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1. 发明申请

US20130265031A1 NANOGAP SENSOR AND METHOD OF MANUFACTURING THE SAME 有权
标题翻译： NANOGAP传感器及其制造方法
公开(公告)号：US20130265031A1
公开(公告)日：2013-10-10
申请号：US13605711
申请日：2012-09-06
申请人： Jeo-young SHIM , Tae-han JEON , Kun-sun EOM , Dong-ho LEE , Hee-jeong JEONG , Seong-ho CHO
发明人： Jeo-young SHIM , Tae-han JEON , Kun-sun EOM , Dong-ho LEE , Hee-jeong JEONG , Seong-ho CHO
IPC分类号： H01L29/15 , H01L21/42 , G01N27/00 , B82Y15/00 , B82Y40/00
CPC分类号： G01N15/1031 , B82Y15/00 , G01N15/1056 , G01N33/48721 , G01N2015/0038
摘要： A nanogap sensor includes a first layer in which a micropore is formed; a graphene sheet disposed on the first layer and including a nanoelectrode region in which a nanogap is formed, the nanogap aligned with the micropore; a first electrode formed on the grapheme sheet; and a second electrode formed on the graphene sheet, wherein the first electrode and the second electrode are connected to respective ends of the nanoelectrode region.
摘要翻译：纳米隙传感器包括其中形成微孔的第一层; 设置在所述第一层上并且包括其中形成有纳米隙的纳米电极区域的所述纳米隙与所述微孔对准的石墨烯片; 形成在所述刻画片上的第一电极; 以及形成在所述石墨烯片上的第二电极，其中所述第一电极和所述第二电极连接到所述纳米电极区域的各个端部。

2. 发明申请

US20130161194A1 NANOPORE DEVICE, METHOD OF FABRICATING THE SAME, AND DNA DETECTION APPARATUS INCLUDING THE SAME 有权
标题翻译：纳米装置，其制造方法和包括其的DNA检测装置
公开(公告)号：US20130161194A1
公开(公告)日：2013-06-27
申请号：US13572516
申请日：2012-08-10
申请人： Tae-han JEON , Jeo-young SHIM , Kun-sun EOM , Dong-ho LEE , Hee-jeong JEONG
发明人： Tae-han JEON , Jeo-young SHIM , Kun-sun EOM , Dong-ho LEE , Hee-jeong JEONG
IPC分类号： G01N27/447 , C23C14/34 , B82Y40/00 , B82Y99/00 , B82Y30/00
CPC分类号： G01N27/3278 , B82Y15/00 , B82Y30/00 , B82Y40/00 , C23C14/34 , G01N33/48721
摘要： A nanopore device including a nanopore formed by penetrating a thin layer, a nanochannel formed at an entrance of the nanopore, and a filler in the nanochannel, as well as a method of fabricating the nanopore device and an apparatus including the nanopore device.
摘要翻译：包括通过穿透薄层形成的纳米孔，在纳米孔的入口处形成的纳米通道和纳米通道中的填料的纳米孔装置，以及制造纳米孔装置的方法和包括纳米孔装置的装置。

3. 发明申请

US20130264206A1 BIOMOLECULE DETECTION APPARATUS INCLUDING PLURALITY OF ELECTRODES 有权
标题翻译：生物分子检测装置，包括电极的多样性
公开(公告)号：US20130264206A1
公开(公告)日：2013-10-10
申请号：US13614881
申请日：2012-09-13
申请人： Kun-sun EOM , Dong-ho LEE , Jeo-young SHIM , Hee-jeong JEONG , Tae-han JEON
发明人： Kun-sun EOM , Dong-ho LEE , Jeo-young SHIM , Hee-jeong JEONG , Tae-han JEON
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： C12Q1/68 , G01N33/48721 , C12Q2565/631
摘要： A biomolecule detection apparatus comprising a nanopore device having a front surface and rear surface and including a nanopore having a nano-sized diameter; a reservoir disposed adjacent to a rear surface of the nanopore device; and a power supply unit comprising a first electrode disposed in a front of the nanopore device; a second electrode disposed inside the reservoir; and a third electrode disposed adjacent the nanopore and between the first electrode and the second electrode; as well as a method of using the biomolecule detection apparatus to detect a biomolecule in a sample.
摘要翻译：一种生物分子检测装置，包括具有前表面和后表面的纳米孔装置，并且包括具有纳米尺寸直径的纳米孔; 设置在所述纳米孔装置的后表面附近的储存器; 以及电源单元，包括设置在所述纳米孔装置的前面的第一电极; 设置在所述储存器内的第二电极; 以及与所述纳米孔相邻并且位于所述第一电极和所述第二电极之间的第三电极; 以及使用生物分子检测装置检测样品中的生物分子的方法。

4. 发明申请

US20130161192A1 APPARATUS AND METHOD FOR LINEARLY TRANSLOCATING NUCLEIC ACID MOLECULE THROUGH AN APERTURE 审中-公开
标题翻译：通过孔径直线转录核酸分子的装置和方法
公开(公告)号：US20130161192A1
公开(公告)日：2013-06-27
申请号：US13572496
申请日：2012-08-10
申请人： Jeo-young SHIM , Dong-ho LEE , Tae-han JEON , Seong-ho CHO , Kun-sun EOM , Hee-jeong JEONG
发明人： Jeo-young SHIM , Dong-ho LEE , Tae-han JEON , Seong-ho CHO , Kun-sun EOM , Hee-jeong JEONG
IPC分类号： C25B7/00 , B82Y99/00 , B82Y30/00
CPC分类号： C12Q1/6869 , B82Y30/00 , G01N33/48721 , C12Q2565/631
摘要： An apparatus and method for linearly translocating nucleic acid molecules through an aperture at a reduced rate.
摘要翻译：用于以降低的速率线性转位核酸分子通过孔的装置和方法。

5. 发明申请

US20140202866A1 NANOSENSOR AND METHOD OF MANUFACTURING SAME 有权
标题翻译：纳米传感器及其制造方法
公开(公告)号：US20140202866A1
公开(公告)日：2014-07-24
申请号：US14224770
申请日：2014-03-25
申请人： Jeo-young SHIM , Tae-han Jeon , Dong-ho Lee , Hee-jeong Jeong , Seong-ho Cho
发明人： Jeo-young SHIM , Tae-han Jeon , Dong-ho Lee , Hee-jeong Jeong , Seong-ho Cho
IPC分类号： G01N27/447
CPC分类号： G01N27/44791 , G01N33/48721
摘要： A nanosensor may include a substrate that has a hole formed therein, a first insulating layer that is disposed on the substrate and has a nanopore formed therein, first and second electrodes that are disposed on the first insulating layer and are spaced apart from each other, first and second electrode pads that are disposed on the first and second electrodes, respectively, and a protective layer disposed on the first and second electrode pads. A method of manufacturing a nanosensor may include forming a first insulating layer, graphene, and a metal layer on a substrate, patterning the metal layer and the graphene, forming a protective layer on a portion of the graphene and the metal layer, exposing a portion of the graphene by removing a portion of the protective layer, forming a hole in the substrate, and forming a nanopore in the first insulating layer and the graphene to be connected to the hole.
摘要翻译：纳米传感器可以包括其中形成有孔的基板，设置在基板上并且在其中形成有纳米孔的第一绝缘层，设置在第一绝缘层上并彼此间隔开的第一和第二电极，分别设置在第一和第二电极上的第一和第二电极焊盘以及设置在第一和第二电极焊盘上的保护层。制造纳米传感器的方法可以包括在基板上形成第一绝缘层，石墨烯和金属层，图案化金属层和石墨烯，在石墨烯和金属层的一部分上形成保护层，将部分通过去除保护层的一部分，在衬底中形成孔，并在第一绝缘层中形成纳米孔和与孔连接的石墨烯。

6. 发明申请

US20120325664A1 NANOSENSOR AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：纳米传感器及其制造方法
公开(公告)号：US20120325664A1
公开(公告)日：2012-12-27
申请号：US13410883
申请日：2012-03-02
申请人： Jeo-young SHIM , Tae-han JEON , Dong-ho LEE , Hee-jeong JEONG , Seong-ho CHO
发明人： Jeo-young SHIM , Tae-han JEON , Dong-ho LEE , Hee-jeong JEONG , Seong-ho CHO
IPC分类号： G01N27/453 , B05D3/10 , B44C1/22
CPC分类号： G01N27/44791 , G01N33/48721
摘要： A nanosensor comprising a substrate having a hole; a first insulating layer disposed on the substrate and having a first nanopore at a location corresponding to the hole in the substrate; first and second electrodes disposed on the first insulating layer, wherein the first and second electrodes are spaced apart from each other with the first nanopore positioned therebetween; a first electrode pad disposed on at least a portion of the first electrode; a second electrode pad disposed on at least a portion of the second electrode; and a protective layer disposed on at least a portion of the first and second electrode pads; as well as a method for manufacturing same.
摘要翻译：一种纳米传感器，包括具有孔的基板; 第一绝缘层，设置在所述基板上，并且在与所述基板中的所述孔对应的位置处具有第一纳米孔; 设置在第一绝缘层上的第一和第二电极，其中第一和第二电极彼此间隔开，第一纳米孔位于它们之间; 设置在所述第一电极的至少一部分上的第一电极焊盘; 设置在所述第二电极的至少一部分上的第二电极焊盘; 以及设置在所述第一和第二电极焊盘的至少一部分上的保护层; 以及其制造方法。

7. 发明申请

US20110304849A1 DEVICE FOR CALIBRATING OPTICAL SCANNER, METHOD OF MANUFACTURING THE DEVICE, AND METHOD OF CALIBRATING OPTICAL SCANNER USING THE DEVICE 审中-公开
标题翻译：用于校准光学扫描仪的装置，制造装置的方法以及使用装置校准光学扫描仪的方法
公开(公告)号：US20110304849A1
公开(公告)日：2011-12-15
申请号：US12915486
申请日：2010-10-29
申请人： Sung-min CHI , Sung-ouk JUNG , Myoung-soon KIM , Jeo-young SHIM , Tae-han JEON
发明人： Sung-min CHI , Sung-ouk JUNG , Myoung-soon KIM , Jeo-young SHIM , Tae-han JEON
IPC分类号： G01J1/10 , G03F7/20 , G03F7/004
CPC分类号： G01N21/6452
摘要： A device for calibrating an optical scanner includes a substrate; and a pattern disposed on the substrate, the pattern comprising a photoresist.
摘要翻译：用于校准光学扫描仪的装置包括：基板; 以及设置在所述基板上的图案，所述图案包括光致抗蚀剂。

8. 发明申请

US20120078527A1 KIT AND METHOD FOR PREDICTING SENSITIVITY OF GASTRIC CANCER PATIENT TO ANTI-CANCER AGENT 审中-公开
标题翻译：用于预防胃癌患者对抗癌剂敏感性的试剂盒和方法
公开(公告)号：US20120078527A1
公开(公告)日：2012-03-29
申请号：US13244095
申请日：2011-09-23
申请人： Chang-eun YOO , Tae-jin AHN , Kyu-sang LEE , Jeo-young SHIM , Ki-eun KIM , Myoung-soon KIM , Sung-woo HONG , Tae-han JEON , Jhin-gook KIM , Se-hoon PARK , In-suk SOHN , Sin-ho JUNG
发明人： Chang-eun YOO , Tae-jin AHN , Kyu-sang LEE , Jeo-young SHIM , Ki-eun KIM , Myoung-soon KIM , Sung-woo HONG , Tae-han JEON , Jhin-gook KIM , Se-hoon PARK , In-suk SOHN , Sin-ho JUNG
IPC分类号： G06F19/00 , C12Q1/68 , C40B30/04
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/156
摘要： A kit and method for predicting the sensitivity of gastric cancer patient to an anti-cancer agent are disclosed.
摘要翻译：公开了一种用于预测胃癌患者对抗癌剂敏感性的试剂盒和方法。

9. 发明申请

US20120326732A1 NANOSENSOR AND METHOD OF DETECTING TARGET MOLECULE BY USING THE SAME 审中-公开
标题翻译：用它们检测目标分子的纳米传感器和方法
公开(公告)号：US20120326732A1
公开(公告)日：2012-12-27
申请号：US13475643
申请日：2012-05-18
申请人： Seong-ho CHO , Dong-ho LEE , Jeo-young SHIM
发明人： Seong-ho CHO , Dong-ho LEE , Jeo-young SHIM
IPC分类号： G01N27/04 , G01N27/02 , G01N27/22
CPC分类号： G01N33/48721 , B82Y15/00
摘要： The present disclosure includes a sensor and method for detecting a target molecule. In one instance, a sensor comprises a substrate including a hole, a first insulating layer located on the substrate and including a first nanopore corresponding to the hole, a first electrode, a second electrode, wherein the first electrode and the second electrode are located on a surface of the first insulating layer and are spaced apart by the first nanopore forming a nanogap, and a modulation unit configured to apply a unit input signal between the first electrode and the second electrode, wherein at least one unit input signal is applied as a target molecule passes through the nanogap.
摘要翻译：本公开内容包括用于检测靶分子的传感器和方法。在一种情况下，传感器包括基板，其包括孔，位于基板上的第一绝缘层，并且包括对应于该孔的第一纳米孔，第一电极，第二电极，其中第一电极和第二电极位于第一绝缘层的表面并且由形成纳米隙的第一纳米孔间隔开;以及调制单元，被配置为在第一电极和第二电极之间施加单位输入信号，其中至少一个单位输入信号作为靶分子通过纳米隙。

10. 发明申请

US20120146162A1 NANOSENSOR AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：纳米传感器及其制造方法
公开(公告)号：US20120146162A1
公开(公告)日：2012-06-14
申请号：US13323417
申请日：2011-12-12
申请人： Seong-ho CHO , Dong-ho LEE , Jeo-young SHIM
发明人： Seong-ho CHO , Dong-ho LEE , Jeo-young SHIM
IPC分类号： H01L29/66 , H01L21/02 , B82Y15/00 , B82Y40/00
CPC分类号： B82Y15/00 , B82Y40/00
摘要： A nanosensor comprising a substrate in which an opening defining a hole is formed; a first layer disposed on the substrate, which comprises a first nanopore in communication with the hole in the substrate; and a second layer contacted or coupled with the first layer and formed of a porous material.
摘要翻译：一种纳米传感器，包括其中形成有限定孔的开口的基板; 设置在所述基板上的第一层，其包括与所述基板中的所述孔连通的第一纳米孔; 并且第二层与第一层接触或耦合并由多孔材料形成。

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