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    • 5. 发明申请
    • Rheumatoid Arthritis Test Method and Treating Method
    • 类风湿关节炎测试方法及治疗方法
    • US20090176245A1
    • 2009-07-09
    • US12281191
    • 2007-03-01
    • Masahiko SuzukiFumie AosaiKoichi Ueno
    • Masahiko SuzukiFumie AosaiKoichi Ueno
    • G01N33/53
    • G01N33/564C07K16/18G01N2800/102G01N2800/52G01N2800/56
    • It is intended to evaluate the prognosis of rheumatoid arthritis based on the evaluation of the disease severity of the patient to select a treatment method suitable for each rheumatoid arthritis patients, and to measure HSC71 protein levels of the patients before and after the administrations of therapeutic agents to determine the efficacy of various therapeutic agents for each of rheumatoid arthritis patients, and to use thereof as a remedy for preventing onset and progression of rheumatoid arthritis. It has been revealed that whether HSC71 (heat shock cognate protein 71), which is a member of the heat shock protein 70 family, shows any difference in expression between rheumatoid arthritis patients and healthy subjects. In the case where the HSC71 protein is accelerated in a rheumatoid arthritis patient the HSC71 concentrations in the serum, synovial fluid, serebrospinal fluid, urine, saliva and sputum of the patient are measured to thereby examine the disease severity of rheumatoid arthritis. Based thereon, the prognosis of the rheumatoid arthritis is evaluated and a method suitable for the patient is selected. HSC71 protein levels are measured before and after the administration of therapeutic agents to a rheumatoid arthritis patient and the efficacy of the therapeutic agents are determined. Further, Use as a remedy or preventing the onset and progression of rheumatoid arthritis is intended.
    • 旨在通过评估患者的疾病严重程度来评估类风湿性关节炎的预后,以选择适合于每种类风湿性关节炎患者的治疗方法,并测量治疗剂施用前后患者的HSC71蛋白水平 以确定各种治疗剂对于类风湿关节炎患者的功效,并将其用作预防类风湿性关节炎发病和进展的补救措施。 已经显示,作为热休克蛋白70家族的成员的HSC71(热休克同源蛋白71)是否表现出类风湿性关节炎患者和健康受试者之间的表达的任何差异。 在HSC71蛋白在类风湿关节炎患者中加速的情况下,测量患者血清,滑液,脊髓液,尿液,唾液和痰中的HSC71浓度,从而检测类风湿性关节炎的疾病严重程度。 基于此,评估类风湿性关节炎的预后,并选择适合于患者的方法。 在向类风湿性关节炎患者施用治疗剂之前和之后测量HSC71蛋白水平,并测定治疗剂的功效。 此外,意图是用作补救剂或预防类风湿性关节炎的发作和进展。
    • 8. 发明授权
    • Storage system that transfers system information elements
    • 传输系统信息元素的存储系统
    • US08326939B2
    • 2012-12-04
    • US12068088
    • 2008-02-01
    • Koichi UenoKoji NagataYusuke Nonaka
    • Koichi UenoKoji NagataYusuke Nonaka
    • G06F15/16
    • G06F3/0647G06F3/0604G06F3/067G06F11/2092
    • A first storage system that has a first storage device comprises a first interface device that is connected to a second interface device that a second storage system has. A first controller of the first storage system reads system information elements of first system information (information relating to the constitution and control of the first storage system) from a first system area (a storage area that is not provided for the host of the first storage device) and transfers the system information elements or modified system information elements to the second storage system via the first interface device. The system information elements are recorded in a second system area in a second storage device that the second storage system has.
    • 具有第一存储设备的第一存储系统包括连接到第二存储系统具有的第二接口设备的第一接口设备。 第一存储系统的第一控制器从第一系统区域(不为第一存储器的主机提供的存储区域)读取第一系统信息的系统信息(与第一存储系统的结构和控制有关的信息) 设备),并且经由第一接口设备将系统信息元素或修改的系统信息元素传送到第二存储系统。 系统信息元素被记录在第二存储系统所具有的第二存储装置中的第二系统区域中。