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1. 发明申请

US20190231991A1 NEBULIZER ASSEMBLY AND AUXILIARY FLOW-GUIDING ELEMENT THEREOF 审中-公开
公开(公告)号：US20190231991A1
公开(公告)日：2019-08-01
申请号：US16199247
申请日：2018-11-26
申请人： HCMed Innovations Co., LTD.
发明人： Wen-Yu Tsai , Ke-Ting Chen , Chieh-Sheng Cheng
IPC分类号： A61M11/00 , A61M15/00
CPC分类号： A61M11/002 , A61M11/005 , A61M15/002 , A61M15/0021
摘要： A nebulizer assembly includes a nebulizer host and an auxiliary flow-guiding element. The auxiliary flow-guiding element is disposed on the nebulizer host. The auxiliary flow-guiding element has an auxiliary flow-guiding channel and at least one auxiliary bottom flow-guiding opening communicating with the auxiliary flow-guiding channel, and the auxiliary bottom flow-guiding opening penetrates through a bottom portion of the auxiliary flow-guiding element. A nebulized fluid generated by the nebulizer host can be sent to the auxiliary flow-guiding channel of the auxiliary flow-guiding element, and an outside air can pass through the auxiliary bottom flow-guiding opening and flow into the auxiliary flow-guiding channel. Therefore, the nebulized fluid in the auxiliary flow-guiding channel can be propelled towards a direction away from the auxiliary bottom flow-guiding opening by the outside air flowing into the auxiliary flow-guiding channel through the auxiliary bottom flow-guiding opening.

2. 发明申请

US20190192790A1 BREATH-ENHANCED JET NEBULIZER 审中-公开
公开(公告)号：US20190192790A1
公开(公告)日：2019-06-27
申请号：US16328939
申请日：2017-09-01
申请人： INSPIRX, INC. , THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
发明人： Rohinton D. TODDYWALA , Vijay SHUKLA , Gerald C. SMALDONE
IPC分类号： A61M11/00 , A61M15/00 , A61M11/06
CPC分类号： A61M11/002 , A61M11/003 , A61M11/06 , A61M15/0015 , A61M15/0016 , A61M15/0018 , A61M15/0021 , A61M2205/183 , A61M2205/44 , A61M2205/581 , A61M2206/14
摘要： A breath-enhanced jet nebulizer is configured with a low liquid retention reservoir and a narrow liquid delivery passage to efficiently and efficiently aerosolize small drug volumes with minimal waste. Aerosol particles are directed through aerosol passage for delivery, although larger liquid particles are directed away from the aerosol outlet and recycled to the liquid reservoir.

3. 发明申请

US20180311446A1 NEBULIZERS AND USES THEREOF 审中-公开
公开(公告)号：US20180311446A1
公开(公告)日：2018-11-01
申请号：US16026572
申请日：2018-07-03
申请人： OMEGA LIFE SCIENCE LTD.
发明人： Miron HAZANI
IPC分类号： A61M11/02 , A61M11/00 , A61M15/00
CPC分类号： A61M11/02 , A61M11/002 , A61M11/003 , A61M11/005 , A61M15/00 , A61M15/0001 , A61M15/0021 , A61M2202/0468 , A61M2205/0272 , A61M2205/0288 , A61M2205/103 , A61M2205/12 , A61M2205/123 , A61M2205/3331
摘要： The present disclosure generally relates to the field of nebulizers for aerosol generation and methods of using same for treating diseases and disorders.

4. 发明申请

US20180207374A1 Dose Delivery Device for Inhalation with First and Second Portions to Open a Dose Chamber 审中-公开
公开(公告)号：US20180207374A1
公开(公告)日：2018-07-26
申请号：US15924906
申请日：2018-03-19
申请人： Manta Devices, LLC
发明人： Andrew Jones , Richard L. Miller
IPC分类号： A61M15/00 , A61M11/00 , A61M16/04 , A61M11/02 , A61M11/06
CPC分类号： A61M11/002 , A61M11/008 , A61M11/02 , A61M11/06 , A61M15/0008 , A61M15/0013 , A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0035 , A61M15/004 , A61M15/0041 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/005 , A61M15/0061 , A61M15/0068 , A61M15/0075 , A61M15/0081 , A61M15/0086 , A61M15/0088 , A61M15/009 , A61M16/0495 , A61M2202/064 , A61M2205/071 , A61M2205/075 , A61M2205/6045 , A61M2205/6081 , A61M2205/8225 , A61M2206/16 , A61M2209/06
摘要： A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path.The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose.

5. 发明申请

US20180140785A1 DRY POWDER INHALER 审中-公开
公开(公告)号：US20180140785A1
公开(公告)日：2018-05-24
申请号：US15572495
申请日：2016-05-09
申请人： Iconovo AB
发明人： Orest LASTOW
IPC分类号： A61M15/00
CPC分类号： A61M15/0003 , A61M11/002 , A61M15/0065 , A61M2202/064 , A61M2206/14
摘要： A dry powder inhaler may include at least one air inlet, at least one air outlet, an air channel between said air inlet and outlet, and at least one medicament reservoir. The inhaler may include a dosage mechanism for arranging at least one dose of a medicament from said medicament reservoir between the air channel and the air outlet such that said at least one dose may be delivered upon inhalation at said air outlet. The dosage mechanism may include a dose disc with at least one cavity, wherein the dose disc may be rotatable between a dose collecting position, in which the cavity may be positioned in the medicament reservoir, and a dose administering position, in which the cavity may lie underneath the air channel. The inhaler may also include a floor disc abutting the dose disc underneath the cavity to form a bottom of the cavity for radial emptying of the medicament from the cavity during inhalation. Alternatively, the inhaler may include a floor disc abutting the dose disc underneath the cavity to form a bottom of the cavity and support the medicament in the cavity, wherein said dose disc may rotate in relation to the floor disc when the dose disc is rotated between the dose collecting position and the dose administering position to grind any residual medicament in the cavity.

6. 发明申请

US20180099107A1 TWO-STAGE APPARATUS AND METHOD FOR GENERATING AND CONCENTRATING FINE PARTICLE AEROSOLS 有权
公开(公告)号：US20180099107A1
公开(公告)日：2018-04-12
申请号：US15291028
申请日：2016-10-11
申请人： KAER BIOTHERAPEUTICS CORPORATION
发明人： Donovan B. Yeates , Xin Heng
IPC分类号： A61M11/02 , A61M16/12 , B05B7/04
CPC分类号： A61M11/02 , A61M11/002 , A61M11/006 , A61M11/06 , A61M15/0086 , A61M16/125 , A61M2202/0208 , A61M2202/0488 , A61M2202/064 , B05B7/0416 , A61M2202/0007
摘要： A system and a method for generating a respirable dry powder aerosol (15) from a liquid solution or liquid suspension at a respirable dry powder aerosol volume flow (91). A liquid aerosol generating nozzle (3) generates from the liquid solution or liquid suspension a liquid aerosol (13) that is diluted by dilution gas (4) and dried in a cylindrical evaporation chamber (6) to generate a dry powder aerosol (14) that is subsequently concentrated by a cylindrical single linear slit aerosol concentrator (9). The system and method may include heliox as a gas, specifically dilution gas (4), for enhancing both the drying process in the cylindrical evaporation chamber (6) and for enhancing the concentration efficiency, but also as a nozzle gas (2) for enhancing generating the liquid aerosol (13) from the liquid solution or liquid suspension.

7. 发明申请

US20170319795A1 DOSE DELIVERY DEVICE FOR INHALATION 审中-公开
公开(公告)号：US20170319795A1
公开(公告)日：2017-11-09
申请号：US15657888
申请日：2017-07-24
申请人： MANTA DEVICES, LLC
发明人： Andrew JONES , Richard L. MILLER
IPC分类号： A61M15/00 , A61M11/00 , A61M16/04 , A61M11/02 , A61M11/06
CPC分类号： A61M11/002 , A61M11/008 , A61M11/02 , A61M11/06 , A61M15/0008 , A61M15/0013 , A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0035 , A61M15/004 , A61M15/0041 , A61M15/0043 , A61M15/0045 , A61M15/0048 , A61M15/005 , A61M15/0061 , A61M15/0068 , A61M15/0075 , A61M15/0081 , A61M15/0086 , A61M15/0088 , A61M15/009 , A61M16/0495 , A61M2202/064 , A61M2205/071 , A61M2205/075 , A61M2205/6045 , A61M2205/6081 , A61M2205/8225 , A61M2206/16 , A61M2209/06
摘要： Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose.

8. 发明申请

US20170209655A1 DRY POWDER MEDICAMENT DE-AGGLOMERATOR 审中-公开
公开(公告)号：US20170209655A1
公开(公告)日：2017-07-27
申请号：US15325003
申请日：2015-07-21
申请人： MICRODOSE THERAPEUTX, INC.
发明人： Mark Steven Morrison
IPC分类号： A61M15/00
CPC分类号： A61M15/0008 , A61M11/002 , A61M11/02 , A61M15/0005 , A61M15/001 , A61M15/0028 , A61M15/0035 , A61M15/0045 , A61M2202/064 , A61M2205/07 , A61M2206/12 , A61M2206/14 , A61M2206/16
摘要： A de-agglomerator comprises: a medicament chamber comprising an inlet and outlet and having a cross-section with a substantially circular inner perimeter; a conduit in pneumatic communication with said inlet; and a blower arranged to direct airflow at dry powder medication through said conduit. Another de-agglomerator comprises: a piezoelectric transducer; a pumping chamber: coupled to said transducer through a diaphragm, and having a outlet hole: in a wall opposing the transducer, in line with the transducer axis, and arranged to be in pneumatic communication with a flow channel of said inhaler through which a user can inhale; and a housing surrounding said pumping chamber, comprising a housing inlet in a wall facing the transducer; a housing outlet in a wall facing said outlet hole and in line with the outlet hole; and being spaced from the pumping chamber by an airflow channel in pneumatic communication with the housing inlet and outlet.

9. 发明申请

US20170143915A1 AEROSOLISATION ENGINE FOR LIQUID DRUG DELIVERY BACKGROUND 审中-公开
公开(公告)号：US20170143915A1
公开(公告)日：2017-05-25
申请号：US15310346
申请日：2015-05-13
申请人： The Technology Partnership Plc
发明人： Daniel Geoffrey Tyler Strange , Robert Gordon Maurice Selby , Romain Ulysses Gabriel Guion , Timothy James Phillips , William Richardson
IPC分类号： A61M11/00 , A61F9/00 , B05B1/26 , A61M15/00 , A61M15/08
CPC分类号： A61M11/007 , A61F9/0008 , A61M11/002 , A61M11/003 , A61M15/0021 , A61M15/0065 , A61M15/08 , A61M2205/0238 , A61M2205/8225 , A61M2205/8281 , A61M2210/0612 , B05B1/262 , B05B14/00
摘要： A spray device for generating an aerosol of a liquid such as a medicament. The device includes a perforate element comprising one or more nozzles, each nozzle having an inlet and an outlet. A drive mechanism causes, in use, liquid to be driven through the one or more nozzles, thereby forming a liquid spray having one or more streams of liquid. At least one impaction surface is provided onto which, in use, the liquid impacts, the impaction surface being located downstream of the nozzle outlet(s).

10. 发明申请

US20170105246A1 Multiple Dose Condensation Aerosol Devices and Methods of Forming Condensation Aerosols 审中-公开
公开(公告)号：US20170105246A1
公开(公告)日：2017-04-13
申请号：US15388881
申请日：2016-12-22
申请人： Alexza Pharmaceuticals, Inc.
发明人： Steven D. Cross , Matthieu Herbette , Andrew J.G. Kelly , Daniel J. Myers , William W. Shen , Ryan D. Timmons , Curtis Tom , Justin M. Virgili , Martin J. Wensley
IPC分类号： H05B1/02 , A61M15/00 , A61M16/14 , A61M11/04
CPC分类号： H05B1/0244 , A61M11/002 , A61M11/041 , A61M11/042 , A61M15/0021 , A61M15/0045 , A61M15/0048 , A61M15/0065 , A61M15/008 , A61M15/0081 , A61M16/1075 , A61M16/14 , H05B2203/021
摘要： Devices and methods of entraining a substance within an airflow are disclosed. Condensation aerosol delivery devices and methods of consistently producing multiple doses of a substance, such as a drug, having high purity, high yield, characterized by a particle size distribution appropriate for pulmonary delivery, and which can be administered to a user in a single dose are also disclosed.

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