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    • 1. 发明申请
    • ORAL CARE METHOD AND KIT
    • 口腔护理方法和包装
    • US20100285148A1
    • 2010-11-11
    • US12775197
    • 2010-05-06
    • Katie F. WlaschinAlan R. DombrowskiMatthew T. ScholzRanjani V. Parthasarathy
    • Katie F. WlaschinAlan R. DombrowskiMatthew T. ScholzRanjani V. Parthasarathy
    • A61K33/40A61K31/155A61P31/00
    • A61K31/155A61M16/04
    • A method of moisturizing while decolonizing mammalian tissue, the method comprising applying a multi-valent cationic antiseptic composition to the tissue, and applying a moisturizer composition to at least a portion of the same tissue; wherein the mammalian tissue is oral tissue of a subject; wherein the multi-valent cationic antiseptic is other than a metal ion; and wherein the applied compositions essentially exclude any component which causes a precipitate when combined with a multi-valent cationic antiseptic contained in the multi-valent cationic antiseptic composition when tested according to Test Method F, and/or wherein the moisturizer composition is such that a log reduction in the number of viable bacterial cells of at least 2 is provided when 106 cfu of Pseudomonas auerginosa are combined with a mixture 1.1 g of the moisturizer composition and 1.5 g of the multi-valent cationic antiseptic composition containing 0.12 weight percent of the multi-valent cationic antiseptic according to Test Method B; an oral care kit comprising a composition comprising the multi-valent cationic antiseptic and the moisturizer composition; and a method of moisturizing oral tissue of a patient requiring intubation using the moisturizer composition and an endotracheal tube coated or impregnated with a cationic antiseptic are provided.
    • 一种在哺乳动物组织非殖化时保湿的方法,该方法包括将多价阳离子防腐组合物施用于组织,以及将保湿组合物施用于相同组织的至少一部分; 其中哺乳动物组织是受试者的口腔组织; 其中所述多价阳离子防腐剂不是金属离子; 并且其中当根据测试方法F测试时,所施加的组合物基本上排除任何与多价阳离子防腐组合物中所含的多价阳离子防腐剂组合时引起沉淀的组分,和/或其中所述保湿组合物使得 当将106cfu的绿脓假单胞菌与1.1g的保湿组合物和1.5g多价阳离子防腐组合物混合在一起时,提供至少为2的活细菌细胞的数量减少,该组合物含有0.12重量%的多 根据测试方法B的阳离子抗菌剂; 口腔护理套件,其包含包含所述多价阳离子防腐剂和所述保湿组合物的组合物; 提供了使用保湿组合物和使用阳离子防腐剂涂布或浸渍的气管内导管的需要插管的患者的口腔组织的保湿方法。
    • 2. 发明授权
    • Oral care method and kit
    • 口腔护理方法和试剂盒
    • US08460689B2
    • 2013-06-11
    • US12775197
    • 2010-05-06
    • Katie F. WlaschinAlan R. DombrowskiMatthew T. ScholzRanjani V. Parthasarathy
    • Katie F. WlaschinAlan R. DombrowskiMatthew T. ScholzRanjani V. Parthasarathy
    • A61K8/43A61K6/00A61K31/155
    • A61K31/155A61M16/04
    • A method of moisturizing while decolonizing mammalian tissue, the method comprising applying a multi-valent cationic antiseptic composition to the tissue, and applying a moisturizer composition to at least a portion of the same tissue; wherein the mammalian tissue is oral tissue of a subject; wherein the multi-valent cationic antiseptic is other than a metal ion; and wherein the applied compositions essentially exclude any component which causes a precipitate when combined with a multi-valent cationic antiseptic contained in the multi-valent cationic antiseptic composition when tested according to Test Method F, and/or wherein the moisturizer composition is such that a log reduction in the number of viable bacterial cells of at least 2 is provided when 106 cfu of Pseudomonas aeruginosa are combined with a mixture 1.1 g of the moisturizer composition and 1.5 g of the multi-valent cationic antiseptic composition containing 0.12 weight percent of the multi-valent cationic antiseptic according to Test Method B; an oral care kit comprising a composition comprising the multi-valent cationic antiseptic and the moisturizer composition; and a method of moisturizing oral tissue of a patient requiring intubation using the moisturizer composition and an endotracheal tube coated or impregnated with a cationic antiseptic are provided.
    • 一种在哺乳动物组织非殖化时保湿的方法,该方法包括将多价阳离子防腐组合物施用于组织,以及将保湿组合物施用于相同组织的至少一部分; 其中哺乳动物组织是受试者的口腔组织; 其中所述多价阳离子防腐剂不是金属离子; 并且其中当根据测试方法F测试时,所施加的组合物基本上排除任何与多价阳离子防腐组合物中所含的多价阳离子防腐剂组合时引起沉淀的组分,和/或其中所述保湿组合物使得 当将106 cfu的绿脓假单胞菌与1.1g的保湿组合物和1.5g多价阳离子防腐剂组合物混合在一起时,提供至少2个活细菌细胞数目的对数减少,该组合物含有0.12重量%的多 根据测试方法B的阳离子抗菌剂; 口腔护理套件,其包含包含所述多价阳离子防腐剂和所述保湿组合物的组合物; 提供了使用保湿组合物和使用阳离子防腐剂涂布或浸渍的气管内导管的需要插管的患者的口腔组织的保湿方法。
    • 4. 发明申请
    • SUCTION SWAB AND METHOD OF MAKING SAME
    • SUCTION SWAB及其制作方法
    • US20110151405A1
    • 2011-06-23
    • US12961558
    • 2010-12-07
    • Alan R. Dombrowski
    • Alan R. Dombrowski
    • A61C17/08
    • A61M16/0436A61C17/08A61M1/008A61M16/0463A61M2210/0625
    • A suction swab and a method of making a suction swab. The suction swab can include a shaft, a pad coupled to the shaft, and an aperture formed through the pad and the shaft. The shaft can be elongated and can have a lumen, a longitudinal direction and an outer transverse dimension oriented substantially perpendicularly with respect to the longitudinal direction. The shaft can include a proximal end and a distal end. The proximal end can be coupled to a suction source. The aperture can be in fluid communication with the lumen of the shaft, can be elongated, and can have a width and a length greater than the width. The length of the aperture can be greater than the outer transverse dimension of the shaft. The method can include coupling the pad to the distal end of the shaft, and forming an aperture through the pad and the shaft.
    • 抽吸拭子和抽吸拭子的方法。 抽吸拭子可以包括轴,耦合到轴的垫以及通过垫和轴形成的孔。 轴可以是细长的,并且可以具有相对于纵向方向基本上垂直定向的内腔,纵向方向和外横向尺寸。 轴可以包括近端和远端。 近端可以联接到抽吸源。 孔可以与轴的内腔流体连通,可以是细长的,并且可以具有大于宽度的宽度和长度。 孔的长度可以大于轴的外横向尺寸。 该方法可以包括将垫连接到轴的远端,并且通过垫和轴形成孔。
    • 5. 发明授权
    • Suction handle, suction handle assembly, and oral care systems comprising same
    • 抽吸把手,抽吸把手组件和包括其的口腔护理系统
    • US08747111B2
    • 2014-06-10
    • US13695311
    • 2011-04-27
    • Alan R. DombrowskiClark F. Bow
    • Alan R. DombrowskiClark F. Bow
    • A61C17/06
    • A61M1/0047A61C17/043
    • A suction handle, a suction handle assembly, and an oral care system. The suction handle can include a first axis oriented along a longitudinal direction, a first conduit having a first bore oriented along the first axis, and a second conduit adapted to be coupled to the first conduit, which can have a second bore oriented along the first axis. The first conduit and the second conduit can be movable with respect to one another in the longitudinal direction between a first position in which there is no fluid communication between the first and second bores, and a second position in which there is fluid communication. An actuator can be coupled to at least one of the first conduit and the second conduit that which can pivot about a second axis oriented substantially perpendicularly with respect to the first axis between a first and second actuator position.
    • 抽吸手柄,抽吸手柄组件和口腔护理系统。 抽吸手柄可以包括沿着纵向方向定向的第一轴线,具有沿着第一轴线定向的第一孔的第一管道和适于联接到第一管道的第二管道,第二管道可以具有沿着第一管道 轴。 第一管道和第二管道可以在第一位置和第二位置之间相对于彼此在第一位置和第二位置之间相对于第一位置和第二位置之间移动。 致动器可以联接到第一管道和第二管道中的至少一个,其可以围绕第一和第二致动器位置相对于第一轴线大致垂直地取向的第二轴线枢转。
    • 7. 发明申请
    • SUCTION ORAL BRUSH
    • 戒指口腔刷
    • US20110151404A1
    • 2011-06-23
    • US12960799
    • 2010-12-06
    • Alan R. Dombrowski
    • Alan R. Dombrowski
    • A61C17/08
    • A46B15/00A46B15/0053A46B2200/1066
    • A suction oral brush. The oral brush can include a handle having a longitudinal direction and a lumen, and can be adapted to be coupled to a suction source. Bristles can extend outwardly of a first side of a distal end of the handle. A proximal aperture can be formed in the first side of the distal end of the handle that is in fluid communication with the lumen of the handle. The proximal aperture can include a distal end and a proximal end positioned no further distally than a proximal end of the bristles. A distal aperture in fluid communication with the lumen can be formed in a sidewall of the distal end of the handle, and can have a width greater than its height. The bristles can be arranged such that none of the bristles lie on the centerline of the distal end of the handle.
    • 抽吸口腔刷。 口腔刷可以包括具有纵向方向和内腔的手柄,并且可以适于联接到抽吸源。 刷毛可以从手柄的远端的第一侧向外延伸。 近端孔口可以形成在手柄的远端的与手柄的内腔流体连通的第一侧。 近端孔可以包括远端和远端远离刷毛的近端的近端。 可以在手柄的远端的侧壁中形成与内腔流体连通的远端孔,并且可以具有大于其高度的宽度。 刷毛可以布置成使得没有刷毛位于手柄的远端的中心线上。
    • 9. 发明申请
    • SUCTION HANDLE, SUCTION HANDLE ASSEMBLY, AND ORAL CARE SYSTEMS COMPRISING SAME
    • 吸烟手柄,吸烟手铐组装及口腔护理系统
    • US20130052610A1
    • 2013-02-28
    • US13695311
    • 2011-04-27
    • Alan R. DombrowskiClark F. Bow
    • Alan R. DombrowskiClark F. Bow
    • A61C17/08A61C17/12
    • A61M1/0047A61C17/043
    • A suction handle, a suction handle assembly, and an oral care system. The suction handle can include a first axis oriented along a longitudinal direction, a first conduit having a first bore oriented along the first axis, and a second conduit adapted to be coupled to the first conduit, which can have a second bore oriented along the first axis. The first conduit and the second conduit can be movable with respect to one another in the longitudinal direction between a first position in which there is no fluid communication between the first and second bores, and a second position in which there is fluid communication. An actuator can be coupled to at least one of the first conduit and the second conduit that which can pivot about a second axis oriented substantially perpendicularly with respect to the first axis between a first and second actuator position.
    • 抽吸手柄,抽吸手柄组件和口腔护理系统。 抽吸手柄可以包括沿着纵向方向定向的第一轴线,具有沿着第一轴线定向的第一孔的第一管道和适于联接到第一管道的第二管道,第二管道可以具有沿着第一管道 轴。 第一管道和第二管道可以在第一位置和第二位置之间相对于彼此在第一位置和第二位置之间相对于第一位置和第二位置之间移动。 致动器可以联接到第一管道和第二管道中的至少一个,其可以围绕第一和第二致动器位置相对于第一轴线大致垂直地取向的第二轴线枢转。