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1. 发明申请

US20120265198A1 RENAL NERVE DETECTION AND ABLATION APPARATUS AND METHOD 审中-公开
标题翻译：肾脏神经检测和消融装置及方法
公开(公告)号：US20120265198A1
公开(公告)日：2012-10-18
申请号：US13299932
申请日：2011-11-18
申请人： Loren M. Crow , Mark L. Jenson , Scott Smith
发明人： Loren M. Crow , Mark L. Jenson , Scott Smith
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/0016 , A61B2018/00267 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00791 , A61B2018/00875 , A61B2018/124 , A61N1/36007 , A61N7/022
摘要： Stimulation energy is delivered to one or more renal artery sites in accordance with a predetermined energy delivery protocol. The stimulation energy is sufficient to elicit a physiologic response from the patient but insufficient to ablate renal nerves. Target renal artery sites that elicit a physiologic response are identified, and renal nerve tissue at or proximate the target sites is ablated.
摘要翻译：根据预定的能量递送方案，将刺激能量递送至一个或多个肾动脉部位。刺激能量足以引起患者的生理反应，但不足以消融肾神经。确定引起生理反应的目标肾动脉部位，消除靶点位置或其附近的肾神经组织。

2. 发明授权

US09220561B2 Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury 有权
标题翻译：导管相容的大电极导管用于肾神经消融，减少动脉损伤
公开(公告)号：US09220561B2
公开(公告)日：2015-12-29
申请号：US13353948
申请日：2012-01-19
申请人： Loren M. Crow , Mark L. Jenson
发明人： Loren M. Crow , Mark L. Jenson
IPC分类号： A61B18/14 , A61B19/00 , A61B17/00 , A61B18/00
CPC分类号： A61B18/1492 , A61B90/39 , A61B2017/00473 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2090/0808
摘要： A first catheter is dimensioned for deployment within a renal artery. A second catheter has a shaft with an outer diameter smaller than an inner diameter of the first catheter's open lumen. A gap is formed between the shaft and the first catheter when the second catheter is situated within the first catheter. The gap facilitates transport of a fluid, such as imaging contrast media, along the first catheter. An electrode arrangement at the distal end of the shaft is configured to deliver ablative energy to perivascular renal nerves, and has an outer diameter about the same size as the inner diameter of the first catheter such that a fit therebetween substantially blocks fluid flow within the gap yet provides for relative movement between the electrode arrangement and the luminal wall. A conductor extends between the proximal and distal ends of the shaft and is coupled to electrode arrangement.
摘要翻译：第一个导管的尺寸用于部署在肾动脉内。第二导管具有外径小于第一导管开口腔内径的轴。当第二导管位于第一导管内时，在轴和第一导管之间形成间隙。该间隙便于沿着第一导管输送诸如成像造影剂的流体。在轴的远端处的电极布置被配置为将消融能量递送至血管周围肾神经，并且具有与第一导管的内径大致相同尺寸的外径，使得其间的配合基本上阻挡在间隙内的流体流动而是提供电极装置和腔壁之间的相对运动。导体在轴的近端和远端之间延伸并耦合到电极装置。

3. 发明申请

US20120265066A1 GUIDE-COMPATIBLE LARGE-ELECTRODE CATHETER FOR RENAL NERVE ABLATION WITH REDUCED ARTERIAL INJURY 有权
标题翻译：指导兼容的大电极导管，用于神经退化，减少肢体损伤
公开(公告)号：US20120265066A1
公开(公告)日：2012-10-18
申请号：US13353948
申请日：2012-01-19
申请人： Loren M. Crow , Mark L. Jenson
发明人： Loren M. Crow , Mark L. Jenson
IPC分类号： A61B6/00 , A61B18/14
CPC分类号： A61B18/1492 , A61B90/39 , A61B2017/00473 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2090/0808
摘要： A first catheter is dimensioned for deployment within a renal artery. A second catheter has a shaft with an outer diameter smaller than an inner diameter of the first catheter's open lumen. A gap is formed between the shaft and the first catheter when the second catheter is situated within the first catheter. The gap facilitates transport of a fluid, such as imaging contrast media, along the first catheter. An electrode arrangement at the distal end of the shaft is configured to deliver ablative energy to perivascular renal nerves, and has an outer diameter about the same size as the inner diameter of the first catheter such that a fit therebetween substantially blocks fluid flow within the gap yet provides for relative movement between the electrode arrangement and the luminal wall. A conductor extends between the proximal and distal ends of the shaft and is coupled to electrode arrangement.
摘要翻译：第一个导管的尺寸用于部署在肾动脉内。第二导管具有外径小于第一导管开口腔内径的轴。当第二导管位于第一导管内时，在轴和第一导管之间形成间隙。该间隙便于沿着第一导管输送诸如成像造影剂的流体。在轴的远端处的电极布置被配置为将消融能量递送至血管周围肾神经，并且具有与第一导管的内径大致相同尺寸的外径，使得其间的配合基本上阻挡在间隙内的流体流动而是提供电极装置和腔壁之间的相对运动。导体在轴的近端和远端之间延伸并耦合到电极装置。

4. 发明授权

US08945047B2 Traction balloon 有权
公开(公告)号：US08945047B2
公开(公告)日：2015-02-03
申请号：US12505974
申请日：2009-07-20
申请人： Steven A. McAuley , Karen M. Cheves , Loren M. Crow , Gregory S. Kelley , Herbert R. Radisch, Jr. , Ricardo David Roman , Show-Mean Wu
发明人： Steven A. McAuley , Karen M. Cheves , Loren M. Crow , Gregory S. Kelley , Herbert R. Radisch, Jr. , Ricardo David Roman , Show-Mean Wu
IPC分类号： A61M29/00 , A61M25/10
CPC分类号： A61M25/10 , A61M2025/1086
摘要： Balloon catheters and methods of making and using the same. A balloon catheter may include a catheter shaft and a balloon coupled thereto. A traction member may be coupled to the balloon catheter adjacent the balloon and may extend along a portion or all of the length of the balloon. The traction member can improve traction between the balloon and a target site.

5. 发明授权

US07291158B2 Cutting balloon catheter having a segmented blade 有权
标题翻译：具有分段叶片的切割气囊导管
公开(公告)号：US07291158B2
公开(公告)日：2007-11-06
申请号：US10987011
申请日：2004-11-12
申请人： Loren M. Crow , Steven W. Bence
发明人： Loren M. Crow , Steven W. Bence
IPC分类号： A61B17/22 , A61B17/32 , A61M29/00
CPC分类号： A61B17/320725 , A61B2017/22061 , A61M25/1002 , A61M2025/1086
摘要： A cutting balloon catheter and method of making and using the same. The cutting balloon catheter may include a catheter shaft having a balloon coupled thereto. One or more cutting members or blades may be coupled to the balloon. The cutting members may include two or more sections that are connected via a fracturable or yielding bridge section that increases flexibility when passing through or being utilized in tortuous anatomy.
摘要翻译：切割气囊导管及其制造和使用方法。切割气囊导管可以包括具有与其联接的气囊的导管轴。一个或多个切割构件或叶片可以联接到气囊。切割构件可以包括两个或更多个部分，所述两个或更多个部分经由可折叠或屈服的桥接部分连接，当通过或被用于曲折的解剖结构时，该部分增加了灵活性。

6. 发明授权

US07736375B2 Balloon catheter with controller depth incising blade 有权
标题翻译：气囊导管与控制器深度切割刀片
公开(公告)号：US07736375B2
公开(公告)日：2010-06-15
申请号：US10998455
申请日：2004-11-29
申请人： Loren M. Crow
发明人： Loren M. Crow
IPC分类号： A61B17/32
CPC分类号： A61B17/3207 , A61B17/320725 , A61B2017/00292 , A61B2017/22038 , A61B2017/22051 , A61B2017/22061
摘要： A device for incising tissue to a pre-selected incision depth within a body conduit of a patient includes an elongated balloon catheter and at least one elongated straight blade that is mounted on the balloon. To control the incision depth, each blade has a blunt section formed with a non-incising surface and a cutting edge positioned distally to the blunt section. A proximal portion of the blade is attached to a proximal balloon section, and in operation, the balloon/blade combination is advanced into the body conduit and positioned distal to the target tissue/stenosis. The balloon is then inflated. With this inflation, the blade is inclined relative to the axis of the catheter with an increasing distance between the blade and the axis in a distal direction. The device is then withdrawn, proximally, to incise the tissue/stenosis.
摘要翻译：用于将组织切割成患者的体导管内的预先选择的切口深度的装置包括细长的气囊导管和安装在气囊上的至少一个细长的直叶片。为了控制切口深度，每个刀片具有钝化部分，其形成有非切削表面和位于钝部部分的远侧的切削刃。叶片的近端部分附接到近端球囊部分，并且在操作中，气囊/叶片组合进入体导管并定位在靶组织/狭窄处的远侧。然后气球膨胀。随着这种膨胀，叶片相对于导管的轴线倾斜，并且叶片和轴线在远端方向上的距离增加。然后将装置向近端取出以切开组织/狭窄。

7. 发明申请

US20090281490A1 Traction Balloon 有权
标题翻译：牵引气球
公开(公告)号：US20090281490A1
公开(公告)日：2009-11-12
申请号：US12505974
申请日：2009-07-20
申请人： Steven A. McAuley , Karen M. Cheves , Loren M. Crow , Gregory S. Kelley , Herbert R. Radisch, JR. , Ricardo David Roman , Show-Mean Wu
发明人： Steven A. McAuley , Karen M. Cheves , Loren M. Crow , Gregory S. Kelley , Herbert R. Radisch, JR. , Ricardo David Roman , Show-Mean Wu
IPC分类号： A61M25/10
CPC分类号： A61M25/10 , A61M2025/1086
摘要： Balloon catheters and methods of making and using the same. A balloon catheter may include a catheter shaft and a balloon coupled thereto. A traction member may be coupled to the balloon catheter adjacent the balloon and may extend along a portion or all of the length of the balloon. The traction member can improve traction between the balloon and a target site.
摘要翻译：气球导管及其使用方法。气囊导管可以包括导管轴和与其联接的气囊。牵引构件可以与球囊邻近的球囊导管联接，并且可以沿气囊的一部分或全部长度延伸。牵引构件可以改善气球和目标位置之间的牵引力。

8. 发明授权

US07566319B2 Traction balloon 有权
标题翻译：牵引气球
公开(公告)号：US07566319B2
公开(公告)日：2009-07-28
申请号：US10828572
申请日：2004-04-21
申请人： Steven A. McAuley , Karen M. Cheves , Loren M. Crow , Gregory S. Kelley , Herbert R. Radisch, Jr. , Ricardo David Roman , Show-Mean Wu
发明人： Steven A. McAuley , Karen M. Cheves , Loren M. Crow , Gregory S. Kelley , Herbert R. Radisch, Jr. , Ricardo David Roman , Show-Mean Wu
IPC分类号： A61M29/00
CPC分类号： A61M25/10 , A61M2025/1086
摘要： Balloon catheters and methods of making and using the same. A balloon catheter may include a catheter shaft and a balloon coupled thereto. A traction member may be coupled to the balloon catheter adjacent the balloon and may extend along a portion or all of the length of the balloon. The traction member can improve traction between the balloon and a target site.
摘要翻译：气球导管及其使用方法。气囊导管可以包括导管轴和与其联接的气囊。牵引构件可以与球囊邻近的球囊导管联接，并且可以沿气囊的一部分或全部长度延伸。牵引构件可以改善气球和目标位置之间的牵引力。

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