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1. 发明授权

US07456949B2 Methods and systems for laser calibration and eye tracker camera alignment 有权
标题翻译：用于激光校准和眼动仪相机对准的方法和系统
公开(公告)号：US07456949B2
公开(公告)日：2008-11-25
申请号：US11755194
申请日：2007-05-30
申请人： Seema Somani , Kingman Yee , John S. Shimmick
发明人： Seema Somani , Kingman Yee , John S. Shimmick
IPC分类号： G01J1/10
CPC分类号： A61F9/00814 , A61B2017/00725 , A61F9/008 , A61F9/00802 , A61F2009/00846 , A61F2009/00855 , A61F2009/00872 , A61F2009/00897 , B23K26/705 , G01J1/4257 , G01J2001/4261 , G01N21/6456
摘要： The present invention provides methods, systems, and apparatus for calibrating a laser ablation system, such as an excimer laser system for selectively ablating a cornea of a patient's eye. The invention also facilitates alignment of eye tracking cameras that measure a position of the eye during laser eye surgery. A calibration and alignment fixture for a scanning laser beam delivery system having eye tracking cameras may include a structure positionable in a treatment plane. The structure having a feature directing laser energy incident thereon to a calibration energy sensor, at least one reference-edge to determine a characteristic of the laser beam (shape, dimensions, etc.), and an artificial pupil to determine alignment of the eye tracking cameras with the laser system.
摘要翻译：本发明提供了用于校准激光消融系统的方法，系统和装置，例如用于选择性地烧蚀患者眼睛的角膜的准分子激光系统。本发明还有助于在激光眼睛手术期间测量眼睛位置的眼睛跟踪相机的对准。用于具有眼睛跟踪摄像机的扫描激光束传送系统的校准和对准夹具可以包括可在治疗平面中定位的结构。具有将激光能量入射到校准能量传感器的特征的结构，至少一个参考边缘以确定激光束的特性（形状，尺寸等）以及用于确定眼睛跟踪的对准的人造瞳孔相机与激光系统。

2. 发明授权

US07355695B2 Wavefront calibration analyzer and methods 有权
标题翻译：波前校准分析仪及方法
公开(公告)号：US07355695B2
公开(公告)日：2008-04-08
申请号：US10799439
申请日：2004-03-12
申请人： Junzhong Liang , Dimitri Chernyak , Kingman Yee , Seema Somani , Jeffrey J. Persoff , Walter Huff , Charles Campbell , Charles R. Munnerlyn , Brian Bliven
发明人： Junzhong Liang , Dimitri Chernyak , Kingman Yee , Seema Somani , Jeffrey J. Persoff , Walter Huff , Charles Campbell , Charles R. Munnerlyn , Brian Bliven
IPC分类号： G01B11/14
CPC分类号： A61B3/1015 , A61F9/008 , A61F9/00802 , A61F2009/00848 , A61F2009/00855 , A61F2009/00872 , G01J9/00
摘要： A wavefront sensor enhances calibration of a laser ablation system, such as a laser eye surgery system, by measuring one or more characteristics of an ablated test surface. Typically, light is passed through the ablated test surface, and the light is analyzed to determine the test surface characteristics. In some embodiments, the ablated test surface is positioned along a treatment plane. In some embodiments, light is passed through a wavefront sensor, such as a Hartmann-Shack sensor, to convert the light into electrical signals. A processor then converts the electrical signals into data, such as surface maps showing high-order aberrations and/or artifacts on the test surface, refractive power measurements, shape measurements, and the like. Generated data may then be used to calibrate a laser surgery system.
摘要翻译：波前传感器通过测量消融的测试表面的一个或多个特征来增强激光消融系统的校准，例如激光眼睛手术系统。通常，光通过烧蚀的测试表面，并且分析光以确定测试表面特性。在一些实施例中，烧蚀的测试表面沿着治疗平面定位。在一些实施例中，光通过波前传感器，例如Hartmann-Shack传感器，以将光转换成电信号。然后，处理器将电信号转换成数据，例如在测试表面上显示高阶像差和/或伪影的表面图，折射光焦度测量，形状测量等。然后生成的数据可用于校准激光手术系统。

3. 发明授权

US09358154B2 Presbyopia correction through negative spherical aberration 有权
标题翻译：老花眼矫正通过负球面像差
公开(公告)号：US09358154B2
公开(公告)日：2016-06-07
申请号：US12436743
申请日：2009-05-06
申请人： Seema Somani , Kingman Yee
发明人： Seema Somani , Kingman Yee
IPC分类号： A61F9/01 , A61F9/007 , A61F9/00 , G02C7/04 , A61F9/008
CPC分类号： A61B3/103 , A61B3/1015 , A61F2/164 , A61F9/00 , A61F9/008 , A61F9/00806 , A61F9/00808 , A61F2009/00844 , A61F2009/00872 , A61F2009/0088 , G02C7/041 , G02C7/042 , G02C2202/22
摘要： Devices, systems, and methods for treating and/or determining appropriate prescriptions for one or both eyes of a patient are particularly well-suited for addressing presbyopia, often in combination with concurrent treatments of other vision defects. High-order spherical aberration may be imposed in one or both of a patient's eyes, often as a controlled amount of negative spherical aberration extending across a pupil. A desired presbyopia-mitigating quantity of high-order spherical aberration may be defined by one or more spherical Zernike coefficients, which may be combined with Zernike coefficients generated from a wavefront aberrometer. The resulting prescription can be imposed using refractive surgical techniques such as laser eye surgery, using intraocular lenses and other implanted structures, using contact lenses, using temporary or permanent corneal reshaping techniques, and/or the like.
摘要翻译：用于治疗和/或确定患者的一只眼睛或两只眼睛的适当处方的装置，系统和方法特别适合于解决老花眼，通常与其他视力缺陷的并发治疗相结合。高次球面像差可以施加在患者眼睛的一个或两个中，通常作为延伸穿过瞳孔的受控量的负球面像差。可以通过一个或多个球形Zernike系数来定义所需的老花眼减轻量的高阶球面像差，该Zernike系数可以与从波前像差计产生的Zernike系数组合。所得到的处方可以使用屈光手术技术如激光眼科手术，使用眼内透镜和其它植入结构，使用隐形眼镜，使用临时或永久角膜重塑技术等来实施。

4. 发明授权

US08016420B2 System and method for illumination and fixation with ophthalmic diagnostic instruments 有权
标题翻译：用眼科诊断仪器照明和固定的系统和方法
公开(公告)号：US08016420B2
公开(公告)日：2011-09-13
申请号：US11750291
申请日：2007-05-17
申请人： Kingman Yee , Seema Somani
发明人： Kingman Yee , Seema Somani
IPC分类号： A61B3/10
CPC分类号： A61B3/0091 , A61B3/103
摘要： An eye measurement system may include a target that moves transverse to an optical path from the target to eye, so as to relax accommodation of the lens of the eye. The target may move transverse to the optical path on a display. The patient may be fogged while the target moves transverse to the optical path, and the target may become smaller such that the patient perceives the target to be moving away from the patient. A pupil camera may measure eye position that can be correlated with the position of the target on the display to determine that the patient has maintained fixation on the moving target. A visible measurement light beam may be pulsed subsequent to and/or during motion of the target that relaxes accommodation of the eye so as to avoid visual interference of the measurement light beam with the target on the display.
摘要翻译：眼睛测量系统可以包括横向于从目标到眼睛的光路移动的目标，以便放松眼睛的镜片的适应。目标可以横向于显示器上的光路移动。当目标物横向于光路移动时，患者可能会起雾，并且目标可能变小，使得患者感知到目标物远离患者。瞳孔照相机可以测量可以与显示器上的目标位置相关联的眼睛位置，以确定患者已经维持在移动目标上的固定。可以在目标的运动之前和/或运动期间脉冲可见的测量光束，其放松眼睛的容纳，以避免测量光束与目标在显示器上的视觉干扰。

5. 发明授权

US07652761B2 Methods and systems for laser calibration and eye tracker camera alignment 有权
标题翻译：用于激光校准和眼动仪相机对准的方法和系统
公开(公告)号：US07652761B2
公开(公告)日：2010-01-26
申请号：US12200386
申请日：2008-08-28
申请人： Seema Somani , Kingman Yee , John S. Shimmick
发明人： Seema Somani , Kingman Yee , John S. Shimmick
IPC分类号： G01J1/10
CPC分类号： A61F9/00814 , A61B2017/00725 , A61F9/008 , A61F9/00802 , A61F2009/00846 , A61F2009/00855 , A61F2009/00872 , A61F2009/00897 , B23K26/705 , G01J1/4257 , G01J2001/4261 , G01N21/6456
摘要： The present invention provides methods, systems, and apparatus for calibrating a laser ablation system, such as an excimer laser system for selectively ablating a cornea of a patient's eye. The invention also facilitates alignment of eye tracking cameras that measure a position of the eye during laser eye surgery. A calibration and alignment fixture for a scanning laser beam delivery system having eye tracking cameras may include a structure positionable in a treatment plane. The structure having a feature directing laser energy incident thereon to a calibration energy sensor, at least one reference-edge to determine a characteristic of the laser beam (shape, dimensions, etc.), and an artificial pupil to determine alignment of the eye tracking cameras with the laser system.
摘要翻译：本发明提供了用于校准激光消融系统的方法，系统和装置，例如用于选择性地烧蚀患者眼睛的角膜的准分子激光系统。本发明还有助于在激光眼睛手术期间测量眼睛位置的眼睛跟踪相机的对准。用于具有眼睛跟踪摄像机的扫描激光束传送系统的校准和对准夹具可以包括可在治疗平面中定位的结构。具有将激光能量入射到校准能量传感器的特征的结构，至少一个参考边缘以确定激光束的特性（形状，尺寸等）以及用于确定眼睛跟踪的对准的人造瞳孔相机与激光系统。

6. 发明授权

US07261412B2 Presbyopia correction through negative high-order spherical aberration 有权
公开(公告)号：US07261412B2
公开(公告)日：2007-08-28
申请号：US11173904
申请日：2005-06-30
申请人： Seema Somani , Kingman Yee
发明人： Seema Somani , Kingman Yee
IPC分类号： G02C7/02 , A61B18/18
CPC分类号： A61B3/103 , A61B3/1015 , A61F2/164 , A61F9/00 , A61F9/008 , A61F9/00806 , A61F9/00808 , A61F2009/00844 , A61F2009/00872 , A61F2009/0088 , G02C7/041 , G02C7/042 , G02C2202/22
摘要： Devices, systems, and methods for treating and/or determining appropriate prescriptions for one or both eyes of a patient are particularly well-suited for addressing presbyopia, often in combination with concurrent treatments of other vision defects. High-order spherical aberration may be imposed in one or both of a patient's eyes, often as a controlled amount of negative spherical aberration extending across a pupil. A desired presbyopia-mitigating quantity of high-order spherical aberration may be defined by one or more spherical Zernike coefficients, which may be combined with Zernike coefficients generated from a wavefront aberrometer. The resulting prescription can be imposed using refractive surgical techniques such as laser eye surgery, using intraocular lenses and other implanted structures, using contact lenses, using temporary or permanent corneal reshaping techniques, and/or the like.

7. 发明授权

US08833940B2 System and method for illumination and fixation with ophthalmic diagnostic instruments 有权
标题翻译：用眼科诊断仪器照明和固定的系统和方法
公开(公告)号：US08833940B2
公开(公告)日：2014-09-16
申请号：US13191072
申请日：2011-07-26
申请人： Kingman Yee , Seema Somani
发明人： Kingman Yee , Seema Somani
IPC分类号： A61B3/10 , A61B3/00 , A61B3/103
CPC分类号： A61B3/0091 , A61B3/103
摘要： An eye measurement system may include a target that moves transverse to an optical path from the target to eye, so as to relax accommodation of the lens of the eye. The target may move transverse to the optical path on a display. The patient may be fogged while the target moves transverse to the optical path, and the target may become smaller such that the patient perceives the target to be moving away from the patient. A pupil camera may measure eye position that can be correlated with the position of the target on the display to determine that the patient has maintained fixation on the moving target. A visible measurement light beam may be pulsed subsequent to and/or during motion of the target that relaxes accommodation of the eye so as to avoid visual interference of the measurement light beam with the target on the display.
摘要翻译：眼睛测量系统可以包括横向于从目标到眼睛的光路移动的目标，以便放松眼睛的镜片的适应。目标可以横向于显示器上的光路移动。当目标物横向于光路移动时，患者可能会起雾，并且目标可能变小，使得患者感知到目标物远离患者。瞳孔照相机可以测量可以与显示器上的目标位置相关联的眼睛位置，以确定患者已经维持在移动目标上的固定。可以在目标的运动之前和/或运动期间脉冲可见的测量光束，其放松眼睛的容纳，以避免测量光束与目标在显示器上的视觉干扰。

8. 发明申请

US20110279777A1 System and Method for Illumination and Fixation With Ophthalmic Diagnostic Instruments 有权
标题翻译：用眼科诊断仪器照明和固定的系统和方法
公开(公告)号：US20110279777A1
公开(公告)日：2011-11-17
申请号：US13191072
申请日：2011-07-26
申请人： Kingman Yee , Seema Somani
发明人： Kingman Yee , Seema Somani
IPC分类号： A61B3/10
CPC分类号： A61B3/0091 , A61B3/103
摘要： An eye measurement system may include a target that moves transverse to an optical path from the target to eye, so as to relax accommodation of the lens of the eye. The target may move transverse to the optical path on a display. The patient may be fogged while the target moves transverse to the optical path, and the target may become smaller such that the patient perceives the target to be moving away from the patient. A pupil camera may measure eye position that can be correlated with the position of the target on the display to determine that the patient has maintained fixation on the moving target. A visible measurement light beam may be pulsed subsequent to and/or during motion of the target that relaxes accommodation of the eye so as to avoid visual interference of the measurement light beam with the target on the display.
摘要翻译：眼睛测量系统可以包括横向于从目标到眼睛的光路移动的目标，以便放松眼睛的镜片的适应。目标可以横向于显示器上的光路移动。当目标物横向于光路移动时，患者可能会起雾，并且目标可能变小，使得患者感知到目标物远离患者。瞳孔照相机可以测量可以与显示器上的目标位置相关联的眼睛位置，以确定患者已经维持在移动目标上的固定。可以在目标的运动之前和/或运动期间脉冲可见的测量光束，其放松眼睛的容纳，以避免测量光束与目标在显示器上的视觉干扰。

9. 发明申请

US20090216218A1 PRESBYOPIA CORRECTION THROUGH NEGATIVE SPHERICAL ABERRATION 有权
标题翻译：通过负面球形异常校正的PRESBYOPIA校正
公开(公告)号：US20090216218A1
公开(公告)日：2009-08-27
申请号：US12436743
申请日：2009-05-06
申请人： Seema Somani , Kingman Yee
发明人： Seema Somani , Kingman Yee
IPC分类号： A61F9/008 , A61B18/20
CPC分类号： A61B3/103 , A61B3/1015 , A61F2/164 , A61F9/00 , A61F9/008 , A61F9/00806 , A61F9/00808 , A61F2009/00844 , A61F2009/00872 , A61F2009/0088 , G02C7/041 , G02C7/042 , G02C2202/22
摘要： Devices, systems, and methods for treating and/or determining appropriate prescriptions for one or both eyes of a patient are particularly well-suited for addressing presbyopia, often in combination with concurrent treatments of other vision defects. High-order spherical aberration may be imposed in one or both of a patient's eyes, often as a controlled amount of negative spherical aberration extending across a pupil. A desired presbyopia-mitigating quantity of high-order spherical aberration may be defined by one or more spherical Zernike coefficients, which may be combined with Zernike coefficients generated from a wavefront aberrometer. The resulting prescription can be imposed using refractive surgical techniques such as laser eye surgery, using intraocular lenses and other implanted structures, using contact lenses, using temporary or permanent corneal reshaping techniques, and/or the like.
摘要翻译：用于治疗和/或确定患者的一只眼睛或两只眼睛的适当处方的装置，系统和方法特别适合于解决老花眼，通常与其他视力缺陷的并发治疗相结合。高次球面像差可以施加在患者眼睛的一个或两个中，通常作为延伸穿过瞳孔的受控量的负球面像差。可以通过一个或多个球形Zernike系数来定义所需的老花眼减轻量的高阶球面像差，该Zernike系数可以与从波前像差计产生的Zernike系数组合。所得到的处方可以使用屈光手术技术如激光眼科手术，使用眼内透镜和其它植入结构，使用隐形眼镜，使用临时或永久角膜重塑技术等来实施。

10. 发明申请

US20090000628A1 PRESBYOPIA CORRECTION THROUGH NEGATIVE HIGH-ORDER SPHERICAL ABERRATION 有权
标题翻译：通过负面的高阶球形异常校正进行校正
公开(公告)号：US20090000628A1
公开(公告)日：2009-01-01
申请号：US12207444
申请日：2008-09-09
申请人： Seema Somani , Kingman Yee
发明人： Seema Somani , Kingman Yee
IPC分类号： A61F2/16 , A61B3/10 , A61B19/00
CPC分类号： A61B3/103 , A61B3/1015 , A61F2/164 , A61F9/00 , A61F9/008 , A61F9/00806 , A61F9/00808 , A61F2009/00844 , A61F2009/00872 , A61F2009/0088 , G02C7/041 , G02C7/042 , G02C2202/22
摘要： Devices, systems, and methods for treating and/or determining appropriate prescriptions for one or both eyes of a patient are particularly well-suited for addressing presbyopia, often in combination with concurrent treatments of other vision defects. High-order spherical aberration may be imposed in one or both of a patient's eyes, often as a controlled amount of negative spherical aberration extending across a pupil. A desired presbyopia-mitigating quantity of high-order spherical aberration may be defined by one or more spherical Zernike coefficients, which may be combined with Zernike coefficients generated from a wavefront aberrometer. The resulting prescription can be imposed using refractive surgical techniques such as laser eye surgery, using intraocular lenses and other implanted structures, using contact lenses, using temporary or permanent corneal reshaping techniques, and/or the like.
摘要翻译：用于治疗和/或确定患者的一只眼睛或两只眼睛的适当处方的装置，系统和方法特别适合于解决老花眼，通常与其他视力缺陷的并发治疗相结合。高次球面像差可以施加在患者眼睛的一个或两个中，通常作为延伸穿过瞳孔的受控量的负球面像差。可以通过一个或多个球形Zernike系数来定义所需的老花眼减轻量的高阶球面像差，该Zernike系数可以与从波前像差计产生的Zernike系数组合。所得到的处方可以使用屈光手术技术如激光眼科手术，使用眼内透镜和其它植入结构，使用隐形眼镜，使用临时或永久角膜重塑技术等来实施。

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