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    • 1. 发明申请
    • Stabilized, biocompatible gold nanoparticles and enviro-friendly method for making same
    • 稳定的,生物相容的金纳米颗粒和环境友好的制造方法
    • US20090074674A1
    • 2009-03-19
    • US12283935
    • 2008-09-17
    • Kattesh K. KattiRaghuraman KannanKavita K. Katti
    • Kattesh K. KattiRaghuraman KannanKavita K. Katti
    • A61K49/00A61K9/14A61K33/24
    • A61K49/0093A61K9/14A61K9/148A61K33/24A61K41/00A61K49/04
    • The invention provides stabilized, biocompatible gold nanoparticles that are stabilized with material from polyphenols- or flavanoids-rich plant material or reactive phytochemical components of the plant material. The gold nanoparticles of the invention can be fabricated with an environmentally friendly method for making biocompatible stabilized gold nanoparticles. In methods of the invention, an aqueous solution containing gold salts is mixed with polyphenols- or flavanoids-rich plant material. In preferred embodiment methods of making, an aqueous solution containing gold salts is provided. The aqueous solution is mixed with black tea, turmeric, curcumin or cinnamon or a similar naturally occurring polyphenols- or flavanoids-rich plant material. The gold salts react to form biocompatible gold nanoparticles that are stabilized with a coating of the polyphenols- or flavanoids-rich plant material. The black tea, turmeric, curcumin or cinnamon or similar naturally occurring polyphenols- or flavanoids-rich plant material can be a powder or can be in its root or bark form.
    • 本发明提供了稳定的生物相容性金纳米颗粒,其通过来自多酚 - 或富含黄酮的植物材料或植物材料的反应性植物化学成分的材料稳定。 本发明的金纳米颗粒可以用用于制备生物相容稳定的金纳米颗粒的环境友好的方法制造。 在本发明的方法中,含有金盐的水溶液与富含多酚或富含黄酮的植物材料混合。 在优选的实施方案中,提供了含有金盐的水溶液的制备方法。 水溶液与红茶,姜黄,姜黄素或肉桂或类似天然存在的多酚或富含黄酮的植物材料混合。 金盐反应形成生物相容性金纳米颗粒,其通过多酚或富含黄酮的植物材料的涂层而稳定。 红茶,姜黄,姜黄素或肉桂或类似的天然存在的多酚或富含黄酮的植物材料可以是粉末或可以是其根或树皮形式。