light source has, in particular, a white light illumination having total daylight spectrum and/or an excitation light source for fluorescent colors. The inventive illuminating device for a microscope consists of surface or spatially arranged light sources, which are connected to a control unit for generating any desired illuminating patterns and illuminating spectrums, and an illuminating optic to image these illuminating patterns on the object to be examined. The light sources consist of LEDs (11) which excite at least one luminescence color (14) which is adapted to the wavelength which is emitted by the LEDs (11). The LEDs (11) are arranged concentrically to the optical axis of the illuminating device, preferably, in or in the vicinity of the aperture diaphragm plane. The microscope illumination enables realization of flexible illumination structures and illumination spectrums for bright field, dark field, fluorescence, inclined and/or annularly-shaped illumination, and also white light illuminations having total daylight spectrum. Due to the advantages of the LEDs (economical, low power consumption, long service life and easy to control), such illumination devices are particularly suitable for use in the field, for example, in archaeology, geology and in protecting the environment.
    • 本发明涉及一种用于显微镜的照明装置,其中光源具有特别是具有总日光光谱的白光照明和/或用于荧光颜色的激发光源。 用于显微镜的本发明的照明装置由表面或空间上布置的光源组成,其连接到用于产生任何期望的照明图案和照明光谱的控制单元,以及照明光学器件,用于将这些照明图案成像在待检查对象上。 光源由LED(11)组成,其激发适于由LED(11)发射的波长的至少一种发光颜色(14)。 LED(11)同心地布置在照明装置的光轴上,优选地在孔径光阑平面内或附近。 显微镜照明使得能够实现用于明场,暗场,荧光,倾斜和/或环形照明的柔性照明结构和照明光谱,以及具有总日光谱的白光照明。 由于LED的优点(经济,低功耗,长使用寿命和易于控制),这种照明装置特别适用于现场,例如考古学,地质学和保护环境。
    • 8. 发明授权
    • Safety system for a laser radiation device
    • 激光辐射装置的安全系统
    • US08004757B2
    • 2011-08-23
    • US11664448
    • 2005-09-14
    • Andreas NolteHubert WahlKlaus Becker
    • Andreas NolteHubert WahlKlaus Becker
    • G02B21/00
    • G02B21/0024G02B21/24
    • A laser radiation-guiding device including: a laser including a control unit; ports for connection of one module each, it being possible that laser radiation may exit at the ports. The device further can include joining part sensors respectively assigned to a port and whose electrical condition depends on whether a predetermined joining part is spaced apart from the respective port by less than a maximum distance in a predetermined orientation relative to the respective port, and an evaluating unit connected to the joining part sensors via a signal link that detects the electrical conditions of the joining part sensors and, depending on the detected conditions, emits a control signal to the control unit of the laser or to a laser radiation-blocking unit, by which emission of eye-damaging laser radiation to the ports of the device can be prevented inhibited.
    • 一种激光辐射引导装置,包括:激光器,包括控制单元; 用于连接每个模块的端口,激光辐射可能在端口处可能离开。 该装置还可以包括分别分配给端口的接合部分传感器,其电气状态取决于预定接合部分是否相对于相应端口以预定取向相对于相应端口间隔小于最大距离,并且评估 单元通过检测接合部件传感器的电气条件的信号链路连接到接合部件传感器,并且根据检测到的条件,将控制信号发送到激光器的控制单元或激光辐射阻断单元,通过 可以防止对装置的端口发出对眼睛有害的激光辐射。