专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08886310B2 System and method for controlling a heart stimulator 有权
标题翻译：用于控制心脏刺激器的系统和方法
公开(公告)号：US08886310B2
公开(公告)日：2014-11-11
申请号：US12303987
申请日：2006-06-09
申请人： Kjell Norén , Taraneh G. Farazi
发明人： Kjell Norén , Taraneh G. Farazi
IPC分类号： A61N1/00 , A61N1/365 , A61B5/024 , A61N1/36 , A61N1/362 , A61B5/00
CPC分类号： A61N1/365 , A61B5/02405 , A61B5/4035 , A61N1/36114 , A61N1/3622
摘要： In a system and method for controlling an implantable stimulator capable of producing pacing pulses to be delivered to cardiac tissue, as well as vagal stimulation pulses to be delivered to vagus nerve sites, upon detection of a premature cardiac event, such as a premature ventricular or atrial contraction, a simulated heart rate turbulence (HRT) procedure is applied if the intrinsic heart rate turbulence is weakened or absent. The simulated HRT includes a first phase in which the heart rate is increased, from the existing level, for a number of heart beats, a second phase in which the heart rate is decreased for a number of heart beats, and an optional third phase in which the heart rate is returned to said existing level.
摘要翻译：在一种用于控制可植入式刺激器的系统和方法中，所述系统和方法能够产生起搏脉冲以被传送到心脏组织，以及迷走神经刺激脉冲，以便在检测到过早心脏事件（例如心室早搏如果内在心率湍流减弱或不存在，则应用心房收缩模拟心率湍流（HRT）程序。模拟HRT包括第一阶段，其中心率从现有水平增加，对于多个心跳，第二阶段，其中多个心脏搏动的心率降低;以及可选择的第三阶段心率恢复到现有水平。

2. 发明申请

US20100010555A1 SYSTEM AND METHOD FOR CONTROLLING A HEART STIMULATOR 有权
标题翻译：用于控制心脏刺激器的系统和方法
公开(公告)号：US20100010555A1
公开(公告)日：2010-01-14
申请号：US12303987
申请日：2006-06-09
申请人： Kjell Norén , Taraneh G. Farazi
发明人： Kjell Norén , Taraneh G. Farazi
IPC分类号： A61N1/365
CPC分类号： A61N1/365 , A61B5/02405 , A61B5/4035 , A61N1/36114 , A61N1/3622
摘要： In a system and method for controlling an implantable stimulator capable of producing pacing pulses to be delivered to cardiac tissue, as well as vagal stimulation pulses to be delivered to vagus nerve sites, upon detection of a premature cardiac event, such as a premature ventricular or atrial contraction, a simulated heart rate turbulence (HRT) procedure is applied if the intrinsic heart rate turbulence is weakened or absent. The simulated HRT includes a first phase in which the heart rate is increased, from the existing level, for a number of heart beats, a second phase in which the heart rate is decreased for a number of heart beats, and an optional third phase in which the heart rate is returned to said existing level.
摘要翻译：在一种用于控制可植入式刺激器的系统和方法中，所述系统和方法能够产生起搏脉冲以被传送到心脏组织，以及迷走神经刺激脉冲，以便在检测到过早心脏事件（例如心室早搏如果内在心率湍流减弱或不存在，则应用心房收缩模拟心率湍流（HRT）程序。模拟HRT包括第一阶段，其中心率从现有水平增加，对于多个心跳，第二阶段，其中多个心脏搏动的心率降低;以及可选择的第三阶段心率恢复到现有水平。

3. 发明授权

US08571642B2 Pre-ejection interval (PEI) monitoring devices, systems and methods 有权
标题翻译：预喷射间隔（PEI）监测装置，系统和方法
公开(公告)号：US08571642B2
公开(公告)日：2013-10-29
申请号：US12882084
申请日：2010-09-14
申请人： Jong Gill , Brian Jeffrey Wenzel , Allen Keel , Wenbo Hou , Edward Karst , Taraneh G. Farazi
发明人： Jong Gill , Brian Jeffrey Wenzel , Allen Keel , Wenbo Hou , Edward Karst , Taraneh G. Farazi
IPC分类号： A61B5/02
CPC分类号： A61B5/0456 , A61B5/02028 , A61B5/0295 , A61B5/0422 , A61B5/686 , A61B5/7239 , A61N1/3684
摘要： Provided herein are implantable systems, and methods for use therewith, for monitoring a patient's pre-ejection interval (PEI). A signal indicative of cardiac electrical activity and a signal indicative of changes in arterial blood volume are obtained. One or more predetermined features of the signal indicative of cardiac electrical activity and the signal indicative of changes in arterial blood volume are detected. The patient's PEI is determined by determining an interval between the predetermined feature of the signal indicative of cardiac electrical activity and the predetermined feature of the signal indicative of changes in arterial blood volume.
摘要翻译：本文提供了可植入系统及其使用的方法，用于监测患者的预喷射间隔（PEI）。获得指示心脏电活动的信号和指示动脉血容量变化的信号。检测到指示心脏电活动的信号的一个或多个预定特征以及指示动脉血容量变化的信号。通过确定指示心脏电活动的信号的预定特征与指示动脉血容量变化的信号的预定特征之间的间隔来确定患者的PEI。

4. 发明授权

US08989852B2 Systems and methods for use by implantable medical devices for detecting and discriminating stroke and cardiac ischemia using electrocardiac signals 有权
标题翻译：使用可植入医疗器械用于使用心电信号检测和鉴别中风和心脏缺血的系统和方法
公开(公告)号：US08989852B2
公开(公告)日：2015-03-24
申请号：US13207307
申请日：2011-08-10
申请人： Jong Gill , Rupinder Bharmi , Edward Karst , Ryan Rooke , Riddhi Shah , Fujian Qu , Gene A. Bornzin , Taraneh G. Farazi , Euljoon Park
发明人： Jong Gill , Rupinder Bharmi , Edward Karst , Ryan Rooke , Riddhi Shah , Fujian Qu , Gene A. Bornzin , Taraneh G. Farazi , Euljoon Park
IPC分类号： A61B5/0452 , A61B5/0468 , A61B5/00 , A61B5/0205 , A61B5/0215 , A61B5/042 , A61N1/37 , A61B5/024 , A61B5/0295
CPC分类号： A61B5/0468 , A61B5/0031 , A61B5/0205 , A61B5/02158 , A61B5/02405 , A61B5/0295 , A61B5/0422 , A61B5/4839 , A61N1/3702
摘要： Techniques are provided for detecting and distinguishing stroke and cardiac ischemia based on electrocardiac signals. In one example, the device senses atrial and ventricular signals within the patient along a set of unipolar sensing vectors and identifies certain morphological features within the signals such as PR intervals, ST intervals, QT intervals, T-waves, etc. The device detects changes, if any, within the morphological features such as significant shifts in ST interval elevation or an inversion in T-wave shape, which are indicative of stroke or cardiac ischemia. By selectively comparing changes detected along different unipolar sensing vectors, the device distinguishes or discriminates stroke from cardiac ischemia within the patient. The discrimination may be corroborated using various physiological and hemodynamic parameters. In some examples, the device further identifies the location of the ischemia within the heart. In still other examples, the device detects cardiac ischemia occurring during stroke.
摘要翻译：提供了用于基于心电信号检测和区分中风和心脏缺血的技术。在一个示例中，该装置沿着一组单极感测向量感测患者内的心房和心室信号，并且识别信号内的某些形态特征，例如PR间隔，ST间隔，QT间隔，T波等。该装置检测变化（如果有的话）在形态学特征之中，例如ST间隔升高的显着变化或T波形的反转，其指示中风或心脏缺血。通过选择性地比较沿着不同的单极性感测向量检测的变化，该装置区分或区分患者体内的心脏缺血的中风。可以使用各种生理和血液动力学参数来确认辨别。在一些实例中，该装置还识别心脏内局部缺血的位置。在另外的例子中，该装置检测在中风期间发生的心脏缺血。

5. 发明申请

US20120065528A1 PRE-EJECTION INTERVAL (PEI) MONITORING DEVICES, SYSTEMS AND METHODS 有权
标题翻译：预引导间隔（PEI）监控设备，系统和方法
公开(公告)号：US20120065528A1
公开(公告)日：2012-03-15
申请号：US12882084
申请日：2010-09-14
申请人： Jong Gill , Brian Jeffrey Wenzel , Allen Keel , Wenbo Hou , Edward Karst , Taraneh G. Farazi
发明人： Jong Gill , Brian Jeffrey Wenzel , Allen Keel , Wenbo Hou , Edward Karst , Taraneh G. Farazi
IPC分类号： A61B5/042
CPC分类号： A61B5/0456 , A61B5/02028 , A61B5/0295 , A61B5/0422 , A61B5/686 , A61B5/7239 , A61N1/3684
摘要： Provided herein are implantable systems, and methods for use therewith, for monitoring a patient's pre-ejection interval (PEI). A signal indicative of cardiac electrical activity and a signal indicative of changes in arterial blood volume are obtained. One or more predetermined features of the signal indicative of cardiac electrical activity and the signal indicative of changes in arterial blood volume are detected. The patient's PEI is determined by determining an interval between the predetermined feature of the signal indicative of cardiac electrical activity and the predetermined feature of the signal indicative of changes in arterial blood volume.
摘要翻译：本文提供了可植入系统及其使用的方法，用于监测患者的预喷射间隔（PEI）。获得指示心脏电活动的信号和指示动脉血容量变化的信号。检测到指示心脏电活动的信号的一个或多个预定特征以及指示动脉血容量变化的信号。通过确定指示心脏电活动的信号的预定特征与指示动脉血容量变化的信号的预定特征之间的间隔来确定患者的PEI。

6. 发明申请

US20120065527A1 Methods and Systems for Monitoring Aterial Stiffness 审中-公开
标题翻译：监测动静刚度的方法和系统
公开(公告)号：US20120065527A1
公开(公告)日：2012-03-15
申请号：US12882099
申请日：2010-09-14
申请人： Jong Gill , Brian Jeffrey Wenzel , Allen Keel , Wenbo Hou , Edward Karst , Taraneh G. Farazi
发明人： Jong Gill , Brian Jeffrey Wenzel , Allen Keel , Wenbo Hou , Edward Karst , Taraneh G. Farazi
IPC分类号： A61B5/0295
CPC分类号： A61B5/02007 , A61B5/0295 , A61B5/686
摘要： Implanted systems and methods for monitoring a patient's arterial stiffness are provided. An implanted sensor is used to produce a signal indicative of changes in arterial blood volume for a plurality of beats of the patient's heart. A pulse duration metric is determined for each of a plurality of pulses of the signal, wherein each pulse of the signal corresponds to a beat of the patient's heart. Arterial stiffness is monitored based on the determined pulse duration metric for the plurality of pulses of the signal. This can include monitoring arterial stiffness based on a dispersion of the pulse duration metric and/or an average of the pulse duration metric.
摘要翻译：提供了用于监测患者动脉硬度的植入系统和方法。植入的传感器用于产生指示患者心脏的多个节拍的动脉血容量变化的信号。为信号的多个脉冲中的每一个确定脉冲持续时间度量，其中信号的每个脉冲对应于患者心脏的搏动。基于确定的信号的多个脉冲的脉冲持续时间度量监测动脉硬度。这可以包括基于脉冲持续时间度量的偏差和/或脉冲持续时间度量的平均值监视动脉硬度。

7. 发明申请

US20110066055A1 SYSTEM AND METHOD FOR USE WITH AN IMPLANTABLE MEDICAL DEVICE FOR DETECTING STROKE BASED ON PHYSIOLOGICAL AND ELECTROCARDIAC INDICES 审中-公开
标题翻译：用于基于生理和电学指标检测STR WITH的可植入医疗装置的系统和方法
公开(公告)号：US20110066055A1
公开(公告)日：2011-03-17
申请号：US12558385
申请日：2009-09-11
申请人： Rupinder Bharmi , Taraneh G. Farazi
发明人： Rupinder Bharmi , Taraneh G. Farazi
IPC分类号： A61B5/0452
CPC分类号： A61B5/0452 , A61B5/0006 , A61B5/0031 , A61B5/02028 , A61B5/0205 , A61B5/024 , A61B5/02405 , A61B5/0456 , A61B5/0472 , A61B5/4076 , A61B5/6846 , A61M5/1723 , A61M2205/054 , A61M2210/125 , A61N1/36114 , A61N1/36585
摘要： Techniques are provided for detecting stroke within a patient using an implantable medical device. In one example, various electrocardiac and physiological signals are sensed within the patient by the implantable device. The device derives a set of indices from the sensed signals based on parameters affected by stroke. Stroke is then detected within the patient based on an examination of the set of indices. Warnings can then be generated, neurostimulation delivered, pacing therapy adjusted, medications dispensed, etc., in response to the stroke. In one particular example, the set of indices includes: a heart rate variability index; a heart rate turbulence index; a baroreflex index; a QT index; a respiration index; and a circadian variability index, from which a composite stroke index is derived. Time delta indices may also be generated for each individual index, which are exploited in generating the composite stroke index.
摘要翻译：提供了使用可植入医疗装置来检测患者中的卒中的技术。在一个示例中，通过可植入装置在患者体内检测各种心电信号和生理信号。该设备根据受冲击影响的参数从感测到的信号中导出一组索引。然后根据对该组指标的检查在患者体内检测中风。然后可以产生警告，响应于中风，递送神经刺激，调节起搏治疗，药物分配等。在一个特定示例中，该组索引包括：心率变异性指数; 心率湍流指数; 压力指标; QT指数; 呼吸指数和昼夜变异指数，从中得出复合笔画指数。也可以为每个单独的索引生成时间增量指数，这些索引在生成复合笔画索引时被利用。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式