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1. 发明授权

US07218091B1 Integrated CMOS spectrum analyzer for on-chip diagnostics using digital autocorrelation of coarsely quantized signals 有权
标题翻译：集成CMOS频谱分析仪，用于使用数字自相关粗量化信号进行片上诊断
公开(公告)号：US07218091B1
公开(公告)日：2007-05-15
申请号：US11485390
申请日：2006-07-13
申请人： Keith A. Jenkins , Stanislav Polonsky
发明人： Keith A. Jenkins , Stanislav Polonsky
IPC分类号： G01R23/00
CPC分类号： G01R23/16
摘要： An integrated spectrum analyzer for performing on-chip power spectrum measurements, includes a digital autocorrelator that includes an analog input for inputting analog signal samples from a chip, an analog-to-digital converter for converting the analog signal samples into digital signal samples, a storage register for storing a first converted digital signal sample for a period of time, a digital multiplier for multiplying the first stored digital signal after the period of time with a second undelayed digital signal sample to produce a product of multiplication, and an accumulator for accumulating a plurality of products of multiplication for each new period of time. The digital autocorrelator computes an autocorrelation function based on the analog signal samples and is integrally formed on the chip for performing power spectrum measurements on the analog signal samples to compute the autocorrelation function.
摘要翻译：一种用于进行片上功率谱测量的集成频谱分析仪，包括数字自相关器，其包括用于输入来自芯片的模拟信号样本的模拟输入，用于将模拟信号样本转换成数字信号样本的模数转换器，存储寄存器，用于存储一段时间内的第一转换数字信号采样;数字乘法器，用于将所述时间段之后的第一存储数字信号与第二未延迟数字信号采样相乘以产生乘法乘积;以及累加器，用于累加多个产品的乘法每个新的时间段。数字自相关器基于模拟信号样本计算自相关函数，并且一体形成在芯片上，用于对模拟信号采样进行功率谱测量，以计算自相关函数。

2. 发明授权

US09453831B2 Nanopore capture system 有权
公开(公告)号：US09453831B2
公开(公告)日：2016-09-27
申请号：US13452857
申请日：2012-04-21
申请人： Stanislav Polonsky , Ali Afzali-Ardakani , Hongbo Peng , Gustavo A. Stolovitzky , Ajay A. Royyuru , Mark N. Wegman
发明人： Stanislav Polonsky , Ali Afzali-Ardakani , Hongbo Peng , Gustavo A. Stolovitzky , Ajay A. Royyuru , Mark N. Wegman
IPC分类号： G01N33/487 , G01N33/543
CPC分类号： G01N33/48721 , G01N33/54373
摘要： A nanopore capture system may include a material configured to pass through a nanopore device in a controlled manner based upon its interaction with the nanopore device. The system may also include a capture mechanism connected to one end of the material. The capture mechanism may be configured to catch a particular type of molecule while ignoring other types of molecules. The system may also include a controller to manipulate and/or detect the particular type of molecule.

3. 发明授权

US08641879B2 Charged entities as locomotive to control motion of polymers through a nanochannel 有权
公开(公告)号：US08641879B2
公开(公告)日：2014-02-04
申请号：US13611662
申请日：2012-09-12
申请人： Stefan Harrer , Binquan Luan , Glenn J. Martyna , Hongbo Peng , Stanislav Polonsky , Stephen M. Rossnagel , Ajay K. Royyuru , Gustavo A. Stolovitzky , George F. Walker
发明人： Stefan Harrer , Binquan Luan , Glenn J. Martyna , Hongbo Peng , Stanislav Polonsky , Stephen M. Rossnagel , Ajay K. Royyuru , Gustavo A. Stolovitzky , George F. Walker
IPC分类号： G01N27/26
CPC分类号： B82Y15/00 , C12Q1/6869 , C12Q2565/631
摘要： A technique for controlling the motion of one or more charged entities linked to a polymer through a nanochannel is provided. A first reservoir and a second reservoir are connected by the nanochannel. An array of electrodes is positioned along the nanochannel, where fluid fills the first reservoir, the second reservoir, and the nanochannel. A first electrode is in the first reservoir and a second electrode is in the second reservoir. The first and second electrodes are configured to direct the one or more charged entities linked to the polymer into the nanochannel. An array of electrodes is configured to trap the one or more charged entities in the nanochannel responsive to being controlled for trapping. The array of electrodes is configured to move the one or more charged entities along the nanochannel responsive to being controlled for moving.

4. 发明授权

US08598018B2 Forming an electrode having reduced corrosion and water decomposition on surface using a custom oxide layer 失效
标题翻译：使用定制的氧化物层形成表面上具有降低的腐蚀和水分解的电极
公开(公告)号：US08598018B2
公开(公告)日：2013-12-03
申请号：US12820487
申请日：2010-06-22
申请人： Ali Afzali-Azdakani , Shafaat Ahmed , Hariklia Deligianni , Dario L. Goldfarb , Stefan Harrer , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Xiaoyan Shao , Gustavo A. Stolovitzky
发明人： Ali Afzali-Azdakani , Shafaat Ahmed , Hariklia Deligianni , Dario L. Goldfarb , Stefan Harrer , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Xiaoyan Shao , Gustavo A. Stolovitzky
IPC分类号： H01L21/20 , H01L21/36 , H01L21/283
CPC分类号： C23C8/02 , C23C8/36 , C23C14/5853 , G01N33/48721
摘要： The present invention provides a method of forming an electrode having reduced corrosion and water decomposition on a surface thereof. A conductive layer is deposited on a substrate. The conductive layer is partially oxidized by an oxygen plasma process to convert a portion thereof to an oxide layer thereby forming the electrode. The oxide layer is free of surface defects and the thickness of the oxide layer is from about 0.09 nm to about 10 nm and ranges therebetween, controllable with 0.2 nm precision.
摘要翻译：本发明提供一种在其表面上形成具有降低的腐蚀和水分解的电极的方法。导电层沉积在基底上。导电层被氧等离子体工艺部分地氧化，将其一部分转化成氧化层，从而形成电极。氧化物层没有表面缺陷，氧化物层的厚度为约0.09nm至约10nm，并且其间的范围可以0.2nm精度控制。

5. 发明授权

US08189931B2 Method and apparatus for matching of bracketed patterns in test strings 失效
标题翻译：用于匹配测试串中的括号图案的方法和装置
公开(公告)号：US08189931B2
公开(公告)日：2012-05-29
申请号：US11969451
申请日：2008-01-04
申请人： Tien Huynh , Stanislav Polonsky , Isidore Rigoutsos
发明人： Tien Huynh , Stanislav Polonsky , Isidore Rigoutsos
IPC分类号： G06K9/00 , G06F17/30
CPC分类号： G06F17/30985
摘要： A method and system are disclosed for matching input character sequences in a set of input patterns. The method comprises the steps of analyzing the set of input patterns, creating a pattern cluster look-up table (PCLT) based on said input patterns, and defining an offset value k. The PCLT is used to find, for each sequence s and offset k, a set of candidate patterns that can possibly match s, the set of candidate patterns is searched for patterns that match s, and all found matching patterns and sequences are reported.
摘要翻译：公开了一种用于在一组输入模式中匹配输入字符序列的方法和系统。该方法包括以下步骤：分析输入模式集，基于所述输入模式创建模式集群查找表（PCLT），并定义偏移值k。 PCLT用于针对每个序列s和偏移k找到一组可能匹配s的候选模式，搜索匹配s的模式的候选模式集合，并且报告所有找到的匹配模式和序列。

6. 发明申请

US20120065765A1 DETECTING DOSE AND FOCUS VARIATIONS DURING PHOTOLITHOGRAPHY 失效
标题翻译：在光刻技术中检测剂量和焦点变化
公开(公告)号：US20120065765A1
公开(公告)日：2012-03-15
申请号：US12881548
申请日：2010-09-14
申请人： IBRAHIM M. ELFADEL , Ying Liu , Stanislav Polonsky , Amith Singhee
发明人： IBRAHIM M. ELFADEL , Ying Liu , Stanislav Polonsky , Amith Singhee
IPC分类号： G06F19/00
CPC分类号： G03F7/705 , G03F7/70658
摘要： A method, system, and computer usable program product for detecting dose and focus variations during photolithography are provided in the illustrative embodiments. A test shape is formed on a wafer, the wafer being used to manufacture integrated circuits, the test shape being formed using a dose value and a focus value that are predetermined for the manufacturing. A capacitance of the test shape is measured. The capacitance is resolved to a second dosing value and a second focus value using an extraction model. A difference between the dosing value and the second dosing value is computed. A recommendation is made for dosing adjustment in the manufacturing based on the difference.
摘要翻译：在说明性实施例中提供了用于在光刻期间检测剂量和聚焦变化的方法，系统和计算机可用程序产品。在晶片上形成测试形状，该晶片用于制造集成电路，该测试形状使用为制造预定的剂量值和聚焦值形成。测量测试形状的电容。使用提取模型将电容解析为第二计量值和第二焦点值。计算给药值和第二给药值之间的差异。基于差异，建议制造中的剂量调整。

7. 发明申请

US20110312164A1 FORMING AN ELECTRODE HAVING REDUCED CORROSION AND WATER DECOMPOSITION ON SURFACE USING A CUSTOM OXIDE LAYER 失效
标题翻译：使用自定义氧化层形成具有降低腐蚀性和表面水分解的电极
公开(公告)号：US20110312164A1
公开(公告)日：2011-12-22
申请号：US12820487
申请日：2010-06-22
申请人： Ali Afzali-Azdakani , Shafaat Ahmed , Hariklia Deligianni , Dario L. Goldfarb , Stefan Harrer , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Xiaoyan Shao , Gustavo A. Stolovitzky
发明人： Ali Afzali-Azdakani , Shafaat Ahmed , Hariklia Deligianni , Dario L. Goldfarb , Stefan Harrer , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Xiaoyan Shao , Gustavo A. Stolovitzky
IPC分类号： H01L21/20 , H01L21/36 , C23C14/34 , G03F7/20 , C30B23/02 , C30B25/02 , C23C28/00 , B05D3/06 , C23C14/08
CPC分类号： C23C8/02 , C23C8/36 , C23C14/5853 , G01N33/48721
摘要： The present invention provides a method of forming an electrode having reduced corrosion and water decomposition on a surface thereof. A conductive layer is deposited on a substrate. The conductive layer is partially oxidized by an oxygen plasma process to convert a portion thereof to an oxide layer thereby forming the electrode. The oxide layer is free of surface defects and the thickness of the oxide layer is from about 0.09 nm to about 10 nm and ranges therebetween, controllable with 0.2 nm precision.
摘要翻译：本发明提供一种在其表面上形成具有降低的腐蚀和水分解的电极的方法。导电层沉积在基底上。导电层被氧等离子体工艺部分地氧化，将其一部分转化成氧化层，从而形成电极。氧化物层没有表面缺陷，氧化物层的厚度为约0.09nm至约10nm，并且其间的范围可以0.2nm精度控制。

8. 发明申请

US20110308949A1 NANO-FLUIDIC FIELD EFFECTIVE DEVICE TO CONTROL DNA TRANSPORT THROUGH THE SAME 有权
标题翻译：用于控制DNA运输的纳米流体场效应装置
公开(公告)号：US20110308949A1
公开(公告)日：2011-12-22
申请号：US12820516
申请日：2010-06-22
申请人： Ali Afzali-Azdakani , Stefan Harrer , Binquan Luan , Glenn J. Martyna , Dennis M. Newns , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Gustavo Stolovitzky
发明人： Ali Afzali-Azdakani , Stefan Harrer , Binquan Luan , Glenn J. Martyna , Dennis M. Newns , Hongbo Peng , Stanislav Polonsky , Stephen Rossnagel , Gustavo Stolovitzky
IPC分类号： G01N27/447 , C25B11/00
CPC分类号： G01N27/44756 , B01L3/502761 , B01L2200/0663 , B01L2300/0645 , B01L2300/0816 , B01L2300/0896 , B01L2400/0421 , B01L2400/0424 , B82Y15/00 , G01N27/447 , G01N27/44791 , G01N33/48721
摘要： The present invention provides a nano-fluidic field effective device. The device includes a channel having a first side and a second side, a first set of electrodes adjacent to the first side, a second set of electrodes adjacent to the second side, a control unit for applying electric potentials to the electrodes and a fluid within the channel containing a charge molecule. The first set of electrodes is disposed such that application of electric potentials produces a spatially varying electric field that confines a charged molecule within a predetermined area of said channel. The second set of electrodes is disposed such that application of electric potentials relative to the electric potentials applied to the first set of electrodes creates an electric field that confines the charged molecule to an area away from the second side of the channel.
摘要翻译：本发明提供一种纳米流体场有效装置。该装置包括具有第一侧和第二侧的通道，与第一侧相邻的第一组电极，与第二侧相邻的第二组电极，用于向电极施加电势的控制单元和该通道含有电荷分子。第一组电极被布置成使得施加电势产生空间变化的电场，该电场将带电分子限制在所述通道的预定区域内。第二组电极被布置成使得施加相对于施加到第一组电极的电位的电势产生将带电分子限制在远离通道的第二侧的区域的电场。

9. 发明授权

US08039250B2 Piezoelectric-based nanopore device for the active control of the motion of polymers through the same 有权
标题翻译：用于主动控制聚合物运动的压电基纳米孔装置
公开(公告)号：US08039250B2
公开(公告)日：2011-10-18
申请号：US12723724
申请日：2010-03-15
申请人： Hongbo Peng , Gustavo A. Stolovitzky , Stephen M. Rossnagel , Stanislav Polonsky , Binquan Luan , Glenn J. Martyna
发明人： Hongbo Peng , Gustavo A. Stolovitzky , Stephen M. Rossnagel , Stanislav Polonsky , Binquan Luan , Glenn J. Martyna
IPC分类号： C12M1/34 , C12M3/00
CPC分类号： C12Q1/6869 , Y10T29/42 , C12Q2565/631
摘要： Apparatus, system, and methods are provided for utilizing piezoelectric material for controlling a polymer through a nanopore. A reservoir is formed filled with conductive fluid. A membrane is formed that separates the reservoir. A nanopore is formed through the membrane. The membrane comprises electrical conductive layers, piezoelectric layers, and insulating layers. The piezoelectric layers are operative to control a size of the nanopore for clamping/releasing a polymer as well as to control the thickness of part of the membrane when a voltage is applied to the piezoelectric layers. Combinations of clamping/releasing the polymer and changing the thickness of part of the membrane can move a polymer through the nanopore at any electrically controlled speed and also stretch or break a polymer in the nanopore.
摘要翻译：提供了利用压电材料通过纳米孔控制聚合物的装置，系统和方法。形成填充有导电流体的储存器。形成隔离储存器的膜。通过膜形成纳米孔。膜包括导电层，压电层和绝缘层。压电层可操作以控制用于夹紧/释放聚合物的纳米孔的尺寸，以及当向压电层施加电压时控制膜的一部分的厚度。夹持/释放聚合物和改变膜的一部分厚度的组合可以以任何电控速度移动聚合物通过纳米孔，并且还拉伸或破坏纳米孔中的聚合物。

10. 发明申请

US20110223652A1 PIEZOELECTRIC-BASED NANOPORE DEVICE FOR THE ACTIVE CONTROL OF THE MOTION OF POLYMERS THROUGH THE SAME 有权
标题翻译：用于主动控制聚合物运动的基于压电陶瓷的纳米器件
公开(公告)号：US20110223652A1
公开(公告)日：2011-09-15
申请号：US12723724
申请日：2010-03-15
申请人： Hongbo Peng , Gustavo A. Stolovitsky , Stephen M. Rossnagel , Stanislav Polonsky , Binquan Luan , Glenn J. Martyna
发明人： Hongbo Peng , Gustavo A. Stolovitsky , Stephen M. Rossnagel , Stanislav Polonsky , Binquan Luan , Glenn J. Martyna
IPC分类号： G01N33/48 , G01N27/447 , C12M1/34 , H04R17/00
CPC分类号： C12Q1/6869 , Y10T29/42 , C12Q2565/631
摘要： Apparatus, system, and methods are provided for utilizing piezoelectric material for controlling a polymer through a nanopore. A reservoir is formed filled with conductive fluid. A membrane is formed that separates the reservoir. A nanopore is formed through the membrane. The membrane comprises electrical conductive layers, piezoelectric layers, and insulating layers. The piezoelectric layers are operative to control a size of the nanopore for clamping/releasing a polymer as well as to control the thickness of part of the membrane when a voltage is applied to the piezoelectric layers. Combinations of clamping/releasing the polymer and changing the thickness of part of the membrane can move a polymer through the nanopore at any electrically controlled speed and also stretch or break a polymer in the nanopore.
摘要翻译：提供了利用压电材料通过纳米孔控制聚合物的装置，系统和方法。形成填充有导电流体的储存器。形成隔离储存器的膜。通过膜形成纳米孔。膜包括导电层，压电层和绝缘层。压电层可操作以控制用于夹紧/释放聚合物的纳米孔的尺寸，以及当向压电层施加电压时控制膜的一部分的厚度。夹持/释放聚合物和改变膜的一部分厚度的组合可以以任何电控速度移动聚合物通过纳米孔，并且还拉伸或破坏纳米孔中的聚合物。

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