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    • 1. 发明申请
    • Polyvalent vaccine against diseases caused by papilloma viruses, method for the production and the use thereof
    • 针对由乳头瘤病毒引起的疾病的多价疫苗,其生产方法及其用途
    • US20050004054A1
    • 2005-01-06
    • US10485454
    • 2002-07-26
    • Lutz GissmanKai PohlmeyerMartin Muller
    • Lutz GissmanKai PohlmeyerMartin Muller
    • A61K39/12A61K39/295C07K16/08A61K48/00C12N15/86
    • C07K16/084A61K39/12C12N2710/20034
    • A vaccine against disease caused by papilloma viruses is described in certain embodiments, as well as certain vectors, obtainable by the following methods: (a) one or more expression vectors that contain the DNA code for a structural protein of papilloma viruses or a fragment thereof are injected into mammals, whereby in at least some of the expression vectors randomly generated heterologous sequences are inserted into the DNA code (b) serums are obtained from the mammals and these are tested for the presence of antibodies against particles of various papilloma virus types, and (c) using the serums tested, the structural protein gene clones are identified that code for a polyvalent vaccine, and (d) the vaccine is produced from them. Procedures for producing a vaccine is also described, together with its use for vaccination against diseases caused by papilloma viruses.
    • 在某些实施方案中描述了针对由乳头瘤病毒引起的疾病的疫苗,以及可通过以下方法获得的某些载体:(a)含有乳头状瘤病毒或其片段的结构蛋白的DNA编码的一种或多种表达载体 注射到哺乳动物中,由此在至少一些表达载体中随机产生的异源序列插入到DNA代码(b)中,从哺乳动物获得血清,并测试这些血清是否存在针对各种乳头状瘤病毒类型的颗粒的抗体, 和(c)使用测试的血清,鉴定编码多价疫苗的结构蛋白质基因克隆,和(d)从它们产生疫苗。 还描述了生产疫苗的程序,以及其用于针对由乳头瘤病毒引起的疾病的疫苗接种的用途。
    • 3. 发明申请
    • Production and applications for polyvalent vaccines against diseases caused by papilloma viruses
    • 针对乳头瘤病毒引起的疾病的多价疫苗的生产和应用
    • US20050026257A1
    • 2005-02-03
    • US10778936
    • 2004-02-13
    • Lutz GissmannKai PohlmeyerMartin Muller
    • Lutz GissmannKai PohlmeyerMartin Muller
    • A61K39/12A61K39/295C07K16/08C12P21/04C12N15/86
    • C07K16/084A61K39/12C12N2710/20034
    • A vaccine against disease caused by papilloma viruses is described in certain embodiments, as well as certain vectors, obtainable by the following methods: (a) one or more expression vectors that contain the DNA code for a structural protein of papilloma viruses or a fragment thereof are injected into mammals, whereby in at least some of the expression vectors randomly generated heterologous sequences are inserted into the DNA code (b) serums are obtained from the mammals and these are tested for the presence of antibodies against particles of various papilloma virus types, and (c) using the serums tested, the structural protein gene clones are identified that code for a polyvalent vaccine, and (d) the vaccine is produced from them. Procedures for producing a vaccine is also described, together with its use for vaccination against diseases caused by papilloma viruses.
    • 在某些实施方案中描述了针对由乳头瘤病毒引起的疾病的疫苗,以及可通过以下方法获得的某些载体:(a)含有乳头状瘤病毒或其片段的结构蛋白的DNA编码的一种或多种表达载体 注射到哺乳动物中,由此在至少一些表达载体中随机产生的异源序列插入到DNA代码(b)中,从哺乳动物获得血清,并测试这些血清是否存在针对各种乳头状瘤病毒类型的颗粒的抗体, 和(c)使用测试的血清,鉴定编码多价疫苗的结构蛋白质基因克隆,和(d)从它们产生疫苗。 还描述了生产疫苗的程序,以及其用于针对由乳头瘤病毒引起的疾病的疫苗接种的用途。
    • 6. 发明申请
    • SYSTEM AND METHOD FOR MODELING OF TURBO-CHARGED ENGINES AND INDIRECT MEASUREMENT OF TURBINE AND WASTE-GATE FLOW AND TURBINE EFFICIENCY
    • 涡轮增压发动机的建模系统和方法以及涡轮机和废气流量和涡轮机效率的间接测量
    • US20090094009A1
    • 2009-04-09
    • US11867422
    • 2007-10-04
    • Martin Muller
    • Martin Muller
    • G06G7/48
    • G06F17/5009F02D41/0007F02D41/1445F02D41/1447F02D41/145F02D2041/1433G06F17/5095G06F2217/16G06F2217/80Y02T10/144Y02T10/82
    • A real-time system for modeling a turbo-charged engine includes a model configured to estimate various exhaust states such as turbine inlet pressure, turbine outlet pressure, turbine outlet temperature, turbine mass flow rate and waste-gate valve mass flow rate. The model is dependent only on the availability of normal operating values available in a conventionally-configured automotive controller and one or more measured intake side parameters such as ambient pressure, boost pressure, ambient temperature and compressor mass flow rate. The model is constructed to reflect a high-level application of energy conservation between the turbine (generated power) and compressor (absorbed power). A method for the indirect measurement of turbine and waste-gate flow uses turbine inlet and outlet pressure, inlet temperature and engine mass air flow rate measurements. A method for the indirect measurement of turbine efficiency avoids the need for manufacturer's turbine data.
    • 用于对涡轮增压发动机进行建模的实时系统包括被配置为估计各种排气状态的模型,例如涡轮进口压力,涡轮出口压力,涡轮出口温度,涡轮质量流量和废气门阀质量流量。 该模型仅取决于常规配置的汽车控制器中可用的正常工作值的可用性以及一个或多个测量的进气侧参数,例如环境压力,增压压力,环境温度和压缩机质量流量。 该模型被构造为反映在涡轮(发电)和压缩机(吸收功率)之间的节能的高水平应用。 用于间接测量涡轮机和废气门流量的方法使用涡轮机入口和出口压力,入口温度和发动机质量空气流量测量。 用于间接测量涡轮机效率的方法避免了制造商的涡轮数据的需要。
    • 10. 发明申请
    • Electric device with a user guide
    • 带有用户指南的电气设备
    • US20070069915A1
    • 2007-03-29
    • US10579708
    • 2004-11-24
    • Christoph BeckeMartin Muller
    • Christoph BeckeMartin Muller
    • G08B5/00
    • H01H13/84H01H9/182H01H2217/038H01H2239/05H01H2300/022
    • An electric device comprising a plurality of operating elements which can be operated by a user. Said device is associated with a status display device, and it also comprises a control logic unit which is coupled to the operating elements in order to detect user operations and which is adjusted. Furthermore, the electric device has an operational state which corresponds to the user operations which are to be adjusted. In a first state, the control logic unit displaces the status display of each operational element, from which it is able to process a user operation, according to an adjusted operational state, and in a second state, said unit displaces the status display of each operational element, whereby it is not possible to process a user operation, according to an adjusted operational state.
    • 一种电气设备,包括可由用户操作的多个操作元件。 所述设备与状态显示设备相关联,并且还包括耦合到操作元件的控制逻辑单元,以便检测用户操作并调整哪一个。 此外,电气设备具有对应于要调整的用户操作的操作状态。 在第一状态下,控制逻辑单元根据经调整的操作状态移动每个操作元件的状态显示,从而可以处理用户操作,并且在第二状态下,所述单元移位每个操作元件的状态显示 操作元件,由此根据调整的操作状态不可能处理用户操作。