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1. 发明申请

US20050211571A1 Electrochemical detection method and device 失效
标题翻译：电化学检测方法及装置
公开(公告)号：US20050211571A1
公开(公告)日：2005-09-29
申请号：US10517436
申请日：2003-06-23
申请人： Jurgen Schulein , Bjorn Grassl , Jorg Hassmann
发明人： Jurgen Schulein , Bjorn Grassl , Jorg Hassmann
IPC分类号： G01N33/53 , G01N27/416 , G01N27/48 , G01N27/49 , G01N33/487 , G01N33/543 , G01N37/00 , G01N27/26
CPC分类号： G01N27/3277
摘要： The invention relates to a device for the electrochemical detection of at least one biochemical molecule—contained in a liquid—from a group of predetermined biochemical molecules, having a means (1) for taking up the liquid, said means having at least one reference electrode (RE) and at least one counterelectrode (GE) and also a multiplicity of working electrodes (AE1, AE2, AE3), at least one working electrode (AE1, AE2, AE3) being provided for the detection of each biochemical molecule, said working electrode being coated with a molecule that is complementary to the respective biochemical molecule, so that the biochemical molecules can be detected simultaneously, a potentiostat (P) for generating a predetermined voltage profile between the working electrodes (AE1, AE2, AE3) and the reference electrode (RE), a current/voltage converter (S1, S2, S3) being connected downstream of each of the working electrodes (AE1, AE2, AE3), the current/voltage converters (S1, S2, S3) holding all of the working electrodes (AE1, AE2, AE3) at the same potential and a means (Ad) for measuring the currents flowing through the working electrodes (AE1, AE2, AE3).
摘要翻译：本发明涉及一种用于电化学检测来自一组预定生物化学分子的液体中至少一种生化分子的装置，其具有用于吸收液体的装置（1），所述装置具有至少一个参比电极（RE）和至少一个反电极（GE）以及多个工作电极（AE 1，AE 2，AE 3），至少一个工作电极（AE 1，AE 2，AE 3）用于检测每个生物化学分子，所述工作电极涂覆有与相应的生物化学分子互补的分子，使得可以同时检测生物化学分子;用于在工作电极之间产生预定电压分布的恒电位仪（P） AE 2，AE 3）和参考电极（RE），连接在每个工作电极（AE 1，AE 2，AE 3）的下游的电流/电压转换器（S 1，S 2，S 3）电流/电压转换器将所有工作电极（AE 1，AE 2，AE 3）保持在相同电位的S（S 1，S 2，S 3）和用于测量流过工作电极的电流（AE 1， AE 2，AE 3）。

2. 发明申请

US20060011474A1 Device for detecting an analyte 审中-公开
标题翻译：用于检测分析物的装置
公开(公告)号：US20060011474A1
公开(公告)日：2006-01-19
申请号：US10518498
申请日：2003-06-27
申请人： Jurgen Schulein , Christine Kugler , Burcu Meric , Hans Kosak , Jorg Hassmann , Bjorn Grassl , Dirk Kuhlmeier
发明人： Jurgen Schulein , Christine Kugler , Burcu Meric , Hans Kosak , Jorg Hassmann , Bjorn Grassl , Dirk Kuhlmeier
IPC分类号： G01N27/26 , G01N33/487
CPC分类号： G01N27/3276 , G01N27/308 , Y10T29/49002
摘要： The invention relates to a device (17) for detecting an analyte in a liquid having a multitude of electrodes (15), which are insulated from one another while being arranged on a first side (12) of an electrically non-conductive plate (10) that is impermeable to the liquid. Said electrodes (15) have, at least in part, an analyte-specific coating or analyte-specific molecules. Electrical conductors that pass through the plate (10) can, from a second side (14) of the plate, be electrically contacted and individually discharged. The coating or the molecules has/have a specific affinity to the analytes or to a substance formed due to the presence of the analyte. In addition, the device has no leakages.
摘要翻译：本发明涉及一种用于检测具有多个电极（15）的液体中的分析物的装置（17），它们彼此绝缘，同时被布置在非导电板（10）的第一侧（12）上）对液体是不透水的。所述电极（15）至少部分具有分析物特异性涂层或分析物特异性分子。穿过板（10）的电导体可以从板的第二侧（14）电接触并单独排出。涂层或分子对分析物或由于分析物的存在形成的物质具有特异性亲和力。此外，该设备没有泄漏。

3. 发明申请

US20070048194A1 Use of a disposable container, microfluidic device and method for processing molecules 审中-公开
标题翻译：使用一次性容器，微流体装置和处理分子的方法
公开(公告)号：US20070048194A1
公开(公告)日：2007-03-01
申请号：US10563279
申请日：2003-07-15
申请人： Jurgen Schulein , Bjoern Grassel , Juergen Krause , Roland Barten , Dirk Kuhlmeier , Joerg Hassmann , Hans Kosak
发明人： Jurgen Schulein , Bjoern Grassel , Juergen Krause , Roland Barten , Dirk Kuhlmeier , Joerg Hassmann , Hans Kosak
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/565 , B01L2200/027 , B01L2200/04 , B01L2200/141 , B01L2200/16 , B01L2300/021 , B01L2300/022 , B01L2400/0478
摘要： The invention relates to the use of a disposable container comprising a cylindcr (1) containing a plunger (2, 24) that is displaceably guided in said cylinder and a connection (3) that is provided on a first end (E1) of the cylinder (1) lying opposite the plunger (2, 24), said container being designed to create a difference in pressure in a microfluidic device (13) to hold (6) an agent (F, P) for processing molecules and/or to act as a reaction vessel.
摘要翻译：本发明涉及一次性容器的使用，该容器包括一个包含柱塞（2,24）的圆柱形件（1），该柱塞可移动地被引导到所述缸体中;以及连接件（3），其设在所述缸体的第一端（E 1）上所述容器设计成在微流体装置（13）中产生压力差，以保持（6）用于处理分子的试剂（F，P）和/或作为反应容器。

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