会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 3. 发明授权
    • High-density composite material
    • 高密度复合材料
    • US07304105B2
    • 2007-12-04
    • US10490493
    • 2002-09-30
    • Yasunao KaiMasahiro YamauchiKenji Okamura
    • Yasunao KaiMasahiro YamauchiKenji Okamura
    • C08K3/10
    • F42B12/745C08K3/013C08K3/08C08L9/06C08L23/00C08L21/00C08L2666/52
    • A composite material which comprises an elastomer or vulcanized rubber and particles of a high-density material, such as tungsten, evenly dispersed therein, wherein the contents of the elastomer or vulcanized rubber and the high-density particles are 35 to 50 vol. % and 50 to 65 vol. %, respectively, based on the whole composite material, and the high-density particles have a particle composition comprising 60 to 80 vol. % coarse particles having a particle diameter of 10 to 100 μm, 10 to 20 vol. % medium particles having a particle diameter of 3 to 6 μm, and 10 to 20 vol. % fine particles having a particle diameter of 1 to 2 μm, the spaces among the coarse particles being filled with the medium particles and fine particles. The composite material is excellent in flexibility and processability and is suitable for use as a radiation-shielding sheet material, weight member, vibration-damping material, balancing member, radiating material, and shot material.
    • 包含弹性体或硫化橡胶的复合材料以及均匀分散在其中的诸如钨的高密度材料的颗粒,其中弹性体或硫化橡胶和高密度颗粒的含量为35〜50体积%。 %和50至65体积% %,基于整个复合材料,高密度颗粒具有60至80体积%的颗粒组成。 粒径为10〜100μm的粗粒子,10〜20体积% 粒径为3〜6μm的中等粒径的微粒,10〜20体积% 粒径为1〜2μm的微细粒子,粗粒子之间的空隙填充有中等粒子和微粒。 复合材料的柔软性和加工性优异,适用于辐射屏蔽片材,重量件,减振材料,平衡构件,辐射材料和射出材料。
    • 4. 发明申请
    • High-density composite material
    • 高密度复合材料
    • US20050004290A1
    • 2005-01-06
    • US10490493
    • 2002-09-30
    • Yasunao KaiMasahiro YamauchiKenji Okamura
    • Yasunao KaiMasahiro YamauchiKenji Okamura
    • C08K3/00C08K3/08F42B12/74C08L1/00
    • F42B12/745C08K3/013C08K3/08C08L9/06C08L23/00C08L21/00C08L2666/52
    • A composite material which comprises an elastomer or vulcanized rubber and particles of a high-density material, such as tungsten, evenly dispersed therein, wherein the contents of the elastomer or vulcanized rubber and the high-density particles are 35 to 50 vol. % and 50 to 65 vol. %, respectively, based on the whole composite material, and the high-density particles have a particle composition comprising 60 to 80 vol. % coarse particles having a particle diameter of 10 to 100 μm, 10 to 20 vol. % medium particles having a particle diameter of 3 to 6 μm, and 10 to 20 vol. % fine particles having a particle diameter of 1 to 2 μm, the spaces among the coarse particles being filled with the medium particles and fine particles. The composite material is excellent in flexibility and processability and is suitable for use as a radiation-shielding sheet material, weight member, vibration-damping material, balancing member, radiating material, and shot material.
    • 包含弹性体或硫化橡胶的复合材料以及均匀分散在其中的诸如钨的高密度材料的颗粒,其中弹性体或硫化橡胶和高密度颗粒的含量为35〜50体积%。 %和50至65体积% %,基于整个复合材料,高密度颗粒具有60至80体积%的颗粒组成。 粒径为10〜100μm的粗粒子,10〜20体积% 粒径为3〜6μm的中等粒径的微粒,10〜20体积% 粒径为1〜2μm的微细粒子,粗粒子之间的空隙填充有中等粒子和微粒。 复合材料的柔软性和加工性优异,适合用作辐射屏蔽片材,重量件,减震材料,平衡构件,辐射材料和射出材料。
    • 8. 发明申请
    • METHOD OF INHIBITING LEAKAGE OF DRUG ENCAPSULATED IN LIPOSOMES
    • 抑制在脂质体中浸润的药物的渗漏方法
    • US20090041835A1
    • 2009-02-12
    • US12139702
    • 2008-06-16
    • Yusuki KatoMasahiro YamauchiHiroko KusanoAtsushi Ishihara
    • Yusuki KatoMasahiro YamauchiHiroko KusanoAtsushi Ishihara
    • A61K9/127A61K31/407
    • A61K31/55A61K9/127
    • The present invention provides a method of inhibiting the leakage of a drug encapsulated in liposomes, which comprises satisfying at least two requirements selected from the group consisting of the following three requirements: using at least two lipid bilayers of the liposomes, controlling the average particle size of the liposomes to 120 nm or more, and using lipid having a phase transition temperature higher than in vivo temperature as lipid constituting the liposomes. Also, the present invention provides a liposome preparation which is stable in vivo and satisfies at least two requirements selected from the group consisting of the following three requirements: the number of lipid bilayers of the liposomes is at least two, the liposomes have an average particle size of 120 nm or more, and lipid constituting the liposomes has a phase transition temperature higher than in vivo temperature.
    • 本发明提供一种抑制包封在脂质体中的药物的泄漏的方法,其包括满足选自以下三个要求的至少两个要求:使用脂质体的至少两个脂质双层,控制平均粒径 的脂质体达到120nm以上,并且使用具有比体内温度高的相变温度的脂质作为构成脂质体的脂质。 另外,本发明提供脂质体制剂,其在体内稳定且满足选自以下三个要求的至少两个要求:脂质体的脂质双层数至少为2个,脂质体具有平均粒子 大小为120nm以上,构成脂质体的脂质的相转变温度高于体内温度。
    • 9. 发明申请
    • Complex Particles and Coated Complex Particles
    • 复合颗粒和涂层复合颗粒
    • US20090010999A1
    • 2009-01-08
    • US10591827
    • 2005-03-10
    • Masahiro YamauchiYasuki Kato
    • Masahiro YamauchiYasuki Kato
    • A61K9/127A61K9/14A61K31/711A61K31/7105A61K31/7088
    • A61K9/1272A61K9/1271A61K31/7088A61K31/713
    • The present invention provides, for example, a method of inhibiting aggregation of complex particles in which a drug is adhered to lead particles, characterized by containing a lipid derivative or a fatty acid derivative of one or more substance(s) selected from sugars, peptides, nucleic acids and water-soluble polymers or a surfactant in the lead particles. Further, it provides, for example, a method of producing the complex particles in which a nucleic acid as a drug or a drug is adhered to lead particles, comprising the step of dispersing or dissolving the nucleic acid as a drug or the drug and an adhesion-competitive agent so as to be contained in a liquid in which the lead particles containing a lipid derivative or a fatty acid derivative of one or more substance(s) selected from sugars, peptides, nucleic acids and water-soluble polymers or a surfactant are dispersed, thereby allowing the nucleic acid as a drug or the drug and the adhesion-competitive agent adhered to the lead particles.
    • 本发明提供了例如抑制药物粘附于铅粒子的复合粒子聚集的方法,其特征在于,含有选自糖,肽的一种或多种物质的脂质衍生物或脂肪酸衍生物 ,核酸和水溶性聚合物或铅颗粒中的表面活性剂。 此外,例如提供了将作为药物或药物的核酸与铅粒子附着的复合粒子的制造方法,其包括将核酸作为药物或药物分散或溶解的工序,以及 粘附竞争剂,以便包含在其中含有选自糖,肽,核酸和水溶性聚合物的一种或多种物质的脂质衍生物或脂肪酸衍生物的铅颗粒的液体中,或表面活性剂 从而允许作为药物或药物的核酸和附着于铅颗粒的粘附竞争性试剂。