专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20080112910A1 Cool feeling composition, cool feeling auxiliary composition, and use thereof 审中-公开
标题翻译：酷感组合，凉爽感觉辅助组合物及其用途
公开(公告)号：US20080112910A1
公开(公告)日：2008-05-15
申请号：US12003609
申请日：2007-12-28
申请人： Kenya Ishida , Kazutoshi Sakurai
发明人： Kenya Ishida , Kazutoshi Sakurai
IPC分类号： A61K8/37 , A61K8/31
CPC分类号： A61Q19/00 , A23L27/204 , A61K8/34 , A61K8/345 , A61K8/37 , A61K8/42 , A61K9/0014 , A61K47/10 , A61K47/14 , A61Q5/02 , A61Q11/00 , A61Q11/02 , A61Q13/00 , C09K5/00
摘要： The cool feeling composition of the present invention obtained by combining a cool feeling substance containing at least one compound selected from 1-menthol, isopulegol, 3-(1-menthoxy)propane-1,2-diol, 2-(1-menthoxy)ethan-1-ol, 3-(1-menthoxy)propan-1-ol, 2-methyl-3-(1-menthoxy)propane-1,2-diol, N-ethyl-1-menthylcarboxamide, p-menthane-3,8-diol, 1-menthyl lactate, and 2-isopropyl-N,2,3-trimethylbutanamide with a salicylic acid ester represented by the following general formula (I), such as 2-hydroxyethyl salicylate, improves strength and persistency of cool feeling effect, particularly, those containing 1-menthol as the cool feeling substance can alleviate the irritant fragrance note resulting from 1-menthol. Mixing of the cool feeling composition or fragrance composition containing the same with products such as foods and drinks, cosmetics, toiletry products, bath agents, and pharmaceuticals can afford products wherein the above features of the cool feeling composition of the invention are effectively exerted. wherein R represents a hydrocarbon group having 1 to 18 carbon atoms which may has a substituent.
摘要翻译：通过将含有至少一种选自1-薄荷醇，异铃兰，3-（1-薄荷氧基）丙烷-1,2-二醇，2-（1-薄荷氧基）丙烷-1,2-二醇的化合物的冷却物质组合得到的本发明的凉爽感觉组合物，乙-1-醇，3-（1-薄荷氧基）丙-1-醇，2-甲基-3-（1-薄荷氧基）丙烷-1,2-二醇，N-乙基-1-薄荷基甲酰胺，对薄荷烷 - 3,5-二醇，1-薄荷酸乳酸酯和2-异丙基-N，2,3-三甲基丁酰胺与下列通式（I）表示的水杨酸酯如水杨酸2-羟乙酯提高了强度和持久性特别是含有1-薄荷醇作为凉爽感觉物质的感觉效果可以减轻由1-薄荷醇引起的刺激性香味。混合含有食品和饮料，化妆品，化妆品，浴剂和药物的产品的凉爽感觉组合物或香料组合物可以得到有效发挥本发明的凉爽感觉组合物的上述特征的产品。其中R表示可具有取代基的碳原子数1〜18的烃基。

2. 发明授权

US5998668A Optically active compound and process for producing the same 失效
标题翻译：光学活性化合物及其制备方法
公开(公告)号：US5998668A
公开(公告)日：1999-12-07
申请号：US17239
申请日：1998-02-02
申请人： Kazutoshi Sakurai , Kenya Ishida , Miharu Ogura
发明人： Kazutoshi Sakurai , Kenya Ishida , Miharu Ogura
IPC分类号： C07C231/16 , C07C231/18 , C07C235/08 , C07C233/05 , C07C231/02
CPC分类号： C07C231/18 , C07C235/08 , C07B2200/07
摘要： An optically active (2S,3R)-2-(3'-hydroxyacyl)aminoalkane-1,3-diol and a process for producing the same are disclosed. The compound is represented by the following general formula (1): ##STR1## wherein R.sup.1 represents a linear or branched, saturated aliphatic hydrocarbon group having 9 to 19 carbon atoms; R.sup.2 represents a linear or branched, saturated aliphatic hydrocarbon group having 1 to 19 carbon atoms; and symbol * means that the carbon atom is an asymmetric carbon atom of the S or R configuration. The optically active compound is a ceramide in which the fatty acid moiety has an optically active hydroxyl group in the 3-position.
摘要翻译：公开了光学活性（2S，3R）-2-（3'-羟基酰基）氨基烷-1,3-二醇及其制备方法。该化合物由以下通式（1）表示：其中R1表示具有9至19个碳原子的直链或支链饱和脂族烃基; R2表示碳原子数为1〜19的直链或支链饱和脂肪族烃基; 符号*表示碳原子是S或R构型的不对称碳原子。光学活性化合物是其中脂肪酸部分在3-位具有光学活性羟基的神经酰胺。

3. 发明授权

US5831125A Method of making primary amide derivative 失效
标题翻译：制备伯酰胺衍生物的方法
公开(公告)号：US5831125A
公开(公告)日：1998-11-03
申请号：US843838
申请日：1997-04-17
申请人： Kazutoshi Sakurai , Kenya Ishida , Miharu Ogura
发明人： Kazutoshi Sakurai , Kenya Ishida , Miharu Ogura
IPC分类号： C07C231/16 , C07C231/02 , C07C233/18 , C07C233/20 , C07C235/08 , C07C231/08 , C07C231/10
CPC分类号： C07C231/02
摘要： A method of selective N-acylation of an aminodiol having a primary alcoholic hydroxyl group and a secondary alcoholic hydroxyl group, in which the objective product can be prepared in high yield and without troublesome extraction and purification operations. More particularly, a method of making a primary amide derivative represented by the following general formula (3) is disclosed: ##STR1## wherein R.sup.1 represents a linear saturated aliphatic hydrocarbon group having 11 to 19 carbon atoms, R.sup.2 represents a linear saturated or unsaturated aliphatic hydrocarbon group having 9 to 19 carbon atoms which may have a hydroxyl group at the 1-position, which includes the steps of reacting an aminodiol represented by the following general formula (1): ##STR2## wherein R.sup.1 is the same as R.sup.1 in general formula (3) with a fatty acid alkyl ester represented by the following general formula (2): R.sup.2 --COO--R.sup.3 (2) wherein R.sup.2 is the same as R.sup.2 in general formula (3) and R.sup.3 represents a lower alkyl group, in a reaction system comprising an alcoholic solvent and in the presence of a basic catalyst, said reacting step forming a lower alcohol as a by-product; and removing the lower alcohol formed during the reaction from the reaction system.
摘要翻译：具有初级醇羟基和仲醇羟基的氨基二醇的选择性N-酰化的方法，其中可以高产率制备目标产物并且不需要麻烦的提取和纯化操作。更具体地说，公开了制备由以下通式（3）表示的伯酰胺衍生物的方法：其中R1表示具有11至19个碳原子的直链饱和脂族烃基，R2表示直链饱和或可以在1位具有羟基的碳原子数9〜19的不饱和脂肪族烃基，其包括使下述通式（1）表示的氨基二醇反应的步骤：其中R1为与通式（3）中的R 1与由以下通式（2）表示的脂肪酸烷基酯相同：R2-COO-R3（2）其中R2与通式（3）中的R2相同，R3表示在含有醇溶剂的反应体系中，在碱性催化剂的存在下，所述反应步骤形成作为副产物的低级醇; 并从反应体系中除去反应期间形成的低级醇。

4. 发明授权

US5786386A Antibacterial and fungicidal agent 失效
标题翻译：抗菌杀菌剂
公开(公告)号：US5786386A
公开(公告)日：1998-07-28
申请号：US678598
申请日：1996-07-15
申请人： Kenya Ishida , Kazutoshi Sakurai
发明人： Kenya Ishida , Kazutoshi Sakurai
IPC分类号： A01N33/04 , A01N33/06 , A01N33/10 , A01N43/30 , A01N43/50 , C07C217/58 , C07D233/54 , C07D317/58
CPC分类号： C07D233/64 , A01N33/04 , A01N33/06 , A01N33/10 , A01N43/30 , A01N43/50 , C07C217/58 , C07D317/58
摘要： The present invention provides an antibacterial and fungicidal agent containing an amino compound of formula (1) or a salt thereof. The invention also provides a method for imparting antibacterial and fungicidal properties to a variety of objects using the compound. ##STR1## wherein .phi. represents a phenyl group, a substituted phenyl group (wherein the substituents are 1-5 members arbitrarily selected from the group consisting of a hydroxyl group, halogen atoms, lower alkoxyl groups, trifluoromethyl group, an amino group, and a methylenedioxy group), or an imidazolyl group; R.sup.1 represents a hydrogen atom or a lower alkyl group; and R.sup.2 represents a C6-C12 alkyl group. The amino compound of formula (1) or a salt thereof exhibits excellent antibacterial effects and fungicidal effects, and when it is applied to a variety of articles used in industry, commodities, etc., enhanced antibacterial effects and fungicidal effects are obtained.
摘要翻译：本发明提供含有式（1）的氨基化合物或其盐的抗细菌剂和杀真菌剂。本发明还提供了使用该化合物赋予各种物体抗菌和杀真菌性能的方法。（1）其中phi表示苯基，取代的苯基（其中取代基任选地选自羟基，卤素原子，低级烷氧基，三氟甲基，氨基，和亚甲二氧基）或咪唑基; R1表示氢原子或低级烷基; R2代表C6-C12烷基。式（1）的氨基化合物或其盐具有优异的抗菌效果和杀真菌效果，并且当其应用于工业，商品等中使用的各种制品时，获得了增强的抗菌效果和杀真菌效果。

5. 发明授权

US06379659B1 Keratin fiber strengthening agent and method for strengthening keratin fiber 失效
标题翻译：角蛋白纤维增强剂及加强角蛋白纤维的方法
公开(公告)号：US06379659B1
公开(公告)日：2002-04-30
申请号：US09193731
申请日：1998-11-17
申请人： Kenya Ishida , Kazutoshi Sakurai , Miharu Ogura , Tetsuro Yamasaki , Kenichiro Shiroyama
发明人： Kenya Ishida , Kazutoshi Sakurai , Miharu Ogura , Tetsuro Yamasaki , Kenichiro Shiroyama
IPC分类号： A61K706
CPC分类号： A61K8/68 , A61Q5/04
摘要： A keratin fiber strengthening agent comprising 0.001 to 20% by weight of at least one (2S,3R)-2-acylaminoalkane-1,3-diol represented by formula (I): wherein R1 represents a straight-chain alkyl group having 9 to 17 carbon atoms; and R2 represents an acyl group having 2 to 24 carbon atoms which may contain at least one hydroxy group or unsaturated bond is disclosed. A method for improving physical properties, such as breaking strength, of keratin fiber such as hair comprising applying the keratin fiber strengthening agent to keratin fiber by adhesion, coating or impregnation is also disclosed.
摘要翻译：一种角蛋白纤维增强剂，其包含0.001至20重量％的由式（I）表示的至少一种（2S，3R）-2-酰基氨基烷-1,3-二醇：其中R1表示直链烷基，其具有9至 17个碳原子; 并且R 2表示可以含有至少一个羟基或不饱和键的碳原子数为2〜24的酰基。还公开了用于改善角蛋白纤维如头发的物理性能如断裂强度的方法，其包括通过粘附，涂覆或浸渍将角蛋白纤维增强剂施用于角蛋白纤维。

6. 发明授权

US5925792A Process for preparing 2-amino-1,3-alkanediol or derivative thereof, process for preparing optically active dihydrosphingosine derivative, and intermediates for optically active dihydrosphingosine derivative 失效
标题翻译：制备2-氨基-1,3-链烷二醇或其衍生物的方法，制备光学活性二氢鞘氨醇衍生物的方法和光学活性二氢鞘氨醇衍生物的中间体
公开(公告)号：US5925792A
公开(公告)日：1999-07-20
申请号：US696161
申请日：1996-08-13
申请人： Kazutoshi Sakurai , Kenya Ishida
发明人： Kazutoshi Sakurai , Kenya Ishida
IPC分类号： C07B53/00 , C07B61/00 , C07C213/00 , C07C213/08 , C07C215/10 , C07C229/22 , C07D303/48 , C07C209/00
CPC分类号： C07D303/48 , C07C213/08 , C07C229/22 , Y02P20/55
摘要： A process for preparing an optically active dihydrosphingosine derivative is disclosed, comprising reducing a (2R,3R)-2-amino-3-hydroxyalkanoic acid derivative represented by formula (III): ##STR1## wherein R.sup.3 represents a straight-chain alkyl group having 7 to 21 carbon atoms; and R.sup.4 represents an amino group protecting group, (e.g., (2R,3R)-2-benzylamino-3-hydroxyoctadecanoic acid) with sodium tetrahydroborate in the presence of an acid. The process makes it feasible to produce an optically active dihydrosphingosine at high optical purity and through a simple process that is safe and easy to industrialize.
摘要翻译：公开了一种制备光学活性二氢鞘氨醇衍生物的方法，包括还原由式（III）表示的（2R，3R）-2-氨基-3-羟基链烷酸衍生物：其中R 3表示具有7-21个碳原子的直链烷基碳原子和R4代表氨基保护基团（例如（2R，3R）-2-苄基氨基-3-羟基十八烷酸）与四氢硼酸钠在酸存在下反应。该方法使得生产具有高光学纯度的光学活性二氢鞘氨醇和通过安全且容易工业化的简单方法是可行的。

7. 发明申请

US20050129721A1 Refrigerant composition, refrigerant auxiliary compositions and uses thereof 审中-公开
标题翻译：制冷剂组合物，制冷剂辅助组合物及其用途
公开(公告)号：US20050129721A1
公开(公告)日：2005-06-16
申请号：US10506187
申请日：2003-02-28
申请人： Kenya Ishida , Kazutoshi Sakurai
发明人： Kenya Ishida , Kazutoshi Sakurai
IPC分类号： A23L27/20 , A23L29/00 , A61K8/34 , A61K8/37 , A61K8/42 , A61K9/00 , A61K47/10 , A61K47/14 , A61Q5/00 , A61Q11/00 , A61Q11/02 , A61Q13/00 , A61Q90/00 , C09K5/00 , A61K7/00 , A61K31/045 , A61K31/16 , A61K31/22 , A61K31/60
CPC分类号： A61Q19/00 , A23L27/204 , A61K8/34 , A61K8/345 , A61K8/37 , A61K8/42 , A61K9/0014 , A61K47/10 , A61K47/14 , A61Q5/02 , A61Q11/00 , A61Q11/02 , A61Q13/00 , C09K5/00
摘要： The cool feeling composition of the present invention obtained by combining a cool feeling substance containing at least one compound selected from 1-menthol, isopulegol, 3-(1-menthoxy)propane-1,2-diol, 2-(1-menthoxy)ethan-1-ol, 3-(1-menthoxy)propan-1-ol, 2-methyl-3-(1-menthoxy)propane-1,2-diol, N-ethyl-l-menthylcarboxamide, p-menthane-3,8-diol, 1-menthyl lactate, and 2-isopropyl-N, 2,3-trimethylbutanamide with a salicylic acid ester represented by the following general formula (I), such as 2-hydroxyethyl salicylate, improves strength and persistency of cool feeling effect, particularly, those containing 1-menthol as the cool feeling substance can alleviate the irritant fragrance note resulting from 1-menthol. Mixing of the cool feeling composition or fragrance composition containing the same with products such as foods and drinks, cosmetics, toiletry products, bath agents, and pharmaceuticals can afford products wherein the above features of the cool feeling composition of the invention are effectively exerted. wherein R represents a hydrocarbon group having 1 to 18 carbon atoms which may has a substituent.
摘要翻译：通过将含有至少一种选自1-薄荷醇，异铃兰，3-（1-薄荷氧基）丙烷-1,2-二醇，2-（1-薄荷氧基）丙烷-1,2-二醇的化合物的冷却物质组合得到的本发明的凉爽感觉组合物，乙-1-醇，3-（1-薄荷氧基）丙-1-醇，2-甲基-3-（1-薄荷氧基）丙烷-1,2-二醇，N-乙基-1-薄荷基甲酰胺，对薄荷烷 - 3,5-二醇，1-薄荷酸乳酸酯和2-异丙基-N，2,3-三甲基丁酰胺与下列通式（I）表示的水杨酸酯如水杨酸2-羟乙酯提高了强度和持久性特别是含有1-薄荷醇作为凉爽感觉物质的感觉效果可以减轻由1-薄荷醇引起的刺激性香味。混合含有食品和饮料，化妆品，化妆品，浴剂和药物的产品的凉爽感觉组合物或香料组合物可以得到有效发挥本发明的凉爽感觉组合物的上述特征的产品。其中R表示可具有取代基的碳原子数1〜18的烃基。

8. 发明授权

US06355627B1 Branched cyclodextrin clathrate compound of hinokitiols and composition containing the same 失效
标题翻译：支链环糊精包合物的包合物和含有它的组合物
公开(公告)号：US06355627B1
公开(公告)日：2002-03-12
申请号：US09244106
申请日：1999-02-04
申请人： Kenya Ishida , Kazutoshi Sakurai
发明人： Kenya Ishida , Kazutoshi Sakurai
IPC分类号： A61K31715
CPC分类号： C08B37/0015 , A61K8/35 , A61K8/738 , A61K2800/56 , A61Q5/00 , A61Q5/02 , A61Q11/00 , A61Q17/005 , A61Q19/00 , A61Q19/10
摘要： The invention has an object of providing a hinokitiol which is not damaged in the antibacterial activity and improved in the water solubility, heat stability (anti-sublimation characteristics) and corrosion to metals and also providing a composition comprising a hinokitiol. The invention resides in a clathrate compound comprising clathration of hinokitiols by using a branched cyclodextrin such as a branched &bgr;-cyclodextrin. The clathrate compound can be used in various applications requiring an antibacterial activity, such as hair cosmetics, bath agents, skin cosmetics and oral compositions.
摘要翻译：本发明的目的是提供一种在抗菌活性中不受损害并提高水溶性，热稳定性（抗升华特性）和对金属的腐蚀并且还提供包含扁柏酚的组合物的桧醇。本发明涉及一种包合化合物，其包括通过使用支链环糊精如支链β-环糊精来包合桧醇醇。包合化合物可以用于需要抗菌活性的各种应用中，例如头发化妆品，浴剂，皮肤化妆品和口服组合物。

9. 发明授权

US07030070B2 Composition for hard article surface cleaning liquid 失效
标题翻译：硬物品表面清洗液的组成
公开(公告)号：US07030070B2
公开(公告)日：2006-04-18
申请号：US10634915
申请日：2003-08-06
申请人： Kazutoshi Sakurai , Hideaki Ohta
发明人： Kazutoshi Sakurai , Hideaki Ohta
IPC分类号： C11D3/50
CPC分类号： C11D3/2075 , C11D3/50
摘要： A fragrant compound or fragrant composition stable for a long period of time in an acidic hard article surface cleaning liquid adjusted so as to be acidic, particularly to pH 2.0 to 3.0 with an organic acid. One or more of fragrant compounds selected from the group consisting of 2,6-dimethyl-2-heptanol, 3,3-dimethylcyclohexyl methyl ketone, o-tert-butylcyclohexanol, α-amylcinnamic aldehyde, α-damascone, γ-octalactone, γ-nonalactone, γ-decalactone, anethole, ethyl benzoate, ethyl 2,2,6-trimethylcyclohexanecarboxylate, 2,2,6-trimethyl-1-crotonylcyclohexane, 6-acetyl-1,1,2,4,4,7-hexamethyltetrahydronaphthalene, isoamyl phenylethyl ether, methyl octin carbonate, 6,7-dihydro-1,1,2,3,3-pentamethyl-4(5H)-indanone, tricyclodecenyl acetate, undecyl aldehyde, fenchyl acetate, dihydrojasmone, cedryl methyl ether, p-cresol, hexyl aldehyde, and rosephenone are stable.
摘要翻译：在酸性硬的制品表面清洗液中长时间稳定的芳香化合物或芳香组合物被调节至酸性，特别是用有机酸调至pH2.0至3.0。一种或多种选自2,6-二甲基-2-庚醇，3,3-二甲基环己基甲基酮，邻叔丁基环己醇，α-戊基肉桂醛，α-大黄酮，γ-八聚内酯，γ- 壬内酯，γ-癸内酯，茴香脑，苯甲酸乙酯，2,2,6-三甲基环己烷羧酸乙酯，2,2,6-三甲基-1-丁烯基环己烷，6-乙酰基-1,1,2,4,4,7-六甲基四氢化萘，异戊基苯基乙基醚，甲基辛烯碳酸酯，6,7-二氢-1,1,2,3,3-五甲基-4（5H） - 茚满酮，乙酸三环癸酯，十一烷基醛，乙酸戊酯，二氢茉莉酮，柏木甲基醚， - 甲酚，己醛和rosephenone是稳定的。

10. 发明授权

US06811789B2 Fragrant composition having mosquito-repelling effect 失效
标题翻译：具有驱蚊效果的芬芳成分
公开(公告)号：US06811789B2
公开(公告)日：2004-11-02
申请号：US10282156
申请日：2002-10-29
申请人： Kazutoshi Sakurai , Masataka Miyasaka , Yasutaka Mishima
发明人： Kazutoshi Sakurai , Masataka Miyasaka , Yasutaka Mishima
IPC分类号： A01N2502
CPC分类号： A01N31/02 , A01N35/06 , Y10S424/10 , Y10S514/919 , A01N2300/00
摘要： A mosquito-repelling agent which is gentle to human and environment and safe, and has an excellent mosquito-repelling effect almost equal to the effect of DEET and also an excellent persistency of the effect. The mosquito-repelling agent comprises a mixture of isomenthone, linalool, geraniol, citral and citronellol as an effective ingredient for a mosquito-repelling effect, which may be contained in a fragrant composition.
摘要翻译：一种对人体和环境温和，安全的防蚊剂，具有与DEET效果几乎相当的极好的驱蚊效果，并且效果优异。灭蚊剂包括异麦芽酮醇，芳樟醇，香叶醇，柠檬醛和香茅醇的混合物，作为可以包含在香料组合物中的驱蚊效果的有效成分。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式