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1. 发明申请

US20090078638A1 Centrifugal filter 有权
标题翻译：离心过滤器
公开(公告)号：US20090078638A1
公开(公告)日：2009-03-26
申请号：US11903577
申请日：2007-09-24
申请人： Louis Bonhomme , John Doyle , Kurt Geenizen , George Gagne , Sean Devin , Gerard Lombard , Vincent Smith
发明人： Louis Bonhomme , John Doyle , Kurt Geenizen , George Gagne , Sean Devin , Gerard Lombard , Vincent Smith
IPC分类号： B01D36/00 , B01D63/00 , B01D29/00
CPC分类号： B01D63/16 , B01D61/145 , B01D61/18 , B01D63/08 , B01D2313/08 , B01L3/502 , B01L3/5021 , B01L3/5635 , B01L2300/0681
摘要： Filtration device suited for concentration of liquid samples, particularly biomolecules, and a method of concentrating, desalting, purifying and/or fractionating liquid samples. In certain embodiments the device includes a housing having a sample reservoir, and two substantially vertically oriented and spaced apart membranes disposed in the housing. An underdrain is associated with each membrane such that fluid passing through each membrane flows through a respective underdrain into a filtrate collection chamber. The fluid that does not pass through the membrane is collected in the retentate collection chamber, and can be recovered such as by a reverse spinning step, achieving recoveries greater than about 90%. The substantially vertical orientation of the membranes increases the available membrane area by at least 2.7 times the area available in a conventional filter device. The two-panel configuration also maintains more available membrane area in use during the last stages of filtration than a one-panel configuration.
摘要翻译：适用于浓缩液体样品，特别是生物分子的过滤装置，以及浓缩，脱盐，纯化和/或分馏液体样品的方法。在某些实施方案中，该装置包括具有样品储存器的壳体和设置在壳体中的两个基本垂直定向和间隔开的膜。与每个膜相关联的下划线，使得通过每个膜的流体通过相应的下划线流入滤液收集室。不通过膜的流体被收集在滞留物收集室中，并且可以通过反转纺步骤回收，实现大于约90％的回收率。膜的基本垂直取向将可用的膜面积增加了传统过滤装置中可用面积的至少2.7倍。两面板配置在过滤的最后阶段比在单面板配置中还维持使用更多的可用膜面积。

2. 发明授权

US08357296B2 Centrifugal filter 有权
公开(公告)号：US08357296B2
公开(公告)日：2013-01-22
申请号：US11903577
申请日：2007-09-24
申请人： Louis Bonhomme , John Doyle , Kurt Greenizen , George Gagne , Sean Devin , Gerard Lombard , Vincent Smith , Mark Kavonian
发明人： Louis Bonhomme , John Doyle , Kurt Greenizen , George Gagne , Sean Devin , Gerard Lombard , Vincent Smith , Mark Kavonian
IPC分类号： B01D63/08 , B01D25/22 , B01D21/26
CPC分类号： B01D63/16 , B01D61/145 , B01D61/18 , B01D63/08 , B01D2313/08 , B01L3/502 , B01L3/5021 , B01L3/5635 , B01L2300/0681
摘要： Filtration device suited for concentration of liquid samples, particularly biomolecules, and a method of concentrating, desalting, purifying and/or fractionating liquid samples. In certain embodiments the device includes a housing having a sample reservoir, and two substantially vertically oriented and spaced apart membranes disposed in the housing. An underdrain is associated with each membrane such that fluid passing through each membrane flows through a respective underdrain into a filtrate collection chamber. The fluid that does not pass through the membrane is collected in the retentate collection chamber, and can be recovered such as by a reverse spinning step, achieving recoveries greater than about 90%. The substantially vertical orientation of the membranes increases the available membrane area by at least 2.7 times the area available in a conventional filter device. The two-panel configuration also maintains more available membrane area in use during the last stages of filtration than a one-panel configuration.

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