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1. 发明申请

US20060241499A1 Multifunctional fluorescence diagnosis system 有权
标题翻译：多功能荧光诊断系统
公开(公告)号：US20060241499A1
公开(公告)日：2006-10-26
申请号：US11361484
申请日：2006-02-24
申请人： Klaus Irion , Andre Ehrhardt , Reinhold Baumgartner , Herbert Stepp , Thomas Pongratz
发明人： Klaus Irion , Andre Ehrhardt , Reinhold Baumgartner , Herbert Stepp , Thomas Pongratz
IPC分类号： A61B6/00
CPC分类号： A61B5/413 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B1/307 , A61B5/0071 , A61B5/0084 , A61B5/721 , G01N21/6428 , G01N21/6456
摘要： A fluorescence diagnosis system has a viewing system at least one light source and a camera system. The at least one light source can be operated in three modes, a first generating white light, a second with a first fluorescence excitation light of a first excitation wavelength and a third in which a second fluorescence excitation light of a second excitation wavelength is generated producing a fluorescence image in the NIR range. The camera system is sensitive at least in the visible and the NIR range. The system further comprises an image processing system for converting the fluorescence image in the NIR range into a visible image.
摘要翻译：荧光诊断系统具有至少一个光源和相机系统的观察系统。所述至少一个光源可以以三种模式操作，第一产生白光，第二产生具有第一激发波长的第一荧光激发光，其中第三激发光产生第二激发波长的第二荧光激发光，产生产生 NIR范围内的荧光图像。至少在可见光和近红外范围内，相机系统是敏感的。该系统还包括用于将NIR范围内的荧光图像转换成可见图像的图像处理系统。

2. 发明申请

US20070053204A1 Confocal microendoscope comprising optical fibres with a tapering diameter 审中-公开
标题翻译：共焦显微镜，包括具有锥形直径的光纤
公开(公告)号：US20070053204A1
公开(公告)日：2007-03-08
申请号：US10573141
申请日：2004-09-10
申请人： Ingo Krohne , Andre Ehrhardt , Klaus Irion , Herbert Stepp
发明人： Ingo Krohne , Andre Ehrhardt , Klaus Irion , Herbert Stepp
IPC分类号： A61B3/00 , A61B1/06 , G03B29/00 , G03B15/02 , G02B6/06 , F21V5/00
CPC分类号： A61B5/0068 , A61B5/0084 , G02B21/0028 , G02B23/2461
摘要： The invention relates to a confocal microendoscope, in which the diameter of optical fibres at the proximal end (8) of an optical fibre bundle (9) is greater than at the distal end (15). This permits the efficiency of coupling the light of a light source to be increased, without reducing the resolution of the microendoscope. In addition, the proximal ends (8) of the optical fibres (10) are arranged in a grid, for example, by means of a fibre receiving unit (11) that holds the individual optical fibres. A microlens unit (13) can also be provided, said unit allocating a microlens (14) to each optical fibre end.
摘要翻译：本发明涉及一种共焦显微镜，其中光纤束（9）的近端（8）处的光纤的直径大于远端（15）处的光纤直径。这允许在不降低微内镜的分辨率的情况下增加耦合光源的光的效率。此外，光纤（10）的近端（8）例如通过保持各个光纤的光纤接收单元（11）布置成格栅。还可以设置微透镜单元（13），所述单元向每个光纤端分配微透镜（14）。

3. 发明授权

US06212425B1 Apparatus for photodynamic diagnosis 有权
标题翻译：光动力诊断装置
公开(公告)号：US06212425B1
公开(公告)日：2001-04-03
申请号：US09043850
申请日：1998-09-18
申请人： Klaus Irion , Reinhold Baumgartner , Herbert Stepp , André Ehrhardt , Karlheinz Strobl
发明人： Klaus Irion , Reinhold Baumgartner , Herbert Stepp , André Ehrhardt , Karlheinz Strobl
IPC分类号： A61B500
CPC分类号： G01N21/6486 , A61B1/00186 , A61B1/043 , A61B1/055 , A61B1/0638 , A61B1/0646 , A61B5/0071 , A61B5/0084 , G01N21/6456
摘要： A device for “in vivo” diagnosis by means of a photosensibilisator light-induced reaction or a reaction caused by intrinsic fluorescence in biological tissue, having an illumination system, which is provided with at least one light source having a lamp system which generates incoherent light in a wavelength range of at least 380 to 680 nm, a light delivering unit which directs the light of said illumination system at the therapy and/or to-be-diagnosed tissue area, and an imaging, image-recording and image-transmitting unit which images the light coming from said tissue area in a proximal image plane. The device is distinguished in that the net spectral transmittance in the light delivering unit and in the image-generating unit of the device are selected in such a manner that, on the one hand, practically no light with a wavelength of &lgr; from the range utilized for excitation, which by nature has relatively high intensity, “reaches” via the image-generating unit of the device into the proximal image plane, whereas light with a wavelength of &lgr; from the range in which fluorescence occurs can reach the proximal image plane only if it comes from the illuminated tissue are and not from the illumination system.
摘要翻译：一种用于通过光敏效应器光诱导反应或由生物组织中的固有荧光引起的反应进行的“体内”诊断的装置，具有照明系统，其具有至少一个具有产生不相干光的灯系统的光源在至少380至680nm的波长范围内，将所述照明系统的光引导到治疗和/或待诊断的组织区域的光输送单元，以及成像，图像记录和图像发送单元其在近端图像平面中对来自所述组织区域的光进行成像。该装置的特征在于，以这样的方式选择装置中的光输送单元和图像生成单元中的净光谱透射率，一方面实际上不具有从所使用的范围的羔羊波长的光对于本质上具有相对高强度的激发，通过装置的图像生成单元“到达”到近端图像平面中，而从发生荧光的范围的波长为lamb的光可以仅到达近端图像平面如果它来自照明组织而不是来自照明系统。

4. 发明申请

US20060268552A1 Light source for endoscopy or microscopy 有权
标题翻译：内窥镜或显微镜的光源
公开(公告)号：US20060268552A1
公开(公告)日：2006-11-30
申请号：US11442579
申请日：2006-05-26
申请人： Klaus Irion , Andre Ehrhardt , Markus Simmen
发明人： Klaus Irion , Andre Ehrhardt , Markus Simmen
IPC分类号： F21V29/00
CPC分类号： F21V29/51 , A61B1/0669 , A61B1/12 , F21V29/67 , F21V29/717 , F21V29/763 , F21V29/83 , F21V29/89 , F28D15/0275
摘要： A light source for endoscopy or microscopy comprises a lamp, a heat sink, the heat sink being thermally connected to the lamp and at least one heat pipe, which is thermally connected to the heat sink and which dissipates the heat that is generated by the lamp and transferred to the heat sink.
摘要翻译：用于内窥镜检查或显微镜的光源包括灯，散热器，散热器热连接到灯和至少一个热管，其热连接到散热器并且散发由灯产生的热量并转移到散热器。

5. 发明申请

US20060256544A1 Light system for photodynamic diagnosis and/or therapy 失效
标题翻译：用于光动力学诊断和/或治疗的光系统
公开(公告)号：US20060256544A1
公开(公告)日：2006-11-16
申请号：US11432014
申请日：2006-05-11
申请人： Klaus Irion , Andre Ehrhardt , Andreas Schmal
发明人： Klaus Irion , Andre Ehrhardt , Andreas Schmal
IPC分类号： G03B15/02
CPC分类号： G02B6/4298 , A61B5/0059 , A61N5/0601 , A61N5/062 , G02B6/4225 , G02B6/4226
摘要： A light system for medical photodynamic applications comprises an incoherent light source emitting a light with a power and a light guide which has a distal end and an entrance interface. The entrance interface and the light source have a position relative to one another and are able to be positioned relative to one another. The light system further comprises a luminous power meter for measuring a luminous power emitted at the distal end of the light guide, a motorized positioning unit for positioning the entrance interface and the light source relative to one another, and a control unit which controls the positioning unit as a function of the luminous power measured by the luminous power meter.
摘要翻译：用于医疗光动力学应用的光系统包括发射具有光焦度的光和具有远端和入射界面的光导的非相干光源。入口接口和光源具有相对于彼此的位置，并且能够相对于彼此定位。光系统还包括用于测量在光导的远端发射的发光功率的光功率计，用于相对于彼此定位入口界面和光源的电动定位单元，以及控制单元，其控制定位单位作为由发光度计测量的发光功率的函数。

6. 发明授权

US06361490B1 Testing and/or setting device for a photodynamic diagnosis or therapy system, or for training on such a system 有权
标题翻译：用于光动力学诊断或治疗系统的测试和/或设置装置，或用于在这种系统上的训练
公开(公告)号：US06361490B1
公开(公告)日：2002-03-26
申请号：US09254984
申请日：1999-03-17
申请人： Klaus Irion , Andre Ehrhardt , Clemens Rebholz , Karl-Heinz Strobl
发明人： Klaus Irion , Andre Ehrhardt , Clemens Rebholz , Karl-Heinz Strobl
IPC分类号： A61B100
CPC分类号： A61N5/0601 , A61B5/0059 , A61B5/1495 , A61B2560/0233 , A61N5/062 , A61N2005/0652
摘要： A device for testing and/or adjusting a PDD or PDT system and/or for training on such a system comprises an illumination system emitting light which serves at least to stimulate a fluorescent dye and which may be directed to this end onto a tissue zone to be diagnosed and/or therapeutically treated, and an imaging unit which images the light arriving from the stimulated tissue zone. The invention is characterized by the provisions that a target is provided which reflects the light of the illumination system, and that the target comprises at least one light source which emits light within the wavelength range of the fluorescence spectrum of the dye.
摘要翻译：用于测试和/或调整PDD或PDT系统和/或用于在这种系统上进行训练的装置包括发射光的照明系统，其至少用于刺激荧光染料，并且可以将其引导到组织区域被诊断和/或治疗处理，以及成像单元，其对从受刺激的组织区域到达的光进行成像。本发明的特征在于提供了一种反射照明系统的光的目标，并且目标包括在染料的荧光光谱的波长范围内发射光的至少一个光源。

7. 发明申请

US20070060792A1 Method and apparatus for generating at least one section of a virtual 3D model of a body interior 有权
标题翻译：用于产生身体内部的虚拟3D模型的至少一个部分的方法和装置
公开(公告)号：US20070060792A1
公开(公告)日：2007-03-15
申请号：US11503196
申请日：2006-08-11
申请人： Wolfgang Draxinger , Margarita Noll , Herbert Stepp , Klaus Irion
发明人： Wolfgang Draxinger , Margarita Noll , Herbert Stepp , Klaus Irion
IPC分类号： A61B1/00
CPC分类号： A61B5/1077 , A61B1/00009 , A61B1/042 , A61B5/065 , A61B8/12 , A61B34/20 , A61B90/361 , A61B2034/105 , A61B2034/2048 , A61B2034/2051
摘要： A method for generating at least one section of a virtual 3D model of a body interior, in particular a hollow organ, uses data that are provided by at least one endoscope introduced into the body interior. The data comprise at least one position and orientation of the endoscope, the at least one position and orientation being as signed at least one distance between the endoscope and the at least one point on a surface of the body interior, and at least one endoscopic image of the surface of the body interior in the region of the at least one point on the surface of the body interior. From the said data relating to a number of different positions and orientations of the endoscope is/are generated the section or sections of the 3D model in superposition with the associated endoscopic image. An appropriate apparatus is also described.
摘要翻译：用于产生身体内部，特别是中空器官的虚拟3D模型的至少一个部分的方法使用由引入到身体内部的至少一个内窥镜提供的数据。所述数据包括所述内窥镜的至少一个位置和取向，所述至少一个位置和取向在所述内窥镜与所述主体内部的表面上的所述至少一个点之间具有至少一个距离，并且至少一个内窥镜图像在身体内表面上的至少一个点的区域中的身体内部的表面。从与所述内窥镜的多个不同位置和取向相关的所述数据生成与相关联的内窥镜图像重叠的3D模型的部分或部分。还描述了适当的装置。

8. 发明申请

US20060073458A1 Virtual OP simulator 有权
标题翻译：虚拟OP模拟器
公开(公告)号：US20060073458A1
公开(公告)日：2006-04-06
申请号：US11232359
申请日：2005-09-21
申请人： Andre Ehrhardt , Klaus Irion , Bjoern Speiser
发明人： Andre Ehrhardt , Klaus Irion , Bjoern Speiser
IPC分类号： G09B23/28
CPC分类号： G09B23/285
摘要： The invention relates to a virtual OP simulator (10) for training for minimal-invasive operations, in particular for endourological interventions, having a simulation calculator unit (12), at least one instrument (40), at least one instrument input unit (30) for picking up the instrument (40), with the instrument input unit (30) allowing and recording movement of the instrument (40) in a predetermined number of degrees of freedom, and a force feedback unit (60) which is associated with the instrument input unit (30) and applies variable forces to the instrument (40) directly or indirectly via the instrument input unit (30). A monitoring control unit (20) is provided, which is connected to the simulation computer unit (12) and to the instrument input unit (30), with the monitoring control unit (20) having a first interface (24) which provides communication of parameters between the monitoring control unit (20) and the simulation computer unit (12) at a speed in the region of the video framing rate, and having a second interface (26) which provides communication of parameters with the instrument input unit (30) at a speed which is higher than, in particular a multiple of, the video framing rate, and with the instrument input unit (30) allowing at least four degrees of freedom, detecting movements of the instrument (40) within these degrees of freedom, supplying corresponding signals to the monitoring control unit (20) and receiving signals for the force feedback unit (60), at least some of which are generated by the simulation computer unit (12).
摘要翻译：本发明涉及一种用于训练最小侵入性操作的虚拟OP模拟器（10），特别是用于内科学干预，具有模拟计算器单元（12），至少一个仪器（40），至少一个仪器输入单元（30）），用于拾取所述仪器（40），所述仪器输入单元（30）允许和记录所述仪器（40）以预定数量的自由度的运动;以及力反馈单元（60），所述力反馈单元仪器输入单元（30），并通过仪器输入单元（30）直接或间接地向仪器（40）施加可变力。提供了一个监视控制单元（20），其连接到模拟计算机单元（12）和仪器输入单元（30），监视控制单元（20）具有第一接口（24）监视控制单元（20）和模拟计算机单元（12）之间的参数以视频成帧速率区域的速度，并且具有提供与仪器输入单元（30）的参数通信的第二接口（26）以高于视频成帧速率的速度，并且通过允许至少四个自由度的仪器输入单元（30）检测仪器（40）在这些自由度内的运动，向所述监视控制单元（20）提供相应的信号并且接收所述力反馈单元（60）的信号，所述力反馈单元（60）中的至少一些由所述模拟计算机单元（12）产生。

9. 发明申请

US20060004260A1 Endotracheal video device 审中-公开
标题翻译：气管内视频装置
公开(公告)号：US20060004260A1
公开(公告)日：2006-01-05
申请号：US11174052
申请日：2005-07-01
申请人： Ben Boedeker , George Berci , Marshal Kaplan , James Barry , David Chatenever , Klaus Irion , Andre Ehrhardt , Jurgen Rudischhauser , Daniel Mattsson-Boze
发明人： Ben Boedeker , George Berci , Marshal Kaplan , James Barry , David Chatenever , Klaus Irion , Andre Ehrhardt , Jurgen Rudischhauser , Daniel Mattsson-Boze
IPC分类号： A61B1/267
CPC分类号： A61M16/0488 , A61B1/00165 , A61B1/042 , A61B1/07 , A61B1/267 , A61M16/04 , A61M16/0409
摘要： An endotracheal device for use with a supra-laryngeal mask including a video display for providing images of the area ahead of the endotracheal device to facilitate insertion without damaging the surrounding tissue; the endotracheal device having a flexible portion and a rigid portion maintaining a light and an image guide for transmitting illuminating light ahead of the endotracheal device and for transmitting reflected light from the area ahead of the endotracheal device.
摘要翻译：一种用于上喉罩的气管内装置，包括用于提供气管内装置前方区域的图像的视频显示器，以便于插入而不损伤周围组织; 所述气管内装置具有柔性部分和保持光的刚性部分和用于在气管内装置之前传输照明光的图像引导件，并用于从气管插管装置前方的区域传送反射光。

10. 发明申请

US20050192481A1 Laryngoscope and camera coupling 审中-公开
标题翻译：喉镜和相机联轴器
公开(公告)号：US20050192481A1
公开(公告)日：2005-09-01
申请号：US11062131
申请日：2005-02-18
申请人： George Berci , Marshal Kaplan , James Barry , David Chatenever , Klaus Irion , Andre Ehrhardt , Jurgen Rudischhauser , Daniel Mattsson-Boze
发明人： George Berci , Marshal Kaplan , James Barry , David Chatenever , Klaus Irion , Andre Ehrhardt , Jurgen Rudischhauser , Daniel Mattsson-Boze
IPC分类号： A61B1/267
CPC分类号： A61B1/267 , A61B1/00165 , A61B1/07
摘要： A laryngoscope with a detachable camera, the system providing illuminating light to and images of the area ahead of the laryngoscope to facilitate insertion of the laryngoscope without damage to the surrounding tissue, the system including a keyed attaching device for facilitating attachment of camera and laryngoscope in a correct orientation.
摘要翻译：具有可拆卸照相机的喉镜，该系统向喉镜前方提供照明光和图像，以便于插入喉镜而不损伤周围组织，该系统包括用于便于将照相机和喉镜连接在一起的带键的附接装置正确的方向。

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