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    • 3. 发明授权
    • Cold spray mass spectrometric device
    • 冷喷雾质谱仪
    • US06977369B2
    • 2005-12-20
    • US10343329
    • 2002-06-05
    • Kentaro YamaguchiTatsuji Kobayashi
    • Kentaro YamaguchiTatsuji Kobayashi
    • H01J49/04H01J49/00
    • H01J49/0468B05B5/001B05B5/0255H01J49/044H01J49/165
    • The instrument cold sprays a solution sample at a low temperature and desolvates the sample. Under this condition, a mass analysis is performed. The instrument comprises a needle pipe (8) through which the solution sample is passed, a sheath tube (24) formed coaxially with the needle pipe (8) and passing a temperature-controlled nebulizing gas therethrough, the above-described desolvation block (3), means for cooling the block (15), means for heating the block (4), and a temperature sensor (5) for detecting the temperature of the block (3). The block (3) has a passage for charged liquid droplets of the solution sample cold sprayed from the tip of the needle pipe (8), and acts to remove the solvent from the charged liquid droplets flowing through the passage. A coldspray mass spectrometer is offered which has a desolvation block whose temperature can be easily controlled. In the instrument, condensation of water and electrical leakage are prevented for a long time. The instrument can perform measurements stably and is easy to handle.
    • 仪器冷却在低温下喷射溶液样品并使样品脱水。 在这种条件下,进行质量分析。 该仪器包括通过溶液样品的针管(8),与针管(8)同轴形成并通过温度控制的雾化气体的鞘管(24),上述去溶剂化块(3) ),用于冷却块(15)的装置,用于加热块(4)的装置和用于检测块(3)的温度的温度传感器(5)。 块(3)具有从针管(8)的尖端冷喷射的溶液样品的带电液滴的通道,并且用于从流经通道的带电液滴中除去溶剂。 提供了一种冷喷射质谱仪,其具有一个去溶剂化块,其温度可以容易地控制。 在仪器中,长时间防止水和漏电的结露。 仪器可以稳定地进行测量并且易于处理。
    • 5. 发明授权
    • Method and apparatus for electrospray mass spectrometric analysis
    • 电喷雾质谱分析方法和装置
    • US06642515B1
    • 2003-11-04
    • US09936938
    • 2001-09-20
    • Kentaro Yamaguchi
    • Kentaro Yamaguchi
    • H01J4910
    • H01J49/165G01N27/62
    • The invention is provides a method and an apparatus for performing electrospray ionization mass spectrometric analysis, which method can exactly analyze a mass of a molecular ion or a fragment ion of an unstable organometallic complex or a polymeric organic compound. The method includes cooling a sample to be analyzed which contains a solvent and is caused to flow out from a spray small-diameter tube with an inert gas for low temperature vaporization (A), and carrying out ionization and mass spectrometric analysis of the sample to be analyzed while cooling a chamber (7) for removing a solvent or an ion source shield (8) with liquid nitrogen.
    • 本发明提供了一种用于进行电喷雾离子化质谱分析的方法和装置,该方法可以精确地分析不稳定的有机金属络合物或聚合有机化合物的分子离子或片段离子的质量。 该方法包括冷却含有溶剂的待分析样品,并用用于低温蒸发的惰性气体(A)从喷雾小径管流出,并进行样品的电离和质谱分析 在冷却用于用液氮除去溶剂或离子源屏蔽(8)的室(7)的同时进行分析。