专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08933267B2 Compounds for use as anti-ulcer agent and/or anti-Helicobacter pylori agent and pharmaceutical compositions thereof 有权
标题翻译：用作抗溃疡剂和/或抗幽门螺杆菌药物的化合物及其药物组合物
公开(公告)号：US08933267B2
公开(公告)日：2015-01-13
申请号：US14207723
申请日：2014-03-13
申请人： King Saud University
发明人： Amani S. Awaad , Reham Moustafa El-Meligy , Ahmed M. Alafeefy
IPC分类号： C07C311/46 , C07C311/37 , A61K31/195
CPC分类号： C07C311/46
摘要： The present invention relates to a compound according to formula I in particular as anti-ulcer agent and/or anti-Helicobacter pylori agent, wherein R1 is selected from linear or branched C1-C6 alkyl, H, thioether and benzyl, and R2 is selected from linear or branched C1-C10 alkanediyl and pharmaceutical compositions thereof.
摘要翻译：本发明涉及式I化合物，特别是抗溃疡剂和/或抗幽门螺杆菌药物，其中R1选自直链或支链C 1 -C 6烷基，H，硫醚和苄基，R2选自来自直链或支链C 1 -C 10烷二基及其药物组合物。

2. 发明授权

US09233096B2 Method of providing an anti-ulcer treatment with extracts and isolated flavonoids from Euphorbia cuneata 有权
标题翻译：用大戟属提取物和分离的黄酮提供抗溃疡治疗的方法
公开(公告)号：US09233096B2
公开(公告)日：2016-01-12
申请号：US14296711
申请日：2014-06-05
申请人： King Saud University
发明人： Amani S. Awaad , Reham Moustafa El-Meligy
IPC分类号： A61K31/352 , A61K36/47 , A61K31/7048 , A61K31/353 , C07D311/40 , C07H17/07
CPC分类号： A61K31/352 , A61K31/353 , A61K31/7048 , A61K36/47 , A61K2236/30 , C07D311/40 , C07H17/07
摘要： The present invention relates to methods of isolating flavonoids from Euphorbia cuneata, and a pharmaceutical composition comprising the flavonoids or the extracts or both of them for a use as anti-ulcer agent. The present invention further relates to a method of providing an anti-ulcer treatment to an animal in need thereof comprising administering to the animal a compound selected from 4′-methoxy-luteolin-7-O-rhamnoglucoside and aromadendrin. A method of providing an anti-ulcer treatment to an animal in need thereof comprising administering to the animal a compound selected from 4′-methoxy-luteolin-7-O-rhamnoglucoside and aromadendrin, in which the compound(s) are isolated from Euphorbia cuneata.
摘要翻译：本发明涉及从大戟属中分离黄酮类化合物的方法，以及包含类黄酮或其提取物或两者用作抗溃疡剂的药物组合物。本发明还涉及向有需要的动物提供抗溃疡治疗的方法，包括向动物施用选自4'-甲氧基 - 木犀草素-7-O-鼠李糖苷和芳香甙的化合物。向有需要的动物提供抗溃疡治疗的方法包括向动物施用选自4-甲氧基 - 木犀草素-7-O-鼠李糖苷和芳香苷的化合物，其中所述化合物与大戟分离 cuneata

3. 发明授权

US09192639B1 Convolvulus extract for treatment of peptic ulcer and helicobacter pylori infection 有权
标题翻译：旋花提取物用于治疗消化性溃疡和幽门螺杆菌感染
公开(公告)号：US09192639B1
公开(公告)日：2015-11-24
申请号：US14497265
申请日：2014-09-25
申请人： KING SAUD UNIVERSITY
发明人： Amani S. Awaad , Asma'a Al-Rifai , Reham M. El-Meligy , Mohamed E. Zain
IPC分类号： A61K36/00 , A61K36/39 , A61K31/235
CPC分类号： A61K31/235 , A61K36/39 , A61K2236/00
摘要： The Convolvulus extract for treating peptic ulcer and Helicobacter pylori infection is an ethanolic extract from C. pilosellifolius. The extract is prepared by homogenizing Convolvulus pilosellifolius aerial plant parts to prepare a powder, percolating the powder with an organic solvent to prepare a suspension, filtering the suspension to obtain a filtrate, and obtaining the extract as a dry powder by drying the solvent under reduced pressure from the filtrate. The active ingredient in the extract is a compound that was isolated from the extract of C. pilosellifolius as a purified triterpene using silica gel column chromatography, the compound being named: 2-propoxyethyl 13-(4-ethoxy-4-oxobutyl)-6b,8a12b,14a-tetramethyl-5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,14a-tetradecahydropicene-2-carboxylate. Both the extract and the isolated active ingredient exhibit anti-ulcerogenic activity, and disk diffusion tests show that various strains of H. pylori are susceptible to both the extract and the active ingredient.
摘要翻译：用于治疗消化性溃疡和幽门螺旋杆菌感染的旋花提取物是来自C. pilosellifolius的乙醇提取物。该提取物是通过将旋风螺旋体空间植物部分匀化以制备粉末，用有机溶剂渗透粉末以制备悬浮液，过滤悬浮液以获得滤液，并通过在减压下干燥溶剂获得干粉末的提取物滤液压力。提取物中的活性成分是使用硅胶柱色谱从作为纯化三萜的C.ploslosifolius的提取物中分离的化合物，该化合物命名为：2-丙氧基乙基13-（4-乙氧基-4-氧代丁基）-6b ，8a12b，14a-四甲基-5,6,6a，6b，7,8,8a，9,10,11,12,12a，12b，14a-十四碳氢化合物-2-羧酸酯。提取物和分离的活性成分均表现出抗溃疡活性，圆盘扩散试验显示幽门螺杆菌的各种菌株对提取物和活性成分都敏感。

4. 发明授权

US09073500B2 Thermal insulation construction and a method for the preparation thereof 有权
标题翻译：隔热结构及其制备方法
公开(公告)号：US09073500B2
公开(公告)日：2015-07-07
申请号：US14021016
申请日：2013-09-09
申请人： King Saud University
发明人： Amani S. Awaad , Reham Moustafa El-Meligy , Sara H. Alqahtani , Hessa E. Alduhailan
IPC分类号： B60R13/08 , E04B1/76 , E04C2/16 , E04B1/74
CPC分类号： B60R13/0815 , E04B1/76 , E04B1/7675 , E04B2001/745 , E04C2/16 , Y02A30/245
摘要： The present invention relates to a thermal insulation construction comprising a support and a thermal insulation layer thereon, wherein the thermal insulation layer comprises an extract from a plant material obtainable from Aloe Vera, a method for the preparation thereof and its use, in particular, for thermal insulating a vehicle interior.
摘要翻译：本发明涉及一种在其上包括支撑体和绝热层的绝热结构，其中绝热层包括可从芦荟获得的植物材料的提取物，其制备方法及其用途，特别是用于隔热车辆内部。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式