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1. 发明授权

US09926580B2 Process for producing coenzyme Q10 有权
公开(公告)号：US09926580B2
公开(公告)日：2018-03-27
申请号：US15076025
申请日：2016-03-21
申请人： KANEKA CORPORATION
发明人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
IPC分类号： C12P7/66 , C12P7/22
CPC分类号： C12P7/66 , C12P7/22
摘要： A process for producing on an industrial scale the oxidized coenzyme Q10, includes culturing a reduced coenzyme Q10-producing microorganism selected from the group consisting of the genus Rhodobacter, the genus Saitoella, the genus Schizosaccharomyces and the genus Trichosporon, to obtain microbial cells containing reduced coenzyme Q10 at a ratio of not less than 70 mole % among the entire coenzymes Q10; and one of: (a) oxidizing thus-obtained reduced coenzyme Q10 to oxidized coenzyme Q10 and then extracting the oxidized coenzyme Q10 by an organic solvent; or (b) extracting reduced coenzyme Q10 by an organic solvent and oxidizing the extracted reduced coenzyme Q10 to oxidized coenzyme Q10.

2. 发明申请

US20190127773A1 METHOD FOR PRODUCING COENZYME Q10 审中-公开
公开(公告)号：US20190127773A1
公开(公告)日：2019-05-02
申请号：US16233392
申请日：2018-12-27
申请人： KANEKA CORPORATION
发明人： Wan Ying LEE , Yasuyuki Suzuki , Akihisa Kanda
IPC分类号： C12P23/00 , B01J20/20 , B01J20/18 , B01D15/00 , B01J20/22
摘要： A method of producing coenzyme Q10 includes contacting an extract from a coenzyme Q10-producing microorganism with an adsorbent (A) such that the adsorbent (A) adsorbs a component of the extract other than coenzyme Q10, and that coenzyme Q10 is obtained. The adsorbent (A) includes aluminum silicate at a content of 50% or more.

3. 发明申请

US20200208189A9 METHOD FOR PRODUCING COENZYME Q10 审中-公开
公开(公告)号：US20200208189A9
公开(公告)日：2020-07-02
申请号：US16233392
申请日：2018-12-27
申请人： KANEKA CORPORATION
发明人： Wan Ying LEE , Yasuyuki Suzuki , Akihisa Kanda
IPC分类号： C12P23/00 , B01J20/20 , B01J20/18 , B01D15/00 , B01J20/22
摘要： A method of producing coenzyme Q10 includes contacting an extract from a coenzyme Q10-producing microorganism with an adsorbent (A) such that the adsorbent (A) adsorbs a component of the extract other than coenzyme Q10, and that coenzyme Q10 is obtained. The adsorbent (A) includes aluminum silicate at a content of 50% or more.

4. 发明申请

US20160304915A1 PROCESS FOR PRODUCING COENZYME Q10 审中-公开
标题翻译：生产聚苯乙烯Q10的方法
公开(公告)号：US20160304915A1
公开(公告)日：2016-10-20
申请号：US15076025
申请日：2016-03-21
申请人： KANEKA CORPORATION
发明人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
IPC分类号： C12P7/66
CPC分类号： C12P7/66 , C12P7/22
摘要： A process for producing on an industrial scale the oxidized coenzyme Q10, includes culturing a reduced coenzyme Q10-producing microorganism selected from the group consisting of the genus Rhodobacter, the genus Saitoella, the genus Schizosaccharomyces and the genus Trichosporon, to obtain microbial cells containing reduced coenzyme Q10 at a ratio of not less than 70 mole % among the entire coenzymes Q10; and one of: (a) oxidizing thus-obtained reduced coenzyme Q10 to oxidized coenzyme Q10 and then extracting the oxidized coenzyme Q10 by an organic solvent; or (b) extracting reduced coenzyme Q10 by an organic solvent and oxidizing the extracted reduced coenzyme Q10 to oxidized coenzyme Q10.
摘要翻译：一种在工业规模上生产氧化型辅酶Q10的方法，包括培养选自Rhodobacter属，Saitoella属，粟酒裂殖酵母属和Trichosporon属的还原型辅酶Q10产生微生物，以获得含有还原型辅酶Q10在整个辅酶Q10中的比例不小于70摩尔％; 和（a）将由此得到的还原型辅酶Q10氧化成氧化型辅酶Q10，然后用有机溶剂萃取氧化型辅酶Q10; 或（b）用有机溶剂萃取还原型辅酶Q10，将提取的还原型辅酶Q10氧化成氧化型辅酶Q10。

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