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1. 发明申请

US20070016260A1 Reduction of left-ventricular offset interaction with tachyarrhythmia detection 有权
标题翻译：减慢与心律失常检测的左心室偏移相互作用
公开(公告)号：US20070016260A1
公开(公告)日：2007-01-18
申请号：US11522691
申请日：2006-09-18
申请人： Kenneth Baker , David Perschbacher , Andrew Kramer , Jeffrey Stahmann
发明人： Kenneth Baker , David Perschbacher , Andrew Kramer , Jeffrey Stahmann
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.
摘要翻译：通过向两个心室分配指定的偏移间隔来逐步重新同步心室，从而改善快速性心律失常检测的装置和方法。逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。提供回波起搏模式，以便当速率心室在另一脑室之后起搏时，防止快速性心律失常检测受到损害。

2. 发明申请

US20060271108A1 Safety control system for implantable neural stimulator 有权
公开(公告)号：US20060271108A1
公开(公告)日：2006-11-30
申请号：US11135883
申请日：2005-05-24
申请人： Imad Libbus , Andrew Kramer , William Linder , Jeffrey Stahmann
发明人： Imad Libbus , Andrew Kramer , William Linder , Jeffrey Stahmann
IPC分类号： A61N1/36
CPC分类号： A61N1/36142 , A61N1/36114 , A61N1/36139 , A61N1/37
摘要： A neural stimulation system includes a safety control system that prevents delivery of neural stimulation pulses from causing potentially harmful effects. The neural stimulation pulses are delivered to one or more nerves to control the physiological functions regulated by the one or more nerves. Examples of such harmful effects include unintended effects in physiological functions associated with autonomic neural stimulation and nerve injuries caused by excessive delivery of the neural stimulation pulses.

3. 发明申请

US20060052830A1 Cardiac rhythm management system with arrhythmia classification and electrode selection 有权
公开(公告)号：US20060052830A1
公开(公告)日：2006-03-09
申请号：US11268284
申请日：2005-11-03
申请人： Julio Spinelli , Qingsheng Zhu , Jeffrey Stahmann , Andrew Kramer
发明人： Julio Spinelli , Qingsheng Zhu , Jeffrey Stahmann , Andrew Kramer
IPC分类号： A61N1/39
CPC分类号： A61N1/3622 , A61N1/3684
摘要： A system, method, or device classifies an arrhythmia according to the temporal order in which a depolarization wave associated with a particular heart contraction is received at a plurality of electrodes. One or more antiarrhythmia therapies is mapped to each arrhythmia classification. When a particularly classified arrhythmia is detected, the correspondingly mapped therapy list is selected and an appropriate antiarrhythmia therapy delivered. In one example, the particular therapy delivered in response to an arrhythmia depends at least in part on its historical success in treating arrhythmias of that classification.

4. 发明申请

US20060004418A1 System and method for managing refractory periods in a cardiac rhythm management device with biventricular sensing 有权
$System and method for managing refractory periods in a cardiac rhythm management device with biventricular sensing$
公开(公告)号：US20060004418A1
公开(公告)日：2006-01-05
申请号：US11218865
申请日：2005-09-02
申请人： Jeffrey Stahmann , Andrew Kramer , James Gilkerson , Lorenzo DiCarlo , Rene Wentkowski
发明人： Jeffrey Stahmann , Andrew Kramer , James Gilkerson , Lorenzo DiCarlo , Rene Wentkowski
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/3684
摘要： A method and system for managing refractory periods in a cardiac rhythm management device configured for biventricular or biatrial sensing. Refractory periods for each channel of the pacemaker are provided by interval timers that are triggered by sensed or paced events in order to prevent misinterpretation of sensing signals.

5. 发明申请

US20050228454A1 Trending of conduction time for optimization of cardiac resynchronization therapy in cardiac rhythm management system 有权
公开(公告)号：US20050228454A1
公开(公告)日：2005-10-13
申请号：US11142165
申请日：2005-06-01
申请人： Andrew Kramer , Jeffrey Stahmann , Veerichetty Kadhiresan
发明人： Andrew Kramer , Jeffrey Stahmann , Veerichetty Kadhiresan
IPC分类号： A61N1/362 , A61N1/365 , A61N1/368
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/36542 , A61N1/3682 , A61N1/3684
摘要： A method of optimizing cardiac resynchronization therapy delay over a patient's full range of activity for use in operating an implantable cardiac pacing device and such a device are disclosed. The method includes measuring selected conduction time between selected sites in the heart for a plurality of beats and logging the values on a periodic repeating programmable basis to produce cumulative data and constructing a current template of conduction time in relation to one or more other sensed parameters of interest over a desired range of patient activity levels. The current template is used to derive suggested optimum pacing timing.

6. 发明申请

US20050004606A1 Safety pacing in multi-site CRM devices 有权
标题翻译：多站点CRM设备中的安全起搏
公开(公告)号：US20050004606A1
公开(公告)日：2005-01-06
申请号：US10839268
申请日：2004-05-05
申请人： Jeffrey Stahmann , Andrew Kramer , Hugh Calkins
发明人： Jeffrey Stahmann , Andrew Kramer , Hugh Calkins
IPC分类号： A61N1/362
CPC分类号： A61N1/368 , A61N1/3622 , A61N1/3627 , A61N1/3684
摘要： Safety pacing in multi-site cardiac rhythm management (CRM) devices is provided. According to various method embodiments, a first cardiac signal from a first cardiac region and a second cardiac signal from a second cardiac region are sensed. The first cardiac region is paced to maintain at least a minimum cardiac rate, and the second cardiac region is paced to maintain at least the minimum cardiac rate when a pace in the first cardiac region is inhibited. Other aspects and embodiments are provided herein.
摘要翻译：提供了多站点心律管理（CRM）设备中的安全起搏。根据各种方法实施例，感测来自第一心脏区域的第一心脏信号和来自第二心脏区域的第二心脏信号。第一心脏区域起搏以保持至少最小心率，并且当第一心脏区域中的步调被抑制时，第二心脏区域起搏以保持至少最小心率。本文提供了其它方面和实施例。

7. 发明申请

US20060293714A1 Method and apparatus for controlling cardiac therapy based on electromechanical timing 有权
标题翻译：基于机电定时控制心脏治疗的方法和装置
公开(公告)号：US20060293714A1
公开(公告)日：2006-12-28
申请号：US11168024
申请日：2005-06-28
申请人： Rodney Salo , Joseph Pastore , Andrew Kramer , Jeffrey Stahmann , Jesse Hartley
发明人： Rodney Salo , Joseph Pastore , Andrew Kramer , Jeffrey Stahmann , Jesse Hartley
IPC分类号： A61N1/36
CPC分类号： A61N1/3627 , A61M5/14276 , A61N1/36521 , A61N1/36585 , A61N1/3756
摘要： Devices and methods for therapy control based on electromechanical timing involve detecting electrical activation of a patient's heart, and detecting mechanical cardiac activity resulting from the electrical activation. A timing relationship is determined between the electrical activation and the mechanical activity. A therapy is controlled based on the timing relationship. The therapy may improve intraventricular dyssynchrony of the patient's heart, or treat at least one of diastolic and systolic dysfunction and/or dyssynchrony of the patient's heart, for example. Electrical activation may be detected by sensing delivery of an electrical stimulation pulse to the heart or sensing intrinsic depolarization of the patient's heart. Mechanical activity may be detected by sensing heart sounds, a change in one or more of left ventricular impedance, ventricular pressure, right ventricular pressure, left atrial pressure, right atrial pressure, systemic arterial pressure and pulmonary artery pressure.
摘要翻译：基于机电定时的治疗控制的装置和方法涉及检测患者心脏的电激活，以及检测由电激活引起的机械心脏活动。在电激活和机械活动之间确定时序关系。基于时间关系控制治疗。该治疗可以改善患者心脏的心室内不同步，或治疗患者心脏的舒张期和收缩功能障碍和/或不同步中的至少一种。可以通过感测向心脏传递电刺激脉冲或感测患者心脏的固有去极化来检测电激活。可以通过感测心脏声音，左心室阻抗，心室压力，右心室压力，左心房压力，右心房压力，全身动脉压力和肺动脉压力中的一个或多个的变化来检测机械活动。

8. 发明申请

US20060116728A1 REDUCTION OF INTERACTION WITH TACHYARRHYTHMIA DETECTION BY NEGATIVE OFFSET PACING 有权
标题翻译：减少与负面偏差相关的TACHYARRHYTHMIA检测
公开(公告)号：US20060116728A1
公开(公告)日：2006-06-01
申请号：US11276031
申请日：2006-02-10
申请人： Jeffrey Stahmann , Andrew Kramer , Julio Spinelli
发明人： Jeffrey Stahmann , Andrew Kramer , Julio Spinelli
IPC分类号： A61N1/36
CPC分类号： A61N1/3622
摘要： A device and method is disclosed for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified negative offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. Techniques are presented for preventing tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.
摘要翻译：公开了一种用于改善心律失常检测的装置和方法，当通过将指定的负偏移间隔分开的两个心室递送步调来再同步时，心律失常检测。逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。提出技术用于在速率心室在另一脑室之后起搏时预防快速性心律失常检测受到损害。

9. 发明申请

US20050256547A1 Site reversion in cardiac rhythm management 审中-公开
公开(公告)号：US20050256547A1
公开(公告)日：2005-11-17
申请号：US11187278
申请日：2005-07-22
申请人： Jeffrey Stahmann , Andrew Kramer
发明人： Jeffrey Stahmann , Andrew Kramer
IPC分类号： A61N1/08 , A61N1/362 , A61N1/37
CPC分类号： A61N1/3706 , A61N1/3627 , A61N2001/083
摘要： Methods for failure recovery in a cardiac rhythm management system and apparatus capable of carrying out the methods. The methods include applying a first pacing therapy using one or more leads. The methods further include detecting a failure condition on one or more of the leads, wherein the failure condition prohibits or frustrates application of the first pacing therapy. The methods still further include applying a second pacing therapy using one or more of the leads subsequent to detecting the failure condition. The second pacing therapy is preferably chosen such that the detected failure does not interfere with the second pacing therapy. The second pacing therapy may be applied for only one cardiac cycle. The second pacing therapy may further be applied continuously until the failure condition is resolved, or it may be latched such that physician intervention is required to resume the first pacing therapy.

10. 发明申请

US20050228455A1 Trending of conduction time for optimization of cardiac resynchronization therapy in cardiac rhythm management system 审中-公开
公开(公告)号：US20050228455A1
公开(公告)日：2005-10-13
申请号：US11149107
申请日：2005-06-09
申请人： Andrew Kramer , Jeffrey Stahmann , Veerichetty Kadhiresan
发明人： Andrew Kramer , Jeffrey Stahmann , Veerichetty Kadhiresan
IPC分类号： A61N1/362 , A61N1/365 , A61N1/368 , A61N1/372
CPC分类号： A61N1/3627 , A61N1/36521 , A61N1/36542 , A61N1/3682 , A61N1/3684
摘要： A method of optimizing cardiac resynchronization therapy delay over a patient's full range of activity for use in operating an implantable cardiac pacing device and such a device are disclosed. The method includes measuring selected conduction time between selected sites in the heart for a plurality of beats and logging the values on a periodic repeating programmable basis to produce cumulative data and constructing a current template of conduction time in relation to one or more other sensed parameters of interest over a desired range of patient activity levels. The current template is used to derive suggested optimum pacing timing.

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