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1. 发明授权

US4763535A Pipette mechanism 失效
标题翻译：移液器机构
公开(公告)号：US4763535A
公开(公告)日：1988-08-16
申请号：US004864
申请日：1987-01-20
申请人： Kenneth Rainin , Haakon T. Magnussen, Jr. , Roy P. Moeller
发明人： Kenneth Rainin , Haakon T. Magnussen, Jr. , Roy P. Moeller
IPC分类号： B01L3/02 , G01N1/14
CPC分类号： B01L3/0224
摘要： A dashpot piston mounted in a closed chamber is coupled by an axially movable shaft to a pipette piston to regulate return movement of the pipette piston within a pipette cylinder to draw fluid into the cylinder. The dashpot shaft is movable within limits relative to the dashpot piston to accommodate a blow-out of residual fluid from the pipette by the shaft driving the pipette piston beyond a home position to blow residual fluid from the pipette cylinder. An air inlet port in the bottom of the chamber allows air to be drawn into the chamber with upward movement of the dashpot piston while a valve adjacent to the air inlet port opens in response to downward movement of the dashpot piston to exit air from the chamber. Control of the relative sizes of the air inlet port and valve outlet regulates the relative rates of upward and downward piston movement in the cylinder. The dashpot piston carries a movable plate of a variable capacitor transducer for monitoring the position of the pipette piston within the pipette cylinder.
摘要翻译：安装在封闭室中的缓冲器活塞通过可轴向移动的轴联接到移液管活塞，以调节移液管活塞在移液管气缸内的返回运动，以将流体吸入气缸。缓冲器轴可相对于缓冲器活塞在极限内移动，以通过驱动移液管活塞的轴超过原始位置来容纳来自移液管的剩余流体的吹出，以吹送来自移液管的残余流体。在室的底部的空气入口允许空气随着缓冲器活塞的向上运动而被吸入室中，同时与空气入口相邻的阀响应于缓冲器活塞向下移动以从腔室排出空气而打开。控制进气口和阀门出口的相对尺寸可调节气缸中上下活塞运动的相对速率。缓冲器活塞承载可变电容换能器的可移动板，用于监测移液管活塞在移液管内的位置。

2. 发明授权

US5779984A Pipette tip rack and refill pack containing large maximized volume freely nestable pipette tips 失效
标题翻译：移液器支架和充填包，其中包含大的最大体积可自由嵌套的移液器吸头
公开(公告)号：US5779984A
公开(公告)日：1998-07-14
申请号：US759409
申请日：1996-12-04
申请人： Christopher Kelly , David J. Lemieux , Haakon T. Magnussen, Jr. , James S. Petrek , Kenneth Rainin
发明人： Christopher Kelly , David J. Lemieux , Haakon T. Magnussen, Jr. , James S. Petrek , Kenneth Rainin
IPC分类号： B01L9/00 , B65D25/10 , B01L3/02 , B65D85/00
CPC分类号： B01L9/543 , B65D25/108
摘要： A plurality of large maximized internal volume freely nestable pipette tips for mounting in a standard pipette tip rack or refill pack including a horizontally extending pipette tip support having a plurality of through holes arranged in an array, each hole having a center which is spaced a distance "s" from centers of immediately adjacent through holes, each pipette tip having a substantially cylindrical proximal portion and an elongated generally conical distal portion coaxial with and joined to its proximal portion adjacent a downward facing outwardly extending shoulder and including at a distal end of the tip a relatively small orifice for receiving and dispensing fluid into and from the pipette tip upon operation of a pipette to which the pipette tip is mounted, the proximal portion of each pipette tip having an outer diameter equal to or slightly less than "s" and a slightly conical inner surface for tightly receiving and releasably attaching to a pipette tip mounting shaft of a large volume pipette and the distal portion of each pipette tip in a first array of tips being vertically oriented in a different one of the through holes in the support with its shoulder on a top of the support.
摘要翻译：多个大的最大化的内部体积可自由嵌套的移液管尖端，用于安装在标准移液管末端架或补充包中，其包括具有排列成阵列的多个通孔的水平延伸的移液管末梢支撑件，每个孔具有间隔一定距离的中心 “s”从紧邻的通孔的中心，每个移液管尖端具有基本上圆柱形的近端部分和细长的大致圆锥形的远端部分，该近端部分与其近端部分同轴并连接到邻近向下的向外延伸的肩部并且包括在远端在操作移液管尖端安装移液管的操作时，将一个相当小的孔用于接收和分配流体和/或从移液管尖端分配流体，每个移液管尖端的近端部分具有等于或略小于“s”的外径，一个稍微锥形的内表面，用于紧密地接收和可释放地附接到a的移液管尖端安装轴大体积移液管，并且第一阵列尖端中的每个移液管尖端的远端部分垂直地定向在支撑件中的不同的一个通孔中，其肩部位于支撑件的顶部上。

3. 发明授权

US5364596A Manual pipette with plunger velocity governor, home position latch and trigger release 失效
标题翻译：带柱塞速度调节器的手动移液器，原点位置锁定和触发释放
公开(公告)号：US5364596A
公开(公告)日：1994-11-15
申请号：US983883
申请日：1992-12-01
申请人： Haakon T. Magnussen, Jr. , William D. Homberg , Kenneth Rainin
发明人： Haakon T. Magnussen, Jr. , William D. Homberg , Kenneth Rainin
IPC分类号： B01L3/02 , G01N1/14
CPC分类号： B01L3/0224
摘要： A manual pipette including user controllable latch and trigger mechanisms for releasably locking the plunger of the pipette in a "home" position ready for immersion of the pipette tip in a fluid to be drawn into the tip and further including a user controllable velocity governor for regulating the rate of plunger return from the "home" position to a first or upper stop position in drawing the fluid into the tip.
摘要翻译：手动移液器，其包括用户可控制的闩锁和触发机构，用于将移液管的柱塞可释放地锁定在“本地”位置，准备将移液管尖端浸入待吸入尖端的流体中，并且还包括用户可控制的调速器，在将流体引入尖端时，柱塞从“主”位置返回到第一或上停止位置的速率。

4. 发明授权

US06428750B1 Volume adjustable manual pipette with quick set volume adjustment 有权
标题翻译：体积可调式手动移液器，可快速设定音量调节
公开(公告)号：US06428750B1
公开(公告)日：2002-08-06
申请号：US09548439
申请日：2000-04-13
申请人： Kenneth Rainin , Haakon T. Magnussen, Jr. , Phillip Yee , William D. Homberg , James S. Petrek
发明人： Kenneth Rainin , Haakon T. Magnussen, Jr. , Phillip Yee , William D. Homberg , James S. Petrek
IPC分类号： B01L302
CPC分类号： B01L3/0224 , Y10T436/2575
摘要： A volume adjustable manual pipette having a hand-holdable housing supporting (i) an electronic digital display and associated position sensing and control circuitry, (ii) a plunger unit and (iii) a quick set volume adjustment mechanism for simultaneously controlling the volume setting of the pipette and the electronic display, the quick set volume adjustment mechanism comprising a pipette volume setting member for limiting upward movement of the plunger unit within the housing to define the volume setting for the pipette and the volume setting member being supported for axial movement on the plunger unit and releasably secured relative to the housing by a pipette user operable locking mechanism. When released from the housing, the volume setting member is axially moveable on and with the plunger unit to quickly set the volume for the pipette. When secured to the housing, the plunger unit is axially moveable relative to the volume setting unit to aspirate and dispense the selected volume of liquid into and from a pipette tip extending from a lower end of the housing. The volume setting of the pipette is monitored by the sensing and control circuitry to provide a real time display of the volume setting of the pipette.
摘要翻译：一种体积可调节的手动移液器，其具有可手持的壳体，其支撑（i）电子数字显示器和相关联的位置感测和控制电路，（ii）柱塞单元和（iii）快速设定体积调节机构，用于同时控制移液管和电子显示器，快速设定的体积调节机构包括用于限制柱塞单元在壳体内的向上运动的移液管体积调节构件，以限定用于移液管的体积设置，并且容积设定构件被支撑以在柱塞单元，并通过移液管用户可操作的锁定机构相对于壳体可释放地固定。当从壳体释放时，体积调节构件可以在柱塞单元上和与柱塞单元一起轴向移动以快速设定移液管的体积。当固定到壳体时，柱塞单元相对于体积设定单元轴向移动，以将选定体积的液体吸入并分配到从壳体的下端延伸的移液管尖端和从其移出。移液器的体积设置由感测和控制电路监控，以提供移液器的体积设置的实时显示。

5. 发明授权

US5392914A Refill pack for pipette tip racks 失效
标题翻译：移液器吸头架的补充包装
公开(公告)号：US5392914A
公开(公告)日：1995-02-28
申请号：US124966
申请日：1993-09-21
申请人： David J. Lemieux , Paul K. Chadwick , Christopher Kelly , James S. Petrek , Kenneth Rainin , Haakon T. Magnussen, Jr. , William D. Homberg
发明人： David J. Lemieux , Paul K. Chadwick , Christopher Kelly , James S. Petrek , Kenneth Rainin , Haakon T. Magnussen, Jr. , William D. Homberg
IPC分类号： B01L9/00 , B65D71/70 , B65D85/30 , B01L3/02 , B65D21/00
CPC分类号： B65D71/70 , B01L9/543 , Y02W30/807
摘要： A refill pack of light weight low mass material containing an array of replacement pipette tips for a reusable tip rack. The refill pack comprises a support plate with an array of holes containing pipette tips arranged in an organized manner and including a skirt-like guide for centering and guiding the support plate onto the tip rack with distal end portions of the pipette tips aligned with and vertically entering corresponding holes in an organizing tray in the tip rack.
摘要翻译：一个重量轻的低质量材料的补充包装，包含可重复使用的顶架的更换移液器吸头阵列。所述补充组件包括具有排列孔的支撑板，所述支撑板包括以有组织的方式布置的移液管末端，并且包括裙状引导件，用于将所述支撑板定心并引导到所述末端齿条上，所述移液管尖端的远端部分与所述对准进入针架的组织托盘中相应的孔。

6. 发明授权

US5792424A Manual pipette with delayed-action home position latch 失效
标题翻译：手动移液器，带有延迟动作原位置锁存器
公开(公告)号：US5792424A
公开(公告)日：1998-08-11
申请号：US658862
申请日：1996-08-15
申请人： William D. Homberg , Christopher Kelly , Kenneth Rainin , Haakon T. Magnussen, Jr.
发明人： William D. Homberg , Christopher Kelly , Kenneth Rainin , Haakon T. Magnussen, Jr.
IPC分类号： B01L3/02 , G01N1/14
CPC分类号： B01L3/0224 , B01L2300/026 , Y10T436/2575
摘要： A manual pipette including a delayed action home position latch for engaging only after the plunger unit of the pipette has moved downward through its home position to thereafter releasably connect a moveable bottom stop member to the plunger unit to move therewith and upon an upward return of the plunger unit by the pipette's return spring to engage a home position stop to releasably lock the plunger unit in its home position without any downward force being exerted by the pipette user on the plunger unit.
摘要翻译：手动移液器包括用于仅在移液管的柱塞单元之后接合的延迟动作原位锁定器已经向下移动通过其原始位置，此后将可移动的底部止动构件可释放地连接到柱塞单元以随之移动，并且在向上返回时柱塞单元通过移液管的复位弹簧接合原位置止动件以可释放地将柱塞单元锁定在其原始位置，而没有由移液管使用者施加在柱塞单元上的任何向下的力。

7. 发明授权

US5441702A Refill pack for pipette tip racks 失效
标题翻译：移液器吸头架的补充包装
公开(公告)号：US5441702A
公开(公告)日：1995-08-15
申请号：US125019
申请日：1993-09-21
申请人： David J. Lemieux , Paul K. Chadwick , Christopher Kelly , James S. Petrek , Kenneth Rainin , Haakon T. Magnussen, Jr. , William D. Homberg
发明人： David J. Lemieux , Paul K. Chadwick , Christopher Kelly , James S. Petrek , Kenneth Rainin , Haakon T. Magnussen, Jr. , William D. Homberg
IPC分类号： B01L9/00 , B65D71/70 , B01L3/02 , B65D1/34 , B65D55/00
CPC分类号： B65D71/70 , B01L9/543
摘要： A refill pack for storing and dispensing pipette tips into a tip rack, comprising a support plate with an array of holes containing disposable pipette tips arranged in an organized array and a carrier for hand positioning the support plate over the tip rack for release of the array of pipette tips into the tip rack.
摘要翻译：一种用于将移液管尖端存储并分配到尖端架中的补充包，包括具有排列成有组织阵列的一次性移液管尖端的孔阵列的支撑板和用于将支撑板手指定位在尖端齿条上用于释放阵列的载体的移液器尖端进入尖端架。

8. 发明授权

US06352673B1 Ergonomic return springless manual air displacement pipette 失效
标题翻译：人体工程学返回无弹簧手动排气移液器
公开(公告)号：US06352673B1
公开(公告)日：2002-03-05
申请号：US09522257
申请日：2000-03-09
申请人： Kenneth Rainin , William D. Homberg
发明人： Kenneth Rainin , William D. Homberg
IPC分类号： B01L302
CPC分类号： B01L3/0286 , B01L3/0217 , B01L2200/087
摘要： An ergonomic, manually precisely controllable return springless air displacement pipette relying on the friction of a piston seal to maintain a plunger unit of the pipette in any axial location established by a user of the pipette.
摘要翻译：符合人体工程学的手动精确可控的回弹弹簧空气移位移液管依靠活塞密封件的摩擦力将移液器的柱塞单元保持在由移液器的使用者建立的任何轴向位置。

9. 发明授权

US4779467A Liquid-end assembly for multichannel air-displacement pipette 失效
标题翻译：液体端组件用于多通道空气移液移液器
公开(公告)号：US4779467A
公开(公告)日：1988-10-25
申请号：US8217
申请日：1987-01-28
申请人： Kenneth Rainin , Walter S. Watson
发明人： Kenneth Rainin , Walter S. Watson
IPC分类号： B01L3/02 , G01N35/10
CPC分类号： B01L3/0279 , G01N35/1065
摘要： A multichannel air-displacement pipette liquid-end assembly having a modular construction, which enables individual components to be easily replaced when they become contaminated or worn. The modular liquid-end assembly also enables selected piston and cylinder components to be selectively removed so that any one of a number of predetermined multichannel pipetting configurations can be employed. Additionally, the modular liquid-end assembly preferably comprises an ejector for providing low-friction mechanical advantage in order to facilitate dislodging spent tips.
摘要翻译：具有模块化结构的多通道空气移液移液器液体端组件，其能够在被污染或磨损时容易地更换各个部件。模块化液体端组件还使选择的活塞和气缸部件能够被选择性地移除，使得可以采用多种预定的多通道移液结构中的任何一种。此外，模块化液体端部组件优选地包括用于提供低摩擦机械优点的喷射器，以便于消除耗尽的尖端。

10. 发明授权

US4551249A Modular liquid chromatography column apparatus 失效
公开(公告)号：US4551249A
公开(公告)日：1985-11-05
申请号：US584611
申请日：1984-02-29
申请人： Carl L. Shackelford , Kenneth Rainin
发明人： Carl L. Shackelford , Kenneth Rainin
IPC分类号： B01D15/08 , G01N30/52 , G01N30/56 , G01N30/60
CPC分类号： G01N30/56 , G01N30/6021 , G01N30/6026 , G01N30/6039 , G01N2030/522 , G01N30/6004 , G01N30/6017
摘要： A chromatography column apparatus which utilizes sorbant material in a tube which has a first and second end portion. The first end portion of the tube includes a plug having a passage through the same. The plug fits in the same, adjacent the sorbant material, and is movable within the tube. An end fitting is also employed which has a portion that is placed within the tube adjacent the plug. The end fitting has a passage therethrough which communicates with the passage of the plug. A seal is used inside the tube between the plug and the end fitting. The end fitting and plug are held together. The second end portion of the tube is enclosed and also includes a passage from the interior to the exterior of the tube.

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