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1. 发明授权

US07200094B2 Reproduced signal evaluation apparatus and method, reproduction apparatus and method, and recording apparatus and method 有权
标题翻译：再生信号评价装置及方法，再现装置和方法以及记录装置和方法
公开(公告)号：US07200094B2
公开(公告)日：2007-04-03
申请号：US11113557
申请日：2005-04-25
申请人： Kensuke Fujimoto , Shunji Yoshimura , Atsushi Fukumoto , Yasuhito Tanaka
发明人： Kensuke Fujimoto , Shunji Yoshimura , Atsushi Fukumoto , Yasuhito Tanaka
IPC分类号： G11B5/76
CPC分类号： G11B20/10009 , G11B7/005 , G11B7/1267 , G11B11/10515 , G11B11/1053 , G11B11/10595 , G11B20/10 , G11B20/18 , G11B20/1833 , H03M13/3961 , H03M13/41 , H03M13/6343
摘要： The present invention provides an apparatus and a method for precisely and adequately evaluating actual quality of reproduced data whenever applying a maximum likelihood decoder for converting signal reproduced from a recording medium into binary signal Based on data arrays of a pair of binary data outputted from a “Viterbi” decoder, SAM values are secured by selecting any of path-metric differential values (00) and (11) being the difference between a pair of values compared when renewing path-metric values PMM (00) and (11) outputted from the “Viterbi” decoder. The minimum SAM value for an ideally-reproduced signal is outputted from a constant generating circuit. If the SAM values are verified as valid, and yet, if the SAM values coincide with the equation “input SAM values”≦“data value outputted from the constant generating circuit”, then squared values outputted from a square circuit are averaged by an averaging circuit. Finally, the average value is outputted as the reproduced signal evaluation.
摘要翻译：本发明提供了一种用于在将用于将从记录介质再现的信号转换为二进制信号的最大似然解码器的情况下精确地和适当地评估再现数据的实际质量的装置和方法。基于从“ 维特比“解码器，通过选择路径度量差分值（00）和（11）中的任何一个来确保SAM值，所述差分值是当从更新路由度量值PMM（00）和（11）更新时比较的一对值之间的差 “维特比”解码器。理想再现信号的最小SAM值从恒定发生电路输出。如果SAM值被验证为有效，然而，如果SAM值与从常数产生电路输出的等式“输入SAM值”<=“数据值”一致，则从平方电路输出的平方值由平均电路。最后，平均值作为再现信号评估输出。

2. 发明授权

US06940800B2 Reproduced signal evaluation apparatus and method, reproduction apparatus and method, and recording apparatus and method 失效
标题翻译：再生信号评价装置及方法，再现装置和方法以及记录装置和方法
公开(公告)号：US06940800B2
公开(公告)日：2005-09-06
申请号：US10017156
申请日：2001-12-14
申请人： Kensuke Fujimoto , Shunji Yoshimura , Atsushi Fukumoto , Yasuhito Tanaka
发明人： Kensuke Fujimoto , Shunji Yoshimura , Atsushi Fukumoto , Yasuhito Tanaka
IPC分类号： G11B7/0045 , G11B7/005 , G11B20/10 , G11B20/18 , H03M13/39 , H03M13/41 , G11B5/76
CPC分类号： G11B20/10009 , G11B7/005 , G11B7/1267 , G11B11/10515 , G11B11/1053 , G11B11/10595 , G11B20/10 , G11B20/18 , G11B20/1833 , H03M13/3961 , H03M13/41 , H03M13/6343
摘要： The present invention provides an apparatus and a method for precisely and adequately evaluating actual quality of reproduced data whenever applying a maximum likelihood decoder for converting signal reproduced from a recording medium into binary signal. Based on data arrays of a pair of binary data outputted from a “Viterbi” decoder, SAM values are secured by selecting any of path-metric differential values (00) and (11) being the difference between a pair of values compared when renewing path-metric values PMM (00) and (11) outputted from the “Viterbi” decoder. The minimum SAM value for an ideally-reproduced signal is outputted from a constant generating circuit. If the SAM values are verified as valid, and yet, if the SAM values coincide with the equation “input SAM values”≦“data value outputted from the constant generating circuit”, then squared values outputted from a square circuit are averaged by an averaging circuit. Finally, the average value is outputted as the reproduced signal evaluation.
摘要翻译：本发明提供了一种用于在应用用于将从记录介质再现的信号转换成二进制信号的最大似然解码器时，精确且充分地评估再现数据的实际质量的装置和方法。基于从“维特比”解码器输出的一对二进制数据的数据阵列，通过选择路径度量差分值（00）和（11）中的任一个作为在更新路径上比较的一对值之间的差异来确保SAM值从“维特比”解码器输出的测量值PMM（00）和（11）。理想再现信号的最小SAM值从恒定发生电路输出。如果SAM值被验证为有效，然而，如果SAM值与从常数产生电路输出的等式“输入SAM值”<=“数据值”一致，则从平方电路输出的平方值由平均电路。最后，平均值作为再现信号评估输出。

3. 发明申请

US20050190630A1 Reproduced signal evaluation apparatus and method, reproduction apparatus and method, and recording apparatus and method 有权
标题翻译：再生信号评价装置及方法，再现装置和方法以及记录装置和方法
公开(公告)号：US20050190630A1
公开(公告)日：2005-09-01
申请号：US11113557
申请日：2005-04-25
申请人： Kensuke Fujimoto , Shunji Yoshimura , Atsushi Fukumoto , Yasuhito Tanaka
发明人： Kensuke Fujimoto , Shunji Yoshimura , Atsushi Fukumoto , Yasuhito Tanaka
IPC分类号： G11B7/0045 , G11B7/005 , G11B20/10 , G11B20/18 , H03M13/39 , H03M13/41 , G11C8/00
CPC分类号： G11B20/10009 , G11B7/005 , G11B7/1267 , G11B11/10515 , G11B11/1053 , G11B11/10595 , G11B20/10 , G11B20/18 , G11B20/1833 , H03M13/3961 , H03M13/41 , H03M13/6343
摘要： The present invention provides an apparatus and a method for precisely and adequately evaluating actual quality of reproduced data whenever applying a maximum likelihood decoder for converting signal reproduced from a recording medium into binary signal Based on data arrays of a pair of binary data outputted from a “Viterbi” decoder, SAM values are secured by selecting any of path-metric differential values (00) and (11) being the difference between a pair of values compared when renewing path-metric values PMM (00) and (11) outputted from the “Viterbi” decoder. The minimum SAM value for an ideally-reproduced signal is outputted from a constant generating circuit. If the SAM values are verified as valid, and yet, if the SAM values coincide with the equation “input SAM values”≦“data value outputted from the constant generating circuit”, then squared values outputted from a square circuit are averaged by an averaging circuit. Finally, the average value is outputted as the reproduced signal evaluation.
摘要翻译：本发明提供了一种用于在将用于将从记录介质再现的信号转换为二进制信号的最大似然解码器的情况下精确地和适当地评估再现数据的实际质量的装置和方法。基于从“ 维特比“解码器，通过选择路径度量差分值（00）和（11）中的任何一个来确保SAM值，所述差分值是当从更新路由度量值PMM（00）和（11）更新时比较的一对值之间的差 “维特比”解码器。理想再现信号的最小SAM值从恒定发生电路输出。如果SAM值被验证为有效，然而，如果SAM值与从常数产生电路输出的等式“输入SAM值”<=“数据值”一致，则从平方电路输出的平方值由平均电路。最后，平均值作为再现信号评估输出。

4. 发明申请

US20140302082A1 NUCLEIC ACID CONSTRUCT COMPRISING NUCLEIC ACID DERIVED FROM GENOME OF HEPATITIS C VIRUS OF GENOTYPE 1B, HEPATITIS C VIRUS GENOME-REPLICATING CELLS TRANSFECTED WITH THE SAME, AND METHOD FOR PRODUCING INFECTIOUS HEPATITIS C VIRUS PARTICLES 有权
标题翻译：含有基因组1B的乙型肝炎病毒C型病毒基因组的核酸构建体，与其转染的丙型肝炎病毒基因组代谢细胞及其生产感染性丙型肝炎病毒颗粒的方法
公开(公告)号：US20140302082A1
公开(公告)日：2014-10-09
申请号：US14009049
申请日：2012-03-30
申请人： Takaji Wakita , Tomoko Date , Yasuhito Tanaka , Masashi Mizokami
发明人： Takaji Wakita , Tomoko Date , Yasuhito Tanaka , Masashi Mizokami
IPC分类号： C12N7/00 , C12Q1/70 , C07K16/08
CPC分类号： C12N7/00 , A61K39/00 , A61K39/12 , C07K14/005 , C07K16/082 , C07K16/109 , C12N15/86 , C12N2770/24221 , C12N2770/24222 , C12N2770/24231 , C12N2770/24234 , C12N2770/24243 , C12N2770/24251 , C12Q1/707 , C12Q2600/136 , C12Q2600/156
摘要： A subgenomic replicon RNA (nucleic acid) having an excellent autonomously replicating ability and a fullgenomic replicon RNA (nucleic acid) having an excellent autonomously replicating ability and infectious HCV particle-producing ability, each derived from a novel HCV of genotype 1b, are provided. Particularly, a subgenomic replicon RNA (nucleic acid) and a fullgenomic replicon RNA (nucleic acid), each derived from an HCV genome of the NC1 strain which is a novel HCV genotype 1b isolated from a patient with acute severe hepatitis C, are provided.
摘要翻译：提供了具有优异的自主复制能力的亚基因组复制子RNA（核酸）和具有优异的自主复制能力和感染性HCV颗粒产生能力的全基因组复制子RNA（核酸），各自源自基因型1b的新型HCV。特别地，提供了从NC1菌株的HCV基因组衍生的亚基因组复制子RNA（核酸）和全基因组复制子RNA（核酸），其是从急性重症丙型肝炎患者分离的新型HCV基因型1b。

5. 发明申请

US20110160252A1 PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OR PREVENTION OF HBV INFECTION 审中-公开
标题翻译：用于治疗或预防HBV感染的药物组合物
公开(公告)号：US20110160252A1
公开(公告)日：2011-06-30
申请号：US12999055
申请日：2009-06-18
申请人： Masashi Mizokami , Yasuhito Tanaka , Masaya Sugiyama , Masayuki Sudoh
发明人： Masashi Mizokami , Yasuhito Tanaka , Masaya Sugiyama , Masayuki Sudoh
IPC分类号： A61K31/44 , C07C229/34 , A61K31/195 , C07D213/55 , A61P31/12
CPC分类号： A61K31/13 , A61K31/165 , A61K31/201 , A61K31/381 , A61K31/405 , A61K31/4406 , A61K31/4418
摘要： First, the present inventors assessed the effect of the compound represented by formula (III) below on Huh-7 cells infected with HBV, and demonstrated that the compound alone had an anti-HBV effect in vitro.Formula (III) Then, the present inventors revealed that the HBV replication-suppressing effect of PEG-IFN is enhanced in chimeric mice having a human liver infected with genotype C or A HBV when PEG-IFN is used in combination with the compound represented by formula (III) above. The present inventors also revealed that the HBV replication-suppressing effect of Entecavir is enhanced in chimeric mice having a human liver infected with genotype C HBV (wild-type and Entecavir-resistant strains) when Entecavir is used in combination with the compound represented by formula (III) above. In addition, the present inventors revealed that the compound represented by formula (III) above exerts the anti-HBV effect not only against wild-type HBV strains but also against Entecavir- and/or Lamivudine-resistant HBV strains.
摘要翻译：首先，本发明人评估了下述式（III）表示的化合物对HBV感染的Huh-7细胞的作用，并证明该化合物在体外具有抗HBV作用。式（III）然后，本发明人揭示了当将PEG-IFN与由下列化合物组合使用时，将具有基因型C或A HBV感染的人肝的嵌合小鼠中的PEG-IFN的HBV复制抑制作用增强上述式（III）。本发明人还发现，当恩替卡韦与式（I）表示的化合物组合使用时，恩替卡韦的HBV复制抑制作用在具有感染基因型C HBV（野生型和恩替卡韦抗性菌株）的人肝脏的嵌合小鼠中得到增强（三）。此外，本发明人发现，上述式（III）表示的化合物不仅对抗野生型HBV株而且对依替卡韦和/或拉米夫定耐药的HBV株产生抗HBV作用。

6. 发明申请

US20110126791A1 EXHAUST POPPET VALVE AND SOLUTION HEAT TREATMENT METHOD OF THE SAME 有权
标题翻译：排气阀和溶液热处理方法
公开(公告)号：US20110126791A1
公开(公告)日：2011-06-02
申请号：US13055222
申请日：2008-07-25
申请人： Yasuhito Tanaka , Hisanaga Yokoyama
发明人： Yasuhito Tanaka , Hisanaga Yokoyama
IPC分类号： F01L3/02 , C21D9/00 , C21D1/00 , C21D6/00 , C22F1/10
CPC分类号： C22C38/02 , B21K1/22 , C21D1/10 , C21D1/42 , C21D6/00 , C21D9/00 , C21D2211/001 , C21D2221/00 , F01L1/0532 , F01L1/143 , F01L3/00 , F01L3/02 , F01L3/08 , F01L3/20 , F01L2101/00 , F01L2103/00 , F01L2820/01 , Y02P10/253
摘要： Object of the Invention The invention provides a forged exhaust poppet valve and a method of solution heat treating the same, in which only a predetermined portion of the valve is subjected to the solution heat treatment so as to provide the seat portion of the valve with satisfactory wear resistance, and a predetermined transitional neck-stem region with satisfactory high-temperature creep strength.Means for Achieving the Object An exhaust poppet valve (10) comprises a head portion (12) which has a seat portion (14) on the outer periphery thereof and is integral with the diametrically tapered neck portion (16) of a stem portion (18) of the valve. Using a radio-frequency heating apparatus, a solution heat treatment is given to a predetermined transitional region (A) defined between the neck and stem portions that is exposed to exhaust air during a valve opening period so that the grain size in the region (A) is controlled not to exceed ASTM 10. Thus, not only required high-temperature creep strength is secured in the transitional neck-shaft region (A) but also necessary hardness (wear resistance) is secured in the seat portion (14) of the valve (10), thereby rendering the exhaust poppet valve highly durable.
摘要翻译：发明目的本发明提供了一种锻造排气提升阀及其热处理方法，其中仅对阀的预定部分进行固溶热处理，以使阀的座部分具有令人满意的耐磨性以及具有令人满意的高温蠕变强度的预定的过渡颈部区域。用于实现对象的装置排气提升阀（10）包括头部（12），头部（12）在其外周上具有座部（14），并与杆部（18）的直径锥形颈部（16）成一体）。使用射频加热装置，在限定在颈部和茎部之间的预定过渡区域（A）进行固溶热处理，其在阀打开期间暴露于排气中，使得区域（A ）被控制为不超过ASTM 10.因此，不仅在过渡颈部轴区域（A）中确保了所需的高温蠕变强度，而且确保了必要的硬度（耐磨性）在座椅部分（14）中阀（10），从而使排气提升阀高度耐用。

7. 发明授权

US07100754B2 Pulley unit 失效
标题翻译：滑轮单元
公开(公告)号：US07100754B2
公开(公告)日：2006-09-05
申请号：US10997877
申请日：2004-11-29
申请人： Yasuhito Tanaka
发明人： Yasuhito Tanaka
IPC分类号： F16D15/00
CPC分类号： F16H55/36 , F16H2055/366
摘要： A pulley unit made by interposing a one-way clutch in an annular space between a pulley and an axial body providing a deep groove ball bearing on a base end side of the one-way clutch, and a roller bearing on the free end side; setting an inner rolling surface of a roller of the one-way clutch to be an outer diameter surface of the axial body and an inner rolling surface of a rolling member of the roller bearing to be an outer diameter surface of the axial body. The pulley unit permits easy position setting of the pulley, so that stabilized lock and free operation can be expected and productivity can be improved.
摘要翻译： 1.一种滑轮单元，其通过在单向离合器的基端侧的滑轮与轴向体之间的环形空间中插入单向离合器和在自由端侧的滚子轴承，将单向离合器的辊的内侧滚动面设定为轴向体的外径面，将滚子轴承的滚动体的内侧滚动面设定为轴向体的外径面。滑轮单元允许滑轮的容易位置设置，从而可以预期稳定的锁定和自由操作，并且可以提高生产率。

8. 发明授权

US06721238B2 Magneto-optical recording medium having multiple magnetic layers capable of reducing reproducing laser power 失效
标题翻译：具有能够减少再现激光功率的多个磁性层的磁光记录介质
公开(公告)号：US06721238B2
公开(公告)日：2004-04-13
申请号：US09996418
申请日：2001-11-29
申请人： Yasuhito Tanaka , Yoshihiro Muto
发明人： Yasuhito Tanaka , Yoshihiro Muto
IPC分类号： G11B1100
CPC分类号： G11B11/10586 , G11B11/10584 , Y10T428/1121
摘要： A magneto-optical recording medium for recording and reproducing carriers by laser beam irradiation includes a first magnetic layer which is magnetized in the in-plane direction at room temperature and is perpendicularly magnetized at a predetermined temperature T1 or more; a second magnetic layer which is in contact with the first magnetic layer, has a Curie temperature Tc2 higher than the predetermined temperature T1, and has in-plane magnetic anisotropy up to the Curie temperature Tc2; a third magnetic layer which has a Curie temperature Tc3 higher than the predetermined temperature T1 and has perpendicular magnetic anisotropy at least in a predetermined range of a temperature distribution of the magneto-optical recording medium during laser beam irradiation when reproducing; and a rare earth metal layer formed between the third magnetic layer and the second magnetic layer.
摘要翻译：用于通过激光束照射来记录和再现载体的磁光记录介质包括在室温下在面内方向被磁化并在预定温度T1或更高的温度下垂直磁化的第一磁性层; 与第一磁性层接触的第二磁性层具有高于预定温度T1的居里温度Tc2，具有高达居里温度Tc2的面内磁各向异性; 具有比预定温度T1高的居里温度Tc3的第三磁性层，并且在再现时在激光束照射期间至少在磁光记录介质的温度分布的预定范围内具有垂直的磁各向异性; 以及形成在第三磁性层和第二磁性层之间的稀土金属层。

9. 发明授权

US06207151B1 Aqueous solution of t-PA 失效
标题翻译： t-PA的水溶液
公开(公告)号：US06207151B1
公开(公告)日：2001-03-27
申请号：US08259152
申请日：1994-06-13
申请人： Yukio Shimazaki , Nobuhiro Kawashima , Miki Suzuki , Yasuhito Tanaka , Ryo Tanaka , Kiyoshi Sakai , Hisahiro Ishiwari
发明人： Yukio Shimazaki , Nobuhiro Kawashima , Miki Suzuki , Yasuhito Tanaka , Ryo Tanaka , Kiyoshi Sakai , Hisahiro Ishiwari
IPC分类号： A61K3849
CPC分类号： A61K38/49 , A61K47/34 , A61K47/36 , A61K47/42
摘要： Aqueous protein-containing solutions, in which a protein is dissolved at a high concentration at a pH near the isoelectric point of the protein by adding an anionic polymer or a salt thereof to the solution. Pharmaceutical formulations using a physiologically active protein are prepared using this technique.
摘要翻译：含有蛋白质的溶液，其中蛋白质通过向溶液中加入阴离子聚合物或其盐，在接近蛋白质等电点的pH下以高浓度溶解。使用该技术制备使用生理活性蛋白质的药物制剂。

10. 发明授权

US4965263A 6-acylaminophenyl-5-alkyl-4,5-dihydro-3(2H)-pyridazinone compounds useful as blood pressure depressants, antithrombotic agents and in the treatment of heart disease 失效
标题翻译：可用作降压药，抗血栓形成剂和治疗心脏病的6-酰基氨基苯基-5-烷基-4,5-二氢-3（2H） - 哒嗪酮化合物
公开(公告)号：US4965263A
公开(公告)日：1990-10-23
申请号：US310505
申请日：1989-02-14
申请人： Takashi Nishina , Joji Kamiya , Yasuhito Tanaka , Tsutomu Katakami , Nobuyuki Fukazawa , Hajime Iizuka , Takuo Nakano
发明人： Takashi Nishina , Joji Kamiya , Yasuhito Tanaka , Tsutomu Katakami , Nobuyuki Fukazawa , Hajime Iizuka , Takuo Nakano
IPC分类号： C07D237/04 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
CPC分类号： C07D401/12 , C07D237/04 , C07D403/12 , C07D405/12 , C07D409/12
摘要： This invention relates to pyridazinone derivatives of the general formula: ##STR1## [wherein R.sup.1 stands for a hydrogen atom or a lower alkyl group; R.sup.2 for a hydrogen atom or a lower alkyl group; and A for (i) a ring selected from a benzene ring, a furan ring, a thiophene ring and a pyridine ring (on which ring 1-3 substituents or atoms selected from amino groups, nitro groups, lower alkanoylamino groups, hydroxyl groups, lower alkanoyloxy groups, sulfamoyl groups and halogen atoms may be present), or (ii) a grouping of the formula: ##STR2## (wherein R.sup.3 stands for a hydrogen atom, a lower alkyl group, a phenyl(lower)alkyl, a hydroxyphenyl(lower)alkyl group, a lower alkylmercapto(lower)alkyl group, a benzylmercapto(lower)alkyl group, a guanidino(lower)alkyl group, a nitroguanidino(lower)alkyl group, an indolyl(lower)alkyl group, a carbamoyl(lower)alkyl group or a carboxy(lower)alkyl group, R.sup.4 for a hydrogen atom or a lower alkyl group, R.sup.5 for a hydrogen atom, a lower alkyl group, a lower alkanoyl group, a benzoyl or a benzyloxycarbonyl group, and R.sup.3 and R.sup.4 may be combined to form a grouping of the formula: ##STR3## which forms a ring), or (iii) a grouping of the formula: ##STR4## (wherein R.sup.6, R.sup.7 and R.sup.8 each stand for a hydrogen atom or a lower alkyl group, B is an oxygen atom or a sulfur atom, R.sup.9 stands for a hydrogen atom or a lower alkanoyl group, and n is 0 or 1)].

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