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1. 发明申请

US20110002950A1 PIG EDEMA DISEASE VACCINE 有权
标题翻译： PIG EDEMA DISEATE VACCINE
公开(公告)号：US20110002950A1
公开(公告)日：2011-01-06
申请号：US12667393
申请日：2008-03-25
申请人： Kazutoshi Sawada , Kazuya Yoshida , Mayumi Yoshida , Nobuo Yoshida , Kyoko Yoshida , Takeshi Matsui , Sou-ichi Makino , Keiko Kawamoto
发明人： Kazutoshi Sawada , Kazuya Yoshida , Mayumi Yoshida , Nobuo Yoshida , Kyoko Yoshida , Takeshi Matsui , Sou-ichi Makino , Keiko Kawamoto
IPC分类号： A61K39/00 , C07H21/04 , C12N15/63 , C12N5/10 , A01H5/00
CPC分类号： C12N15/8258 , A61K39/0258 , A61K2039/517 , A61K2039/552 , C12N15/8257 , Y02A50/474
摘要： A technology for producing a pig edema disease vaccine at low cost and at high efficiency is developed. Specifically, a gene of a pig edema disease toxin protein (Stx2e protein) is efficiently expressed in plant cells to produce a plant vaccine for pig edema disease at low cost. An Stx2e protein including a secretory signal peptide derived from a plant added at an amino terminus is expressed in cells of a plant such as Lactuca sativa using the 5′-untranslated region of an alcohol dehydrogenase gene (ADH5′UTR) derived from a plant.
摘要翻译：开发了一种以低成本，高效率生产猪水肿病疫苗的技术。具体地说，猪水肿病毒素蛋白（Stx2e蛋白）的基因在植物细胞中有效表达，以低成本生产猪水肿病植物疫苗。使用源于植物的醇脱氢酶基因（ADH5'UTR）的5'-非翻译区，在植物如莴苣植物的细胞中表达包含衍生自在氨基末端添加的植物的分泌信号肽的Stx2e蛋白质。

2. 发明授权

US09080180B2 Transgenic plants expressing STX2EB protein for use as a pig edema disease vaccine 有权
标题翻译：表达STX2EB蛋白的转基因植物用作猪水肿病疫苗
公开(公告)号：US09080180B2
公开(公告)日：2015-07-14
申请号：US12667393
申请日：2008-03-25
申请人： Kazutoshi Sawada , Takeshi Matsui , Sou-ichi Makino , Keiko Kawamoto , Mayumi Yoshida , Nobuo Yoshida , Kyoko Yoshida
发明人： Kazutoshi Sawada , Kazuya Yoshida , Takeshi Matsui , Sou-ichi Makino , Keiko Kawamoto
IPC分类号： C12N15/82 , C12N15/30 , A61K39/112 , A61K39/108 , A61K39/00
CPC分类号： C12N15/8258 , A61K39/0258 , A61K2039/517 , A61K2039/552 , C12N15/8257 , Y02A50/474
摘要： A technology for producing a pig edema disease vaccine at low cost and at high efficiency is developed. Specifically, a gene of a pig edema disease toxin protein (Stx2e protein) is efficiently expressed in plant cells to produce a plant vaccine for pig edema disease at low cost. An Stx2e protein including a secretory signal peptide derived from a plant added at an amino terminus is expressed in cells of a plant such as Lactuca sativa using the 5′-untranslated region of an alcohol dehydrogenase gene (ADH5′UTR) derived from a plant.
摘要翻译：开发了一种以低成本，高效率生产猪水肿病疫苗的技术。具体地说，猪水肿病毒素蛋白（Stx2e蛋白）的基因在植物细胞中有效表达，以低成本生产猪水肿病植物疫苗。使用源于植物的醇脱氢酶基因（ADH5'UTR）的5'-非翻译区，在植物如莴苣植物的细胞中表达包含衍生自在氨基末端添加的植物的分泌信号肽的Stx2e蛋白质。

3. 发明申请

US20110231960A1 BACTERIAL TOXIN VACCINE 有权
标题翻译：细菌毒素疫苗
公开(公告)号：US20110231960A1
公开(公告)日：2011-09-22
申请号：US12990597
申请日：2009-04-28
申请人： Kazutoshi Sawada , Kazuya Yoshida , Mayumi Yoshida , Nobuo Yoshida , Kyoko Yoshida , Takeshi Matsui
发明人： Kazutoshi Sawada , Kazuya Yoshida , Mayumi Yoshida , Nobuo Yoshida , Kyoko Yoshida , Takeshi Matsui
IPC分类号： A01H5/00 , C12N15/63 , C07K19/00 , C07H21/04 , C12N5/10 , A01H5/10 , C07K7/08 , C07K14/00
CPC分类号： C07K14/245 , A61K39/00 , A61K39/0258 , A61K2039/517 , C07K14/25 , C07K14/28 , C07K2319/00 , C07K2319/55 , C12N15/8258 , Y02A50/472 , Y02A50/474
摘要： A bacterial toxin protein such as a Shiga toxin protein is efficiently produced using plant cells. The plant cells are transformed using a DNA construct containing DNA encoding a hybrid protein in which the bacterial toxin proteins such as the Shiga toxin proteins are tandemly linked through a peptide having the following characteristics (A) and (B) to produce the bacterial toxin protein in the plant cells: (A) a number of amino acids is 12 to 30; and (B) a content of proline is 20 to 35%.
摘要翻译：使用植物细胞有效地产生细菌毒素蛋白如志贺毒素蛋白质。使用含有编码杂合蛋白的DNA的DNA构建体转化植物细胞，其中细菌毒素蛋白如志贺毒素蛋白通过具有以下特征（A）和（B）的肽串联连接以产生细菌毒素蛋白在植物细胞中：（A）一些氨基酸为12〜30; （B）脯氨酸含量为20〜35％。

4. 发明授权

US08846052B2 Bacterial toxin vaccine 有权
标题翻译：细菌毒素疫苗
公开(公告)号：US08846052B2
公开(公告)日：2014-09-30
申请号：US12990597
申请日：2009-04-28
申请人： Kazutoshi Sawada , Takeshi Matsui , Mayumi Yoshida , Nobuo Yoshida , Kyoko Yoshida
发明人： Kazutoshi Sawada , Kazuya Yoshida , Takeshi Matsui
IPC分类号： A61K39/02 , C07K19/00 , A01H5/00 , C12N15/62 , C12N15/82 , C12N15/66 , A61K39/108 , C07K14/25 , C07K14/245 , A61K39/00
CPC分类号： C07K14/245 , A61K39/00 , A61K39/0258 , A61K2039/517 , C07K14/25 , C07K14/28 , C07K2319/00 , C07K2319/55 , C12N15/8258 , Y02A50/472 , Y02A50/474
摘要： A bacterial toxin protein such as a Shiga toxin protein is efficiently produced using plant cells. The plant cells are transformed using a DNA construct containing DNA encoding a hybrid protein in which the bacterial toxin proteins such as the Shiga toxin proteins are tandemly linked through a peptide having the following characteristics (A) and (B) to produce the bacterial toxin protein in the plant cells: (A) a number of amino acids is 12 to 30; and (B) a content of proline is 20 to 35%.
摘要翻译：使用植物细胞有效地产生细菌毒素蛋白如志贺毒素蛋白质。使用含有编码杂合蛋白的DNA的DNA构建体转化植物细胞，其中细菌毒素蛋白如志贺毒素蛋白通过具有以下特征（A）和（B）的肽串联连接以产生细菌毒素蛋白在植物细胞中：（A）一些氨基酸为12〜30; （B）脯氨酸含量为20〜35％。

5. 发明授权

US07691784B2 Receptor layer forming resin for thermal transfer image receptor sheet and thermal transfer image receptor sheet using the same 有权
标题翻译：用于热转印图像受体片的受体层形成树脂和使用其的热转印图像接收片
公开(公告)号：US07691784B2
公开(公告)日：2010-04-06
申请号：US11393112
申请日：2006-03-30
申请人： Masahiro Yuki , Kazuya Yoshida , Kuniyuki Doi , Hirotoshi Kizumoto
发明人： Masahiro Yuki , Kazuya Yoshida , Kuniyuki Doi , Hirotoshi Kizumoto
IPC分类号： B41M5/035 , B41M5/50
CPC分类号： B41M5/5281 , C08G18/0828 , C08G18/4676 , C08G18/664
摘要： A main object of the present invention is to provide a receptor layer forming resin which makes it possible to obtain a receptor layer for a thermal transfer image receptor sheet having excellent dyeing property. The present invention achieves the above object by providing a receptor layer forming polyurethane resin for a thermal transfer image receptor sheet obtained by copolymerizing: a high molecular weight polyol having a number average molecular weight of 1000 or higher (A); an organic isocyanate (B); and according to need, a polyol compound having a number average molecular weight of 500 or lower (C), wherein the receptor layer forming polyurethane resin for a thermal transfer image receptor sheet meets the following requirements (1) to (4): (1) the resin has at least two glass transition temperatures; (2) at least one of the glass transition temperatures is between −200 to 0° C., and at least one is between 20 to 100° C.; (3) the high molecular weight polyol (A) is a mixture comprising; an aromatic polyester polyol containing metallic base sulfonate (A-1); and a polyol other than said (A-1) (A-2); and (4) the ratio of (A-2) in the high molecular weight polyol (A) is 20 mass percent or higher.
摘要翻译：本发明的主要目的是提供一种形成受体层的树脂，其可以获得具有优异染色特性的热转印图像接受片的受体层。本发明通过提供一种通过共聚合数均分子量为1000或更高（A）的高分子量多元醇获得的热转印图像接收片的形成聚氨酯树脂的受体层形成聚氨酯树脂来实现上述目的。有机异氰酸酯（B）; 根据需要，具有数均分子量为500以下的多元醇化合物（C），其中，用于热转印影像受体片的受体层形成性聚氨酯树脂满足以下要求（1）〜（4）：（1））树脂具有至少两个玻璃化转变温度; （2）至少一个玻璃化转变温度在-200至0℃之间，并且至少一个在20至100℃之间。（3）高分子量多元醇（A）是包含：含有金属基础磺酸酯（A-1）的芳族聚酯多元醇; 和（A-1）（A-2）以外的多元醇; 和（4）高分子量多元醇（A）中的（A-2）的比例为20质量％以上。

6. 发明授权

US07553797B2 Thermal transfer recording material and thermal transfer recording method 失效
标题翻译：热转印记录材料和热转印记录方法
公开(公告)号：US07553797B2
公开(公告)日：2009-06-30
申请号：US11172712
申请日：2005-07-01
申请人： Kaori Ono , Takatugu Suzuki , Kazuya Yoshida , Hiroyuki Yamashita
发明人： Kaori Ono , Takatugu Suzuki , Kazuya Yoshida , Hiroyuki Yamashita
IPC分类号： B41M5/035 , B41M5/50
CPC分类号： B41M5/3854 , B41M5/39
摘要： A thermal transfer recording material contains at least one colorant represented by the following general formula (I): wherein R1 represents a trifluoromethyl, alkyl, aryl, alkoxy, alkoxycarbonyl, acyl, acyloxy, amide, carbamoyl, amino, or cyano group; R2 represents alkyl, acyl, carbamoyl, or alkoxycarbonyl group; R3 represents alkyl, alkenyl or aryl group; a total number of carbon atoms in R1 and R2 is 3 or more; X represents —CR4R5—, —S—, —O— or —NR6—; R4 and R5 respectively represent hydrogen, halogen, or a substituent; R6 represents hydrogen or a substituent; and Y represents an atom group required for forming a 5- to 6-memberd ring.
摘要翻译：热转印记录材料含有至少一种由以下通式（I）表示的着色剂：其中R1表示三氟甲基，烷基，芳基，烷氧基，烷氧基羰基，酰基，酰氧基，酰胺，氨基甲酰基，氨基或氰基。 R 2表示烷基，酰基，氨基甲酰基或烷氧基羰基; R3表示烷基，烯基或芳基; R1和R2中的碳原子总数为3以上; X表示-CR4R5-，-S-，-O-或-NR6-; R4和R5分别表示氢，卤素或取代基; R6表示氢或取代基; Y表示形成5-6元环所需的原子团。

7. 发明申请

US20090084147A1 ELECTRIC LOCK DEVICE 审中-公开
标题翻译：电锁装置
公开(公告)号：US20090084147A1
公开(公告)日：2009-04-02
申请号：US12211262
申请日：2008-09-16
申请人： Yukitaka Mizutani , Kazuya Yoshida , Toru Ando
发明人： Yukitaka Mizutani , Kazuya Yoshida , Toru Ando
IPC分类号： E05B47/00
CPC分类号： E05B47/0012 , E05B9/02 , E05B2009/004 , E05B2047/0017 , E05B2047/002 , E05B2047/0026 , E05B2047/0068 , E05B2047/0084 , Y10T70/7062
摘要： An electric lock device which can be used suitably regardless of an operation mode of a thumb-turn. In the electric lock device, components to be placed at a peripheral part of the thumb-turn are miniaturized by separating a control device and an electric power supply, which require a comparatively large space, from a thumb-turn cover. The electric lock device includes a cover device internally having a motor and a thumb-turn cover, a control device internally having a control part, and a power supply part built-in the control device for supplying power to the control device and the motor. Therefore, the cover device can be more compactified than that of a conventional electric lock device in which the control part and the power supply part are integrally placed with the thumb-turn cover and the motor. The cover device can be attached proximity to a thumb-turn without being protruded from a door.
摘要翻译：无论拇指转动的操作模式如何，都可以适当地使用电锁装置。在电锁装置中，通过从拇指转动盖分离需要较大空间的控制装置和电力供给，能够将配置在拇指转弯的周缘部的部件小型化。电锁装置包括内部具有电动机和拇指转动盖的盖装置，内部具有控制部的控制装置和内置有用于向控制装置和电动机供电的控制装置的电源部。因此，与传统的电锁装置相比，盖装置可以更加紧凑化，其中控制部分和电源部分与拇指转盖和电动机一体放置。盖装置可以附接到拇指转动而不从门突出。

8. 发明授权

US06229070B1 Method of stable gene expression in a transgenic plant utilizing an insulator nucleotide sequence from the sea urchin arylsulfatase gene 失效
标题翻译：利用海胆芳基硫酸酯酶基因的绝缘体核苷酸序列，在转基因植物中稳定表达基因的方法
公开(公告)号：US06229070B1
公开(公告)日：2001-05-08
申请号：US09444570
申请日：1999-11-19
申请人： Atsuhiko Shinmyo , Kazuya Yoshida , Ko Kato , Koji Akasaka , Takaaki Kusumi , Yoshikazu Tanaka
发明人： Atsuhiko Shinmyo , Kazuya Yoshida , Ko Kato , Koji Akasaka , Takaaki Kusumi , Yoshikazu Tanaka
IPC分类号： A01H500
CPC分类号： C12N15/822 , C12N15/8216
摘要： A method for the stable expression of an introduced exogenous gene in a plant or plant cell is provided. Stable expression of an exogenous gene that was introduced was achieved by operably linking an upstream sequence of sea urchin arylsulfatase gene as an insulator.
摘要翻译：提供了在植物或植物细胞中稳定表达引入的外源基因的方法。引入的外源基因的稳定表达是通过可靠地连接上游的海胆芳基硫酸酯酶基因序列作为绝缘体来实现的。

9. 发明授权

US06036002A Plastic conveyor belt and conveyor apparatus using the same 失效
标题翻译：塑料输送带和输送装置使用相同
公开(公告)号：US06036002A
公开(公告)日：2000-03-14
申请号：US862310
申请日：1997-05-23
申请人： Shogo Kobayashi , Kazuya Yoshida
发明人： Shogo Kobayashi , Kazuya Yoshida
IPC分类号： B65G17/06
CPC分类号： B65G17/063 , B65G2201/06
摘要： To provide a lightweight, rust-free conveyor which is easy to install, remove, and repair. In a plastic conveyor belt, belt element pieces which have connecting holes opening widthwise are joined by communicating the connecting holes lengthwise and are disposed at both widthwise ends. A rod is inserted in a common hole formed at a joint for connection at a lengthwise end, and the respective belt element pieces are rotatably joined around rods to form an endless belt. Rods are installed widthwise between the belt element pieces. A plastic conveyor belt is provided having plastic belt element pieces and rods composed of metallic cores and plastic sheaths, and a conveyor apparatus drives the plastic conveyor belt with a sprocket.
摘要翻译：提供轻便，无锈的输送机，易于安装，拆卸和维修。在塑料输送带中，具有宽度方向开口的连接孔的带元件片通过长度方向连通连接孔而相互连接并且设置在宽度方向两端。将杆插入形成在接头处的用于在纵向端部连接的公共孔中，并且相应的带元件片可旋转地接合在杆周围以形成环形带。杆横向安装在带元件之间。提供塑料输送带，其具有由金属芯和塑料护套组成的塑料带元件片和棒，输送装置用链轮驱动塑料输送带。

10. 发明授权

US5858628A Black thermal transfer sheet 失效
标题翻译：黑色热转印片
公开(公告)号：US5858628A
公开(公告)日：1999-01-12
申请号：US927789
申请日：1997-09-11
申请人： Kazuya Yoshida , Hiroshi Eguchi
发明人： Kazuya Yoshida , Hiroshi Eguchi
IPC分类号： B41M5/385 , B41M5/388 , B41M5/39 , C09B55/00 , C09B67/22 , G03C8/10
CPC分类号： B41M5/39 , Y10S430/165
摘要： A black thermal transfer sheet comprises a substrate film and a black dye layer formed on one surface of the substrate film. The die layer comprises dye and a binder. The dye comprises a first dye and a second dye respectively expressed by the following formulae (1) and (2): ##STR1## (where, "R.sup.1 " and "R.sup.2 " represent a substitutional or non-substitutional alkyl group, etc., "R.sup.3 " represents a hydrogen atom, etc., "R.sup.4 " represents a substitutional or non-substitutional alkyl group, etc., and "R.sup.5 " represents a substitutional or non-substitutional aminocarbonyl group, etc.; and "n" represents an integer of 1 or 2); and ##STR2## (where, "R.sup.1 ", "R.sup.2 ", "R.sup.3 " and "n" represent the same definitions as those in the formula (1), and "R.sup.6 " and "R.sup.7 " represent a substitutional or non-substitutional alkyl group, etc.).
摘要翻译：黑色热转印片包括在基材膜的一个表面上形成的基底膜和黑色染料层。模层包括染料和粘合剂。染料包括分别由下式（1）和（2）表示的第一染料和第二染料：其中，“R1”和“R2”表示取代或未取代的烷基，等等，“R3”表示氢原子等，“R4”表示取代或未取代的烷基等，“R5”表示取代或非取代氨基羰基等;“n” “表示1或2的整数）; 和（2）（其中，“R1”，“R2”，“R3”和“n”表示与式（1）中相同的定义，“R6”和“R7”表示取代或非取代烷基等）。

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