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    • 1. 发明申请
    • System and method for marking textiles with nucleic acids
    • 用核酸标记纺织品的系统和方法
    • US20050112610A1
    • 2005-05-26
    • US10825968
    • 2004-04-15
    • Lawrence LeeDonald AlexanderJun ShueBenjamin LiangChung-Shung Chen
    • Lawrence LeeDonald AlexanderJun ShueBenjamin LiangChung-Shung Chen
    • B05D5/00B05D7/00C12Q1/68D04H20060101D04H1/587D04H1/64
    • D06M15/03C12Q1/6876D04H1/587D04H1/64Y10T442/2508
    • A method for authenticating a textile material that is initiated by selecting a unique nucleic acid marker having a specific length and a specific sequence. A media that causes the unique nucleic acid marker to adhere to a fibrous material is then selected. The method then proceeds to generate a nucleic acid marker mixture by mixing the media with the nucleic acid marker. The nucleic acid marker mixture is then applied to the fibrous material. A marked fibrous material is produced by marking the fibrous material with the nucleic acid marker. The textile material is manufactured with the marked fibrous material. The textile material is then authenticated by detecting the unique nucleic acid marker with primers that are specific to the unique nucleic acid. In an alternative embodiment, the media is used as a topical treatment for the fibrous material. In another alternative embodiment, the media is a carrier media that can be added to one or more fiber manufacturing processes without affecting each of the manufacturing processes. In yet another alternative embodiment, a viscous solution for fiber spinning is selected and mixed with the nucleic acid marker to generate a viscous dope that is extruded through an opening in a spinneret to form a marked fiber that is used to generate the textile material.
    • 通过选择具有特定长度和特定序列的唯一核酸标记来启动织物材料的认证方法。 然后选择使独特的核酸标记物粘附到纤维材料上的介质。 然后该方法进行以通过将培养基与核酸标记物混合来产生核酸标记混合物。 然后将核酸标记混合物施加到纤维材料上。 标记的纤维材料通过用核酸标记物标记纤维材料来制备。 纺织材料用标记的纤维材料制成。 然后通过用独特的核酸特异性的引物检测独特的核酸标记鉴定纺织材料。 在替代实施例中,介质用作纤维材料的局部治疗。 在另一替代实施例中,介质是可以添加到一个或多个光纤制造工艺而不影响每个制造工艺的载体介质。 在另一替代实施例中,选择纤维纺丝的粘性溶液并与核酸标记物混合以产生通过喷丝头中的开口挤出以形成用于产生纺织材料的标记纤维的粘性涂料。
    • 2. 发明申请
    • Method of marking solid or liquid substances with nucleic acid for anti-counterfeiting and authentication
    • 用核酸标记固体或液体物质进行防伪和认证的方法
    • US20050008762A1
    • 2005-01-13
    • US10748412
    • 2003-12-29
    • Jue-Jei SheuLin-Lin ChenEmma ChenBenjamin Liang
    • Jue-Jei SheuLin-Lin ChenEmma ChenBenjamin Liang
    • G09F3/00B05D3/00
    • G09F3/00
    • The present invention relates to a method of marking solid or liquid substances with nucleic acid for anti-counterfeiting and authentication, specifically to a method for marking solid or liquid substances with nucleic acid dissolved in a water insoluble medium. Through the addition of an intermediate solution, the miscibility between the nucleic acid solution and the medium is increased and forms a homogenous solution. For marking solid substances or articles, the water-insoluble medium containing known nucleic acid taggants is spread on the target solid substances or articles. After drying, nucleic acids protected by the water-insoluble medium adhere on surface of the object. For marking liquid, the target liquid is mixed with the water-insoluble media containing known nucleic acid taggants. As a result, the target liquid is labeled with nucleic acid.
    • 本发明涉及使用用于防伪和认证的核酸标记固体或液体物质的方法,具体涉及用溶解在水不溶性介质中的核酸来标记固体或液体物质的方法。 通过添加中间溶液,核酸溶液和培养基之间的混溶性增加并形成均匀的溶液。 为了标记固体物质或物品,将含有已知核酸标记的水不溶性介质扩散到目标固体物质或物品上。 干燥后,由水不溶性介质保护的核酸粘附在物体的表面上。 为了标记液体,将目标液体与含有已知核酸标记物的水不溶性介质混合。 结果,目标液体用核酸标记。
    • 4. 发明授权
    • Method of marking solid or liquid substances with nucleic acid for anti-counterfeiting and authentication
    • 用核酸标记固体或液体物质进行防伪和认证的方法
    • US07115301B2
    • 2006-10-03
    • US10748412
    • 2003-12-29
    • Jue-Jei SheuLin-Lin ChenEmma ChenBenjamin Liang
    • Jue-Jei SheuLin-Lin ChenEmma ChenBenjamin Liang
    • B05D7/24
    • G09F3/00
    • A method of marking a solid article or substance includes the steps of dissolving a water-insoluble medium in a first solvent to form a first mixture, mixing a nucleic acid solution with an intermediate solution to form a second mixture, mixing the second mixture with the first mixture to form a homogenous third mixture, marking the article or substance with the third mixture containing the nucleic acid; and drying the marked article or substance. Through the addition of an intermediate solution, the miscibility between the nucleic acid solution and the medium is increased and a homogenous solution is formed. For marking solid substances or articles, the water-insoluble medium containing known nucleic acid taggants is spread on the target solid substances or articles. For marking liquid, the target liquid is mixed with the water-insoluble media containing known nucleic acid taggants. As a result, the target liquid is labeled with nucleic acid.
    • 标记固体制品或物质的方法包括以下步骤:将水不溶性介质溶解在第一溶剂中以形成第一混合物,将核酸溶液与中间溶液混合以形成第二混合物,将第二混合物与 第一混合物以形成均匀的第三混合物,用含有核酸的第三混合物标记物品或物质; 并干燥标记的物品或物质。 通过添加中间溶液,增加核酸溶液和介质之间的混溶性,形成均匀的溶液。 为了标记固体物质或物品,将含有已知核酸标记的水不溶性介质扩散到目标固体物质或物品上。 为了标记液体,将目标液体与含有已知核酸标记物的水不溶性介质混合。 结果,目标液体用核酸标记。
    • 6. 发明申请
    • Novel nucleic acid based steganography system and application thereof
    • 新型基于核酸的隐写术系统及其应用
    • US20050059059A1
    • 2005-03-17
    • US10909431
    • 2004-08-03
    • Benjamin Liang
    • Benjamin Liang
    • C12N15/09C12Q1/68G09C1/02H04L9/00G01N33/48G01N33/50G06F19/00H04L9/32
    • H04L9/00C12Q1/6816C12Q2563/185C12Q2533/107C12Q2531/113
    • Disclosed are nucleic acid based encryption technique and the corresponding decryption method. The encryption method comprises the steps of dividing an original nucleic acid sequence corresponding to a predefined message according to a predetermined cipher table into a plurality of fragmented nucleic acid sequences, ligating the fragmented nucleotide sequences with oligomers for sequence analysis and oligomers for sequence recognition. The corresponding decryption method comprises the steps of using the corresponding PCR primers and sequencing primers to determine the sequence information of the fragmented nucleotide sequences, combining with the information provided by oligomers for order arrangement to decode the original nucleotide sequence. This multiple encryption method can provide more security to a predefined message desired to keep confidential.
    • 公开了基于核酸的加密技术和相应的解密方法。 该加密方法包括以下步骤:将根据预定密码表的预定义消息对应的原始核酸序列划分成多个片段化的核酸序列,将片段化的核苷酸序列与用于序列分析的寡聚体连接,并用于序列识别。 相应的解密方法包括以下步骤:使用相应的PCR引物和测序引物来确定片段化核苷酸序列的序列信息,结合低聚物提供的信息进行顺序排列以解码原始核苷酸序列。 这种多重加密方法可以为希望保密的预定义消息提供更多的安全性。