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    • 8. 发明授权
    • Lipase
    • 脂肪酶
    • US08207320B2
    • 2012-06-26
    • US12981929
    • 2010-12-30
    • Masahiro NakaoMasaki KanamoriHarukazu FukamiHiroaki KasaiMisa Ochiai
    • Masahiro NakaoMasaki KanamoriHarukazu FukamiHiroaki KasaiMisa Ochiai
    • C07H21/02C12N1/20C12N15/00
    • C12N9/20C12P7/6409C12P7/6436C12R1/01
    • The present invention provides a novel lipase with a molecular weight of about 32 kDa, which is produced by a strain belonging to the genus Tetrasphaera, as well as a gene encoding the same. This lipase has the ability to recognize a medium-chain fatty acid as a substrate. The present invention also provides a novel lipase with a molecular weight of about 40 kDa, which is produced by a strain belonging to the genus Tetrasphaera and has the ability to recognize both a medium-chain fatty acid and a long-chain fatty acid as substrates, as well as a polynucleotide encoding the same. The present invention further provides Tetrasphaera sp. strain NITE P-154. The lipase of the present invention can be used as an immobilized enzyme and is useful in fields such as production of digestants and/or flavorings, production of clinical laboratory reagents, detergent enzymes and/or fats, as well as production of optically active intermediates for agricultural chemicals and pharmaceutical preparations.
    • 本发明提供了一种分子量约32kDa的新型脂肪酶,其由属于四联属属的菌株产生,以及编码该脂肪酶的基因。 该脂肪酶具有识别中链脂肪酸作为底物的能力。 本发明还提供了一种分子量约40kDa的新型脂肪酶,其由属于四味子属的菌株产生,并且具有将中链脂肪酸和长链脂肪酸同时识别为底物的能力 ,以及编码该多核苷酸的多核苷酸。 本发明进一步提供了Tetrasphaera sp。 菌株NITE P-154。 本发明的脂肪酶可以用作固定化酶,可用于生产消化剂和/或调味剂,生产临床实验室试剂,洗涤剂酶和/或脂肪等领域,以及生产光学活性中间体 农药和药物制剂。
    • 9. 发明授权
    • Lipase
    • 脂肪酶
    • US07893232B2
    • 2011-02-22
    • US12096574
    • 2006-12-08
    • Masahiro NakaoMasaki KanamoriHarukazu FukamiHiroaki KasaiMisa Ochiai
    • Masahiro NakaoMasaki KanamoriHarukazu FukamiHiroaki KasaiMisa Ochiai
    • C07H21/02C12N1/20C12N15/00
    • C12N9/20C12P7/6409C12P7/6436C12R1/01
    • The present invention provides a novel lipase with a molecular weight of about 32 kDa, which is produced by a strain belonging to the genus Tetrasphaera, as well as a gene encoding the same. This lipase has the ability to recognize a medium-chain fatty acid as a substrate. The present invention also provides a novel lipase with a molecular weight of about 40 kDa, which is produced by a strain belonging to the genus Tetrasphaera and has the ability to recognize both a medium-chain fatty acid and a long-chain fatty acid as substrates, as well as a polynucleotide encoding the same. The present invention further provides Tetrasphaera sp. strain NITE P-154. The lipase of the present invention can be used as an immobilized enzyme and is useful in fields such as production of digestants and/or flavorings, production of clinical laboratory reagents, detergent enzymes and/or fats, as well as production of optically active intermediates for agricultural chemicals and pharmaceutical preparations.
    • 本发明提供了一种分子量约32kDa的新型脂肪酶,其由属于四联属属的菌株产生,以及编码该脂肪酶的基因。 该脂肪酶具有识别中链脂肪酸作为底物的能力。 本发明还提供一种分子量约40kDa的新型脂肪酶,其由属于四孢属属的菌株产生,并且具有将中链脂肪酸和长链脂肪酸同时识别为底物的能力 ,以及编码该多核苷酸的多核苷酸。 本发明进一步提供了Tetrasphaera sp。 菌株NITE P-154。 本发明的脂肪酶可以用作固定化酶,可用于生产消化剂和/或调味剂,生产临床实验室试剂,洗涤剂和/或脂肪等领域,以及生产光学活性中间体 农药和药物制剂。