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1. 发明申请

US20060111680A1 Autoclaveable small-volume dropper bottle 有权
标题翻译：高压灭菌小容量滴瓶
公开(公告)号：US20060111680A1
公开(公告)日：2006-05-25
申请号：US10997266
申请日：2004-11-23
申请人： Lon Spada , Paul Butorac , Scott Gerondale
发明人： Lon Spada , Paul Butorac , Scott Gerondale
IPC分类号： A61M35/00 , B65D47/18
CPC分类号： A61F9/0008 , B65D1/32 , B65D47/18
摘要： A terminally sterilizable container includes a polypropylene bottle having a body with a manually squeezable sidewall and a thickness preventing water loss. The bottle body includes shoulders for providing autoclave produced pressure distribution and deformation resistance along with an elongated tips outfitted to a neck of the body and having a lumen therethrough with a drop dispensing orifice. A cap enclosed the elongated tip and includes enclosed with a nub for sealing the orifice to prevent autoclave produced pressure leaks.
摘要翻译：末端可灭菌的容器包括具有手动可挤压侧壁的主体和防止水分损失的厚度的聚丙烯瓶。瓶体包括用于提供高压釜产生的压力分布和变形阻力的肩部以及装配到主体的颈部并且具有通过其的腔的液滴分配孔的细长尖端。盖子包住细长的尖端，并且包括用小孔封闭以密封孔口，以防止高压釜产生的压力泄漏。

2. 发明申请

US20060032873A1 Container system 审中-公开
标题翻译：集装箱系统
公开(公告)号：US20060032873A1
公开(公告)日：2006-02-16
申请号：US10916067
申请日：2004-08-11
申请人： Scott Gerondale , Lon Spada , Paul Butorac
发明人： Scott Gerondale , Lon Spada , Paul Butorac
IPC分类号： B65D25/40
CPC分类号： B65D1/0246 , B65D47/18
摘要： A container system includes a squeeze bottle of a specific volume having a neck with an open end and a medicament disposed within the bottle. A tip is provided which is insertable into the open end of the squeezable bottle and includes an internal tapered nozzle with the nozzle having increased diameter toward a tip opening. A cap is provided for removable attachment to the bottleneck for sealing the tip opening and a shoulder formed in the bottle proximate the neck and disposed at an angle is provided in order to enhance bubbless flow of the medicament to the nozzle and facilitate tamper proof sealing of the cap.
摘要翻译：容器系统包括具有开口端的颈部的特定容积的挤压瓶和设置在瓶内的药物。提供了可插入可压缩瓶的开口端的尖端，并且包括内部锥形喷嘴，其中喷嘴具有朝向尖端开口的直径增加的直径。提供了用于可拆卸地连接到瓶颈以用于密封尖端开口的盖，并且提供形成在瓶中靠近颈部并以一定角度设置的肩部，以便增强药剂到喷嘴的无气泡流动，并且便于防止这顶帽子。

3. 发明申请

US20060243696A1 Tip design for reducing capillary leakage and water loss for plastic container closures 审中-公开
标题翻译：尖端设计，用于减少塑料容器封闭件的毛细管泄漏和水分流失
公开(公告)号：US20060243696A1
公开(公告)日：2006-11-02
申请号：US11115563
申请日：2005-04-27
申请人： Lon Spada , Scott Gerondale , John Dries
发明人： Lon Spada , Scott Gerondale , John Dries
IPC分类号： B65D45/00 , B65D39/08 , B65D45/32
CPC分类号： B65D47/122 , B65D53/02
摘要： A plastic container closure includes a bottle having an open end with a circumferential bottle shoulder and a tip insertable into the bottle opened end with a tip shoulder overlaying the bottle shoulder. The compressible seal ring is provided and disposed between the bottle shoulder and the tip shoulder and a tip-covering cap engagable with the bottle and the cap compressed to the seal.
摘要翻译：塑料容器封闭件包括具有开口端的瓶子，其具有圆周瓶肩部和可插入瓶子开口端的尖端，其顶端肩部覆盖在瓶肩上。可压缩的密封环设置并设置在瓶肩和尖端肩部之间，并且可与瓶子接合的顶盖盖被压缩到密封件上。

4. 发明申请

US20050279779A1 Controlled drop dispensing tip 审中-公开
标题翻译：控制滴液分配头
公开(公告)号：US20050279779A1
公开(公告)日：2005-12-22
申请号：US10860525
申请日：2004-06-03
申请人： Scott Gerondale , Rodney Terwilliger
发明人： Scott Gerondale , Rodney Terwilliger
IPC分类号： B65D47/18 , B65D35/28
CPC分类号： B65D47/18
摘要： A controlled drop dispensing tip includes a body suitable for attachment to a dispensing bottle and a nozzle having a lumen therethrough for flow of liquid formulation. An orifice is provided in the nozzle which is in fluid communication with the lumen therethrough for formulation of droplets. The nozzle is formed from a material enabling uniform droplet dispensment of the liquid formulation independent of downward angular orientation of the tip.
摘要翻译：受控液滴分配尖端包括适于附接到分配瓶的主体和具有用于液体制剂流动的内腔的喷嘴。在喷嘴中设置有一个孔口，该孔口与该管腔流体连通，用于配制液滴。喷嘴由能够均匀地分散液体制剂的液滴形成，而与喷嘴的向下角度取向无关。

5. 发明申请

US20050154399A1 Apparatus for delivery of ocular implants 有权
标题翻译：用于输送眼部植入物的装置
公开(公告)号：US20050154399A1
公开(公告)日：2005-07-14
申请号：US11021947
申请日：2004-12-23
申请人： David Weber , Ingrid Kane , Mike Rehal , Robert Lathrop , Kenny Aptekarev , Jeffrey Etter , Scott Gerondale , Rahul Bhagat , Shawn Davis
发明人： David Weber , Ingrid Kane , Mike Rehal , Robert Lathrop , Kenny Aptekarev , Jeffrey Etter , Scott Gerondale , Rahul Bhagat , Shawn Davis
IPC分类号： A61F2/16 , A61F9/00
CPC分类号： A61F2/167 , A61F9/0017 , A61F9/007
摘要： An apparatus and methods for delivering ocular implants or microimplants. The apparatus is ergonomically designed for ease of use, and a simple manual depression of an actuator produces proportional movement of a linkage causing the implant or microimplant to be ejected through a cannula disposed at the desired location in the eye. Small gauge cannulas are provided for self-sealing methods of delivery.
摘要翻译：用于输送眼部植入物或微量植入物的装置和方法。该装置符合人体工程学设计，易于使用，并且执行器的简单手动按压产生联动装置的成比例的运动，使得植入物或微型植入物通过设置在眼睛中所需位置的套管喷射。提供小尺寸插管用于自密封输送方法。

6. 发明申请

US20060100584A1 Needleless microprotrusion elastoplast system 审中-公开
标题翻译：无针微灌注弹塑性体系
公开(公告)号：US20060100584A1
公开(公告)日：2006-05-11
申请号：US10915792
申请日：2004-08-10
申请人： Orest Olejnik , Robert Lyons , Scott Gerondale
发明人： Orest Olejnik , Robert Lyons , Scott Gerondale
IPC分类号： A61M5/00 , A61K9/70 , A61F13/00
CPC分类号： A61M5/3007 , A61M37/0015 , A61M2037/0023 , A61M2037/003
摘要： A needleless microprotrusion system for infusion of a medicament into a patient includes a plurality of microprotrusions having a length sufficient to penetrate a stratum corneum of the patient. A chemodenervating agent is disposed in a microprotrusions in a substrate is provided for supporting the microprotrusion and conforming the microprotrusions to a selected patient body part in order to enable uniform penetration of the microprotrusions into the corneum.
摘要翻译：用于向患者输注药物的无针微量输注系统包括具有足以穿透患者角质层的长度的多个微突出物。设置在基底中的微突出物中的化学去神经剂用于支撑微注入并将微突起符合到所选择的患者体部分，以便使微突起部均匀地渗入角质层。

7. 发明申请

US20060069358A1 Controlled drop dispensing units 审中-公开
标题翻译：控制液滴分配单元
公开(公告)号：US20060069358A1
公开(公告)日：2006-03-30
申请号：US11225486
申请日：2005-09-13
申请人： Scott Gerondale
发明人： Scott Gerondale
IPC分类号： A61M35/00
CPC分类号： A61F9/0008 , A61M11/00 , A61M11/007 , A61M11/008 , A61M15/0031 , A61M15/0051 , A61M15/0066 , A61M15/0071
摘要： Controlled drop dispensing tube apparatus includes a tube for containing a medicament, a dispensing tip having an aperture in fluid communication with the tube, a collapsible shell for containing the tube, and a mechanism disposed in the shell for comprising the tube in order to force medicament from the tube and through the dispensing tip upon collapsing of the shell.
摘要翻译：受控液滴分配管装置包括用于容纳药物的管，具有与管流体连通的孔的分配尖端，用于容纳管的可收缩壳体，以及设置在壳体中的用于包括管的机构，以便迫使药物在管壳折叠后，从管中通过分配尖端。

8. 发明授权

US07468065B2 Apparatus for delivery of ocular implants 有权
标题翻译：用于输送眼部植入物的装置
公开(公告)号：US07468065B2
公开(公告)日：2008-12-23
申请号：US11021947
申请日：2004-12-23
申请人： David A. Weber , Ingrid Kane , Mike Rehal , Robert L. Lathrop, III , Kenny Aptekarev , Jeffrey Etter , Scott Gerondale , Rahul Bhagat , Shawn Davis
发明人： David A. Weber , Ingrid Kane , Mike Rehal , Robert L. Lathrop, III , Kenny Aptekarev , Jeffrey Etter , Scott Gerondale , Rahul Bhagat , Shawn Davis
IPC分类号： A61F9/00
CPC分类号： A61F2/167 , A61F9/0017 , A61F9/007
摘要： An apparatus and methods for delivering ocular implants or microimplants. The apparatus is ergonomically designed for ease of use, and a simple manual depression of an actuator produces proportional movement of a linkage causing the implant or microimplant to be ejected through a cannula disposed at the desired location in the eye. Small gauge cannulas are provided for self-sealing methods of delivery.
摘要翻译：用于输送眼部植入物或微量植入物的装置和方法。该装置符合人体工程学设计，易于使用，并且执行器的简单手动按压产生联动装置的成比例的运动，使得植入物或微型植入物通过设置在眼睛中所需位置的套管喷射。提供小尺寸插管用于自密封输送方法。

9. 发明申请

US20070098774A1 METHOD OF DELIVERING A MEDICATION 有权
标题翻译：递送药物的方法
公开(公告)号：US20070098774A1
公开(公告)日：2007-05-03
申请号：US11601258
申请日：2006-11-16
申请人： Orest Olejnik , Robert Lyons , Scott Gerondale
发明人： Orest Olejnik , Robert Lyons , Scott Gerondale
IPC分类号： A61M5/00 , A61K9/70
CPC分类号： A61M5/3007 , A61M37/0015 , A61M2037/0023 , A61M2037/003
摘要： A needleless microprotrusion method for infusion of a medicament into a patient includes disposing a substrate plurality of microprotrusions onto a patients' palm. A chemodenervating agent is disposed for delivery by the microprotrusions and the substrate supports and conforms the microprotrusions to the patients' palm in order to enable uniform penetration of the microprotrusions into the corneum.
摘要翻译：用于将药物输注入患者的无针微灌注方法包括将多个微突起物置于患者手掌上。化学去神剂被设置用于通过微突起物和基底支撑物递送，并使微突起符合患者的手掌，以便使微突起物均匀地渗透到角质层中。

10. 发明申请

US20070098773A1 Needleless microprotrusion elastoplast system 有权
标题翻译：无针微灌注弹塑性体系
公开(公告)号：US20070098773A1
公开(公告)日：2007-05-03
申请号：US11600576
申请日：2006-11-16
申请人： Orest Olejnik , Robert Lyons , Scott Gerondale
发明人： Orest Olejnik , Robert Lyons , Scott Gerondale
IPC分类号： A61K9/70 , A61M5/00
CPC分类号： A61M5/3007 , A61M37/0015 , A61M2037/0023 , A61M2037/003
摘要： A needleless microprotrusion system for infusion of a medicament into a patient includes a plurality of microprotrusions having a length sufficient to penetrate a stratum corneum of the patient. A chemodenervating agent is disposed for delivery by the microprotrusions and a substrate is provided for supporting the microprotrusions and conforming the microprotrusions to a patient's palm in order to enable uniform penetration of the microprotrusions into the corneum.
摘要翻译：用于向患者输注药物的无针微量输注系统包括具有足以穿透患者角质层的长度的多个微突出物。设置化学去神剂用于通过微突起输送，并且提供用于支撑微突起并使微突起符合患者手掌的基底，以便使微突起均匀地渗入角质层。

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