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1. 发明授权

US06846313B1 One-piece biocompatible absorbable rivet and pin for use in surgical procedures 失效
标题翻译：一体式生物相容性可吸收铆钉和针脚用于外科手术
公开(公告)号：US06846313B1
公开(公告)日：2005-01-25
申请号：US09667729
申请日：2000-09-22
申请人： Laurel L. Rogers , Mariann Sayer , David W. Overaker , Shawn T. Huxel , Kevin Cooper , Dennis D. Jamiolkowski , Joseph R. Thomas
发明人： Laurel L. Rogers , Mariann Sayer , David W. Overaker , Shawn T. Huxel , Kevin Cooper , Dennis D. Jamiolkowski , Joseph R. Thomas
IPC分类号： A61B17/58 , A61B17/68 , A61B17/56
CPC分类号： A61B17/68
摘要： A bioabsorbable rivet and pin fastener is formed as an elongated unit that may be used for anchoring, or for attachment of a fixation plate. The rivet has a head mechanically connected to two or more legs that extend generally distally from the head and may flex outwardly from a central rivet axis. The pin is integral with the rivet and oriented along the central axis by a connection such as a web or a plurality of braces, forming an integral, aligned, one-piece assembly that may, for example, be molded as a single piece. The connection breaks under force as the pin is driven into the rivet, so that the pin contacts internal surfaces of the legs and pushes the legs outward into frictional engagement with the surrounding bone. The one-piece assembly may be formed in a gated mold having a central pin with a relief passage that defines the braces between upper and lower portions of the rivet. The braces so formed at the weld line readily part from the mold, and are easily sheared when the pin is advanced during installation of the rivet.
摘要翻译：生物可吸收的铆钉和销紧固件形成为可用于锚定或用于附接固定板的细长单元。铆钉具有机械连接到两个或更多个腿的头部，该两个或多个腿部从头部大致向远侧延伸并且可以从中心铆钉轴线向外弯曲。该销与铆钉成一体并且通过诸如幅材或多个支架的连接件沿着中心轴线定向，形成整体的，对齐的整体式组件，其可以例如被模制成单件。当销被驱动到铆钉中时，连接断裂，使得销接触腿的内表面并向外推动腿与周围的骨摩擦接合。一体式组件可以形成在具有中心销的门控模具中，该中心销具有在铆钉的上部和下部之间限定支架的释放通道。在焊接线处形成的支架容易地与模具成一部分，并且在铆钉安装期间当销前进时容易剪切。

2. 发明授权

US06241732B1 Biocompatible absorbable rivets and pins for use in surgical procedures 有权
标题翻译：生物相容的可吸收铆钉和针脚用于外科手术
公开(公告)号：US06241732B1
公开(公告)日：2001-06-05
申请号：US09185051
申请日：1998-11-03
申请人： David W. Overaker , Shawn T. Huxel , Kevin Cooper , Dennis D. Jamiolkowski
发明人： David W. Overaker , Shawn T. Huxel , Kevin Cooper , Dennis D. Jamiolkowski
IPC分类号： A61B1756
CPC分类号： A61B17/68
摘要： A bioabsorbable rivet and pin fastening device that may be used for attachment of a fixation plate to bone is described herein. The rivet having a head that is mechanically connected to two or more legs that extend generally distally from the head. The pin being radially compressible and less compliant than the legs of the rivet. The pin when inserted into the rivet will contact the internal surface of said legs to apply force on said legs in a direction perpendicular to the central axis to frictionally engage with the adjacent bone.
摘要翻译：本文描述了可用于将固定板附接到骨骼上的生物可吸收的铆钉和销固定装置。该铆钉具有机械连接到两个或更多个腿部的头部，该两个或多个腿部从头部大致向远侧延伸。该销可径向压缩，并且比铆钉的腿部柔顺。当插入铆钉中时，销将接触所述腿部的内表面，以在垂直于中心轴线的方向上对所述腿施加力以与邻近的骨摩擦接合。

3. 发明授权

US5681351A Suture clip suitable for use on monofilament sutures 失效
标题翻译：适合用于单丝缝线的缝合夹
公开(公告)号：US5681351A
公开(公告)日：1997-10-28
申请号：US327248
申请日：1994-10-21
申请人： Dennis D. Jamiolkowski , Shawn T. Huxel , Daniel C. Rosenman
发明人： Dennis D. Jamiolkowski , Shawn T. Huxel , Daniel C. Rosenman
IPC分类号： A61B17/06 , A61B17/00 , A61B17/04
CPC分类号： A61B17/0487 , A61B17/0401 , A61B2017/00004 , A61B2017/0445 , A61B2017/0454 , Y10T24/3969 , Y10T24/3996
摘要： The present invention provides a suture clip for attachment to at least one suture comprising a suture clip body having a central longitudinal axis, a proximal end, a distal end, an inner surface, an outer surface and a proximal surface, wherein the inner surface forms a passage that is substantially parallel to the longitudinal axis and is connected to the outer surface by a longitudinal slot which extends from the distal end to the proximal end of the suture clip body and the proximal surface has a major dimension at least five times larger than the diameter of said suture and a collar disposed about said suture clip body engaging the outer surface of the suture clip body to deflect the inner surface to frictionally engage the suture. Also described herein are methods of using this suture clip in surgical procedures.
摘要翻译：本发明提供一种用于连接至至少一条缝合线的缝线夹，其包括具有中心纵向轴线，近端，远端，内表面，外表面和近端表面的缝合夹主体，其中内表面形成通道，其基本上平行于纵向轴线并且通过纵向槽连接到外表面，所述纵向狭槽从缝合夹主体的远端延伸到近端，并且近端表面的主要尺寸至少大于所述缝合线的直径和围绕所述缝合夹主体设置的衣领与缝合夹主体的外表面接合以使内表面偏转以摩擦地接合缝合线。本文还描述了在外科手术中使用该缝合夹的方法。

4. 发明授权

US06503259B2 Expandable anastomotic device 有权
公开(公告)号：US06503259B2
公开(公告)日：2003-01-07
申请号：US09748311
申请日：2000-12-27
申请人： Shawn T. Huxel , John McAllen, III , David W. Overaker
发明人： Shawn T. Huxel , John McAllen, III , David W. Overaker
IPC分类号： A61B1708
CPC分类号： A61B17/115 , A61B17/0643 , A61B17/32053 , A61B2017/00725 , A61B2017/0641 , A61B2017/0647 , A61B2017/1107 , A61B2017/1132 , Y10S227/902 , Y10S411/923
摘要： A surgical fastening system includes a fastener having a plurality of individual fastener pairs each having a piercing element with a pin that pierces the tissue to be repaired and a receiver portion that interlocks with the pin of a corresponding piercing element. A fastener dispenser holds the piercing elements and receiver elements in relative juxtaposition and in a predetermined geometric configuration, such as a circle. After the tissues to be joined are positioned between the piercing and receiving elements held in the dispenser, the dispenser is adjusted to draw the elements together capturing the tissue therebetween. The dispenser then pushes the piercing elements through the tissue and into the receiving elements causing the elements to interlock. Because the anastomosed junction is formed by a plurality of independent pairs, the junction retains flexibility. When used to anastomose a tubular organ, the fastener allows radial expansion of the organ permitting peristalsis.

5. 发明授权

US5971987A Biocompatible absorbable polymer fastener and driver for use in surgical procedures 有权
标题翻译：生物兼容的可吸收聚合物紧固件和用于外科手术的驱动器
公开(公告)号：US5971987A
公开(公告)日：1999-10-26
申请号：US157199
申请日：1998-09-18
申请人： Shawn T. Huxel , David W. Overaker
发明人： Shawn T. Huxel , David W. Overaker
IPC分类号： A61B17/00 , A61B17/86 , A61B17/88 , A61B19/00 , A61L31/06
CPC分类号： A61B17/8875 , A61B17/8605 , A61L31/06 , A61B2017/00004 , A61B2090/037
摘要： A biocompatible fastener that may be used for attachment of a fixation plate to bone is described herein, where the fastener has features that facilitate its deployment in a surgical environment. The fastener is composed of a screw, having a threaded shaft and slotted head, and a detachable body that is used for deploying the screw and is then broken away and discarded. The slot in the head of the screw has stress concentrating notch features that direct the fracture lines into the screw head upon detachment of the secondary body, thus ensuring that the screw head surface remains smooth after deployment. A suitable driver for applying the fastener is also described.
摘要翻译：本文描述了可用于将固定板附接到骨骼上的生物相容性紧固件，其中紧固件具有便于其在手术环境中展开的特征。紧固件由具有螺纹轴和开口头部的螺钉和用于展开螺钉的可拆卸本体组成，然后被分解和丢弃。螺钉头部的狭槽具有应力集中切口特征，其在第二主体脱离时将断裂线引导到螺钉头中，从而确保螺钉头表面在展开后保持平滑。还描述了用于施加紧固件的合适的驱动器。

6. 发明授权

US5550172A Utilization of biocompatible adhesive/sealant materials for securing surgical devices 失效
标题翻译：利用生物相容的粘合剂/密封剂材料来固定外科手术器械
公开(公告)号：US5550172A
公开(公告)日：1996-08-27
申请号：US385015
申请日：1995-02-07
申请人： Donald W. Regula , Kevin Cooper , Michael F. Bregen , Shawn T. Huxel , Daniel C. Rosenman
发明人： Donald W. Regula , Kevin Cooper , Michael F. Bregen , Shawn T. Huxel , Daniel C. Rosenman
IPC分类号： A61L24/00 , A61L24/02 , A61L24/04 , A61L24/06 , A61L27/00 , C08K5/10 , A61B17/56 , A61B17/58 , C01B15/16
CPC分类号： A61L24/046 , A61L24/02 , A61L24/06
摘要： A process for enhancing the security of implantable surgical devices secured to bone tissue comprising implanting in bone tissue a surgical device with a biocompatible adhesive and/or sealant selected from the group consisting of: p1 (a) a material made from monomers of the formula:CHR.sup.1 .dbd.CX.sup.1 Y.sup.1 wherein X.sup.1 and Y.sup.1 are each strong electron withdrawing groups, and R.sup.1 is hydrogen or, provided that X.sup.1 and Y.sup.1 are both cyano groups, a C.sub.1 -C.sub.4 alkyl group;(b) a semi-crystalline aliphatic poly(ester) of the formula:[--0--R.sup.11 --C(0)--].sub.y, wherein R.sup.11 is selected from the group consisting of --CR.sup.12 H--, --(CH.sub.2).sub.3 --0--, --CH.sub.2 --CH.sub.2 --O--CH.sub.2 --, CR.sub.12 H--CH.sub.2, --(CH.sub.2).sub.4 --, --(CH.sub.2).sub.z --O--C(O)-- and --(CH.sub.2).sub.z --C(O)--CH.sub.2 --; R.sup.12 is hydrogen or methyl; z is an integer in the range of from 1 to 7 and y is an integer in the range of from about 10 to about 20,000; and(c) a slurry of water and a calcium containing compounds with the general formula:M.sup.2+.sub.10-n N.sup.1+.sub.2n (WO.sub.4.sup.3-).sub.6 mU.sup.2- where n is an integer from 1 to 10, and m is 2 when x is 1, or m is 1 when x is 2, M and N are alkali or alkaline earth metals; WO.sub.4 is an acid radical and w is phosphorus, vanadium, sulfur, silicon, or is substituted in whole or part with carbonate (CO.sub.3.sup.2-); and U is a halide, hydroxide, or carbonate; provided in an amount effective to increase the amount of force necessary to remove the implanted surgical device. Additionally provided is a surgical device that is at least partially coated with at least one biocompatible adhesive and/or sealant.
摘要翻译：一种用于增强固定到骨组织的可植入手术装置的安全性的方法，包括在骨组织中植入具有选自以下的生物相容性粘合剂和/或密封剂的手术装置：p1（a）由下式的单体制成的材料： CHR1 = CX1Y1，其中X1和Y1各自是强吸电子基团，R1是氢，或者X1和Y1都是氰基，C1-C4烷基; （b）下式的半结晶脂族聚（酯）：[-0-R11-C（O） - ] y，其中R11选自-CR12H - ， - （CH2）3-0 - ， - CH 2 - （CH 2）4 - ， - （CH 2）z OC（O） - 和 - （CH 2）z C（O） R 12是氢或甲基; z是1至7的整数，y是约10至约20,000的整数; 和（c）水和含钙化合物的浆料，通式为：M2 + 10-nN1 + 2n（WO43-）6mU2-其中n为1至10的整数，当x为1时，m为2，或当x为2时m为1，M和N为碱金属或碱土金属; WO4是酸基，w是磷，钒，硫，硅，或全部或部分被碳酸酯（CO32-）取代; U是卤化物，氢氧化物或碳酸盐; 提供有效量以增加去除植入的手术装置所需的力的量。另外提供了至少部分地涂覆有至少一种生物相容性粘合剂和/或密封剂的手术装置。

7. 发明申请

US20130060190A9 METHOD AND APPARATUS FOR REPAIRING A TENDON OR LIGAMENT 有权
公开(公告)号：US20130060190A9
公开(公告)日：2013-03-07
申请号：US12716724
申请日：2010-03-03
申请人： Leonard Gordon , Shawn T. Huxel , Mari Susan Truman , Alan B. Miller
发明人： Leonard Gordon , Shawn T. Huxel , Mari Susan Truman , Alan B. Miller
IPC分类号： A61M29/00 , A61B17/70
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/1146 , A61B17/3468 , A61B2017/0414 , A61B2017/044 , A61B2017/0472 , A61B2017/06057 , A61B2017/1103 , A61F2/0811 , A61M25/0023 , A61M29/00
摘要： A method and apparatus for reattaching the opposed ends of a member, such as a tendon, ligament or bone, during preparing and healing of the member using a surgical repair device that can be securely attached to the member and then safely guided through tortuous anatomy for reattachment and repair. The repair device further includes structural means so as to secure opposed ends of the member against separation during healing. Devices for aiding in the positioning of the surgical repair device are provided.

8. 发明申请

US20100237128A1 METHOD AND APPARATUS FOR DELIVERING A SHAPE MEMORY ARTICLE TO A SURGICAL SITE 有权
标题翻译：将形状记忆文章传送到外科手术的方法和装置
公开(公告)号：US20100237128A1
公开(公告)日：2010-09-23
申请号：US12708973
申请日：2010-02-19
申请人： Alan B. Miller , Shawn T. Huxel , Richard Thomas Briganti
发明人： Alan B. Miller , Shawn T. Huxel , Richard Thomas Briganti
IPC分类号： A61B17/068
CPC分类号： A61B17/068 , A61B17/0642 , A61B17/0644 , A61B17/0682 , A61B17/10 , A61B2017/0023 , A61B2017/00867 , A61B2017/0645 , A61B2090/034
摘要： The invention pertains to a method and apparatus for delivering an article formed of a shape memory alloy to a surgical implantation site.
摘要翻译：本发明涉及一种用于将由形状记忆合金形成的制品输送到手术植入部位的方法和装置。

9. 发明授权

US5599852A Injectable microdispersions for soft tissue repair and augmentation 失效
标题翻译：用于软组织修复和增强的注射微分散体
公开(公告)号：US5599852A
公开(公告)日：1997-02-04
申请号：US324543
申请日：1994-10-18
申请人： Angelo G. Scopelianos , Steven C. Arnold , Rao S. Bezwada , Mark B. Roller , Shawn T. Huxel
发明人： Angelo G. Scopelianos , Steven C. Arnold , Rao S. Bezwada , Mark B. Roller , Shawn T. Huxel
IPC分类号： A61J1/05 , A61F2/02 , A61F2/12 , A61K9/00 , A61K9/107 , A61K47/34 , A61L27/00 , A61L27/18 , C08K5/15 , A61F2/00 , A61M5/00 , C08L3/00
CPC分类号： A61K9/0024 , A61K47/34 , A61L27/18
摘要： The present invention provides injectable, bioabsorbable microdispersions suitable for use as a soft tissue repair or augmentation material in animals comprising a fluid carrier that is a liquid polymer selected from the group consisting of liquid polymers and a particulate material. Additionally, the present invention also discloses methods of using these microdispersions for tissue augmentation and repair as well as kits which include prefilled containers to facilitate the use of these materials.
摘要翻译：本发明提供了适合用作动物中的软组织修复或增加材料的可注射的，生物可吸收的微分散体，其包含作为液体聚合物的流体载体，所述液体聚合物选自液体聚合物和颗粒材料。此外，本发明还公开了使用这些微分散体进行组织增强和修复的方法以及包括预装容器以便于使用这些材料的试剂盒。

10. 发明授权

US06648811B2 Brachytherapy cartridge including absorbable and autoclaveable spacer 有权
标题翻译：近距离放射治疗药筒包括可吸收和可高压灭菌的间隔物
公开(公告)号：US06648811B2
公开(公告)日：2003-11-18
申请号：US09780437
申请日：2001-02-09
申请人： Thomas J. Sierocuk , Nicholas M. Popadiuk , John J. Karl , Shawn T. Huxel
发明人： Thomas J. Sierocuk , Nicholas M. Popadiuk , John J. Karl , Shawn T. Huxel
IPC分类号： A61M3600
CPC分类号： A61M37/0069 , A61N5/1007 , A61N5/1027 , A61N2005/101 , A61N2005/1023
摘要： The present invention is directed to a brachytherapy seed delivery system which includes a seed cartridge including a central channel, a plurality of brachytherapy seeds disposed within the central channel and a plurality of absorbable, dimensionally stable spacers disposed within the central channel. The present invention is further directed to a method of loading a brachytherapy seed delivery system including the steps of: providing a seed cartridge including a central channel, seeds and spacers as described above; connecting the brachytherapy seed cartridge to a brachytherapy needle including a cannula; and forcing the seeds out of the brachytherapy seed cartridge into the cannula. The present invention is further directed to an improved brachytherapy method including inserting the brachytherapy needle of the brachytherapy seed delivery system recited above into a human organ; and forcing the seeds and the spacer through the cannula of the brachytherapy needle and into the human organ.
摘要翻译：本发明涉及一种近距离放射治疗种子递送系统，其包括种子筒，其包括中央通道，设置在中心通道内的多个近距离放射治疗种子和设置在中心通道内的多个可吸收的尺寸稳定的间隔物。本发明还涉及一种装载近距离放射治疗种子递送系统的方法，包括以下步骤：提供包括如上所述的中心通道，种子和间隔物的种子仓; 将近距离放射治疗种子柱连接到包括插管的近距离放射治疗针; 并将种子从近距离放射治疗种子柱推入插管中。本发明进一步涉及一种改进的近距离放射治疗方法，包括将上述近距离放射治疗种子递送系统的近距离放射治疗针插入人体器官; 并迫使种子和间隔物通过近距离放射治疗针的插管进入人体器官。

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