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1. 发明授权

US07117867B2 Aerosol generator and methods of making and using an aerosol generator 有权
公开(公告)号：US07117867B2
公开(公告)日：2006-10-10
申请号：US10438329
申请日：2003-05-15
申请人： Kenneth A. Cox , Timothy Paul Beane , William R. Sweeney , Walter A. Nichols , F. Murphy Sprinkel, Jr.
发明人： Kenneth A. Cox , Timothy Paul Beane , William R. Sweeney , Walter A. Nichols , F. Murphy Sprinkel, Jr.
IPC分类号： A61M11/00 , A61M15/00 , A61M16/00 , F16K11/00
CPC分类号： A61M15/008 , A24F47/008 , A61M11/007 , A61M11/042 , A61M15/0003 , A61M15/0066 , A61M15/0083 , A61M2016/0039 , A61M2205/10 , A61M2205/3561 , A61M2205/3653 , A61M2205/50 , A61M2205/52 , A61M2205/8225
摘要： An aerosol generator includes a flow passage having an inlet and an outlet, a heater arranged relative to the flow passage for heating the flow passage, a source of material to be volatilized in communication with the inlet of the flow passage, a valve to open and close communication between the source of material and the inlet of the flow passage, and a pressurization arrangement for causing material in the source of material to be introduced into the flow passage when the valve is in an open position. The aerosol generator further includes a source of power for operating the heater and the valve, and a control device for controlling supply of power from the source of power to the heater and the valve. A metering device in an inhaler includes a pressurized source of medicated fluid and a metering chamber configured to deliver a predetermined volume of fluid to a heated flow passage in the inhaler. The metering chamber can be part of a rotary valve having a bore and a displacement member moveable within the bore from a first position where the fluid is loaded into the bore to a second position where the predetermined volume is ejected out of the bore. Another metering chamber has an elastic portion of a delivery passage in fluid communication with the pressurized source of liquid and the elastic portion of the delivery passage is deformed to eject the predetermined volume.

2. 发明授权

US06516796B1 Aerosol generator and methods of making and using an aerosol generator 有权
标题翻译：气溶胶发生器和制造和使用气溶胶发生器的方法
公开(公告)号：US06516796B1
公开(公告)日：2003-02-11
申请号：US09479597
申请日：2000-01-07
申请人： Kenneth A. Cox , Timothy Paul Beane , William R. Sweeney , Walter A. Nichols , F. Murphy Sprinkel, Jr.
发明人： Kenneth A. Cox , Timothy Paul Beane , William R. Sweeney , Walter A. Nichols , F. Murphy Sprinkel, Jr.
IPC分类号： A61M1100
CPC分类号： A61M15/008 , A24F47/008 , A61M11/007 , A61M11/042 , A61M15/0003 , A61M15/0066 , A61M15/0083 , A61M2016/0039 , A61M2205/10 , A61M2205/3561 , A61M2205/3653 , A61M2205/50 , A61M2205/52 , A61M2205/8225
摘要： An aerosol generator includes a flow passage having an inlet and an outlet, a heater arranged relative to the flow passage for heating the flow passage, a source of material to be volatilized in communication with the inlet of the flow passage, a valve to open and close communication between the source of material and the inlet of the flow passage, and a pressurization arrangement for causing material in the source of material to be introduced into the flow passage when the valve is in an open position. The aerosol generator further includes a source of power for operating the heater and the valve, and a control device for controlling supply of power from the source of power to the heater and the valve. A metering device in an inhaler includes a pressurized source of medicated fluid and a metering chamber configured to deliver a predetermined volume of fluid to a heated flow passage in the inhaler. The metering chamber can be part of a rotary valve having a bore and a displacement member moveable within the bore from a first position where the fluid is loaded into the bore to a second position where the predetermined volume is ejected out of the bore. Another metering chamber has an elastic portion of a delivery passage in fluid communication with the pressurized source of liquid and the elastic portion of the delivery passage is deformed to eject the predetermined volume.
摘要翻译：气雾发生器包括具有入口和出口的流动通道，相对于流道设置的加热流道的加热器，与流动通道的入口连通的待挥发的材料源，打开的阀和材料源与流路入口之间的紧密连通，以及用于当阀处于打开位置时将材料源中的材料引入流路的加压装置。气溶胶发生器还包括用于操作加热器和阀的动力源，以及用于控制从动力源到加热器和阀的动力供应的控制装置。吸入器中的计量装置包括加压的药液源和配置成将预定体积的流体输送到吸入器中的加热流动通道的计量腔。计量室可以是具有孔的旋转阀的一部分，以及位于孔内的位移元件，该位移元件从第一位置移动到第二位置，在第一位置，流体被加载到孔中到第二位置，其中预定的体积被排出孔。另一个计量室具有与加压液体流体连通的输送通道的弹性部分，并且输送通道的弹性部分变形以排出预定体积。

3. 发明授权

US07173222B2 Aerosol generator having temperature controlled heating zone and method of use thereof 有权
标题翻译：具有温度控制加热区的气溶胶发生器及其使用方法
公开(公告)号：US07173222B2
公开(公告)日：2007-02-06
申请号：US10279035
申请日：2002-10-24
申请人： Kenneth A. Cox , Walter A. Nichols , F. Murphy Sprinkel, Jr. , Douglas D. McRae , William R. Sweeney
发明人： Kenneth A. Cox , Walter A. Nichols , F. Murphy Sprinkel, Jr. , Douglas D. McRae , William R. Sweeney
IPC分类号： A05B1/02
CPC分类号： A61M11/041 , A61M11/007 , A61M11/042 , A61M15/025 , A61M2205/3372
摘要： A temperature and flow rate controlled capillary aerosol generator includes two heating zones optionally separated by a region in which a pressure drop is induced. Power is metered or applied to the downstream, second zone to achieve a target resistance, and therefore a target temperature, while power is metered or applied to the upstream, first zone to achieve a target mass flow rate exiting the second zone. A target temperature is achieved in the second zone to generate an aerosol from the liquid flowing through the generator at the desired mass flow rate.
摘要翻译：温度和流速控制的毛细管气溶胶发生器包括两个加热区，任选地由诱导压降的区域分开。将功率计量或施加到下游的第二区域以实现目标电阻，并因此实现目标温度，同时计量或施加功率到上游第一区域以实现离开第二区域的目标质量流量。在第二区域中实现目标温度，以期望的质量流率从流过发生器的液体产生气溶胶。

4. 发明授权

US06501052B2 Aerosol generator having multiple heating zones and methods of use thereof 有权
标题翻译：具有多个加热区域的气溶胶发生器及其使用方法
公开(公告)号：US06501052B2
公开(公告)日：2002-12-31
申请号：US09742322
申请日：2000-12-22
申请人： Kenneth A. Cox , Walter A. Nichols , F. Murphy Sprinkel, Jr. , Douglas D. McRae , William R. Sweeney
发明人： Kenneth A. Cox , Walter A. Nichols , F. Murphy Sprinkel, Jr. , Douglas D. McRae , William R. Sweeney
IPC分类号： H05B102
CPC分类号： A61M11/041 , A61M11/007 , A61M11/042 , A61M15/025 , A61M2205/3372
摘要： A temperature and flow rate controlled capillary aerosol generator includes two heating zones optionally separated by a region in which a pressure drop is induced. Power is metered or applied to the downstream, second zone to achieve a target resistance, and therefore a target temperature, while power is metered or applied to the upstream, first zone to achieve a target mass flow rate exiting the second zone. A target temperature is achieved in the second zone to generate an aerosol from the liquid flowing through the generator at the desired mass flow rate.
摘要翻译：温度和流速控制的毛细管气溶胶发生器包括两个加热区，任选地由诱导压降的区域分开。将功率计量或施加到下游的第二区域以实现目标电阻，并因此实现目标温度，同时计量或施加功率到上游第一区域以实现离开第二区域的目标质量流量。在第二区域中实现目标温度，以期望的质量流率从流过发生器的液体产生气溶胶。

5. 发明授权

US06701921B2 Aerosol generator having heater in multilayered composite and method of use thereof 有权
公开(公告)号：US06701921B2
公开(公告)日：2004-03-09
申请号：US09742320
申请日：2000-12-22
申请人： F. Murphy Sprinkel, Jr. , Walter A. Nichols , Kenneth A. Cox , Timothy S. Sherwood , Scott A. Sowers , Zelita R. Washington , Sirisha Reddy
发明人： F. Murphy Sprinkel, Jr. , Walter A. Nichols , Kenneth A. Cox , Timothy S. Sherwood , Scott A. Sowers , Zelita R. Washington , Sirisha Reddy
IPC分类号： A61M1600
CPC分类号： A61M15/0065 , A61M11/041 , A61M11/044 , A61M2016/0021 , A61M2205/123 , A61M2205/128 , A61M2205/3653 , A61M2205/8206
摘要： An aerosol generator includes a fluid passage arranged between a first and a second layer wherein the first and second layers at least partially define the fluid passage. A liquid supply is arranged to provide a fluid in liquid phase to the fluid passage. The aerosol generator also includes a heater arranged to volatilize the fluid in the fluid passage. An outlet of the aerosol generator is arranged to receive the volatilized fluid and direct the volatilized fluid out of the fluid passage. The aerosol generator can be used to generate aerosols containing medicated materials.

6. 发明授权

US06804458B2 Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate 有权
标题翻译：具有加热器的气溶胶发生器，其布置成在层压体的接合层之间的流体通道中蒸发流体
公开(公告)号：US06804458B2
公开(公告)日：2004-10-12
申请号：US10003852
申请日：2001-12-06
申请人： Timothy S. Sherwood , Scott A. Sowers , Sirisha P. Reddy , F. Murphy Sprinkel, Jr. , Kenneth A. Cox , Walter A. Nichols
发明人： Timothy S. Sherwood , Scott A. Sowers , Sirisha P. Reddy , F. Murphy Sprinkel, Jr. , Kenneth A. Cox , Walter A. Nichols
IPC分类号： F22B3506
CPC分类号： A61M11/041 , A61M11/007 , A61M11/042 , A61M15/00 , A61M15/025 , B05B17/04
摘要： An aerosol generator includes a fluid supply which supplies fluid to a fluid passage and a heater which heats the fluid into a gaseous state, the fluid passage being located between opposed layers of a laminate. The fluid passage can be a capillary sized passage formed by locating a mandrel between opposed layers of the laminate, bonding the layers together and removing the mandrel such that the space previously occupied by the mandrel forms the fluid passage. The opposed layers of the laminate can be copper sheets and ceramic layers can be provided on the outside of the copper layers. The aerosol generator can be used to generate aerosols containing medicated materials.
摘要翻译：气溶胶发生器包括向流体通道供应流体的流体供应器和将流体加热成气态的加热器，流体通道位于层压体的相对的层之间。流体通道可以是通过将心轴定位在层压体的相对层之间而形成的毛细管尺寸通道，将层粘合在一起并移除心轴，使得先前被心轴占据的空间形成流体通道。层压体的相对层可以是铜片，并且可以在铜层的外侧设置陶瓷层。气溶胶发生器可用于产生含有药物的气溶胶。

7. 发明授权

US07373938B2 Disposable aerosol generator system and methods for administering the aerosol 有权
标题翻译：一次性气溶胶发生器系统和喷雾剂的施用方法
公开(公告)号：US07373938B2
公开(公告)日：2008-05-20
申请号：US10890233
申请日：2004-07-14
申请人： Walter A. Nichols , F. Murphy Sprinkel, Jr.
发明人： Walter A. Nichols , F. Murphy Sprinkel, Jr.
IPC分类号： A61M16/00 , F23D11/00
CPC分类号： A61M15/0045 , A61M11/002 , A61M11/041 , A61M11/042 , A61M15/0041 , A61M15/0048 , A61M2205/3653
摘要： A disposable aerosol generator for use with an inhaler device which includes a heater adapted to volatilize fluid stored in the disposable aerosol generator and method of using the inhaler. The disposable body includes a sealed chamber and an outlet, the chamber being located between first and second layers of material. The chamber holds a predetermined volume of a fluid which is expelled through the outlet when the fluid in the chamber is volatilized by the heater. The disposable body can include a series of spaced apart aerosol generators, each of which can be advanced to a release position at which the heater can heat one of the fluid containing chambers. Prior to heating the fluid, the outlet can be formed by severing the first and/or second layer with a piercing element and the volatilized fluid can be expelled from the outlet into a passage of a dispensing member.
摘要翻译：一种与吸入器装置一起使用的一次性气溶胶发生器，其包括适于使存储在一次性气雾发生器中的流体挥发的加热器和使用该吸入器的方法。一次性主体包括密封室和出口，该室位于第一和第二层材料之间。腔室容纳预定体积的流体，当腔室中的流体被加热器挥发时，流体通过出口排出。一次性本体可以包括一系列间隔开的气溶胶发生器，每个气溶胶发生器可以前进到释放位置，在该位置加热器可以加热流体容纳室中的一个。在加热流体之前，可以通过用穿孔元件切断第一和/或第二层而形成出口，并且挥发的流体可以从出口排出到分配构件的通道中。

8. 发明授权

US06823873B2 Cigarette having reduced sidestream smoke 有权
标题翻译：香烟具有减少的侧流烟雾
公开(公告)号：US06823873B2
公开(公告)日：2004-11-30
申请号：US10078536
申请日：2002-02-21
申请人： Walter A. Nichols , John R. Hearn , F. Murphy Sprinkel, Jr. , Jay A Fournier , Jerry F. Whidby
发明人： Walter A. Nichols , John R. Hearn , F. Murphy Sprinkel, Jr. , Jay A Fournier , Jerry F. Whidby
IPC分类号： D21H1100
CPC分类号： A24D1/02 , A24D1/00
摘要： A cigarette includes an ignition element in contact with tobacco, surrounded by a composite outer wrapper. The outer wrapper is impervious to oxygen causing the tobacco to extinguish between puffs. The ignition element, however, has a longer static burn time than the tobacco and remains smoldering between puffs. Upon a subsequent puff, the smoldering ignition element re-ignites the tobacco. One or more initially-occluded perforations in the outer layer maintain the uniformity in combustion of the tobacco and ignition element.
摘要翻译：香烟包括与烟草接触的点火元件，被复合外包装包围。外包装不透氧，导致烟草在泡芙之间熄灭。然而，点火元件具有比烟草更长的静态燃烧时间，并且在泡芙之间保持阴燃。在随后的抽吸中，闷燃的点火元件重新点燃烟草。外层中的一个或多个初始闭塞穿孔保持烟草和点燃元件的燃烧均匀性。

9. 发明授权

US07163014B2 Disposable inhaler system 有权
标题翻译：一次性吸入器系统
公开(公告)号：US07163014B2
公开(公告)日：2007-01-16
申请号：US10952434
申请日：2004-09-29
申请人： Walter A. Nichols , F. Murphy Sprinkel, Jr.
发明人： Walter A. Nichols , F. Murphy Sprinkel, Jr.
IPC分类号： A61M16/00 , A61M15/00
CPC分类号： A61M11/041 , A61M11/002 , A61M11/007 , A61M11/042 , A61M15/0041 , A61M15/0045 , A61M15/0048 , A61M2205/3653
摘要： A disposable aerosol generator for use with an inhaler device, which includes a heater adapted to volatilize liquid stored in the disposable aerosol generator and a method of using the inhaler, is provided. The disposable body includes a sealed chamber and an openable outlet. The chamber is located between first and second layers of material. The chamber holds liquid, which is expelled through the opened outlet when the fluid in the chamber is volatilized by the heater. The disposable body can include a series of spaced apart aerosol generators, each of which can be advanced to a release position at which the heater can heat one of the fluid containing chambers. Prior to heating the liquid, the outlet can be opened and the volatilized fluid can be expelled from the opened outlet into a passage of a dispensing member.
摘要翻译：一种与吸入器装置一起使用的一次性气溶胶发生器，其包括适于使存储在一次性气雾发生器中的液体挥发的加热器和使用该吸入器的方法。一次性本体包括密封室和可开启的出口。腔室位于第一和第二层材料之间。该室保持液体，当腔室中的流体被加热器挥发时，液体通过打开的出口排出。一次性本体可以包括一系列间隔开的气溶胶发生器，每个气溶胶发生器可以前进到释放位置，在该位置加热器可以加热流体容纳室中的一个。在加热液体之前，可以打开出口，并且挥发的流体可以从打开的出口排出到分配构件的通道中。

10. 发明授权

US06311694B1 Smoking article having reduced sidestream smoke 有权
标题翻译：具有减少侧流烟雾的吸烟制品
公开(公告)号：US06311694B1
公开(公告)日：2001-11-06
申请号：US09347027
申请日：1999-07-02
申请人： Walter A. Nichols , John R. Hearn , F. Murphy Sprinkel, Jr. , Jay A. Fournier , Jerry F. Whidby
发明人： Walter A. Nichols , John R. Hearn , F. Murphy Sprinkel, Jr. , Jay A. Fournier , Jerry F. Whidby
IPC分类号： A24F1302
CPC分类号： A24F13/00
摘要： A smoking article comprises a smoking accessory and a cigarette. The smoking accessory includes a holder and a substantially air-impermeable sleeve which is coupled to a distal portion of the holder and is coaxial therewith. The cigarette is received in the smoking accessory such that a distal end of the cigarette is located substantially flush with a distal end of the sleeve. The cigarette includes a column of tobacco which is shorter than that used in conventional cigarettes, e.g., 20 mm in length or less. An air gap separates an outer surface of the cigarette from the sleeve, and plural openings are formed in the sleeve to supply air to the cigarette. In use, the sleeve restricts the flow of air to the cigarette, thereby slowing combustion and reducing sidestream smoke between puffs.
摘要翻译：吸烟物品包括吸烟配件和香烟。吸烟配件包括保持器和基本上不透气的套筒，其联接到保持器的远侧部分并与其同轴。香烟被接收在吸烟配件中，使得香烟的远端基本上与套筒的远端齐平。香烟包括比常规香烟中使用的烟草短，例如长度为20毫米或更短的烟草柱。气隙将香烟的外表面与套筒分开，并且在套筒中形成多个开口以向香烟供应空气。在使用中，套筒限制空气流向香烟，从而减缓燃烧并减少泡芙之间的侧流烟雾。

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