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1. 发明授权

US5294550A Method of culturing Mishima-saiko 失效
标题翻译：三岛子的培养方法
公开(公告)号：US5294550A
公开(公告)日：1994-03-15
申请号：US913884
申请日：1992-07-17
申请人： Ken Kusakari , Mineyuki Yokoyama , Mitsuo Yanagi
发明人： Ken Kusakari , Mineyuki Yokoyama , Mitsuo Yanagi
IPC分类号： A01H4/00 , A01H5/02 , C12N5/04 , C12P19/44 , C12N5/00 , C12N5/02
CPC分类号： A01H4/00 , A01H5/02 , C12N5/04
摘要： An improved process for the organ cultivation of a Mishima-saiko root is provided. In the cultivation of a Mishima-saiko root, by carrying out the cultivation while regulating the saccharide concentration to be less than 2%, until the adventitious roots have spread out, and optionally adding an additional saccharide, the productivity of saiko-saponin can be enhanced.
摘要翻译：提供了改良三岛根的器官培养方法。在三岛根的培养中，通过在调节糖浓度小于2％的同时进行培养，直到不定根扩散，并且任选地加入另外的糖，可以将saiko-saponin的生产率增强。

2. 发明申请

US20130029391A1 METHOD OF PREPARING KODA USING LEMNA PAUCICOSTATA 审中-公开
标题翻译：使用LEMNA PAUCICOSTATA制备柯达的方法
公开(公告)号：US20130029391A1
公开(公告)日：2013-01-31
申请号：US13583975
申请日：2011-03-11
申请人： Mineyuki Yokoyama , Toshio Beppu
发明人： Mineyuki Yokoyama , Toshio Beppu
IPC分类号： C12P7/42
CPC分类号： C07C59/76 , C12N9/0069 , C12N9/88 , C12N15/8247 , C12P7/42
摘要： After identifying the genes of a novel lipoxygenase and a novel allene oxide synthase derived from Lemna paucicostata SH strain, a plant growth regulating agent (KODA) was produced at high yield by using a Lemna paucicostata strain that expresses the lipoxygenase and the allene oxide synthase.
摘要翻译：鉴定出一种新型脂氧合酶基因和一种源自Lemna paucicostata SH菌株的新型烯氧化物合酶，通过使用表达脂氧合酶和氧化烯合酶的Lemna paucicostata菌株，以高产量生产植物生长调节剂（KODA）。

3. 发明授权

US07749508B2 Skin whitening method using Pleurotus nebrodensis 失效
标题翻译：使用侧耳菇的皮肤美白方法
公开(公告)号：US07749508B2
公开(公告)日：2010-07-06
申请号：US12365985
申请日：2009-02-05
申请人： Takeshi Nawamura , Nobuhiko Ochiai , Masato Hatao , Mineyuki Yokoyama , Koji Kobayashi , Fumio Eguchi
发明人： Takeshi Nawamura , Nobuhiko Ochiai , Masato Hatao , Mineyuki Yokoyama , Koji Kobayashi , Fumio Eguchi
IPC分类号： A61K35/84
CPC分类号： A61K36/07 , A61K8/9706 , A61K2800/522 , A61K2800/782 , A61Q19/02 , A61Q19/08
摘要： The present invention provides an antioxidant and a whitening agent having high safety, and a external preparation for skin using the same. The antioxidant and whitening agent comprise, as an effective component, one or more extracts from Basidiomycetes selected from the group consisting of Pleurotus abalonus, Pholiota squarrosa, Onnia orientalis, Astraeus hygrometricus and Pleurotus nebrodensis . These extracts have a free radical capturing ability and are useful for suppressing skin oxidation and for preventing and improving skin aging. In addition, the extracts have a tyrosinase activity inhibiting action and can suppress the melanin generation. Since the fruit bodies of these Basidiomycetes have been used for edible purpose and have high safety, they can be used preferably for an external preparation for skin.
摘要翻译：本发明提供了具有高安全性的抗氧化剂和增白剂，以及使用其的皮肤外用剂。抗氧化剂和增白剂作为有效成分包含一种或多种从担子菌中提取的提取物，所述提取物选自侧耳属（Pleurotus abalonus），Pholiota squarrosa，Onnia orientalis，Astraeus hygrometricus和Pleurotus nebrodensis。这些提取物具有自由基捕获能力，可用于抑制皮肤氧化和预防和改善皮肤老化。此外，提取物具有酪氨酸酶活性抑制作用，能够抑制黑色素的产生。由于这些担子菌的果实体已被用于食用，安全性高，所以可以优选用于皮肤外用剂。

4. 发明申请

US20080234133A1 Plant activator 审中-公开
标题翻译：植物激活剂
公开(公告)号：US20080234133A1
公开(公告)日：2008-09-25
申请号：US12011322
申请日：2008-01-25
申请人： Mineyuki Yokoyama , Shoko Yamaguchi , Toshii Iida , Kiyotaka Kojima , Koji Kobayashi , Osamu Tanaka
发明人： Mineyuki Yokoyama , Shoko Yamaguchi , Toshii Iida , Kiyotaka Kojima , Koji Kobayashi , Osamu Tanaka
IPC分类号： A01N37/06 , A01P21/00
CPC分类号： A01N37/42
摘要： An object of the present invention is to determine novel means of activating plants; more particularly, means of controlling plant growth, such as means of promoting growth, means of controlling dormancy, means of imparting tolerance against stress for plants (dryness, high or low temperatures, osmotic pressure, etc.), and means of preventing aging. The present inventors have found that the above object can be achieved by providing plant activators containing, as an active ingredient, C4-C24 ketol fatty acids, in particular, 9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid.
摘要翻译：本发明的目的是确定活化植物的新方法; 更具体地，是控制植物生长的手段，例如促进生长的手段，控制休眠的手段，赋予植物胁迫耐受性的手段（干燥，高温或低温，渗透压等）以及防止老化的手段。本发明人已经发现，上述目的可以通过提供含有作为有效成分的C 4 -C 24脂肪醇脂肪酸的植物活化剂来实现，特别是9 - 羟基-10-氧代-12（Z），15（Z） - 十八碳二烯酸。

5. 发明授权

US06338861B1 Process of production of natural flavor or fragrance 失效
标题翻译：生产天然香精或香料的过程
公开(公告)号：US06338861B1
公开(公告)日：2002-01-15
申请号：US09276737
申请日：1999-03-26
申请人： Yoko Gozu , Mineyuki Yokoyama , Shoko Yamaguchi , Katsuyuki Yomogida , Shinichiro Haze
发明人： Yoko Gozu , Mineyuki Yokoyama , Shoko Yamaguchi , Katsuyuki Yomogida , Shinichiro Haze
IPC分类号： A61K3578
CPC分类号： A23L27/24
摘要： A natural flavor or fragrance can be easily and effectively produced by using a “unicellularized plant”, obtained by unicellularizing, without destroying, the cells of a plant usable as a starting material for a natural flavor or fragrance, as a material for the natural flavor or fragrance and further applying an enzymatic treatment or chemical treatment or continuously heating the same, to thereby remarkably shorten the aging period for producing the natural flavor or fragrance, or by homogenizing a plant usable as the starting material quickly after harvesting to thereby promote the aging.
摘要翻译：通过使用通过单细胞化获得的“单细胞化植物”，而不破坏可用作天然风味或香料的起始材料的植物的细胞作为天然风味的材料，可以容易且有效地产生天然风味或香味或香料，进一步进行酶处理或化学处理或连续加热，从而显着缩短生产天然香料或香料的老化时间，或者通过在收获后快速均匀化作为原料的植物，从而促进老化。

6. 发明申请

US20130224829A1 NOVEL LIPOXYGENASE DERIVED FROM LEMNA PAUCICOSTATA 审中-公开
标题翻译：从LEMNA PAUCICOSTATA衍生的新的LIPOXYGENASE
公开(公告)号：US20130224829A1
公开(公告)日：2013-08-29
申请号：US13583950
申请日：2011-03-11
申请人： Mineyuki Yokoyama , Kazuteru Takagi , Sari Kamichi
发明人： Mineyuki Yokoyama , Kazuteru Takagi , Sari Kamichi
IPC分类号： C12N9/02 , C12N5/10 , C12N1/00 , C12N15/53 , C12N15/63
CPC分类号： C12N9/0069
摘要： A highly active novely lypoxygenase cDNA derived from Lemna paucicostata SH strain and Lemna paucicostata 441 strain and a protein encoded by the cDNA are provided.
摘要翻译：提供了从Lemna paucicostata SH菌株和Lemna paucicostata 441菌株得到的高活性的novely lypoxygenase cDNA和由cDNA编码的蛋白质。

7. 发明授权

US08519173B2 Plant growth regulator 失效
标题翻译：植物生长调节剂
公开(公告)号：US08519173B2
公开(公告)日：2013-08-27
申请号：US13395948
申请日：2010-09-13
申请人： Mineyuki Yokoyama
发明人： Mineyuki Yokoyama
IPC分类号： C07C59/00 , A01N25/00
CPC分类号： C07C59/90 , A01N37/42 , A01N53/00 , C07C2601/02
摘要： Provided is a plant growth regulator having for an active ingredient thereof an α-ketol fatty acid derivative represented by the following general formula (1)
摘要翻译：本发明提供一种具有活性成分的植物生长调节剂，其由以下通式（1）表示的α-酮醇脂肪酸衍生物，

8. 发明申请

US20090208525A1 Antiaging method for skin using pleurotus abalonus 审中-公开
标题翻译：使用Pleurotus abalonus的皮肤抗衰老方法
公开(公告)号：US20090208525A1
公开(公告)日：2009-08-20
申请号：US12367591
申请日：2009-02-09
申请人： Takeshi Nawamura , Nobuhiko Ochiai , Masato Hatao , Mineyuki Yokoyama , Koji Kobayashi , Fumio Eguchi
发明人： Takeshi Nawamura , Nobuhiko Ochiai , Masato Hatao , Mineyuki Yokoyama , Koji Kobayashi , Fumio Eguchi
IPC分类号： A61K36/07 , A61Q19/08
CPC分类号： A61K36/07 , A61K8/9706 , A61K2800/522 , A61K2800/782 , A61Q19/02 , A61Q19/08
摘要： The present invention provides an antioxidant and a whitening agent having high safety, and a external preparation for skin using the same. The antioxidant and whitening agent comprise, as an effective component, one or more extracts from Basidiomycetes selected from the group consisting of Pleurotus abalonus, Pholiota squarrosa, Onnia orientalis, Astraeus hygrometricus and Pleurotus nebrodensis. These extracts have a free radical capturing ability and are useful for suppressing skin oxidation and for preventing and improving skin aging. In addition, the extracts have a tyrosinase activity inhibiting action and can suppress the melanin generation. Since the fruit bodies of these Basidiomycetes have been used for edible purpose and have high safety, they can be used preferably for an external preparation for skin.
摘要翻译：本发明提供了具有高安全性的抗氧化剂和增白剂，以及使用其的皮肤外用剂。抗氧化剂和增白剂作为有效成分包含一种或多种从担子菌中提取的提取物，所述提取物选自侧耳属（Pleurotus abalonus），Pholiota squarrosa，Onnia orientalis，Astraeus hygrometricus和Pleurotus nebrodensis。这些提取物具有自由基捕获能力，可用于抑制皮肤氧化和预防和改善皮肤老化。此外，提取物具有酪氨酸酶活性抑制作用，能够抑制黑色素的产生。由于这些担子菌的果实体已被用于食用，安全性高，所以可以优选用于皮肤外用剂。

9. 发明申请

US20070293400A1 Inducing Agent for Plant Root 审中-公开
标题翻译：植物根系诱导剂
公开(公告)号：US20070293400A1
公开(公告)日：2007-12-20
申请号：US11587383
申请日：2005-04-27
申请人： Mineyuki Yokoyama , Osamu Tanaka , Kentaro Nakamura
发明人： Mineyuki Yokoyama , Osamu Tanaka , Kentaro Nakamura
IPC分类号： A01N37/06 , A01P21/00
CPC分类号： A01N37/42 , A01N2300/00 , A01N25/00 , A01N43/38
摘要： An inducing agent for plant root including a ketol unsaturated fatty acid having 5 to 24 carbon atoms, 1 to 6 double bonds between carbon atoms and an α ketol structure or γ ketol structure (in particular 9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid is preferable), which inducing agent for plant root may be used to promote or induce the root growth even when transplanting by cutting plants for which root generation is hard such as pine, cedar, tea, chestnut, may be used even for root growth of cuttings of Prunus×yedoensis (cherry trees) for which root growth is considered impossible, Hypericum chinense for which is transplantation by cutting is said to be difficult, and Paraserianthes falcataria Becker useful as a material for plywood, and may be used by a simple technique such as spraying.
摘要翻译：一种植物根系诱导剂，包括具有5至24个碳原子的酮醇不饱和脂肪酸，1至6个碳原子之间的双键和α酮醇结构或γ酮醇结构（特别是9-羟基-10-氧代-12（Z ），15（Z） - 十八碳二烯酸是优选的），即使通过切割具有硬根的植物，例如松木，雪松，茶叶，栗子等植物，也可以将植物根的诱导剂用于促进或诱导根生长，甚至可以用于根长生根被认为是不可能的黄瓜（樱桃树）的根的生长，其中通过切割移植的金丝桃味被认为是困难的，并且Paraseranthes falcataria Becker可用作胶合板的材料，以及可以通过诸如喷雾的简单技术来使用。

10. 发明授权

US06419962B1 External skin treatment composition 失效
标题翻译：外用皮肤护理组合物
公开(公告)号：US06419962B1
公开(公告)日：2002-07-16
申请号：US08883044
申请日：1997-06-26
申请人： Mineyuki Yokoyama , Hiroyuki Tsukada , Tetsuya Sakai , Shoko Yamaguchi , Yumiko Suzuki , Yasukazu Nakayama , Hiroaki Yasuhara , Okihiko Sakamoto
发明人： Mineyuki Yokoyama , Hiroyuki Tsukada , Tetsuya Sakai , Shoko Yamaguchi , Yumiko Suzuki , Yasukazu Nakayama , Hiroaki Yasuhara , Okihiko Sakamoto
IPC分类号： A61K3578
CPC分类号： A61Q19/00 , A61K8/0212 , A61K8/06 , A61K8/97 , A61Q1/02 , A61Q1/06 , A61Q1/08 , A61Q1/10 , A61Q1/12 , A61Q5/02 , A61Q5/065 , A61Q19/002 , A61Q19/10
摘要： An external skin treatment composition is described that comprises a “unicellularized” plant. This composition exhibits superior stability of the effective plant ingredients, superior moisture retention, and superior elimination of specific free radicals, and it offers sustained release of the effective plant ingredients. Methods are disclosed to unicellularize plants with, for example, an enzyme.
摘要翻译：描述了包含“单细胞化”植物的外部皮肤处理组合物。该组合物表现出优异的有效植物成分的稳定性，优异的保湿性和优异的特定自由基的消除，并提供有效植物成分的持续释放。公开了用例如酶将植物单细胞化的方法。

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