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    • 1. 发明授权
    • .omega.-(N-acylamino)alkylphosphoryl ethanolamines, pharmaceutical
compositions containing them, and their uses
    • {107-(N-酰基氨基)烷基磷酰基乙醇胺,含有它们的药物组合物及其用途
    • US3985875A
    • 1976-10-12
    • US537601
    • 1974-12-30
    • Kouji HayashiMasahisa HashimotoKiyoshi NakamuraMasanao ShimizuNaonobu HatanoKunihiko Takeyama
    • Kouji HayashiMasahisa HashimotoKiyoshi NakamuraMasanao ShimizuNaonobu HatanoKunihiko Takeyama
    • C07F9/09A01N9/36
    • C07F9/091Y02P20/55Y10S530/86
    • New .omega.-(N-acylamino)alkylphosphoryl ethanolamines and their pharmaceutically acceptable acid addition salts have superior renin-inhibitory activities, antihypertensive activities and cholesterol-lowering activities. The .omega.-(N-acylamino)alkylphosphoryl ethanolamines are prepared by (1) reacting an .omega.-(N-acylamino) alkanol with a 2-(N-substituted amino)ethyl phosphate or its derivative, hydrolyzing the resulting product or splitting off the phosphoric acid-protective group of the resulting product thereby to form an .omega.-(N-acylamino) alkyl 2-(N-substituted amino) ethyl phosphate, and splitting off the amino-protective groups of the resulting phosphate, or (2) reacting an .omega.-(N-acylamino) alkanol with a phosphorus oxyhalide, reacting the resulting .omega.-(N-acylamino)alkyl dichlorophosphate with a 2-(N-substituted amino) ethanol, hydrolyzing the reaction product to form an .omega.-(N-acylamino) alkyl 2-(N-substituted)ethyl phosphate, and splitting off the amino-protective groups of said phosphate.
    • 新的ω-(N-酰基氨基)烷基磷酰基乙醇胺及其药学上可接受的酸加成盐具有优异的肾素抑制活性,降压活性和降胆固醇活性。 ω-(N-酰氨基)烷基磷酰基乙醇胺通过以下步骤制备:(1)使ω-(N-酰氨基)链烷醇与2-(N-取代氨基)乙基磷酸酯或其衍生物反应,水解得到的产物或将 得到产物的磷酸保护基,从而形成2-(N-取代氨基)乙基磷酸的ω-(N-酰基氨基)烷基酯,并分离得到的磷酸酯的氨基保护基,或(2)使 将具有卤代磷酸酯的ω-(N-酰基氨基)链烷醇与所得的ω-(N-酰基氨基)烷基二氯磷酸酯与2-(N-取代的氨基)乙醇反应,水解反应产物以形成ω-(N- 酰基氨基)烷基2-(N-取代)乙基磷酸酯,并分离出所述磷酸酯的氨基保护基团。
    • 4. 发明申请
    • ANTENNA DEVICE AND ELECTRONIC APPARATUS INCLUDING ANTENNA DEVICE
    • 天线装置和包括天线装置的电子装置
    • US20130050057A1
    • 2013-02-28
    • US13533770
    • 2012-06-26
    • Kouji HayashiKoichi SatoNatsumi Endo
    • Kouji HayashiKoichi SatoNatsumi Endo
    • H01Q21/28
    • H01Q21/28H01Q1/38H01Q1/48H01Q1/521
    • According to one embodiment, an antenna device according to this embodiment includes first and second feed terminals. The distance between the first and second feed terminals is set to a distance less than or equal to almost one quarter a wavelength corresponding to a predetermined resonant frequency. A first end of the first antenna including a first band, as a communication band, including the resonant frequency is connected to the first feed terminal. A first end of the second antenna including a second band, as a communication band, including at least the resonant frequency of the first antenna is connected to the second feed terminal. A first protruding portion is provided between the first and second antennas so as to protrude from a ground pattern of an antenna board.
    • 根据一个实施例,根据该实施例的天线装置包括第一和第二馈电端子。 第一和第二馈电端子之间的距离被设置为小于或等于对应于预定谐振频率的波长的几乎四分之一的距离。 包括具有共振频率的作为通信频带的第一频带的第一天线的第一端连接到第一馈送终端。 第二天线的包括至少包括第一天线的谐振频率的通信频带的第二频带的第一端连接到第二馈送终端。 第一突出部分设置在第一和第二天线之间,以便从天线板的接地图案突出。