会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明授权
    • Aqueous atelocollagen solution and method of preparing same
    • 水性胶原纤维素溶液及其制备方法
    • US4592864A
    • 1986-06-03
    • US634253
    • 1984-07-25
    • Teruo MiyataToshio Taira
    • Teruo MiyataToshio Taira
    • A61K35/36A61K38/17C07K14/78A61K37/00C07K15/20
    • C07K14/78Y10S514/801
    • An aqueous atelocollagen solution, which can be injected into living bodies as a medical material, has a pH value in the range from about 6.5 to about 8.0 and an osmolality in the range from about 250 to about 320 mOsm/KgH.sub.2 O, and contains a phosphate buffer solution, or glucose and a phosphate buffer solution, as an agent to adjust pH and osmolality within the ranges specified above. This aqueous atelocollagen solution can be prepared by dissolving atelocollagen in an aqueous acidic solution and adding the above-mentioned pH- and osmolality-adjusting agent to the resulting solution in such an amount as to adjust pH and osmolality of the final solution within the ranges mentioned above.
    • 可以作为医疗材料注入生物体中的水溶性胶原蛋白溶液的pH值在约6.5至约8.0的范围内,重量克分子渗透压浓度在约250至约320mOsm / KgH2O范围内,并含有磷酸盐 缓冲溶液或葡萄糖和磷酸盐缓冲溶液作为调节pH和重量摩尔渗透压浓度在上述范围内的试剂。 这种水性胶原胶原溶液可以通过将胶原蛋白溶解在酸性水溶液中并将上述pH和渗透压浓度调节剂加入到所得溶液中,使得最终溶液的pH和重量克分子渗透浓度在所述范围内调节 以上。
    • 4. 发明授权
    • Man-made skin composed of two layers: collagen and a poly-alpha-amino
acid
    • 人造皮肤由两层组成:胶原蛋白和聚-α-氨基酸
    • US4642118A
    • 1987-02-10
    • US741835
    • 1985-06-06
    • Yoshimitsu KuroyanagiTeruo MiyataManabu Seno
    • Yoshimitsu KuroyanagiTeruo MiyataManabu Seno
    • A61L27/00A61F2/10A61L27/34A61L27/60
    • A61L27/60A61L27/34
    • This invention concerns a double-layered man-made skin which is prepared by laminating a collagen sponge sheet and a poly-.alpha.-amino acid membrane that has a good affinity with tissue cells and an appropriate permeability for moisture. When the man-made skin is applied on burns, cuts or wounds, the fibroblasts proliferate in the collagen sponge sheet forming a three-dimensional structure, while the epidermal cells proliferate in the region between the poly-.alpha.-amino acid membrane and a collagen sponge sheet. The poly-.alpha.-amino acid membrane plays a role in protecting affected part and in providing an optimum condition for the proliferation of fibroblasts and epidermal cells, and then it falls off as the epidermis completely regenerates. On the other hand, the collagen sponge sheet assimilates in the living tissue after having played a general role of the dermis.
    • 本发明涉及一种双层人造皮肤,其通过层叠胶原海绵片和与组织细胞具有良好亲和性并具有适当的渗透性的聚-α-氨基酸膜制备。 当人造皮肤应用于烧伤,切口或伤口时,成纤维细胞在形成三维结构的胶原海绵片中增殖,而表皮细胞在聚-α-氨基酸膜和胶原之间的区域中增殖 海绵片。 聚-α-氨基酸膜在保护受影响部位和为成纤维细胞和表皮细胞增殖提供最佳条件方面发挥作用,随着表皮完全再生,其脱落。 另一方面,在发挥真皮的一般作用后,胶原蛋白海绵片在活组织中被吸收。